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Volumn 57, Issue 5, 2013, Pages 1784-1792

Decreased iron burden in overweight C282Y homozygous women: Putative role of increased hepcidin production

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; FERRITIN; HEMOGLOBIN; HEPCIDIN; IRON; TRANSFERRIN;

EID: 84876743784     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.26261     Document Type: Article
Times cited : (14)

References (41)
  • 2
    • 9344224529 scopus 로고    scopus 로고
    • A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis
    • Feder JN, Gnirke A, Thomas W, Tsuchihashi Z, Ruddy DA, Basava A, et al. A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nat Genet 1996; 13: 399- 408.
    • (1996) Nat Genet , vol.13 , pp. 399-408
    • Feder, J.N.1    Gnirke, A.2    Thomas, W.3    Tsuchihashi, Z.4    Ruddy, D.A.5    Basava, A.6
  • 3
    • 0037460697 scopus 로고    scopus 로고
    • Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis
    • Bridle KR, Frazer DM, Wilkins SJ, Dixon JL, Purdie DM, Crawford DH, et al. Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis. Lancet 2003; 361: 669- 673.
    • (2003) Lancet , vol.361 , pp. 669-673
    • Bridle, K.R.1    Frazer, D.M.2    Wilkins, S.J.3    Dixon, J.L.4    Purdie, D.M.5    Crawford, D.H.6
  • 5
    • 65249151878 scopus 로고    scopus 로고
    • [Acquired and genetic factors influencing the penetrance of HFE haemochromatosis.]
    • discussion 881.
    • Deugnier Y, Bourgain C, Mosser J. [Acquired and genetic factors influencing the penetrance of HFE haemochromatosis.] Bull Acad Natl Med 2008; 192: 873- 881; discussion 881.
    • (2008) Bull Acad Natl Med , vol.192 , pp. 873-881
    • Deugnier, Y.1    Bourgain, C.2    Mosser, J.3
  • 6
    • 18544376989 scopus 로고    scopus 로고
    • Gender-specific phenotypic expression and screening strategies in C282Y-linked haemochromatosis: a study of 9396 French people
    • Deugnier Y, Jouanolle AM, Chaperon J, Moirand R, Pithois C, Meyer JF, et al. Gender-specific phenotypic expression and screening strategies in C282Y-linked haemochromatosis: a study of 9396 French people. Br J Haematol 2002; 118: 1170- 1178.
    • (2002) Br J Haematol , vol.118 , pp. 1170-1178
    • Deugnier, Y.1    Jouanolle, A.M.2    Chaperon, J.3    Moirand, R.4    Pithois, C.5    Meyer, J.F.6
  • 8
    • 0036163634 scopus 로고    scopus 로고
    • Excess alcohol greatly increases the prevalence of cirrhosis in hereditary hemochromatosis
    • Fletcher LM, Dixon JL, Purdie DM, Powell LW, Crawford DH. Excess alcohol greatly increases the prevalence of cirrhosis in hereditary hemochromatosis. Gastroenterology 2002; 122: 281- 289.
    • (2002) Gastroenterology , vol.122 , pp. 281-289
    • Fletcher, L.M.1    Dixon, J.L.2    Purdie, D.M.3    Powell, L.W.4    Crawford, D.H.5
  • 9
    • 0031743057 scopus 로고    scopus 로고
    • Clinical trial on the effect of regular tea drinking on iron accumulation in genetic haemochromatosis
    • Kaltwasser JP, Werner E, Schalk K, Hansen C, Gottschalk R, Seidl C. Clinical trial on the effect of regular tea drinking on iron accumulation in genetic haemochromatosis. Gut 1998; 43: 699- 704.
    • (1998) Gut , vol.43 , pp. 699-704
    • Kaltwasser, J.P.1    Werner, E.2    Schalk, K.3    Hansen, C.4    Gottschalk, R.5    Seidl, C.6
  • 10
    • 33645969263 scopus 로고    scopus 로고
    • HFE genotypes and dietary heme iron: no evidence of strong gene-nutrient interaction on serum ferritin concentrations in middle-aged women
    • van der AD, Peeters PH, Grobbee DE, Roest M, Voorbij HA, van der Schouw YT. HFE genotypes and dietary heme iron: no evidence of strong gene-nutrient interaction on serum ferritin concentrations in middle-aged women. Nutr Metab Cardiovasc Dis 2006; 16: 60- 68.
