-
1
-
-
50949119251
-
The editor's roundtable: Lipid management beyond statins - Reducing residual cardiovascular risk
-
Friedewald, V. E. Jr, Ballantyne, C. M., Davidson, M. H., Guyton, J. R. & Roberts, W. C. The editor's roundtable: lipid management beyond statins - reducing residual cardiovascular risk. Am. J. Cardiol 102, 559-567 (2008).
-
(2008)
Am. J. Cardiol
, vol.102
, pp. 559-567
-
-
Friedewald Jr., V.E.1
Ballantyne, C.M.2
Davidson, M.H.3
Guyton, J.R.4
Roberts, W.C.5
-
2
-
-
79955653216
-
Clinical review: The evolving role of HDL in the treatment of high-risk patients with cardiovascular disease
-
Brewer, H. B. Jr. Clinical review: The evolving role of HDL in the treatment of high-risk patients with cardiovascular disease. J. Clin. Endocrinol. Metab. 96, 1246-1257 (2011).
-
(2011)
J. Clin. Endocrinol. Metab.
, vol.96
, pp. 1246-1257
-
-
Brewer, Jr.H.B.1
-
3
-
-
82955168412
-
HDL-C: Role as a risk modifier
-
Barter, P. HDL-C: role as a risk modifier. Atheroscler. Suppl. 12, 267-270 (2011).
-
Atheroscler. Suppl.
, vol.12
, Issue.267-270
, pp. 2011
-
-
Barter, P.1
-
4
-
-
84862502750
-
Lipid-related markers and cardiovascular disease prediction
-
Emerging Risk Factors Collaboration et al.
-
Emerging Risk Factors Collaboration et al. Lipid-related markers and cardiovascular disease prediction. JAMA 307, 2499-2506 (2012).
-
(2012)
JAMA
, vol.307
, pp. 2499-2506
-
-
-
5
-
-
34748887666
-
HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events
-
Barter, P. et al. HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events. N. Engl. J. Med. 357, 1301-1310 (2007).
-
(2007)
N. Engl. J. Med.
, vol.357
, pp. 1301-1310
-
-
Barter, P.1
-
6
-
-
84859760161
-
Cholesterol efflux and atheroprotection: Advancing the concept of reverse cholesterol transport
-
Rosenson, R. S. et al. Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport. Circulation 125, 1905-1919 (2012).
-
(2012)
Circulation
, vol.125
, pp. 1905-1919
-
-
Rosenson, R.S.1
-
7
-
-
77949429915
-
High-density lipoproteins and cardiovascular disease: 2010 update
-
Alwaili, K., Awan, Z., Alshahrani, A. & Genest, J. High-density lipoproteins and cardiovascular disease: 2010 update. Expert Rev. Cardiovasc. Ther. 8, 413-423 (2010).
-
(2010)
Expert Rev. Cardiovasc. Ther.
, vol.8
, pp. 413-423
-
-
Alwaili, K.1
Awan, Z.2
Alshahrani, A.3
Genest, J.4
-
8
-
-
79551574145
-
Recombinant high-density lipoprotein formulations
-
Vucic, E. & Rosenson, R. S. Recombinant high-density lipoprotein formulations. Curr. Atheroscler Rep. 13, 81-87 (2011).
-
(2011)
Curr. Atheroscler Rep.
, vol.13
, pp. 81-87
-
-
Vucic, E.1
Rosenson, R.S.2
-
9
-
-
60549091035
-
High-density lipoproteins, inflammation and oxidative stress
-
Tabet, F. & Rye, K. A. High-density lipoproteins, inflammation and oxidative stress. Clin. Sci. (Lond.) 116, 87-98 (2009).
-
(2009)
Clin. Sci. (Lond.)
, vol.116
, pp. 87-98
-
-
Tabet, F.1
Rye, K.A.2
-
10
-
-
38849140840
-
Is raising HDL a futile strategy for atheroprotection?
-
Joy, T. & Hegele, R. A. Is raising HDL a futile strategy for atheroprotection? Nat. Rev. Drug Discov. 7, 143-155 (2008).
-
(2008)
Nat. Rev. Drug Discov.
, vol.7
, pp. 143-155
-
-
Joy, T.1
Hegele, R.A.2
-
11
-
-
69849109122
-
Update on strategies to increase HDL quantity and function
-
Duffy, D. & Rader, D. J. Update on strategies to increase HDL quantity and function. Nat. Rev. Cardiol. 6, 455-463 (2009).
