-
1
-
-
84856720655
-
USE1 is a bispecific conjugating enzyme for ubiquitin and FAT10, which FAT10ylates itself in cis
-
Aichem A., Pelzer C., Lukasiak S., Kalveram B., Sheppard P.W., Rani N., Schmidtke G., Groettrup M. USE1 is a bispecific conjugating enzyme for ubiquitin and FAT10, which FAT10ylates itself in cis. Nat. Commun. 2010, 1:1-10.
-
(2010)
Nat. Commun.
, vol.1
, pp. 1-10
-
-
Aichem, A.1
Pelzer, C.2
Lukasiak, S.3
Kalveram, B.4
Sheppard, P.W.5
Rani, N.6
Schmidtke, G.7
Groettrup, M.8
-
2
-
-
57649165427
-
Regulation of postsynaptic RapGAP SPAR by Polo-like kinase 2 and the SCFbeta-TRCP ubiquitin ligase in hippocampal neurons
-
Ang X.L., Seeburg D.P., Sheng M., Harper J.W. Regulation of postsynaptic RapGAP SPAR by Polo-like kinase 2 and the SCFbeta-TRCP ubiquitin ligase in hippocampal neurons. J. Biol. Chem. 2008, 283:29424-29432.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 29424-29432
-
-
Ang, X.L.1
Seeburg, D.P.2
Sheng, M.3
Harper, J.W.4
-
3
-
-
33745593049
-
Activity-dependent dynamics and sequestration of proteasomes in dendritic spines
-
Bingol B., Schuman E.M. Activity-dependent dynamics and sequestration of proteasomes in dendritic spines. Nature 2006, 441:1144-1148.
-
(2006)
Nature
, vol.441
, pp. 1144-1148
-
-
Bingol, B.1
Schuman, E.M.2
-
4
-
-
78650962524
-
Deconstruction for reconstruction: the role of proteolysis in neural plasticity and disease
-
Bingol B., Sheng M. Deconstruction for reconstruction: the role of proteolysis in neural plasticity and disease. Neuron 2011, 69:22-32.
-
(2011)
Neuron
, vol.69
, pp. 22-32
-
-
Bingol, B.1
Sheng, M.2
-
5
-
-
70649088959
-
Ablation of arginylation in the mouse N-end rule pathway: loss of fat, higher metabolic rate, damaged spermatogenesis, and neurological perturbations
-
Brower C.S., Varshavsky A. Ablation of arginylation in the mouse N-end rule pathway: loss of fat, higher metabolic rate, damaged spermatogenesis, and neurological perturbations. PLoS ONE 2009, 4:e7757. 10.1371/journal.pone.0007757.
-
(2009)
PLoS ONE
, vol.4
-
-
Brower, C.S.1
Varshavsky, A.2
-
6
-
-
33745456782
-
FAT10/diubiquitin-like protein-deficient mice exhibit minimal phenotypic differences
-
Canaan A., Yu X., Booth C.J., Lian J., Lazar I., Gamfi S.L., Castille K., Kohya N., Nakayama Y., Liu Y.C., et al. FAT10/diubiquitin-like protein-deficient mice exhibit minimal phenotypic differences. Mol. Cell. Biol. 2006, 26:5180-5189.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 5180-5189
-
-
Canaan, A.1
Yu, X.2
Booth, C.J.3
Lian, J.4
Lazar, I.5
Gamfi, S.L.6
Castille, K.7
Kohya, N.8
Nakayama, Y.9
Liu, Y.C.10
-
7
-
-
34748884321
-
E1-L2 activates both ubiquitin and FAT10
-
Chiu Y.H., Sun Q., Chen Z.J. E1-L2 activates both ubiquitin and FAT10. Mol. Cell 2007, 27:1014-1023.
-
(2007)
Mol. Cell
, vol.27
, pp. 1014-1023
-
-
Chiu, Y.H.1
Sun, Q.2
Chen, Z.J.3
-
8
-
-
33750506086
-
Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking
-
Chowdhury S., Shepherd J.D., Okuno H., Lyford G., Petralia R.S., Plath N., Kuhl D., Huganir R.L., Worley P.F. Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking. Neuron 2006, 52:445-459.
