Inactivation of the CovR/S Virulence Regulator Impairs Infection in an Improved Murine Model of Streptococcus pyogenes Naso-Pharyngeal Infection

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Alam, Faraz M ^a   Turner, Claire E ^a   Smith, Ken ^b   Wiles, Siouxsie ^a,c   Sriskandan, Shiranee ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b ROYAL VETERINARY COLLEGE   (United Kingdom)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL MUTATION; BACTERIAL PHENOMENA AND FUNCTIONS; BACTERIAL SHEDDING; BACTERIAL STRAIN; BACTERIAL TRANSMISSION; BACTERIAL VIRULENCE; BACTERIUM CARRIER; CONTROLLED STUDY; FEMALE; GROUP A STREPTOCOCCAL INFECTION; MALE; MOUSE STRAIN; NONHUMAN; RHINOPHARYNGITIS; SEX DIFFERENCE; STRAIN DIFFERENCE; TWO COMPONENT REGULATORY SYSTEM COVRS; AGING; ANIMAL; ANTAGONISTS AND INHIBITORS; DISEASE MODEL; GENETICS; HUMAN; METABOLISM; MICROBIOLOGY; MOUSE; MUTATION; NASOPHARYNX; PATHOPHYSIOLOGY; PHYSIOLOGY; SEXUAL DEVELOPMENT; SPECIES DIFFERENCE; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PYOGENES; TIME; TRANSMISSION;

ANIMALIA; BACTERIA (MICROORGANISMS); MURINAE; NASO; STREPTOCOCCUS PYOGENES;

BACTERIAL PROTEIN; COVS PROTEIN, STREPTOCOCCUS PYOGENES; CSRR PROTEIN, STREPTOCOCCUS PYOGENES; REPRESSOR PROTEIN; SIGNAL PEPTIDE;

AGING; ANIMALS; BACTERIAL PROTEINS; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MUTATION; NASOPHARYNX; REPRESSOR PROTEINS; SEX CHARACTERISTICS; SPECIES SPECIFICITY; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS PYOGENES; TIME FACTORS;

EID: 84876742772     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061655     Document Type: Article

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