DNA Methylation Profile Distinguishes Clear Cell Sarcoma of the Kidney from Other Pediatric Renal Tumors

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Ueno, Hitomi ^a   Okita, Hajime ^a   Akimoto, Shingo ^a   Kobayashi, Kenichiro ^a   Nakabayashi, Kazuhiko ^a   Hata, Kenichiro ^a   Fujimoto, Junichiro ^b   Hata, Jun ichi ^c   Fukuzawa, Masahiro ^d   Kiyokawa, Nobutaka ^a  

^a NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^b NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^c TOKIWA UNIVERSITY   (Japan)

^d RESEARCH INSTITUTE FOR MATERNAL AND CHILD HEALTH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOC GENE; ARTICLE; CANCER CLASSIFICATION; CARCINOGENESIS; CHILDHOOD CANCER; CLEAR CELL SARCOMA; CLUSTER ANALYSIS; CONTROLLED STUDY; CPG ISLAND; CREG1 GENE; DNA METHYLATION; EPIGENETICS; EWING SARCOMA KIDNEY TUMOR; GENE FREQUENCY; GENE LOCUS; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; KIDNEY SARCOMA; KIDNEY TUMOR; MAJOR CLINICAL STUDY; NEPHROBLASTOMA; NUCLEOTIDE SEQUENCE; ONCOGENE; PKN1 GENE; RHABDOID KIDNEY TUMOR; THROMBOSPONDIN 1 GENE; VALIDATION PROCESS;

CHILD; CLUSTER ANALYSIS; CPG ISLANDS; DIAGNOSIS, DIFFERENTIAL; DNA METHYLATION; GENES, NEOPLASM; HUMANS; KIDNEY; KIDNEY NEOPLASMS; RESTRICTION MAPPING; SARCOMA, CLEAR CELL;

EID: 84876884022     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0062233     Document Type: Article

References (29)