-
(2006)
Neuron
, vol.52
, pp. 445-459
-
-
Chowdhury, S.1
Shepherd, J.D.2
Okuno, H.3
Lyford, G.4
Petralia, R.S.5
Plath, N.6
Kuhl, D.7
Huganir, R.L.8
Worley, P.F.9
-
9
-
-
4644295494
-
Biochemical analysis of Angelman syndrome-associated mutations in the E3 ubiquitin ligase E6-associated protein
-
Cooper E.M., Hudson A.W., Amos J., Wagstaff J., Howley P.M. Biochemical analysis of Angelman syndrome-associated mutations in the E3 ubiquitin ligase E6-associated protein. J. Biol. Chem. 2004, 279:41208-41217.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 41208-41217
-
-
Cooper, E.M.1
Hudson, A.W.2
Amos, J.3
Wagstaff, J.4
Howley, P.M.5
-
10
-
-
0035137947
-
The amygdala: vigilance and emotion
-
Davis M., Whalen P.J. The amygdala: vigilance and emotion. Mol. Psychiatry 2001, 6:13-34.
-
(2001)
Mol. Psychiatry
, vol.6
, pp. 13-34
-
-
Davis, M.1
Whalen, P.J.2
-
11
-
-
37549057995
-
The Angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal deficiency results in abnormal dendritic spine morphology
-
Dindot S.V., Antalffy B.A., Bhattacharjee M.B., Beaudet A.L. The Angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal deficiency results in abnormal dendritic spine morphology. Hum. Mol. Genet. 2008, 17:111-118.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 111-118
-
-
Dindot, S.V.1
Antalffy, B.A.2
Bhattacharjee, M.B.3
Beaudet, A.L.4
-
12
-
-
34247158646
-
Ubiquitination and degradation of the anti-apoptotic protein ARC by MDM2
-
Foo R.S., Chan L.K., Kitsis R.N., Bennett M.R. Ubiquitination and degradation of the anti-apoptotic protein ARC by MDM2. J. Biol. Chem. 2007, 282:5529-5535.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 5529-5535
-
-
Foo, R.S.1
Chan, L.K.2
Kitsis, R.N.3
Bennett, M.R.4
-
13
-
-
67349182343
-
Autism genome-wide copy number variation reveals ubiquitin and neuronal genes
-
Glessner J.T., Wang K., Cai G., Korvatska O., Kim C.E., Wood S., Zhang H., Estes A., Brune C.W., Bradfield J.P., et al. Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. Nature 2009, 459:569-573.
-
(2009)
Nature
, vol.459
, pp. 569-573
-
-
Glessner, J.T.1
Wang, K.2
Cai, G.3
Korvatska, O.4
Kim, C.E.5
Wood, S.6
Zhang, H.7
Estes, A.8
Brune, C.W.9
Bradfield, J.P.10
-
14
-
-
77649083119
-
The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc
-
Greer P.L., Hanayama R., Bloodgood B.L., Mardinly A.R., Lipton D.M., Flavell S.W., Kim T.K., Griffith E.C., Waldon Z., Maehr R., et al. The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc. Cell 2010, 140:704-716.
-
(2010)
Cell
, vol.140
, pp. 704-716
-
-
Greer, P.L.1
Hanayama, R.2
Bloodgood, B.L.3
Mardinly, A.R.4
Lipton, D.M.5
Flavell, S.W.6
Kim, T.K.7
Griffith, E.C.8
Waldon, Z.9
Maehr, R.10
-
15
-
-
77954416653
-
The ubiquitin-proteasome pathway and synaptic plasticity
-
Hegde A.N. The ubiquitin-proteasome pathway and synaptic plasticity. Learn. Mem. 2010, 17:314-327.
-
(2010)
Learn. Mem.
, vol.17
, pp. 314-327
-
-
Hegde, A.N.1
-
16
-
-
0032741446
-
Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade
-
Huang L., Kinnucan E., Wang G., Beaudenon S., Howley P.M., Huibregtse J.M., Pavletich N.P. Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade. Science 1999, 286:1321-1326.
-
(1999)
Science
, vol.286
, pp. 1321-1326
-
-
Huang, L.1
Kinnucan, E.2
Wang, G.3
Beaudenon, S.4
Howley, P.M.5
Huibregtse, J.M.6
Pavletich, N.P.7
-
17
-
-
0028907874
-
A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase
-
Huibregtse J.M., Scheffner M., Beaudenon S., Howley P.M. A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc. Natl. Acad. Sci. USA 1995, 92:2563-2567.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 2563-2567
-
-
Huibregtse, J.M.1
Scheffner, M.2
Beaudenon, S.3
Howley, P.M.4
-
18
-
-
78149460672
-
Degradation of postsynaptic scaffold GKAP and regulation of dendritic spine morphology by the TRIM3 ubiquitin ligase in rat hippocampal neurons
-
Hung A.Y., Sung C.C., Brito I.L., Sheng M. Degradation of postsynaptic scaffold GKAP and regulation of dendritic spine morphology by the TRIM3 ubiquitin ligase in rat hippocampal neurons. PLoS ONE 2010, 5:e9842. 10.1371/journal.pone.0009842.
