Pharmacological studies of performance on the free-operant psychophysical procedure

Behavioural Processes

Volumn 95, Issue , 2013, Pages 71-89

  Body, S ^a   Cheung, T H C ^a,b   Valencia Torres, L ^a,c   Olarte Sanchez C M ^a,d   Fone, K C F ^a   Bradshaw, C M ^a   Szabadi, E ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b ARIZONA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

5 HT receptors; Corpus striatum; Dopamine receptors; Free operant psychophysical procedure; Interval timing; Prefrontal cortex

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; 6 CHLORO 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; DEXAMPHETAMINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; FENFLURAMINE; KETANSERIN; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN 3A RECEPTOR; VOLINANSERIN;

DATA ACQUISITION; DIFFERENTIATION; REINFORCEMENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLOGICAL MODEL; BRAIN CORTEX LESION; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC TRANSMISSION; EVOKED CORTICAL RESPONSE; FEMALE; FREE OPERANT PSYCHOPHYSICAL PROCEDURE; MENTAL PERFORMANCE; MOLECULAR MODEL; NEUROANATOMY; NEUROMODULATION; NEUROPHARMACOLOGY; NONHUMAN; NUCLEUS ACCUMBENS; PREFRONTAL CORTEX; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PSYCHOMETRY; PSYCHOPHYSIOLOGY; RAT; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; REINFORCEMENT; SYNAPTIC TRANSMISSION;

ANIMALS; BEHAVIOR, ANIMAL; CONDITIONING, OPERANT; CORPUS STRIATUM; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; FEMALE; PREFRONTAL CORTEX; QUINOLINIC ACID; RATS; RATS, WISTAR; SEROTONIN ANTAGONISTS;

EID: 84876877602     PISSN: 03766357     EISSN: 18728308     Source Type: Journal    
DOI: 10.1016/j.beproc.2013.02.004     Document Type: Article

References (101)