1. Eble JN, Sauter G, Epstein JI, Sesterhenn IA (2004) World Health Organization Classification of Tumours: Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. Lyon: IARC Press. p48-61.
2. Rubin BP, Chen CJ, Morgan TW, Xiao S, Grier HE, et al. (1998) Congenital mesoblastic nephroma t(12;15) is associated with ETV6-NTRK3 gene fusion: cytogenetic and molecular relationship to congenital (infantile) fibrosarcoma. Am J Pathol. 153: 1451-1458.
3. Argani P, Perlman EJ, Breslow NE, Browning NG, Green DM, et al. (2000) Clear cell sarcoma of the kidney: a review of 351 cases from the National Wilms Tumor Study Group Pathology Center. Am J Surg Pathol 24: 4-18.
4. Versteege I, Sevenet N, Lange J, Rousseau-Merck MF, Ambros P, et al. (1998) Truncating mutations of hSNF5/INI1 in aggressive pediatric cancer. Nature 394: 203-206.
5. Biegel JA, Tan L, Zhang F, Wainwright L, Russo P, et al. (2002) Alterations of the hSNF5/INI1 gene in central nervous system atypical teratoid/rhabdoid tumors and renal and extrarenal rhabdoid tumors. Clin Cancer Res 8: 3461-3467.
6. Imbalzano AN, Jones SN, (2005) Snf5 tumor suppressor couples chromatin remodeling, checkpoint control, and chromosomal stability. Cancer Cell 7: 294-295.
7. Beckwith JB (1994) Renal neoplasms of childhood. 2nd ed. In: Sternberg SS, editor. Diagnostic surgical pathology. New York: Raven Press. 1741-1766.
8. Schuster AE, Schneider DT, Fritsch MK, Grundy P, Perlman EJ, (2003) Genetic and genetic expression analyses of clear cell sarcoma of the kidney. Lab Invest 83: 1293-1299.
9. Baylin SB, Belinsky SA, Herman JG, (2000) Aberrant methylation of gene promoters in cancer-concepts, misconcepts, and promise. J Natl Cancer Inst 92: 1460-1461.
10. Feinberg AP, Tycko B, (2004) The history of cancer epigenetics. Nat Rev Cancer 4: 143-153.
11. Esteller M, (2002) CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future. Oncogene 21: 5427-5440.
12. Herman JG, Baylin SB, (2003) Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 349: 2042-2054.
13. Anglesio MS, Evdokimova V, Melnyk N, Zhang L, Fernandez CV, et al. (2004) Differential expression of a novel ankyrin containing E3 ubiquitin-protein ligase, Hace1, in sporadic Wilms' tumor versus normal kidney. Hum Mol Genet. 13(18): 2061-2074.
14. Haruta M, Matsumoto Y, Izumi H, Watanabe N, Fukuzawa M, et al. (2008) Combined BuR1 protein down-regulation and RASSF1A hypermethylation in Wilms tumors with diverse cytogenetic change. Mol Carcinog. 47(9): 660-666.
15. Szemes M, Dallosso AR, Melegh Z, Curry T, Li Y, et al. (2013) Control of epigenetic states by WT1 via regulation of de novo DNA methyltransferase 3A. Hum Mol Genet. 22(1): 74-83.
16. Chilukamarri L, Hancock AL, Malik S, Zabkiewicz J, Baker JA, et al. (2007) Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors. Neoplasia. (11): 970-978.
17. Esteller M, Herman JG, (2004) Generating mutations but providing chemosensitivity: the role of O6-methylguanine DNA methyltransferase in human cancer. Oncogene. 23(1): 1-8.
18. Yu J, Ni M, Xu J, Zhang H, Gao B, et al. (2002) Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis. J.BMC Cancer. 2: 29.
19. O'Meara E, Stack D, Lee CH, Garvin AJ, Morris T, et al. (2012) Characterization of the chromosomal translocation t(10;17)(q22;p13) in clear cell sarcoma of kidney. J Pathol. 227(1): 72-80.
20. Goto Y, Shinjo K, Kondo Y, Shen L, Toyota M, et al. (2009) Epigenetic profiles distinguish malignant pleural mesothelioma from lung adenocarcinoma. Cancer Res. 69(23): 9073-9082.
21. Mahoney SE, Yao Z, Keyes CC, Tapscott SJ, Diede SJ, (2012) Genome-wide DNA methylation studies suggest distinct DNA methylation patterns in pediatric embryonal and alveolar rhabdomyosarcomas. Epigenetics 7(4): 400-408.
22. Guo W, Dong Z, He M, Guo Y, Guo J, et al. (2010) Aberrant methylation of thrombospondin-1 and its association with reduced expression in gastric cardia adenocarcinoma. J Biomed Biotechnol 721485 Epub 2010 Mar 15.
23. Guerrero D, Guarch R, Ojer A, Casas JM, Ropero S, et al. (2008) Hypermethylation of the thrombospondin-1 gene is associated with poor prognosis in penile squamous cell carcinoma. BJU Int. 102: 747-755.
24. Lawler J, (2002) Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth. J Cell Mol Med 6: 1-12.
25. Folkman J, (2004) Endogenous angiogenesis inhibitors. APMIS 112: 496-507.
26. Greenaway J, Lawler J, Moorehead R, Bornstein P, Lamarre J, et al. (2007) Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1). J Cell Physiol 210: 807-818.
27. Wang S, Wu Z, Sorenson CM, Lawler J, Sheibani N, (2003) Thrombospondin-1-deficient mice exhibit increased vascular density during retinal vascular development and are less sensitive to hyperoxia-mediated vessel obliteration. Dev Dyn 228: 630-642.
28. Lawler J, Miao WM, Duquette M, Bouck N, Bronson RT, et al. (2001) Thrombospondin-1 gene expression affects survival and tumor spectrum of p53-deficient mice. Am J Pathol 159: 1949-1956.
29. Sund M, Hamano Y, Sugimoto H, Sudhakar A, Soubasakos M, et al. (2005) Function of endogenous inhibitors of angiogenesis as endothelium-specific tumor suppressors. Proc Natl Acad Sci USA 102: 2934-2939.