-
(2009)
Nat. Rev. Cardiol.
, vol.6
, pp. 455-463
-
-
Duffy, D.1
Rader, D.J.2
-
12
-
-
79957882578
-
Metabolic and functional relevance of HDL subspecies
-
Asztalos, B. F., Tani, M. & Schaefer, E. J. Metabolic and functional relevance of HDL subspecies. Curr. Opin. Lipidol. 22, 176-185 (2011).
-
(2011)
Curr. Opin. Lipidol.
, vol.22
, pp. 176-185
-
-
Asztalos, B.F.1
Tani, M.2
Schaefer, E.J.3
-
13
-
-
33847368173
-
Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL
-
Vaisar, T. et al. Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL. J. Clin. Invest. 117, 746-756 (2007).
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 746-756
-
-
Vaisar, T.1
-
14
-
-
78049276598
-
Anti-inflammatory properties of paraoxonase-1 in atherosclerosis
-
Mackness, B. & Mackness, M. Anti-inflammatory properties of paraoxonase-1 in atherosclerosis. Adv. Exp. Med. Biol. 660, 143-151 (2010).
-
(2010)
Adv. Exp. Med. Biol.
, vol.660
, pp. 143-151
-
-
Mackness, B.1
Mackness, M.2
-
15
-
-
84863985473
-
HDL functionality
-
Soran, H., Hama, S., Yadav, R. & Durrington, P. N. HDL functionality. Curr. Opin. Lipidol. 23, 353-366 (2012).
-
(2012)
Curr. Opin. Lipidol.
, vol.23
, pp. 353-366
-
-
Soran, H.1
Hama, S.2
Yadav, R.3
Durrington, P.N.4
-
16
-
-
78651379500
-
Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis
-
Khera, A. V. et al. Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis. N. Engl. J. Med. 364, 127-135 (2011).
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 127-135
-
-
Khera, A.V.1
-
17
-
-
77950894330
-
The ability to promote efflux via ABCA1 determines the capacity of serum specimens with similar high-density lipoprotein cholesterol to remove cholesterol from macrophages
-
de la Llera-Moya, M. et al. The ability to promote efflux via ABCA1 determines the capacity of serum specimens with similar high-density lipoprotein cholesterol to remove cholesterol from macrophages. Arterioscler. Thromb. Vasc. Biol. 30, 796-801 (2010).
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 796-801
-
-
De La Llera-Moya, M.1
-
18
-
-
79955476272
-
Novel HDL-directed pharmacotherapeutic strategies
-
Degoma, E. M. & Rader, D. J. Novel HDL-directed pharmacotherapeutic strategies. Nat. Rev. Cardiol. 8, 266-277 (2011).
-
(2011)
Nat. Rev. Cardiol.
, vol.8
, pp. 266-277
-
-
Degoma, E.M.1
Rader, D.J.2
-
19
-
-
63249098212
-
High-density lipoprotein/apolipoprotein A-I infusion therapy
-
Tardif, J. C., Heinonen, T. & Noble, S. High-density lipoprotein/apolipoprotein A-I infusion therapy. Curr. Atheroscler. Rep. 11, 58-63 (2009).
-
(2009)
Curr. Atheroscler. Rep.
, vol.11
, pp. 58-63
-
-
Tardif, J.C.1
Heinonen, T.2
Noble, S.3
-
20
-
-
84861342498
-
Genetic lecithin: Cholesterol acyltransferase deficiency and cardiovascular disease
-
Calabresi, L., Simonelli, S., Gomaraschi, M. & Franceschini, G. Genetic lecithin: cholesterol acyltransferase deficiency and cardiovascular disease. Atherosclerosis 222, 299-306 (2012).
-
(2012)
Atherosclerosis
, vol.222
, pp. 299-306
-
-
Calabresi, L.1
Simonelli, S.2
Gomaraschi, M.3
Franceschini, G.4
-
21
-
-
84861230283
-
Genetics of cholesterol efflux
-
Iatan, I., Palmyre, A., Alrasheed, S., Ruel, I. & Genest, J. Genetics of cholesterol efflux. Curr. Atheroscler. Rep. 14, 235-246 (2012).
-
(2012)
Curr. Atheroscler. Rep.
