Effect of Erica sp. honey against microorganisms of clinical importance: Study of the factors underlying this biological activity

Molecules

Volumn 18, Issue 4, 2013, Pages 4233-4246

  Feás, Xesus ^a   Iglesias, Antonio ^a   Rodrigues, Sandra ^b   Estevinho, Leticia M ^b  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b INSTITUTO POLITÉCNICO DE BRAGANÇA   (Portugal)

Author keywords

Antibacterial properties; Antifungal properties; Heather honey; Hydrogen peroxide; Polyphenols; Sugars

Indexed keywords

ANTIINFECTIVE AGENT; CATALASE; FLAVONOID; HYDROGEN PEROXIDE; PHENOL DERIVATIVE; PLANT EXTRACT;

ARTICLE; CHEMISTRY; ERICACEAE; FOOD CONTAMINATION; FOOD CONTROL; HONEY; METABOLISM; MICROBIAL SENSITIVITY TEST;

ANTI-INFECTIVE AGENTS; CATALASE; ERICACEAE; FLAVONOIDS; FOOD CONTAMINATION; FOOD MICROBIOLOGY; HONEY; HYDROGEN PEROXIDE; MICROBIAL SENSITIVITY TESTS; PHENOLS; PLANT EXTRACTS;

EID: 84876772688     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules18044233     Document Type: Article

References (46)