1. Alex K.D., Pehek E.A. Pharmacologic mechanisms of serotonergic regulation of dopamine neurotransmission. Pharmacol. Therap. 2007, 113:296-320.
2. Alexander G.E., DeLong M.R., Strick P.L. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Ann. Rev. Neurosci. 1990, 9:357-381.
3. Alexander M., Rothman R.B., Baumann M.H., Endres C.J., Brasic J.R., Wong D.F. Noradrenergic and dopaminergic effects of (+)-amphetamine-like stimulants in the baboon Papio anubis. Synapse 2005, 56:94-99.
4. Alexander S.P.H., Mathie A., Peters J.A. Guide to receptors and channels (GRAC), 5th edition. Br. J. Pharmacol. 2011, 164(suppl. 1):S1-S324.
5. Al-Ruwaitea A.S.A., Al-Zahrani S.S.A., Ho M.-Y., Bradshaw C.M., Szabadi E. 5-Hydroxytryptamine and interval timing. Time and Behaviour: Psychological and Neurobehavioural Analyses 1997, 517-570. Elsevier, Amsterdam. C.M. Bradshaw, E. Szabadi (Eds.).
6. Al-Ruwaitea A.S.A., Chiang T.-J., Ho M.-Y., Bradshaw C.M., Szabadi E. Effect of central 5-hydroxytryptamine depletion on changeover behaviour in concurrent schedules of reinforcement. Psychopharmacology (Berl) 1999, 144:264-271.
7. Al-Zahrani S.S.A., Ho M.-Y., Velazquez Martinez D.N., Lopez Cabrera M., Bradshaw C.M., Szabadi E. Effect of destruction of the 5-hyroxytryptaminergic pathways on behavioural timing and " switching" in a free-operant psychophysical procedure. Psychopharmacology (Berl) 1996, 127:346-352.
8. 2A receptor stimulation on the discrimination of durations by rats. Behav. Pharmacol. 2005, 17:51-59.
9. 2A receptor stimulation on temporal differentiation performance in the fixed-interval peak procedure. Behav. Processes 2006, 71:250-257.
10. Barnes N.M., Sharp T. A review of central 5-HT receptors and their function. Neuropharmacology 1999, 38:1083-1152.
11. Basar K., Sesia T., Groenenwegen H., Steinbusch H.W.M., Visser-Vanderwalle V., Temel Y. Nucleus accumbens and impulsivity. Prog. Neurobiol. 2010, 92:533-557.
12. Bayley P.J., Bentley G.D., Dawson G.R. The effects of selected antidepressant drugs on timing behaviour in rats. Psychopharmacology (Berl) 1998, 136:114-122.
13. Beaulieu J.-M., Gainetdinov R.R. The physiology, signaling, and pharmacology of dopamine receptors. Pharmacol. Rev. 2011, 63:182-217.
14. Bezzina G., Cheung T.H.C., Asgari K., Hampson C.L., Body S., Bradshaw C.M., Szabadi E., Anderson I.M., Deakin J.F.W. Effects of quinolinic acid-induced lesions of the nucleus accumbens core on inter-temporal choice: a quantitative analysis. Psychopharmacology (Berl) 2007, 195:71-84.
15. Bizo L.A., White K.G. The behavioral theory of timing: reinforcer rate determines pacemaker rate. J. Exp. Anal. Behav. 1994, 61:19-33.
16. Bizo L.A., White K.G. Pacemaker rate and the behavioral theory of timing. J. Exp. Psychol. Anim. Behav. Process. 1994, 20:308-321.
17. Bizo L.A., White K.G. Timing with controlled reinforcer density: implications for models of timing. J. Exp. Psychol. Anim. Behav. Process. 1997, 23:44-55.
18. Bockaert J., Claeysen S., Dumuis A., Marin P. Classification and signaling characteristics of 5-HT receptors. Handbook of the Behavioral Neurobiology of Serotonin 2010, vol. 21:103-121. Elsevier, Amsterdam.
19. 2 receptor stimulation on temporal differentiation is not mediated by receptors in the dorsal striatum. Behav. Processes 2006, 71:258-267.
20. 3 receptors in interval timing behaviour. Psychopharmacology (Berl) 2005, 181:289-298.
21. 2A receptors. Psychopharmacology (Berl) 2006, 189:331-343.
22. Body S., Cheung T.H.C., Hampson C.L., den Boon F.S., Bezzina G., Fone K.C.F., Bradshaw C.M., Szabadi E. Attenuation of the effects of d-amphetamine on interval timing behaviour by central 5-hydroxytryptamine depletion. Psychopharmacology (Berl) 2009, 203:547-559.
23. Body S., Chiang T.-J., Mobini S., Ho M.-Y., Bradshaw C.M., Szabadi E. Failure of central 5-hydroxytryptamine depletion to alter the effect of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) on timing performance on the free-operant psychophysical procedure. Psychopharmacology (Berl) 2001, 158:305-313.
24. 2 receptor agonist, DOI (2,5-dimethoxy-4-iodoamphetamine), and antagonist, ketanserin, on the performance on a free-operant timing schedule. Behav. Pharmacol. 2003, 14:599-607.
25. 2A receptors. Psychopharmacology (Berl) 2004, 176:154-165.
