Casticin induces caspase-mediated apoptosis via activation of mitochondrial pathway and upregulation of DR5 in human lung cancer cells

Asian Pacific Journal of Tropical Medicine

Volumn 6, Issue 5, 2013, Pages 372-378

  Zhou, Yuan ^a   Peng, Yi ^b   Mao, Qi Qi ^b   Li, Xia ^b   Chen, Ming Wu ^b   Su, Jing ^b   Tian, Li ^a   Mao, Nai Quan ^b   Long, Ling Zhi ^a   Quan, Mei Fang ^a   Liu, Fei ^a   Zhou, Su Fang ^b   Zhao, Yong Xiang ^b  

^a HUNAN NORMAL UNIVERSITY   (China)

^b GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Casticin; Cytochrome c; DR5; Lung cancer; P53

Indexed keywords

ANTINEOPLASTIC AGENT; BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CASPASE 3; CASPASE 8; CASPASE 9; CASTICIN; CYTOCHROME C; DNA FRAGMENT; HLA DR4 ANTIGEN; HLA DR5 ANTIGEN; PROCASPASE 3; PROCASPASE 9; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; PROTEIN P53; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

AGAR GEL ELECTROPHORESIS; ANTIGEN EXPRESSION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER GROWTH; CELL ASSAY; CELL FRACTIONATION; CHIMERA; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LUNG CANCER; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN SECRETION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; UPREGULATION; WESTERN BLOTTING;

APOPTOSIS; CARCINOMA, NON-SMALL-CELL LUNG; CASPASES; CELL LINE, TUMOR; CELL SURVIVAL; CYTOCHROMES C; FLAVONOIDS; HUMANS; LUNG NEOPLASMS; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84876732672     PISSN: 19957645     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1995-7645(13)60041-3     Document Type: Article

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