    • (2006) Nutr Metab Cardiovasc Dis , vol.16 , pp. 60-68
    • van der, A.D.1    Peeters, P.H.2    Grobbee, D.E.3    Roest, M.4    Voorbij, H.A.5    van der Schouw, Y.T.6
  • 11
    • 34548127058 scopus 로고    scopus 로고
    • Proton pump inhibitors suppress absorption of dietary non-haem iron in hereditary haemochromatosis
    • Hutchinson C, Geissler CA, Powell JJ, Bomford A. Proton pump inhibitors suppress absorption of dietary non-haem iron in hereditary haemochromatosis. Gut 2007; 56: 1291- 1295.
    • (2007) Gut , vol.56 , pp. 1291-1295
    • Hutchinson, C.1    Geissler, C.A.2    Powell, J.J.3    Bomford, A.4
  • 12
    • 1642367900 scopus 로고    scopus 로고
    • HAMP as a modifier gene that increases the phenotypic expression of the HFE pC282Y homozygous genotype
    • Jacolot S, Le Gac G, Scotet V, Quere I, Mura C, Ferec C. HAMP as a modifier gene that increases the phenotypic expression of the HFE pC282Y homozygous genotype. Blood 2004; 103: 2835- 2840.
    • (2004) Blood , vol.103 , pp. 2835-2840
    • Jacolot, S.1    Le Gac, G.2    Scotet, V.3    Quere, I.4    Mura, C.5    Ferec, C.6
  • 13
    • 4544314123 scopus 로고    scopus 로고
    • The recently identified type 2A juvenile haemochromatosis gene (HJV), a second candidate modifier of the C282Y homozygous phenotype
    • Le Gac G, Scotet V, Ka C, Gourlaouen I, Bryckaert L, Jacolot S, et al. The recently identified type 2A juvenile haemochromatosis gene (HJV), a second candidate modifier of the C282Y homozygous phenotype. Hum Mol Genet 2004; 13: 1913- 198.
    • (2004) Hum Mol Genet , vol.13 , pp. 1913-1198
    • Le Gac, G.1    Scotet, V.2    Ka, C.3    Gourlaouen, I.4    Bryckaert, L.5    Jacolot, S.6
  • 14
    • 35349002878 scopus 로고    scopus 로고
    • Common variants in the BMP2, BMP4, and HJV genes of the hepcidin regulation pathway modulate HFE hemochromatosis penetrance
    • Milet J, Dehais V, Bourgain C, Jouanolle AM, Mosser A, Perrin M, et al. Common variants in the BMP2, BMP4, and HJV genes of the hepcidin regulation pathway modulate HFE hemochromatosis penetrance. Am J Hum Genet 2007; 81: 799- 807.
    • (2007) Am J Hum Genet , vol.81 , pp. 799-807
    • Milet, J.1    Dehais, V.2    Bourgain, C.3    Jouanolle, A.M.4    Mosser, A.5    Perrin, M.6
  • 15
    • 27744575138 scopus 로고    scopus 로고
    • Phenotypic expression in detected C282Y homozygous women depends on body mass index
    • Laine F, Jouannolle AM, Morcet J, Brigand A, Pouchard M, Lafraise B, et al. Phenotypic expression in detected C282Y homozygous women depends on body mass index. J Hepatol 2005; 43: 1055- 1059.
    • (2005) J Hepatol , vol.43 , pp. 1055-1059
    • Laine, F.1    Jouannolle, A.M.2    Morcet, J.3    Brigand, A.4    Pouchard, M.5    Lafraise, B.6
  • 16
    • 33748265283 scopus 로고    scopus 로고
    • Increased adipose tissue expression of hepcidin in severe obesity is independent from diabetes and NASH
    • Bekri S, Gual P, Anty R, Luciani N, Dahman M, Ramesh B, et al. Increased adipose tissue expression of hepcidin in severe obesity is independent from diabetes and NASH. Gastroenterology 2006; 131: 788- 796.
    • (2006) Gastroenterology , vol.131 , pp. 788-796
    • Bekri, S.1    Gual, P.2    Anty, R.3    Luciani, N.4    Dahman, M.5    Ramesh, B.6
  • 17
    • 33845614105 scopus 로고    scopus 로고
    • Increased expression of hepcidin in obese patients: impact on phenotypic expression of hemochromatosis and pathophysiology of dysmetabolic iron overload syndrome
    • Laine F, Deugnier Y. Increased expression of hepcidin in obese patients: impact on phenotypic expression of hemochromatosis and pathophysiology of dysmetabolic iron overload syndrome. Gastroenterology 2006; 131: 2028.