26. Body S., Kheramin S., Mobini S., Ho M.-Y., Velazquez-Martinez D.N., Bradshaw C.M., Szabadi E. Antagonism by WAY-100635 of the effects of 8-OH-DPAT on performance on a free-operant timing schedule in intact and 5-HT-depleted rats. Behav. Pharmacol. 2002, 13:603-614.
27. 2A/2C receptor mechanism as shown by ketanserin: 24-h follow-up studies. Prog. Neuro-Psychopharm. Biol. Psychol. 2004, 28:547-557.
28. Bueti D. The sensory representation of time. Front. Integr. Neurosci. 2011, 5:37-39.
29. Buhusi C.V. Dopaminergic mechanisms of interval timing and attention. Functional and Neural Mechanisms of Interval Timing 2003, 317-338. CRC Press, Boca Raton. W.H. Meck (Ed.).
30. Buhusi C.V., Meck W.H. What makes us tick? Functional and neural mechanisms of interval timing. Nat. Rev. Neurosci. 2005, 6:755-765.
31. Cardinal R.N., Pennicott D.R., Sugathapala C.L., Robbins T.W., Everitt B.J. Impulsive choice induced in rats by lesions of the nucleus accumbens core. Science 2001, 292:2499-2501.
32. Catania A.C., Reynolds G.S. A quantitative analysis of the responding maintained by interval schedules of reinforcement. J. Exp. Anal. Behav. 1968, 11(Suppl.):327-383.
33. Cheng R.K., Hakak O., Meck W.H. Habit formation and the loss of control of an internal clock: inverse relationship between the level of baseline training and the clock-speed enhancing effects of methamphetamine. Psychopharmacology (Berl) 2007, 193:351-362.
34. 1 dopamine receptors. Psychopharmacology (Berl) 2007, 195:213-222.
35. 1 dopamine receptors in d-amphetamine's effect on timing behaviour in the free-operant psychophysical procedure. Psychopharmacology (Berl) 2006, 185:378-388.
36. Cheung T.H.C., Bezzina G., Body S., Fone K.C.F., Bradshaw C.M., Szabadi E. Tolerance to the effect of 2,5-dimethoxy-4-iodoamphetamine (DOI) on free-operant timing behaviour: interaction between behavioural and pharmacological mechanisms. Psychopharmacology (Berl) 2007, 192:521-535.
37. 2 dopamine receptors. Psychopharmacology (Berl) 2007, 193:423-436.
38. Chiang T.-J., Al-Ruwaitea A.S.A., Ho M.-Y., Bradshaw C.M., Szabadi E. The influence of 'switching' on the psychometric function in the free-operant psychophysical procedure. Behav. Processes 1998, 44:197-209.
39. Chiang T.-J., Al-Ruwaitea A.S.A., Ho M.-Y., Bradshaw C.M., Szabadi E. Effect of central 5-hydroxytryptamine depletion on performance on the free-operant psychophysical procedure: facilitation of switching, but no effect on temporal differentiation of responding. Psychopharmacology (Berl) 1999, 143:166-173.
40. Chiang T.-J., Al-Ruwaitea A.S.A., Mobini S., Ho M.-Y., Bradshaw C.M., Szabadi E. The effect of d-amphetamine on performance on two operant timing schedules. Psychopharmacology (Berl) 2000, 150:170-184.
41. Chiang T.-J., Al-Ruwaitea A.S.A., Mobini S., Ho M.-Y., Bradshaw C.M., Szabadi E. Effects of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) on performance on two operant timing schedules. Psychopharmacology (Berl) 2000, 151:379-391.
42. Coull J.T., Cheng R.K., Meck W.H. Neuroanatomical and neurochemical substrates of timing. Neuropsychopharmacology 2011, 36:3-25.
43. Cui X. Hyperbolic discounting emerges from the scalar property of interval timing. Front. Integr. Neurosci. 2011, 5:100-101.
44. da Costa Araújo S., Body S., Hampson C.L., Langley R.W., Deakin J.F.W., Anderson I.M., Bradshaw C.M., Szabadi E. Effects of lesions of the nucleus accumbens core on inter-temporal choice: further observations with an adjusting-delay procedure. Behav. Brain Res. 2009, 202:272-277.
45. da Costa Araújo S., Body S., Valencia-Torres L., Olarte-Sánchez C.M., Bak V.K., Deakin J.F.W., Anderson I.M., Bradshaw C.M., Szabadi E. Choice between reinforcer delays versus choice between reinforcer magnitudes: differential Fos expression in the orbital prefrontal cortex and nucleus accumbens core. Behav. Brain Res. 2010, 213:269-277.
46. 2B/2C receptor subtypes in the control of accumbal and striatal dopamine release elicited in vivo by dorsal raphe nucleus electrical stimulation. J. Neurochem. 1999, 73:1033-1042.
47. De Mei C., Ramos M., Iitaka C., Borrelli E. Getting specialized: presynaptic and postsynaptic dopamine D2 receptors. Curr. Opin. Pharmacol. 2009, 9:53-58.
48. Gerfen C.R. Basal ganglia. The Rat Nervous System 2004, 458-509. Elsevier, San Diego. 3rd ed. G. Paxinos (Ed.).