-
(2010)
PLoS ONE
, vol.5
-
-
Hung, A.Y.1
Sung, C.C.2
Brito, I.L.3
Sheng, M.4
-
19
-
-
34347329214
-
Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging
-
Jin J., Li X., Gygi S.P., Harper J.W. Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging. Nature 2007, 447:1135-1138.
-
(2007)
Nature
, vol.447
, pp. 1135-1138
-
-
Jin, J.1
Li, X.2
Gygi, S.P.3
Harper, J.W.4
-
20
-
-
78650984262
-
The anaphase promoting complex is required for memory function in mice
-
Kuczera T., Stilling R.M., Hsia H.E., Bahari-Javan S., Irniger S., Nasmyth K., Sananbenesi F., Fischer A. The anaphase promoting complex is required for memory function in mice. Learn. Mem. 2011, 18:49-57.
-
(2011)
Learn. Mem.
, vol.18
, pp. 49-57
-
-
Kuczera, T.1
Stilling, R.M.2
Hsia, H.E.3
Bahari-Javan, S.4
Irniger, S.5
Nasmyth, K.6
Sananbenesi, F.7
Fischer, A.8
-
21
-
-
0030908874
-
Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity
-
Kumar S., Kao W.H., Howley P.M. Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity. J. Biol. Chem. 1997, 272:13548-13554.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13548-13554
-
-
Kumar, S.1
Kao, W.H.2
Howley, P.M.3
-
22
-
-
35848947251
-
Molecular mechanisms of schizophrenia. Cellular physiology and biochemistry. International Journal of Experimental Cellular Physiology
-
Lang U.E., Puls I., Muller D.J., Strutz-Seebohm N., Gallinat J. Molecular mechanisms of schizophrenia. Cellular physiology and biochemistry. International Journal of Experimental Cellular Physiology. Biochem. Pharmacol. 2007, 20:687-702.
-
(2007)
Biochem. Pharmacol.
, vol.20
, pp. 687-702
-
-
Lang, U.E.1
Puls, I.2
Muller, D.J.3
Strutz-Seebohm, N.4
Gallinat, J.5
-
23
-
-
79960693484
-
Alternative ubiquitin activation/conjugation cascades interact with N-end rule ubiquitin ligases to control degradation of RGS proteins
-
Lee P.C., Sowa M.E., Gygi S.P., Harper J.W. Alternative ubiquitin activation/conjugation cascades interact with N-end rule ubiquitin ligases to control degradation of RGS proteins. Mol. Cell 2011, 43:392-405.
-
(2011)
Mol. Cell
, vol.43
, pp. 392-405
-
-
Lee, P.C.1
Sowa, M.E.2
Gygi, S.P.3
Harper, J.W.4
-
24
-
-
79958046350
-
An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning
-
Litterman N., Ikeuchi Y., Gallardo G., O'Connell B.C., Sowa M.E., Gygi S.P., Harper J.W., Bonni A. An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning. PLoS Biol. 2011, 9:e1001060. 10.1371/journal.pbio.1001060.
-
(2011)
PLoS Biol.
, vol.9
-
-
Litterman, N.1
Ikeuchi, Y.2
Gallardo, G.3
O'Connell, B.C.4
Sowa, M.E.5
Gygi, S.P.6
Harper, J.W.7
Bonni, A.8
-
25
-
-
78049395303
-
Ubiquitination in postsynaptic function and plasticity
-
Mabb A.M., Ehlers M.D. Ubiquitination in postsynaptic function and plasticity. Annu. Rev. Cell Dev. Biol. 2010, 26:179-210.
-
(2010)
Annu. Rev. Cell Dev. Biol.
, vol.26
, pp. 179-210
-
-
Mabb, A.M.1
Ehlers, M.D.2
-
26
-
-
79957560791
-
Angelman syndrome: insights into genomic imprinting and neurodevelopmental phenotypes
-
Mabb A.M., Judson M.C., Zylka M.J., Philpot B.D. Angelman syndrome: insights into genomic imprinting and neurodevelopmental phenotypes. Trends Neurosci. 2011, 34:293-303.