    • (2006) Gastroenterology , vol.131 , pp. 2028
    • Laine, F.1    Deugnier, Y.2
  • 18
    • 0000699902 scopus 로고
    • Iron metabolism; iron stores in man as measured by phlebotomy
    • Haskins D, Stevens AR Jr, Finch S, Finch CA. Iron metabolism; iron stores in man as measured by phlebotomy. J Clin Invest 1952; 31: 543- 547.
    • (1952) J Clin Invest , vol.31 , pp. 543-547
    • Haskins, D.1    Stevens Jr., A.R.2    Finch, S.3    Finch, C.A.4
  • 19
    • 52049097577 scopus 로고    scopus 로고
    • The link between abdominal obesity and the metabolic syndrome
    • Phillips LK, Prins JB. The link between abdominal obesity and the metabolic syndrome. Curr Hypertens Rep 2008; 10: 156- 164.
    • (2008) Curr Hypertens Rep , vol.10 , pp. 156-164
    • Phillips, L.K.1    Prins, J.B.2
  • 20
    • 0019352109 scopus 로고
    • Assessment of liver iron content in 271 patients: a reevaluation of direct and indirect methods
    • Brissot P, Bourel M, Herry D, Verger JP, Messner M, Beaumont C, et al. Assessment of liver iron content in 271 patients: a reevaluation of direct and indirect methods. Gastroenterology 1981; 80: 557- 565.
    • (1981) Gastroenterology , vol.80 , pp. 557-565
    • Brissot, P.1    Bourel, M.2    Herry, D.3    Verger, J.P.4    Messner, M.5    Beaumont, C.6
  • 21
    • 0022656390 scopus 로고
    • Value of hepatic iron measurements in early hemochromatosis and determination of the critical iron level associated with fibrosis
    • Bassett ML, Halliday JW, Powell LW. Value of hepatic iron measurements in early hemochromatosis and determination of the critical iron level associated with fibrosis. HEPATOLOGY 1986; 6: 24- 29.
    • (1986) HEPATOLOGY , vol.6 , pp. 24-29
    • Bassett, M.L.1    Halliday, J.W.2    Powell, L.W.3
  • 22
    • 34648836734 scopus 로고    scopus 로고
    • Pathology of hepatic iron overload
    • Deugnier Y, Turlin B. Pathology of hepatic iron overload. World J Gastroenterol 2007; 13: 4755- 4760.
    • (2007) World J Gastroenterol , vol.13 , pp. 4755-4760
    • Deugnier, Y.1    Turlin, B.2
  • 25
    • 0029114747 scopus 로고
    • Regulation of ferritin expression by alcohol in a human hepatoblastoma cell line and in rat hepatocyte cultures
    • Moirand R, Kerdavid F, Loreal O, Hubert N, Leroyer P, Brissot P, et al. Regulation of ferritin expression by alcohol in a human hepatoblastoma cell line and in rat hepatocyte cultures. J Hepatol 1995; 23: 431- 439.
    • (1995) J Hepatol , vol.23 , pp. 431-439
    • Moirand, R.1    Kerdavid, F.2    Loreal, O.3    Hubert, N.4    Leroyer, P.5    Brissot, P.6
  • 26
    • 6944237757 scopus 로고    scopus 로고
    • Adipokines: inflammation and the pleiotropic role of white adipose tissue
    • Trayhurn P, Wood IS. Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br J Nutr 2004; 92: 347- 355.
    • (2004) Br J Nutr , vol.92 , pp. 347-355
    • Trayhurn, P.1    Wood, I.S.2
  • 28
    • 35848934560 scopus 로고    scopus 로고
    • Leptin increases the expression of the iron regulatory hormone hepcidin in HuH7 human hepatoma cells
    • Chung B, Matak P, McKie AT, Sharp P. Leptin increases the expression of the iron regulatory hormone hepcidin in HuH7 human hepatoma cells. J Nutr 2007; 137: 2366- 2370.
    • (2007) J Nutr , vol.137 , pp. 2366-2370
    • Chung, B.1    Matak, P.2    McKie, A.T.3    Sharp, P.4
  • 29
    • 33751175421 scopus 로고    scopus 로고
    • Interleukin-6 induces hepcidin expression through STAT3
    • Wrighting DM, Andrews NC. Interleukin-6 induces hepcidin expression through STAT3. Blood 2006; 108: 3204- 3209.