1. Tenover, F.C. Mechanisms of antimicrobial resistance in bacteria. Am. J. Infect. Control 2006, 34, 3-10.
2. Livermore, D.M. Bacterial resistance: Origins, Epidemiology, and impact. Clin. Infect. Dis. 2003, 36, 11-23.
3. Cutler, J.E.; Deepe, G.S., Jr.; Klein, B.S. Advances in combating fungal diseases: vaccines on the threshold. Nat. Rev. Micro. 2007, 5, 13-28.
4. Brudzynski, K.; Lannigan, R. Mechanism of honey bacteriostatic action against MRSA and VRE involves hydroxyl radicals generated from honey's hydrogen peroxide. Front. Microbiol. 2012, 3, 1-8.
5. Brudzynski, C.; Abubaker, A.; St-Martin, L.; Castle, A. Re-examining the role of hydrogen peroxide in bacteriostatic and bactericidal activities of honey. Front. Microbiol. 2011, 2, 213.
6. Sajid, M.; Azim, M.K. Characterization of the nematicidal activity of natural honey. J. Agric. Food Chem. 2012, 60, 7428-7434.
7. Molan, P. Why honey is effective as a medicine. Bee World 2001, 82, 22-40.
8. Estevinho, L.M.; Afonso, S.E.; Feás, X. Antifungal effect of lavender honey against Candida albicans, Candida krusei and Cryptococcus neoformans. J. Food Sci. Technol. 2011, 48, 640-643.
9. Irish, J.; Carter, D.A.; Shokohi, T.; Blair, S. Honey has an antifungal effect against Candida species. Med. Mycol. 2006, 44, 289-291.
10. Estevinho, L.; Pereira, A.P.; Moreira, L.; Dias, L.G.; Pereira, E. Antioxidant and antimicrobial effects of phenolic compounds extracts of Northeast Portugal honey. Food Chem. Toxicol. 2008, 46, 3774-3779.
11. Erejuwa, O.O.; Sulaiman, S.A.; Ab Wahab, M.S. Honey: A Novel Antioxidant. Molecules 2012, 17, 4400-4423.
12. Ghashm, A.A.; Othman, N.H.; Khattak, M.N.; Ismail N.M.; Saini, R. Antiproliferative effect of Tualang honey on oral squamous cell carcinoma and osteosarcoma cell lines. BMC Complement. Altern. Med. 2010, 14, 49.
13. Haynes, J.S. Achieving clinical outcomes: The use of honey. Wound Essentials 2011, 6, 14-19.
14. Molan, P.C. Potential of honey in the treatment of wounds and burns. Am. J. Clin. Dermatol. 2001, 2, 13-19.
15. Lusby, P.E.; Coombes, A.L.; Wilkinson, J.M. Bactericidal activity of different honeys against pathogenic bacteria. Arch. Med. Res. 2005, 36, 464-467.
16. Kwakman, P.H.; te Velde, A.A.; de Boer, L.; Speijer, D.; Vandenbroucke-Grauls, C.M.; Zaat, S.A. How honey kills bacteria. FASEB J. 2010, 24, 2576-2582.
17. Chen, C.; Campbell, L.T.; Blair, S.E.; Carter, D.A. The effect of standard heat and filtration processing procedures on antimicrobial activity and hydrogen peroxide levels in honey. Front. Microbiol. 2012, 3, 1-7.
18. Tucak, Z.; Periskić, M.; Beslo, D.; Tucak, I. Influence of the beehive type on the quality of honey. Coll. Antropol. 2004, 28, 463-467.
19. Witczak, M.; Juszczak, L.; Gałkowska, D. Non-Newtonian behaviour of heather honey. J. Food Eng. 2011, 104, 532-537.
20. Harfani, H.; Bouanani, N.; Aziz, M.; Caid, H.; Ghalim, N.; Amrani, S. The hypolipidaemic activity of aqueous Erica multiflora flowers extract in Triton WR-1339 induced hyperlipidaemic rats: a comparison with fenofibrate. J. Ethnopharmacol. 2007, 109, 156-160.
21. Akkol, E.; Yesxilada, E.; Güvenc, A. Valuation of anti-inflammatory and antinociceptive activities of Erica species native to Turkey. J. Ethnopharmacol. 2007, 116, 251-257.
22. Tuzlaci, E.; Aymaz, E.P. Turkish folk medicinal plants, Part IV: Gönen (Balikesir). Fitoterapia 2001, 72, 323-343.
23. Andrade P.,B.; Amaral M.T.; Isabel, P.; Carvalho, J.; Seabra, R.; Cunha, A. Physicochemical attributes and pollen spectrum of Portuguese heather honeys. Food Chem. 1999, 66, 503-510.
24. Pires, J.; Estevinho, M.L.; Feás, X.; Cantalapiedra, J.; Iglesias, A. Pollen spectrum and physico-chemical attributes of heather (Erica sp.) honeys of north Portugal. J. Sci. Food Agric. 2009, 89, 1862-1870.
25. Oelschlägel, S. Characterization of unifloral honeys using HS-SPME/GC/MS. Proceedings of the 42nd APIMONDIA 2011, Buenos Aires-Argentina. Available online: http://www.apinews.com/ pdf/apimondia2011/technologyquality/ characterization-of-unifloral-honeys-using-hs-spme-gc-msstefanie- oelschlagel.pdf (accessed on 19 March 2013).
