메뉴 건너뛰기




Volumn 110, Issue 17, 2013, Pages 7009-7013

Sphingosine-1-phosphate-mediated osteoclast precursor monocyte migration is a critical point of control in antibone-resorptive action of active vitamin D

Author keywords

Chemotaxis; Circulation; Imaging; Immunology; Treatment

Indexed keywords

CALCITRIOL; ELDECALCITOL; SPHINGOSINE 1 PHOSPHATE;

EID: 84876864069     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1218799110     Document Type: Article
Times cited : (113)

References (39)
  • 1
    • 0034284970 scopus 로고    scopus 로고
    • Bone resorption by osteoclasts
    • Teitelbaum SL (2000) Bone resorption by osteoclasts. Science 289(5484):1504-1508.
    • (2000) Science , vol.289 , Issue.5484 , pp. 1504-1508
    • Teitelbaum, S.L.1
  • 2
    • 0043267732 scopus 로고    scopus 로고
    • Genetic regulation of osteoclast development and function
    • Teitelbaum SL, Ross FP (2003) Genetic regulation of osteoclast development and function. Nat Rev Genet 4(8):638-649.
    • (2003) Nat Rev Genet , vol.4 , Issue.8 , pp. 638-649
    • Teitelbaum, S.L.1    Ross, F.P.2
  • 3
    • 0036225281 scopus 로고    scopus 로고
    • Reaching a genetic and molecular understanding of skeletal development
    • Karsenty G, Wagner EF (2002) Reaching a genetic and molecular understanding of skeletal development. Dev Cell 2(4):389-406.
    • (2002) Dev Cell , vol.2 , Issue.4 , pp. 389-406
    • Karsenty, G.1    Wagner, E.F.2
  • 4
    • 63649143900 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis
    • Ishii M, et al. (2009) Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis. Nature 458(7237):524-528.
    • (2009) Nature , vol.458 , Issue.7237 , pp. 524-528
    • Ishii, M.1
  • 5
    • 70249085550 scopus 로고    scopus 로고
    • Quantifying cellular interaction dynamics in 3D fluorescence microscopy data
    • Klauschen F, et al. (2009) Quantifying cellular interaction dynamics in 3D fluorescence microscopy data. Nat Protoc 4(9):1305-1311.
    • (2009) Nat Protoc , vol.4 , Issue.9 , pp. 1305-1311
    • Klauschen, F.1
  • 6
    • 78650413566 scopus 로고    scopus 로고
    • Chemo-repulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo
    • Ishii M, Kikuta J, Shimazu Y, Meier-Schellersheim M, Germain RN (2010) Chemo-repulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo. J Exp Med 207(13):2793-2798.
    • (2010) J Exp Med , vol.207 , Issue.13 , pp. 2793-2798
    • Ishii, M.1    Kikuta, J.2    Shimazu, Y.3    Meier-Schellersheim, M.4    Germain, R.N.5
  • 7
    • 0034462185 scopus 로고    scopus 로고
    • Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3
    • Okamoto H, et al. (2000) Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3. Mol Cell Biol 20(24):9247-9261.
    • (2000) Mol Cell Biol , vol.20 , Issue.24 , pp. 9247-9261
    • Okamoto, H.1
  • 8
    • 36549072502 scopus 로고    scopus 로고
    • Bisphosphonates: An update on mechanisms of action and how these relate to clinical efficacy
    • Russell RG, et al. (2007) Bisphosphonates: An update on mechanisms of action and how these relate to clinical efficacy. Ann N Y Acad Sci 1117:209-257.
    • (2007) Ann N y Acad Sci , vol.1117 , pp. 209-257
    • Russell, R.G.1
  • 9
    • 77953510486 scopus 로고    scopus 로고
    • Odanacatib, a cathepsin-K inhibitor for osteoporosis: A two-year study in postmenopausal women with low bone density
    • Bone HG, et al. (2010) Odanacatib, a cathepsin-K inhibitor for osteoporosis: A two-year study in postmenopausal women with low bone density. J Bone Miner Res 25(5):937-947.
    • (2010) J Bone Miner Res , vol.25 , Issue.5 , pp. 937-947
    • Bone, H.G.1
  • 10
    • 78049522060 scopus 로고    scopus 로고
    • Odanacatib in the treatment of postmenopausal women with low bone mineral density: Three-year continued therapy and resolution of effect
