Structural basis for angiopoietin-1-mediated signaling initiation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 18, 2013, Pages 7205-7210

  Yu, Xuehong ^a   Seegar, Tom C M ^b   Dalton, Annamarie C ^b   Tzvetkova Robev, Dorothea ^a   Goldgur, Yehuda ^a   Rajashankar, Kanagalaghatta R ^c   Nikolov, Dimitar B ^a   Barton, William A ^b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c ARGONNE NATIONAL LABORATORY   (United States)

Author keywords

Cellular signaling; Tie receptor tyrosine kinase; X ray crystallography

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN 2; ANGIOPOIETIN RECEPTOR;

ARTICLE; CELL MANIPULATION; CELL STRAIN HEK293; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

ANGIOPOIETIN-1; ANGIOPOIETIN-2; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; HEK293 CELLS; HUMANS; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, TIE-1; RECEPTOR, TIE-2; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; STATIC ELECTRICITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84876893871     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1216890110     Document Type: Article

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