26. Dias, L.A.; Peres, AM.; Vilas-Boas, M.; Rocha, M.A.; Estevinho, L.; Machado, A.A.S.C. An electronic tongue for honey classification. Microchim. Acta 2008, 163, 97-102.
27. Henriques, A.; Burton, N.F.; Cooper, R.A. Antibacterial activity of selected Portuguese honeys. J. Apic. Res. 2005, 44, 119-123.
28. Estevinho, L.M.; Feás, X.; Seijas, J.A.; Vázquez-Tato, M.P. Organic honey from Trás-Os-Montes region (Portugal): Chemical, palynological, microbiological and bioactive compounds characterization. Food Chem. Toxicol. 2012, 50, 258-264.
29. Feás, X.; Estevinho, L.M. A survey of the in vitro antifungal activity of heather (Erica sp.) organic honey. J. Med. Food 2011, 14, 1-5.
30. Carter, C.; Thornburg, R.W. Is the nectar redox cycle a floral defense against microbial attack? Trends Plant Sci. 2004, 9, 320-324.
31. Toro, M.V.; García, M.D.; Pascual, M. Isolement et identification des acides phènols chez Erica andevalensis Cabezudo-Ribera: leur contribution à l'activité antimicrobienne de l'espèce. Ann. Pharm. Fr. 1987, 45, 401-407.
32. Reyes, M.; Martín-Cordero, C.; Ayuso, M.J.; Toro, M.V.; Alarcon de la Lastra, C. Antiulcer activity in rats by flavonoids of Erica andevalensis Cabezudo-Rivera. Phytother. Res. 1996, 10, 300-303.
33. Güvenç A.; Kendir, G.; Eken, A. Evaluation of inorganic compounds of Erica L. species (Ericaceae) native to Turkey. FABAD J. Pharm. Sci. 2007, 32, 121-125.
34. Pyrzyńska, K.; Biesaga, M. Analysis of phenolic acids and flavonoids in honey. Trends Anal. Chem. 2009, 28, 893-902.
35. Ferreira, I.C.F.R.; Aires, E.; Barreira, J.C.M.; Estevinho, M.L. Antioxidant activity of Portuguese honey samples: Different contributions of the entire honey and phenolic extract. Food Chem. 2009, 114, 1438-1443.
36. Bogdanov, S. Honey as Nutrient and Functional Food: A Review. Available online: http://www.apitherapie.ch/files/files/Honig/ 8HoneyNutrientFunctionalReview.pdf (accessed on 11 May 2012).
37. Weston, R. The contribution of catalase and other natural products to the antibacterial activity of honey: A review. Food Chem. 2000, 71, 235-239.
38. Kwakman, P.H.S.; Velde, A.A.; Boer, L.; Vandenbroucke-Grauls, C.M.J.E.; Zaat, S.A.J. Two Major Medicinal Honeys Have Different Mechanisms of Bactericidal Activity. PLoS One 2011, 6, e17709.
39. Pappas, P.G.; Rex, J.H.; Lee, J.; Hamill, R.J.; Larsen, R.A.; Powderly, W.; Kauffman, C.A.; Hyslop, N.; Mangino, J.E.; Chapman, S.; et al. A prospective observational study of candidemia: Epidemiology, Therapy, and influences on mortality in hospitalized adult and pediatric patients. Clin. Infect. Dis. 2003, 37, 634-643.
40. Perfect, J.R.; Casadevall, A. Cryptococcosis. Infect. Dis. Clin. North Am. 2002, 16, 837-874.
41. Molan, P.C. The antibacterial activity of honey. 1. The nature of the antibacterial activity. Bee World 1992, 73, 5-28.
42. Xu, P.; Shi, M.; Chen, X.-X. Antimicrobial peptide evolution in the asiatic honey bee Apis cerana. PLoS One 2004, 4, e4239.
43. Oelschlaegel, S.; Pieper, L.; Staufenbiel, R.; Gruner, M.; Zeippert, L.; Pieper, B.; Koelling-Speer, I.; Speer, K. Floral markers of cornflower (Centaurea cyanus) honey and its peroxide antibacterial activity for an alternative treatment of digital dermatitis. J. Agric. Food Chem. 2012, 60, 11811-11820.
44. Feás, X.; Pires, J.; Estevinho, M.L.; Iglesias, A.; Araujo, J.P.P. Palynological and physicochemical data characterisation of honeys produced in the Entre-Douro e Minho region of Portugal. Int. J. Food Sci. Tech. 2010, 45, 1255-1262.
45. Iglesias, A.; Feás, X.; Rodrigues, S.; Seijas, J.A.; Vázquez-Tato, M.P.; Dias, L.G.; Estevinho, L.M. Comprehensive study of honey with protected denomination of origin and contribution to the enhancement of legal specifications. Molecules 2012, 17, 8561-8577.
46. Morais, M.; Moreira, L.; Feás, X.; Estevinho, L.M. Honeybee-collected pollen from five Portuguese Natural Parks: Palynological origin, Phenolic content, Antioxidant properties and antimicrobial activity. Food Chem. Toxicol. 2011, 49, 1096-1101.