    • Eisman JA, et al. (2011) Odanacatib in the treatment of postmenopausal women with low bone mineral density: Three-year continued therapy and resolution of effect. J Bone Miner Res 26(2):242-251.
    • (2011) J Bone Miner Res , vol.26 , Issue.2 , pp. 242-251
    • Eisman, J.A.1
  • 11
    • 0028988403 scopus 로고
    • Structure-function relationships in the vitamin D endocrine system
    • Bouillon R, Okamura WH, Norman AW (1995) Structure-function relationships in the vitamin D endocrine system. Endocr Rev 16(2):200-257.
    • (1995) Endocr Rev , vol.16 , Issue.2 , pp. 200-257
    • Bouillon, R.1    Okamura, W.H.2    Norman, A.W.3
  • 12
    • 78649697894 scopus 로고    scopus 로고
    • Vitamin D, disease and therapeutic opportunities
    • Plum LA, DeLuca HF (2010) Vitamin D, disease and therapeutic opportunities. Nat Rev Drug Discov 9(12):941-955.
    • (2010) Nat Rev Drug Discov , vol.9 , Issue.12 , pp. 941-955
    • Plum, L.A.1    Deluca, H.F.2
  • 13
    • 0001654980 scopus 로고
    • 1, 25-Dihy-droxyvitamin D3 causes formation of multinucleated cells with several osteoclast characteristics in cultures of primate marrow
    • Roodman GD, Ibbotson KJ, MacDonald BR, Kuehl TJ, Mundy GR (1985) 1, 25-Dihy-droxyvitamin D3 causes formation of multinucleated cells with several osteoclast characteristics in cultures of primate marrow. Proc Natl Acad Sci USA 82(23): 8213-8217.
    • (1985) Proc Natl Acad Sci USA , vol.82 , Issue.23 , pp. 8213-8217
    • Roodman, G.D.1    Ibbotson, K.J.2    MacDonald, B.R.3    Kuehl, T.J.4    Mundy, G.R.5
  • 14
    • 0032584208 scopus 로고    scopus 로고
    • Osteoclast differentiation factor is a ligand for osteoprote-gerin/ osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
    • Yasuda H, et al. (1998) Osteoclast differentiation factor is a ligand for osteoprote-gerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci USA 95(7):3597-3602.
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.7 , pp. 3597-3602
    • Yasuda, H.1
  • 15
    • 0033304730 scopus 로고    scopus 로고
    • Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families
    • Suda T, et al. (1999) Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr Rev 20(3): 345-357.
    • (1999) Endocr Rev , vol.20 , Issue.3 , pp. 345-357
    • Suda, T.1
  • 17
    • 84861572206 scopus 로고    scopus 로고
    • Bone effects of vitamin D-Discrepancies between in vivo and in vitro studies
    • Suda T, Takahashi F, Takahashi N (2012) Bone effects of vitamin D-Discrepancies between in vivo and in vitro studies. Arch Biochem Biophys 523(1):22-29.
    • (2012) Arch Biochem Biophys , vol.523 , Issue.1 , pp. 22-29
    • Suda, T.1    Takahashi, F.2    Takahashi, N.3
  • 18
    • 33646863511 scopus 로고    scopus 로고
    • RANKL-induced expression of tetraspanin CD9 in lipid raft membrane microdomain is essential for cell fusion during osteoclastogenesis
    • Ishii M, et al. (2006) RANKL-induced expression of tetraspanin CD9 in lipid raft membrane microdomain is essential for cell fusion during osteoclastogenesis. J Bone Miner Res 21(6):965-976.
    • (2006) J Bone Miner Res , vol.21 , Issue.6 , pp. 965-976
    • Ishii, M.1
  • 19
    • 77954022674 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate receptor type 1 regulates egress of mature T cells from mouse bone marrow
    • Maeda Y, Seki N, Sato N, Sugahara K, Chiba K (2010) Sphingosine 1-phosphate receptor type 1 regulates egress of mature T cells from mouse bone marrow. Int Immunol 22(6):515-525.
    • (2010) Int Immunol , vol.22 , Issue.6 , pp. 515-525
    • Maeda, Y.1    Seki, N.2    Sato, N.3    Sugahara, K.4    Chiba, K.5
  • 20
    • 1642465552 scopus 로고    scopus 로고
    • Conditional macrophage ablation in transgenic mice expressing a Fas-based suicide gene
    • Burnett SH, et al. (2004) Conditional macrophage ablation in transgenic mice expressing a Fas-based suicide gene. J Leukoc Biol 75(4):612-623.
