The antidepressant-like effect of physical activity on a voluntary running wheel

Medicine and Science in Sports and Exercise

Volumn 45, Issue 5, 2013, Pages 851-859

  Cunha, Mauricio P ^a   Oliveira, Ágatha ^a   Pazini, Francis L ^a   Machado, Daniele G ^a   Bettio, Luis E B ^a   Budni, Josiane ^a   Aguiar, Aderbal S ^a   Martins, Daniel F ^a   Santos, Adair R S ^a   Rodrigues, Ana Lúcia S ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; DRUG DERIVATIVE; ISOQUINOLINE DERIVATIVE; N (2 (4 BROMOCINNAMYLAMINO)ETHYL) 5 ISOQUINOLINESULFONAMIDE; N-(2-(4-BROMOCINNAMYLAMINO)ETHYL)-5-ISOQUINOLINESULFONAMIDE; PROTEIN KINASE INHIBITOR; SULFONAMIDE;

ANIMAL; ANIMAL EXPERIMENT; ARTICLE; IMMOBILIZATION; MALE; MOUSE; PHYSIOLOGY; PSYCHOLOGICAL ASPECT;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; HINDLIMB SUSPENSION; ISOQUINOLINES; MALE; MICE; PHYSICAL CONDITIONING, ANIMAL; PROTEIN KINASE INHIBITORS; SULFONAMIDES;

EID: 84876718597     PISSN: 01959131     EISSN: 15300315     Source Type: Journal    
DOI: 10.1249/MSS.0b013e31827b23e6     Document Type: Article

References (36)

