Decreased zinc availability affects glutathione metabolism in neuronal cells and in the developing brain

Toxicological Sciences

Volumn 133, Issue 1, 2013, Pages 90-100

  Omata, Yo ^a   Salvador, Gabriela A ^b   Supasai, Suangsuda ^a   Keenan, Alison H ^a   Oteiza, Patricia I ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

Author keywords

Glutamylcysteine synthetase; Dopamine; Glutathione; Neuron; Nrf2; Zinc; Zinc deficiency

Indexed keywords

CASPASE 3; DOPAMINE; GAMMA GLUTAMYLCYSTEINE SYNTHETASE CATALYTIC SUBUNIT; GAMMA GLUTAMYLCYSTEINE SYNTHETASE MODIFIER SUBUNIT; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; MESSENGER RNA; PROTEIN; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ZINC;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVE SITE; FEMALE; FETUS; GENETIC TRANSCRIPTION; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; MALE; NERVE CELL; NEUROBLASTOMA CELL; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; ZINC DEFICIENCY;

ANIMALS; BLOTTING, WESTERN; BRAIN; CASPASE 3; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEMALE; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; HUMANS; NEURONS; NF-E2-RELATED FACTOR 2; ORGANOGENESIS; PREGNANCY; PRENATAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN SUBUNITS; RATS; RATS, SPRAGUE-DAWLEY; UP-REGULATION; ZINC;

RATTUS;

EID: 84876808500     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft022     Document Type: Article

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