-
(2011)
Trends Neurosci.
, vol.34
, pp. 293-303
-
-
Mabb, A.M.1
Judson, M.C.2
Zylka, M.J.3
Philpot, B.D.4
-
27
-
-
0344443828
-
Targeted protein degradation and synapse remodeling by an inducible protein kinase
-
Pak D.T., Sheng M. Targeted protein degradation and synapse remodeling by an inducible protein kinase. Science 2003, 302:1368-1373.
-
(2003)
Science
, vol.302
, pp. 1368-1373
-
-
Pak, D.T.1
Sheng, M.2
-
28
-
-
79955536349
-
Shank3 mutant mice display autistic-like behaviours and striatal dysfunction
-
Peça J., Feliciano C., Ting J.T., Wang W., Wells M.F., Venkatraman T.N., Lascola C.D., Fu Z., Feng G. Shank3 mutant mice display autistic-like behaviours and striatal dysfunction. Nature 2011, 472:437-442.
-
(2011)
Nature
, vol.472
, pp. 437-442
-
-
Peça, J.1
Feliciano, C.2
Ting, J.T.3
Wang, W.4
Wells, M.F.5
Venkatraman, T.N.6
Lascola, C.D.7
Fu, Z.8
Feng, G.9
-
29
-
-
34548188010
-
UBE1L2, a novel E1 enzyme specific for ubiquitin
-
Pelzer C., Kassner I., Matentzoglu K., Singh R.K., Wollscheid H.P., Scheffner M., Schmidtke G., Groettrup M. UBE1L2, a novel E1 enzyme specific for ubiquitin. J. Biol. Chem. 2007, 282:23010-23014.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 23010-23014
-
-
Pelzer, C.1
Kassner, I.2
Matentzoglu, K.3
Singh, R.K.4
Wollscheid, H.P.5
Scheffner, M.6
Schmidtke, G.7
Groettrup, M.8
-
30
-
-
33750513623
-
Increased expression of the immediate-early gene arc/arg3.1 reduces AMPA receptor-mediated synaptic transmission
-
Rial Verde E.M., Lee-Osbourne J., Worley P.F., Malinow R., Cline H.T. Increased expression of the immediate-early gene arc/arg3.1 reduces AMPA receptor-mediated synaptic transmission. Neuron 2006, 52:461-474.
-
(2006)
Neuron
, vol.52
, pp. 461-474
-
-
Rial Verde, E.M.1
Lee-Osbourne, J.2
Worley, P.F.3
Malinow, R.4
Cline, H.T.5
-
31
-
-
0027358723
-
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
-
Scheffner M., Huibregtse J.M., Vierstra R.D., Howley P.M. The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 1993, 75:495-505.
-
(1993)
Cell
, vol.75
, pp. 495-505
-
-
Scheffner, M.1
Huibregtse, J.M.2
Vierstra, R.D.3
Howley, P.M.4
-
32
-
-
67349256160
-
Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways
-
Schulman B.A., Harper J.W. Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways. Nat. Rev. Mol. Cell Biol. 2009, 10:319-331.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 319-331
-
-
Schulman, B.A.1
Harper, J.W.2
-
33
-
-
33750503402
-
Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors
-
Shepherd J.D., Rumbaugh G., Wu J., Chowdhury S., Plath N., Kuhl D., Huganir R.L., Worley P.F. Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors. Neuron 2006, 52:475-484.
-
(2006)
Neuron
, vol.52
, pp. 475-484
-
-
Shepherd, J.D.1
Rumbaugh, G.2
Wu, J.3
Chowdhury, S.4
Plath, N.5
Kuhl, D.6
Huganir, R.L.7
Worley, P.F.8
-
34
-
-
77953800799
-
Behavioural phenotyping assays for mouse models of autism
-
Silverman J.L., Yang M., Lord C., Crawley J.N. Behavioural phenotyping assays for mouse models of autism. Nat. Rev. Neurosci. 2010, 11:490-502.
-
(2010)
Nat. Rev. Neurosci.
, vol.11
, pp. 490-502
-
-
Silverman, J.L.1
Yang, M.2
Lord, C.3
Crawley, J.N.4
-
35
-
-
80053626726
-
Increased gene dosage of Ube3a results in autism traits and decreased glutamate synaptic transmission in mice
-
103ra197
-
Smith S.E., Zhou Y.D., Zhang G., Jin Z., Stoppel D.C., Anderson M.P. Increased gene dosage of Ube3a results in autism traits and decreased glutamate synaptic transmission in mice. Sci. Transl. Med. 2011, 3. 103ra197. 10.1126/scitranslmed.3002627.
