Upper gastrointestinal bleeding associated with NSAIDs, other drugs and interactions: A nested case-control study in a new general practice database

European Journal of Clinical Pharmacology

Volumn 69, Issue 3, 2013, Pages 691-701

  De Abajo, Francisco J ^a,b,d   Gil, Miguel J ^a   Bryant, Verónica ^a   Timoner, Julia ^a   Oliva, Belén ^a   García Rodríguez, Luis A ^c  

^a Spanish Agency for Medicines and Medical Devices   (Spain)

^b HOSPITAL UNIVERSITARIO PRÍNCIPE DE ASTURIAS   (Spain)

^c Department of Pharmacoepidemiology   (Spain)

^d UNIVERSITY OF ALCALÁ   (Spain)

Author keywords

Acid suppressing drugs; Adverse drug reactions; NSAIDs; Upper gastrointestinal bleeding

Indexed keywords

ACECLOFENAC; ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; CORTICOSTEROID; DIPYRONE; HISTAMINE H2 RECEPTOR ANTAGONIST; IBUPROFEN; KETOPROFEN; LORNOXICAM; NITRATE; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; PIROXICAM; PROTON PUMP INHIBITOR; SEROTONIN UPTAKE INHIBITOR; STEROID;

ADULT; AGED; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG POTENTIATION; DRUG SAFETY; FEMALE; HUMAN; INCIDENCE; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK ASSESSMENT; RISK REDUCTION; TREND STUDY; UPPER GASTROINTESTINAL BLEEDING;

ADULT; ADVERSE DRUG REACTION REPORTING SYSTEMS; AGED; AGED, 80 AND OVER; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CASE-CONTROL STUDIES; DATABASES, FACTUAL; DRUG INTERACTIONS; FEMALE; GASTROINTESTINAL HEMORRHAGE; GENERAL PRACTICE; HISTAMINE H2 ANTAGONISTS; HUMANS; INCIDENCE; LOGISTIC MODELS; MALE; MIDDLE AGED; ODDS RATIO; PROTON PUMP INHIBITORS; REGISTRIES; RISK ASSESSMENT; RISK FACTORS; SPAIN; TIME FACTORS;

EID: 84876802329     PISSN: 00316970     EISSN: 14321041     Source Type: Journal    
DOI: 10.1007/s00228-012-1386-3     Document Type: Article

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