, vol.14
, pp. 235-246
-
-
Iatan, I.1
Palmyre, A.2
Alrasheed, S.3
Ruel, I.4
Genest, J.5
-
22
-
-
0029615430
-
Apolipoprotein A-I deficiency. Biochemical and metabolic characteristics
-
Ng, D. S. et al. Apolipoprotein A-I deficiency. Biochemical and metabolic characteristics. Arterioscler. Thromb. Vasc Biol. 15, 2157-2164 (1995).
-
(1995)
Arterioscler. Thromb. Vasc Biol.
, vol.15
, pp. 2157-2164
-
-
Ng, D.S.1
-
23
-
-
84857628622
-
Increased risk of coronary artery disease in Caucasians with extremely low HDL cholesterol due to mutations in ABCA1
-
Tietjen, I. et al. Increased risk of coronary artery disease in Caucasians with extremely low HDL cholesterol due to mutations in ABCA1, APOA1, and LCAT. Biochim. Biophys. Acta 1821, 416-424 (2012).
-
(2012)
APOA1, and LCAT. Biochim. Biophys. Acta 1821
, pp. 416-424
-
-
Tietjen, I.1
-
24
-
-
79954515931
-
Cholesteryl ester transfer protein: The controversial relation to atherosclerosis and emerging new biological roles
-
Oliveira, H. C. & de Faria, E. C. Cholesteryl ester transfer protein: the controversial relation to atherosclerosis and emerging new biological roles. IUBMB Life 63, 248-257 (2011).
-
(2011)
IUBMB Life
, vol.63
, pp. 248-257
-
-
Oliveira, H.C.1
De Faria, E.C.2
-
25
-
-
78651352098
-
Genetic variant of the scavenger receptor BI in humans
-
Vergeer, M. et al. Genetic variant of the scavenger receptor BI in humans. N. Engl. J. Med. 364, 136-145 (2011).
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 136-145
-
-
Vergeer, M.1
-
26
-
-
0027162816
-
Hepatic lipase deficiency. Clinical, biochemical, and molecular genetic characteristics
-
Hegele, R. A. et al. Hepatic lipase deficiency. Clinical, biochemical, and molecular genetic characteristics. Arterioscler. Thromb. 13, 720-728 (1993).
-
(1993)
Arterioscler. Thromb.
, vol.13
, pp. 720-728
-
-
Hegele, R.A.1
-
27
-
-
44649140474
-
Association of loss of function mutations in the ABCA1 gene with high-density lipoprotein cholesterol levels and risk of ischemic heart disease
-
Frikke-Schmidt, R. et al. Association of loss of function mutations in the ABCA1 gene with high-density lipoprotein cholesterol levels and risk of ischemic heart disease. JAMA 299, 2524-2532 (2008).
-
(2008)
JAMA
, vol.299
, pp. 2524-2532
-
-
Frikke-Schmidt, R.1
-
28
-
-
65249148632
-
Hepatic lipase, genetically elevated high-density lipoprotein, and risk of ischemic cardiovascular disease
-
Johannsen, T. H. et al. Hepatic lipase, genetically elevated high-density lipoprotein, and risk of ischemic cardiovascular disease. J. Clin. Endocrinol. Metab. 94, 1264-1273 (2009).
-
(2009)
J. Clin. Endocrinol. Metab.
, vol.94
, pp. 1264-1273
-
-
Johannsen, T.H.1
-
29
-
-
84856786437
-
LCAT, HDL cholesterol and ischemic cardiovascular disease: A Mendelian randomization study of HDL cholesterol in 54,500 individuals
-
Haase, C. L. et al. LCAT, HDL cholesterol and ischemic cardiovascular disease: a Mendelian randomization study of HDL cholesterol in 54,500 individuals. J. Clin. Endocrinol. Metab. 97, E248-E256 (2012).
-
(2012)
J. Clin. Endocrinol. Metab.
, vol.97
-
-
Haase, C.L.1
-
30
-
-
84864845456
-
Plasma HDL cholesterol and risk of myocardial infarction: A Mendelian randomisation study
-
Voight, B. F. et al. Plasma HDL cholesterol and risk of myocardial infarction: a Mendelian randomisation study. Lancet 380, 572-580 (2012).
-
(2012)
Lancet
, vol.380
, pp. 572-580
-
-
Voight, B.F.1
-
31
-
-
0023001772
-
Fifteen year mortality in Coronary Drug Project patients: Long-term benefit with niacin
-
Canner, P. L. et al. Fifteen year mortality in Coronary Drug Project patients: long-term benefit with niacin. J. Am. Coll. Cardiol. 8, 1245-1255 (1986).