    • (2004) J Leukoc Biol , vol.75 , Issue.4 , pp. 612-623
    • Burnett, S.H.1
  • 21
    • 0034028817 scopus 로고    scopus 로고
    • Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion
    • Jung S, et al. (2000) Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol Cell Biol 20(11): 4106-4114.
    • (2000) Mol Cell Biol , vol.20 , Issue.11 , pp. 4106-4114
    • Jung, S.1
  • 22
    • 76249099065 scopus 로고    scopus 로고
    • Role of CX3CL1/fractalkine in osteoclast differentiation and bone resorption
    • Koizumi K, et al. (2009) Role of CX3CL1/fractalkine in osteoclast differentiation and bone resorption. J Immunol 183(12):7825-7831.
    • (2009) J Immunol , vol.183 , Issue.12 , pp. 7825-7831
    • Koizumi, K.1
  • 23
    • 32444433446 scopus 로고    scopus 로고
    • C-Fos protein as a target of anti-osteoclastogenic action of vitamin D, and synthesis of new analogs
    • Takasu H, et al. (2006) c-Fos protein as a target of anti- osteoclastogenic action of vitamin D, and synthesis of new analogs. J Clin Invest 116(2):528-535.
    • (2006) J Clin Invest , vol.116 , Issue.2 , pp. 528-535
    • Takasu, H.1
  • 24
    • 84856200641 scopus 로고    scopus 로고
    • Daily administration of eldecalcitol (ED-71), an active vitamin D analog, increases bone mineral density by suppressing RANKL expression in mouse trabecular bone
    • Harada S, et al. (2012) Daily administration of eldecalcitol (ED-71), an active vitamin D analog, increases bone mineral density by suppressing RANKL expression in mouse trabecular bone. J Bone Miner Res 27(2):461-473.
    • (2012) J Bone Miner Res , vol.27 , Issue.2 , pp. 461-473
    • Harada, S.1
  • 25
    • 84857988635 scopus 로고    scopus 로고
    • Combination therapy with eldecalcitol and alendronate has therapeutic advantages over monotherapy by improving bone strength
    • Sakai S, Endo K, Takeda S, Mihara M, Shiraishi A (2012) Combination therapy with eldecalcitol and alendronate has therapeutic advantages over monotherapy by improving bone strength. Bone 50(5):1054-1063.
    • (2012) Bone , vol.50 , Issue.5 , pp. 1054-1063
    • Sakai, S.1    Endo, K.2    Takeda, S.3    Mihara, M.4    Shiraishi, A.5
  • 26
    • 84867622282 scopus 로고    scopus 로고
    • Effects of combined treatment with eldecalcitol and alendronate on bone mass, mechanical properties, and bone histo-morphometry in ovariectomized rats: A comparison with alfacalcidol and alendro-nate
    • Sugimoto M, Futaki N, Harada M, Kaku S (2013) Effects of combined treatment with eldecalcitol and alendronate on bone mass, mechanical properties, and bone histo-morphometry in ovariectomized rats: A comparison with alfacalcidol and alendro-nate. Bone 52(1):181-188.
    • (2013) Bone , vol.52 , Issue.1 , pp. 181-188
    • Sugimoto, M.1    Futaki, N.2    Harada, M.3    Kaku, S.4
  • 27
    • 33847138963 scopus 로고    scopus 로고
    • Superiority of a combined treatment of Alendronate and Alfacalcidol compared to the combination of Alendronate and plain vitamin D or Alfacalcidol alone in established postmenopausal or male osteoporosis (AAC-Trial)
    • Ringe JD, Farahmand P, Schacht E, Rozehnal A (2007) Superiority of a combined treatment of Alendronate and Alfacalcidol compared to the combination of Alendronate and plain vitamin D or Alfacalcidol alone in established postmenopausal or male osteoporosis (AAC-Trial). Rheumatol Int 27(5):425-434.
    • (2007) Rheumatol Int , vol.27 , Issue.5 , pp. 425-434
    • Ringe, J.D.1    Farahmand, P.2    Schacht, E.3    Rozehnal, A.4
  • 28
    • 24344474407 scopus 로고    scopus 로고
    • A new active vitamin D, ED-71, increases bone mass in osteoporotic patients under vitamin D supplementation: A randomized, double-blind, placebo-controlled clinical trial
    • Matsumoto T, et al. (2005) A new active vitamin D, ED-71, increases bone mass in osteoporotic patients under vitamin D supplementation: A randomized, double-blind, placebo-controlled clinical trial. J Clin Endocrinol Metab 90(9):5031-5036.