49. Gibbon J. Scalar expectancy theory and Weber's law in animal timing. Psychol. Rev. 1977, 84:279-325.
50. Gibbon J. Origins of scalar timing. Learn. Motiv. 1991, 22:3-38.
51. Gibbon J., Malapani C., Dale C.L., Gallistel C.R. Toward a neurobiology of temporal cognition: advances and challenges. Curr. Opin. Neurobiol. 1997, 7:170-184.
52. 2 receptor agonists. Eur. J. Pharmacol. 1994, 264:325-330.
53. Hampson C.L., Body S., den Boon F.S., Cheung T.H.C., Bezzina G., Langley R.W., Fone K.C.F., Bradshaw C.M., Szabadi E. Comparison of the effects of 2,5-dimethoxy-4-iodoamphetamine (DOI) and d-amphetamine on the ability of rats to discriminate the durations and intensities of light stimuli. Behav. Pharmacol. 2010, 21:11-20.
54. Hannon J., Hoyer D. Molecular biology of 5-HT receptors. Behav. Brain Res. 2008, 195:198-213.
55. Hayes D.J., Greenshaw A.J. 5-HT receptors and reward-related behaviour: a review. Neurosci. Biobehav. Rev. 2011, 35:1419-1449.
56. Herdegen T., Leah J.D. Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins. Brain Res. Rev. 1998, 28:370-490.
57. Higa J.J., Staddon J.E.R. Dynamic models of rapid temporal control in animals. Time and Behaviour: Psychological and Neurobehavioural Analyses 1997, 1-40. Elsevier, Amsterdam. C.M. Bradshaw, E. Szabadi (Eds.).
58. Ho M.-Y., Velazquez-Martinez D.N., Bradshaw C.M., Szabadi E. 5-Hydroxytryptamine and interval timing behaviour. Pharmacol. Biochem. Behav. 2002, 71:773-785.
59. Ho M.-Y., Al-Zahrani S.S.A., Al-Ruwaitea A.S.A., Bradshaw C.M., Szabadi E. 5-Hydroxytryptamine and impulse control: prospects for a behavioural analysis. J. Psychopharmacol. 1998, 12:68-78.
60. Ivry R.B., Richardson T.C. Temporal control and coordination: the multiple timer model. Brain Cogn. 2002, 48:117-132.
61. Jongen-Relo A.L., Feldon J. Specific neuronal protein: a new tool for histological evaluation of excitotoxic lesions. Physiol. Behav. 2002, 76:449-456.
62. 2A antagonist with a favourable CNS safety profile. J. Pharmacol. Exp. Ther. 1996, 277:968-981.
63. Killeen P.R., Fetterman J.G. A behavioral theory of timing. Psychol. Rev. 1988, 95:274-295.
64. Killeen P.R., Fetterman J.G., Bizo L.A. Time's causes. Time and Behaviour: Psychological and Neurobehavioural Analyses 1997, 79-131. Elsevier, Amsterdam. C.M. Bradshaw, E. Szabadi (Eds.).
65. Machado A., Guilhardi P. Shifts in the psychometric function and their implications for models of timing. J. Exp. Anal. Behav. 2000, 74:25-54.
66. Machado A., Malheiro M.T., Erlhagen W. Learning to time: a perspective. J. Exp. Anal. Behav. 2009, 92:423-458.
67. Matell M.S., Meck W.H. Neuropsychological mechanisms of interval timing behavior. Bioessays 2000, 22:94-103.
68. Matell M.S., Meck W.H. Cortico-striatal circuits and interval timing: coincidence detection of oscillatory processes. Cogn. Brain Res. 2004, 21:139-170.
69. Meck W.H. Affinity for the dopamine D2 receptor predicts neuroleptic potency in decreasing the speed of an internal clock. Pharmacol. Biochem. Behav. 1986, 25:1185-1189.
70. Meck W.H. Neuropharmacology of timing and time perception. Cogn. Brain Res. 1996, 3:227-242.
71. Meck W.H. Neuroanatomical localization of an internal clock: a functional link between mesolimbic, nigrostriatal, and mesocortical dopaminergic systems. Brain Res. 2006, 1109:93-107.
72. Mengod G., Cortes R., Vilaró M.T., Hoyer D. Distribution of 5-HT receptors in the central nervous system. Handbook of the Behavioral Neurobiology of Serotonin 2010, 123-138. Elsevier, London. C.P. Müller, B.L. Jacobs (Eds.).
73. Missale C., Nash S.R., Robinson S.W., Jaber M., Caron M.G. Dopamine receptors: from structure to function. Physiol. Rev. 1998, 78:189-225.
74. Munoz A., Lopez-Real A., Labandeira-Garcia J.L., Guerra M.J. Interaction between the noradrenergic and serotonergic systems in locomotor hyperactivity and striatal expression of Fos induced by amphetamine in rats. Exp. Brain Res. 2003, 153:92-99.
75. Odum A.L., Lieving L.M., Schaai D.W. Effects of D-amphetamine in a temporal discrimination procedure: selective changes in timing or rate dependency?. J. Exp. Anal. Behav. 2002, 78:195-214.
76. Orduña V., García A., Bouzas A. Evaluation of rate-dependency and internal clock effects of D-amphetamine. Behav. Processes 2012, 90:428-432.