-
(1986)
J. Am. Coll. Cardiol.
, vol.8
, pp. 1245-1255
-
-
Canner, P.L.1
-
32
-
-
0023232216
-
Helsinki Heart Study: Primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease
-
Frick, M. H. et al. Helsinki Heart Study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease. N. Engl. J. Med. 317, 1237-1245 (1987).
-
(1987)
N. Engl. J. Med.
, vol.317
, pp. 1237-1245
-
-
Frick, M.H.1
-
33
-
-
0033527030
-
Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group
-
Rubins, H. B. et al. Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group. N. Engl. J. Med. 341, 410-418 (1999).
-
(1999)
N. Engl. J. Med.
, vol.341
, pp. 410-418
-
-
Rubins, H.B.1
-
34
-
-
77951704587
-
Effects of combination lipid therapy in type 2 diabetes mellitus
-
ACCORD Study Group et al. Effects of combination lipid therapy in type 2 diabetes mellitus. N. Engl. J. Med. 362, 1563-1574 (2010).
-
(2010)
N. Engl. J. Med.
, vol.362
, pp. 1563-1574
-
-
Study Group, A.1
-
35
-
-
84855171302
-
Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy
-
AIM-HIGH Investigators et al.
-
AIM-HIGH Investigators et al. Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy. N. Engl. J. Med. 365, 2255-2267 (2011).
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 2255-2267
-
-
-
36
-
-
62349105940
-
Long-term benefit of high-density lipoprotein cholesterol-raising therapy with bezafibrate: 16-year mortality follow-up of the bezafibrate infarction prevention trial
-
Goldenberg, I. et al. Long-term benefit of high-density lipoprotein cholesterol-raising therapy with bezafibrate: 16-year mortality follow-up of the bezafibrate infarction prevention trial. Arch. Intern. Med. 169, 508-514 (2009).
-
(2009)
Arch. Intern. Med.
, vol.169
, pp. 508-514
-
-
Goldenberg, I.1
-
37
-
-
77952708442
-
Effects of fibrates on cardiovascular outcomes: A systematic review and meta-analysis
-
Jun, M. et al. Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysis. Lancet 375, 1875-1884 (2010).
-
(2010)
Lancet 375
, pp. 1875-1884
-
-
Jun, M.1
-
38
-
-
84876757899
-
-
Merck (Extended-Release NiacinLaropiprant) Did Not Achieve Primary Endpoint [online]
-
Merck. Merck announces HPS2-THRIVE study of Tredaptive™ (Extended-Release Niacin/Laropiprant) did not achieve primary endpoint [online], http://www.mercknewsroom.com/press-release/prescription-medicine-news/merck- announces-hps2-thrive-study-tredaptive-extended-relea (2012).
-
(2012)
Merck Announces HPS2-THRIVE Study of Tredaptive™
-
-
-
39
-
-
42649134146
-
ABC transporters, and cholesterol efflux: Implications for the treatment of atherosclerosis
-
Tall, A. R., Yvan-Charvet, L., Terasaka, N., Pagler, T. & Wang, N. HDL, ABC transporters, and cholesterol efflux: implications for the treatment of atherosclerosis. Cell Metab. 7, 365-375 (2008).
-
(2008)
Cell Metab.
, vol.7
, pp. 365-375
-
-
Tall, A.R.1
Yvan-Charvet, L.2
Terasaka, N.3
Pagler, T.4
Hdl, W.N.5
-
40
-
-
84863981772
-
Rationale for cholesteryl ester transfer protein inhibition
-
Hewing, B. & Fisher, E. A. Rationale for cholesteryl ester transfer protein inhibition. Curr. Opin. Lipidol. 23, 372-376 (2012).
-
(2012)
Curr. Opin. Lipidol.
, vol.23
, pp. 372-376
-
-
Hewing, B.1
Fisher, E.A.2
-
41
-
-
36348975228
-
Effects of torcetrapib in patients at high risk for coronary events
-
Barter, P. J. et al. Effects of torcetrapib in patients at high risk for coronary events. N. Engl. J. Med. 357, 2109-2122 (2007).