    • (2006) Blood , vol.108 , pp. 3204-3209
    • Wrighting, D.M.1    Andrews, N.C.2
  • 33
    • 47249153165 scopus 로고    scopus 로고
    • Adiposity in women and children from transition countries predicts decreased iron absorption, iron deficiency and a reduced response to iron fortification
    • Zimmermann MB, Zeder C, Muthayya S, Winichagoon P, Chaouki N, Aeberli I, et al. Adiposity in women and children from transition countries predicts decreased iron absorption, iron deficiency and a reduced response to iron fortification. Int J Obes (Lond) 2008; 32: 1098- 1104.
    • (2008) Int J Obes (Lond) , vol.32 , pp. 1098-1104
    • Zimmermann, M.B.1    Zeder, C.2    Muthayya, S.3    Winichagoon, P.4    Chaouki, N.5    Aeberli, I.6
  • 35
    • 62649165515 scopus 로고    scopus 로고
    • Gender differences in insulin resistance, body composition, and energy balance
    • Geer EB, Shen W. Gender differences in insulin resistance, body composition, and energy balance. Gend Med 2009; 6( Suppl 1): 60- 75.
    • (2009) Gend Med , vol.6 , Issue.SUPPL 1 , pp. 60-75
    • Geer, E.B.1    Shen, W.2
  • 36
    • 27744513348 scopus 로고    scopus 로고
    • Estrogen regulation of adiposity and fuel partitioning. Evidence of genomic and non-genomic regulation of lipogenic and oxidative pathways
    • D'Eon TM, Souza SC, Aronovitz M, Obin MS, Fried SK, Greenberg AS. Estrogen regulation of adiposity and fuel partitioning. Evidence of genomic and non-genomic regulation of lipogenic and oxidative pathways. J Biol Chem 2005; 280: 35983- 35991.
    • (2005) J Biol Chem , vol.280 , pp. 35983-35991
    • D'Eon, T.M.1    Souza, S.C.2    Aronovitz, M.3    Obin, M.S.4    Fried, S.K.5    Greenberg, A.S.6
  • 37
    • 65649117326 scopus 로고    scopus 로고
    • Identification of centrarchid hepcidins and evidence that 17beta-estradiol disrupts constitutive expression of hepcidin-1 and inducible expression of hepcidin-2 in largemouth bass (Micropterus salmoides)
    • Robertson LS, Iwanowicz LR, Marranca JM. Identification of centrarchid hepcidins and evidence that 17beta-estradiol disrupts constitutive expression of hepcidin-1 and inducible expression of hepcidin-2 in largemouth bass (Micropterus salmoides). Fish Shellfish Immunol 2009; 26: 898- 907.
    • (2009) Fish Shellfish Immunol , vol.26 , pp. 898-907
    • Robertson, L.S.1    Iwanowicz, L.R.2    Marranca, J.M.3
  • 39
    • 0017893756 scopus 로고
    • Effect of obesity on conversion of plasma androstenedione to estrone in postmenopausal women with and without endometrial cancer
    • MacDonald PC, Edman CD, Hemsell DL, Porter JC, Siiteri PK. Effect of obesity on conversion of plasma androstenedione to estrone in postmenopausal women with and without endometrial cancer. Am J Obstet Gynecol 1978; 130: 448- 455.
    • (1978) Am J Obstet Gynecol , vol.130 , pp. 448-455
    • MacDonald, P.C.1    Edman, C.D.2    Hemsell, D.L.3    Porter, J.C.4    Siiteri, P.K.5
  • 40
    • 0036130293 scopus 로고    scopus 로고
    • The role of cytokines in regulating estrogen synthesis: implications for the etiology of breast cancer
    • Purohit A, Newman SP, Reed MJ. The role of cytokines in regulating estrogen synthesis: implications for the etiology of breast cancer. Breast Cancer Res 2002; 4: 65- 69.
    • (2002) Breast Cancer Res , vol.4 , pp. 65-69
    • Purohit, A.1    Newman, S.P.2    Reed, M.J.3
  • 41
    • 33645813684 scopus 로고    scopus 로고
    • Systemically administered bone morphogenetic protein-6 restores bone in aged ovariectomized rats by increasing bone formation and suppressing bone resorption
    • Simic P, Culej JB, Orlic I, Grgurevic L, Draca N, Spaventi R, et al. Systemically administered bone morphogenetic protein-6 restores bone in aged ovariectomized rats by increasing bone formation and suppressing bone resorption. J Biol Chem 2006; 281: 25509- 25521.
    • (2006) J Biol Chem , vol.281 , pp. 25509-25521
    • Simic, P.1    Culej, J.B.2    Orlic, I.3    Grgurevic, L.4    Draca, N.5    Spaventi, R.6


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