-
(2011)
Sci. Transl. Med.
, vol.3
-
-
Smith, S.E.1
Zhou, Y.D.2
Zhang, G.3
Jin, Z.4
Stoppel, D.C.5
Anderson, M.P.6
-
36
-
-
0013865890
-
Habituation: a model phenomenon for the study of neuronal substrates of behavior
-
Thompson R.F., Spencer W.A. Habituation: a model phenomenon for the study of neuronal substrates of behavior. Psychol. Rev. 1966, 73:16-43.
-
(1966)
Psychol. Rev.
, vol.73
, pp. 16-43
-
-
Thompson, R.F.1
Spencer, W.A.2
-
37
-
-
0030460425
-
Subregion- and cell type-restricted gene knockout in mouse brain
-
Tsien J.Z., Chen D.F., Gerber D., Tom C., Mercer E.H., Anderson D.J., Mayford M., Kandel E.R., Tonegawa S. Subregion- and cell type-restricted gene knockout in mouse brain. Cell 1996, 87:1317-1326.
-
(1996)
Cell
, vol.87
, pp. 1317-1326
-
-
Tsien, J.Z.1
Chen, D.F.2
Gerber, D.3
Tom, C.4
Mercer, E.H.5
Anderson, D.J.6
Mayford, M.7
Kandel, E.R.8
Tonegawa, S.9
-
38
-
-
69249150517
-
A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system
-
van Wijk S.J., de Vries S.J., Kemmeren P., Huang A., Boelens R., Bonvin A.M., Timmers H.T. A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system. Mol. Syst. Biol. 2009, 5:295.
-
(2009)
Mol. Syst. Biol.
, vol.5
, pp. 295
-
-
van Wijk, S.J.1
de Vries, S.J.2
Kemmeren, P.3
Huang, A.4
Boelens, R.5
Bonvin, A.M.6
Timmers, H.T.7
-
39
-
-
76749162906
-
The dynamic ubiquitin ligase duo: Cdh1-APC and Cdc20-APC regulate neuronal morphogenesis and connectivity
-
Yang Y., Kim A.H., Bonni A. The dynamic ubiquitin ligase duo: Cdh1-APC and Cdc20-APC regulate neuronal morphogenesis and connectivity. Curr. Opin. Neurobiol. 2010, 20:92-99.
-
(2010)
Curr. Opin. Neurobiol.
, vol.20
, pp. 92-99
-
-
Yang, Y.1
Kim, A.H.2
Bonni, A.3
-
40
-
-
67349178189
-
Ube3a is required for experience-dependent maturation of the neocortex
-
Yashiro K., Riday T.T., Condon K.H., Roberts A.C., Bernardo D.R., Prakash R., Weinberg R.J., Ehlers M.D., Philpot B.D. Ube3a is required for experience-dependent maturation of the neocortex. Nat. Neurosci. 2009, 12:777-783.
-
(2009)
Nat. Neurosci.
, vol.12
, pp. 777-783
-
-
Yashiro, K.1
Riday, T.T.2
Condon, K.H.3
Roberts, A.C.4
Bernardo, D.R.5
Prakash, R.6
Weinberg, R.J.7
Ehlers, M.D.8
Philpot, B.D.9
-
41
-
-
70350461507
-
Building ubiquitin chains: E2 enzymes at work
-
Ye Y., Rape M. Building ubiquitin chains: E2 enzymes at work. Nat. Rev. Mol. Cell Biol. 2009, 10:755-764.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 755-764
-
-
Ye, Y.1
Rape, M.2
-
42
-
-
28444458475
-
Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome)
-
Zenker M., Mayerle J., Lerch M.M., Tagariello A., Zerres K., Durie P.R., Beier M., Hülskamp G., Guzman C., Rehder H., et al. Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome). Nat. Genet. 2005, 37:1345-1350.
-
(2005)
Nat. Genet.
, vol.37
, pp. 1345-1350
-
-
Zenker, M.1
Mayerle, J.2
Lerch, M.M.3
Tagariello, A.4
Zerres, K.5
Durie, P.R.6
Beier, M.7
Hülskamp, G.8
Guzman, C.9
Rehder, H.10
|