1. Akhavan MM, Emami-Abarghoie M, Sadighi-Moghaddam B, Safari M, Yousefi Y, Rashidy-Pour A. Hippocampal angiotensin II receptors play an important role in mediating the effect of voluntary exercise on learning and memory in rat. Brain Res. 2009; 1232:132-8.
2. Almeida RC, Souza DG, Soletti RC, Lo'pez MG, Rodrigues ALS, Gabilan NH. Involvement of PKA, MAPK/ERK and CaMKII, but not PKC in the acute antidepressant-like effect of memantine in mice. Neurosci Lett. 2006;395:93-7.
3. Blendy JA. The role of CREB in depression and antidepressant treatment. Biol Psychiatry. 2006;59:1144-50.
4. Bracski P, Palucha A, Szewczyk B, Wierocska JM, Pilc A, Nowak G. Antidepressant-like activity of 8-Br-cAMP, a PKA activator, in the forced swim test. J Neural Transm. 2008;115:829-30.
5. Caspersen CJ, Powell KE, Christenson GM. Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research. Public Health Rep. 1985;100:126-31.
6. Chaouloff F. Physical exercise and brain monoamines: a review. Acta Physiol Scand. 1989;137:1-13.
7. Charney DS. Monoamine dysfunction and the pathophysiology and treatment of depression. J Clin Psychiatry. 1998;14:11-4.
8. Chijiwa T, Mishima A, Hagiwara M, et al. Inhibition of forskolininduced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino) ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells. J Biol Chem. 1990;265: 5267-72.
9. Cinquanta M, Frittoli E, Mennini T, Gobbi M. Further evidence of Ca2+-dependent, exocytotic-like serotonin release induced by D-fenfluramine. Pharmacol Res. 1997;35:439-42.
10. Dimeo F, Bauer M, Varahram I, Proest G, Halter U. Benefits from aerobic exercise in patients with major depression: a pilot study. Br J Sports Med. 2001;35:114-7.
11. Ding Q, Ying Z, Go'mez-Pinilla F. Exercise influences hippocampal plasticity by modulating brain-derived neurotrophic factor processing. Neuroscience. 2011;192:773-80.
12. Dishman RK, Renner KJ, Youngstedt SD, et al. Activity wheel running reduces escape latency and alters brain monoamine levels after footshock. Brain Res Bull. 1997;42:399-406.
13. Duman CH, Schlesinger L, Russell DS, Duman RS. Voluntary exercise produces antidepressant and anxiolytic behavioral effects in mice. Brain Res. 2008;1199:148-58.
14. Frazer A, Benmansour S. Delayed pharmacological effects of antidepressants. Mol Psychiatry. 2002;7:S23-8.
15. Greenwood BN, Foley TE, Burhans D, Maier SF, Fleshner M. The consequences of uncontrollable stress are sensitive to duration of prior wheel running. Brain Res. 2005a;1033:164-78.
16. Greenwood BN, Foley TE, Day HE, et al. Wheel running alters serotonin (5-HT) transporter, 5-HT1A, 5-HT1B, and alpha1badrenergic receptor mRNA in the rat raphe nuclei. Biol Psychiatry. 2005b;57:559-68.
17. Greenwood BN, Strong PV, Dorey AA, Fleshner M. Therapeutic effects of exercise: wheel running reverses stress-induced interference with shuttle box escape. Behav Neurosci. 2007;121: 992-1000.
18. Hayes K, Sprague S, Guo M, et al. Forced, not voluntary, exercise effectively induces neuroprotection in stroke. Acta Neuropathol. 2008;115:289-96.
19. Machado DG, Bettio LE, Cunha MP, et al. Antidepressant-like effect of rutin isolated from the ethanolic extract from Schinus molle L. in mice: evidence for the involvement of the serotonergic and noradrenergic systems. Eur J Pharmacol. 2008;587:163-8.
20. Mayorga AJ, Dalvi A, Page ME, Zimov-Levinson S, Hen R, Lucki I. Antidepressant-like behavioral effects in 5-hydroxytryptamine 1A and 5-hydroxytryptamine 1B receptor mutant mice. J Pharmacol Exp Ther. 2001;298:1101-7.
21. Miller HL, Delgado PL, Salomon RM, et al. Clinical and biochemical effects of catecholamine depletion on antidepressant-induced remission of depression. Arch Gen Psychiatry. 1996b;53:117-28.
22. Molteni R, Ying Z, Go'mez-Pinilla F. Differential effects of acute and chronic exercise on plasticity-related genes in the rat hippocampus revealed by microarray. Eur J Neurosci. 2002;16:1107-16.
23. Murray CJ, Lopez AD. Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study. Lancet. 1997;349:1436-42.
24. Nibuya M, Nestler EJ, Duman RS. Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus. J Neurosci. 1996;16: 2365-72.
25. Paffenbarger RS, Lee IM, Leung R. Physical activity and personal characteristics associated with depression and suicide in American college men. Acta Psychiatrica Scandinavica. 1994;377:16-22.
26. Page ME, Detke MJ, Dalvi A, Kirby LG, Lucki I. Serotonergic mediation of the effects of fluoxetine, but not desipramine, in the rat forced swimming test. Psychopharmacology. 1999;147:162-7.
27. Popoli M, Brunello N, Perez J, Racagni G. Second messengerregulated protein kinases in the brain: their functional role and the action of antidepressant drugs. J Neurochem. 2000;74:21-33.
28. Porsolt RD, Bertin A, Jalfre M. Behavioral despair in mice: a primary screening test for antidepressants. Arch Int Pharmacodyn Ther. 1977;229:327-36.
29. Redrobe JP, Bourin M, Colombel MC, Baker GB. Dose-dependent noradrenergic and serotonergic properties of venlafaxine in animal models indicative of antidepressant activity. Psychopharmacology. 1998;138:1-8.
30. Roth DL, Holmes DS. Influence of aerobic exercise training and relaxation training on physical and psychologic health following stressful life events. Psychosom Med. 1987;49:355-65.
31. Rush AJ, Trivedi M, Fava M. Depression, IV: STAR*D Treatment Trial for Depression. Am J Psychiatry. 2003;160:237.
32. Schmidt HD, Duman RS. The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior. Behav Pharmacol. 2007;18:391-418.
33. Steru L, Chermat R, Thierry B, Simon P. The tail suspension test: a new method for screening antidepressants in mice. Psychopharmacology. 1985;85:367-70.
34. Tokumitsu H, Chijiwa T, Hagiwara M, Mizutani A, Terasawa M, Hidaka H. KN-62, 1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl- L-tyrosyl]-4- phenylpiperazine, a specific inhibitor of Ca2+/calmodulindependent protein kinase II. J Biol Chem. 1990;265:4315-20.
35. Trejo JL, Llorens-Marti'n MV, Torres-Alema'n I. The effects of exercise on spatial learning and anxiety-like behavior are mediated by an IGF-I-dependent mechanism related to hippocampal neurogenesis. Mol Cell Neurosci. 2008;37:402-11.
36. Vaynman S, Ying Z, Gomez-Pinilla F. The select action of hippocampal calcium calmodulin protein kinase II in mediating exercise-enhanced cognitive function. Neuroscience. 2007;144: 825-33.