-
(2007)
N. Engl. J. Med.
, vol.357
, pp. 2109-2122
-
-
Barter, P.J.1
-
42
-
-
66449084532
-
Torcetrapib induces aldosterone and cortisol production by an intracellular calcium-mediated mechanism independently of cholesteryl ester transfer protein inhibition
-
Hu, X. et al. Torcetrapib induces aldosterone and cortisol production by an intracellular calcium-mediated mechanism independently of cholesteryl ester transfer protein inhibition. Endocrinology 150, 2211-2219 (2009).
-
(2009)
Endocrinology
, vol.150
, pp. 2211-2219
-
-
Hu, X.1
-
43
-
-
34047106220
-
Effect of torcetrapib on the progression of coronary atherosclerosis
-
Nissen, S. E. et al. Effect of torcetrapib on the progression of coronary atherosclerosis. N. Engl. J. Med. 356, 1304-1316 (2007).
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 1304-1316
-
-
Nissen, S.E.1
-
44
-
-
58149380516
-
Cholesteryl ester transfer protein inhibitor torcetrapib and off-target toxicity: A pooled analysis of the rating atherosclerotic disease change by imaging with a new CETP inhibitor (RADIANCE) trials
-
Vergeer, M. et al. Cholesteryl ester transfer protein inhibitor torcetrapib and off-target toxicity: a pooled analysis of the rating atherosclerotic disease change by imaging with a new CETP inhibitor (RADIANCE) trials. Circulation 118, 2515-2522 (2008).
-
(2008)
Circulation
, vol.118
, pp. 2515-2522
-
-
Vergeer, M.1
-
45
-
-
58149386896
-
Cholesteryl ester transfer protein inhibition, high-density lipoprotein raising, and progression of coronary atherosclerosis: Insights from ILLUSTRATE (Investigation of Lipid Level Management Using Coronary Ultrasound to Assess Reduction of Atherosclerosis by CETP Inhibition and HDL Elevation)
-
Nicholls, S. J., Tuzcu, E. M., Brennan, D. M., Tardif, J. C. & Nissen, S. E. Cholesteryl ester transfer protein inhibition, high-density lipoprotein raising, and progression of coronary atherosclerosis: insights from ILLUSTRATE (Investigation of Lipid Level Management Using Coronary Ultrasound to Assess Reduction of Atherosclerosis by CETP Inhibition and HDL Elevation). Circulation 118, 2506-2514 (2008).
-
(2008)
Circulation
, vol.118
, pp. 2506-2514
-
-
Nicholls, S.J.1
Tuzcu, E.M.2
Brennan, D.M.3
Tardif, J.C.4
Nissen, S.E.5
-
46
-
-
84863789387
-
Cholesteryl ester transfer protein inhibition as a strategy to reduce cardiovascular risk
-
Barter, P. J. & Rye, K. A. Cholesteryl ester transfer protein inhibition as a strategy to reduce cardiovascular risk. J. Lipid Res. 53, 1755-1766 (2012).
-
(2012)
J. Lipid Res.
, vol.53
, pp. 1755-1766
-
-
Barter, P.J.1
Rye, K.A.2
-
47
-
-
84870045994
-
Effects of dalcetrapib in patients with a recent acute coronary syndrome
-
Schwartz, G. G. et al. Effects of dalcetrapib in patients with a recent acute coronary syndrome. N. Engl. J. Med. 367, 2089-2099 (2012).
-
(2012)
N. Engl. J. Med.
, vol.367
, pp. 2089-2099
-
-
Schwartz, G.G.1
-
48
-
-
84865329156
-
Dalcetrapib a cholesteryl ester transfer protein modulator
-
Hooper, A. J. & Burnett, J. R. Dalcetrapib, a cholesteryl ester transfer protein modulator. Expert Opin. Investig. Drugs 21, 1427-1432 (2012).
-
(2012)
Expert Opin. Investig. Drugs
, vol.21
, pp. 1427-1432
-
-
Hooper, A.J.1
Burnett, J.R.2
-
49
-
-
79960648677
-
Different effects of compounds decreasing cholesteryl ester transfer protein activity on lipoprotein metabolism
-
Niesor, E. J. Different effects of compounds decreasing cholesteryl ester transfer protein activity on lipoprotein metabolism. Curr. Opin. Lipidol. 22, 288-295 (2011).
-
(2011)
Curr. Opin. Lipidol.
, vol.22
, pp. 288-295
-
-
Niesor, E.J.1
|