77. Olarte-Sánchez C.M., Valencia-Torres L., Body S., Cassaday H.J., Bradshaw C.M., Szabadi E. Effect of orexin-B-saporin induced lesions of the lateral hypothalamus on performance on a progressive-ratio schedule. J. Psychopharmacol. 2012, 26:871-886.
78. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates 2005, Elsevier, Oxford. fifth ed.
79. Pehek E.A., McFarlane H.G., Magaschak K., Price B., Pluto C.P. M100,907, a selective 5-HT2A antagonist, attenuates dopamine release in the rat medial prefrontal cortex. Brain Res. 2001, 888:51-59.
80. 2C/2B receptor subtypes modulate dopamine release induced in vivo by amphetamine and morphine in both the rat nucleus accumbens and striatum. Neuropsychopharmacology 2002, 26:311-324.
81. Pothuizen H.H.J., Jongen-Relo A.L., Feldon J., Yee B.K. Double dissociation of the effects of selective nucleus accumbens core and shell lesions on impulsive-choice behaviour and salience learning in rats. Eur. J. Neurosci. 2005, 22:2605-2616.
82. Pytliak M., Vargová V., Mechírová V., FelŠöci M. Serotonin receptors: from molecular biology to clinical applications. Physiol. Res. 2011, 60:15-25.
83. Raiteri M., Bertollini A., Angelini F., Levi G. d-Amphetamine as a releaser or reuptake inhibitor of biogenic amines in synaptosomes. Eur. J. Pharmacol. 1975, 34:189-195.
84. Rothman R.B., Baumann M.H., Dersch C.M., Romero D.V., Rice K.C., Carroll F.I., Partilla J.S. Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin. Synapse 2001, 36:32-41.
85. 2 receptors exert a state-dependent regulation of dopaminergic function: studies with MDL 100907 and the amphetamine analogue, 3,4-methylenedioxymethamphetamine. Eur. J. Pharmacol. 1992, 223:65-74.
86. Sershen H., Hashim A., Lajtha A. Serotonin-mediated dopamine release involves the dopamine uptake site and the serotonin receptor. Brain Res. Bull. 2000, 53:353-357.
87. Simen P., Balci F., deSouza L., Cohen J., Holmes P. A model of interval timing by neural integration. J. Neurosci. 2011, 31:9238-9253.
88. Staddon J.E.R., Higa J.J. Time and memory: towards a pacemaker-free theory of interval timing. J. Exp. Anal. Behav. 1999, 71:215-251.
89. Stubbs D.A. Scaling of stimulus durations by pigeons. J. Exp. Anal. Behav. 1976, 26:15-25.
90. Stubbs D.A. Temporal discrimination and a free-operant psychophysical procedure. J. Exp. Anal. Behav. 1980, 33:167-185.
91. Valencia-Torres L., Olarte-Sánchez C.M., Body S., Cheung T.H.C., Fone K.C.F., Bradshaw C.M., Szabadi E. Fos expression in the prefrontal cortex and ventral striatum after exposure to a free-operant timing schedule. Behav. Brain Res. 2012, 235:273-279.
92. Valencia-Torres L., Olarte-Sánchez C.M., Body S., Fone K.C.F., Bradshaw C.M., Szabadi E. Fos expression in the prefrontal cortex and nucleus accumbens following exposure to retrospective timing tasks. Behav. Neurosci. 2011, 125:202-214.
93. Valencia-Torres L., Olarte-Sánchez C.M., Body S., Fone K.C.F., Bradshaw C.M., Szabadi E. Fos expression in the orbital prefrontal cortex after exposure to the fixed-interval peak procedure. Behav. Brain Res. 2012, 229:372-377.
94. Valencia-Torres L., Olarte-Sánchez C.M., da Costa Araújo S., Body S., Bradshaw C.M., Szabadi E. Nucleus accumbens and delay discounting in rats: evidence from a new quantitative protocol for analysing inter-temporal choice. Psychopharmacology (Berl) 2012, 219:271-283.
95. van den Heuvel D.M., Pasterkamp R.J. Getting connected in the dopamine system. Prog. Neurobiol. 2008, 85:75-93.
96. Wiener M., Lohoff F.W., Coslett H.B. Double dissociation of dopamine genes and timing in humans. J. Cogn. Neurosci. 2011, 23:2811-2821.
97. Wiener M., Matell M.S., Coslett H.B. Multiple mechanisms for temporal processing. Front. Integr. Neurosci. 2011, 5:472-473.
98. Wiener M., Turkeltaub P.E., Coslett H.B. The image of time: a voxel-wise meta-analysis. Neuroimage 2010, 49:1728-1740.
99. Witmann M., Paulus M.P. Decision making, impulsivity and time perception. Trends Cogn. Sci. 2008, 12:7-12.
100. Wittmann M., Lovero K.L., Lane S.D., Paulus M.P. Now or later? Striatum and insula activation to immediate versus delayed rewards. J. Neurosci. Psychol. Econ. 2010, 3:15-26.
101. Ziance R.J. Specificity of amphetamine induced release of norepinephrine and serotonin from rat brain in vitro. Res. Commun. Chem. Pathol. Pharmacol. 1977, 18:627-644.