    • (2005) J Clin Endocrinol Metab , vol.90 , Issue.9 , pp. 5031-5036
    • Matsumoto, T.1
  • 29
    • 80052633753 scopus 로고    scopus 로고
    • Eldecalcitol: A review of its use in the treatment of osteoporosis
    • Sanford M, McCormack PL (2011) Eldecalcitol: A review of its use in the treatment of osteoporosis. Drugs 71(13):1755-1770.
    • (2011) Drugs , vol.71 , Issue.13 , pp. 1755-1770
    • Sanford, M.1    McCormack, P.L.2
  • 30
    • 80052278079 scopus 로고    scopus 로고
    • A new active vitamin D3 analog, eldecalcitol, prevents the risk of osteoporotic fractures - A randomized, active comparator, double-blind study
    • Matsumoto T, et al. (2011) A new active vitamin D3 analog, eldecalcitol, prevents the risk of osteoporotic fractures-a randomized, active comparator, double-blind study. Bone 49(4):605-612.
    • (2011) Bone , vol.49 , Issue.4 , pp. 605-612
    • Matsumoto, T.1
  • 31
    • 79960617710 scopus 로고    scopus 로고
    • Effect of eldecalcitol, an active vitamin D analog, on hip structure and biomechanical properties: 3D assessment by clinical CT
    • Ito M, Nakamura T, Fukunaga M, Shiraki M, Matsumoto T (2011) Effect of eldecalcitol, an active vitamin D analog, on hip structure and biomechanical properties: 3D assessment by clinical CT. Bone 49(3):328-334.
    • (2011) Bone , vol.49 , Issue.3 , pp. 328-334
    • Ito, M.1    Nakamura, T.2    Fukunaga, M.3    Shiraki, M.4    Matsumoto, T.5
  • 32
    • 0026310690 scopus 로고
    • A novel synthetic vitamin D3 analogue, 2-beta-(3-hydrox-ypropoxy)- calcitriol (ED-71): Its biological activities and pharmacological effects on calcium metabolism
    • Okano T, et al. (1991) A novel synthetic vitamin D3 analogue, 2-beta-(3-hydrox-ypropoxy)-calcitriol (ED-71): Its biological activities and pharmacological effects on calcium metabolism. Contrib Nephrol 91:116-122.
    • (1991) Contrib Nephrol , vol.91 , pp. 116-122
    • Okano, T.1
  • 33
    • 84859727262 scopus 로고    scopus 로고
    • The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice
    • Fukuhara S, et al. (2012) The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice. J Clin Invest 122(4): 1416-1426.
    • (2012) J Clin Invest , vol.122 , Issue.4 , pp. 1416-1426
    • Fukuhara, S.1
  • 34
    • 84864823667 scopus 로고    scopus 로고
    • Higher circulating sphingosine 1-phosphate levels are associated with lower bone mineral density and higher bone resorption marker in humans
    • Lee SH, et al. (2012) Higher circulating sphingosine 1-phosphate levels are associated with lower bone mineral density and higher bone resorption marker in humans. J Clin Endocrinol Metab 97(8):E1421-E1428.
    • (2012) J Clin Endocrinol Metab , vol.97 , Issue.8
    • Lee, S.H.1
  • 35
    • 53849136271 scopus 로고    scopus 로고
    • Vitamin D and human health: Lessons from vitamin D receptor null mice
    • Bouillon R, et al. (2008) Vitamin D and human health: Lessons from vitamin D receptor null mice. Endocr Rev 29(6):726-776.
    • (2008) Endocr Rev , vol.29 , Issue.6 , pp. 726-776
    • Bouillon, R.1
  • 38
    • 21844457949 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate and its receptors: An autocrine and paracrine network
    • Rosen H, Goetzl EJ (2005) Sphingosine 1-phosphate and its receptors: An autocrine and paracrine network. Nat Rev Immunol 5(7):560-570.
    • (2005) Nat Rev Immunol , vol.5 , Issue.7 , pp. 560-570
    • Rosen, H.1    Goetzl, E.J.2
  • 39
    • 17644365138 scopus 로고    scopus 로고
    • Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs
    • Cyster JG (2005) Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs. Annu Rev Immunol 23:127-159.
    • (2005) Annu Rev Immunol , vol.23 , pp. 127-159
    • Cyster, J.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.