Expression of toll-like receptors in chronic otitis media and cholesteatoma

International Journal of Pediatric Otorhinolaryngology

Volumn 77, Issue 5, 2013, Pages 674-676

  Hirai, Haruka ^a   Kariya, Shin ^a   Okano, Mitsuhiro ^a   Fukushima, Kunihiro ^a   Kataoka, Yuko ^a   Maeda, Yukihide ^a   Nishizaki, Kazunori ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Ear; Infection; Innate immunity; Otitis

Indexed keywords

TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CHOLESTEATOMA; CHRONIC OTITIS MEDIA; CLINICAL ARTICLE; CONTROLLED STUDY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RECEPTOR UPREGULATION; SCHOOL CHILD;

ADOLESCENT; ADULT; AGED; CHILD; CHILD, PRESCHOOL; CHOLESTEATOMA; CHRONIC DISEASE; EAR, MIDDLE; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; OTITIS MEDIA; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; UP-REGULATION; YOUNG ADULT;

EID: 84876713338     PISSN: 01655876     EISSN: 18728464     Source Type: Journal    
DOI: 10.1016/j.ijporl.2013.01.010     Document Type: Article

References (17)

1. Lee Y.C., Kim C., Shim J.S., Byun J.Y., Park M.S., Cha C.I., et al. Toll-like receptors 2 and 4 and their mutations in patients with otitis media and middle ear effusion. Clin. Exp. Otorhinolaryngol. 2008, 1:189-195.
2. Kariya S., Okano M., Fukushima K., Nomiya S., Kataoka Y., Nomiya R., et al. Expression of inflammatory mediators in the otitis media induced by Helicobacter pylori antigen in mice. Clin. Exp. Immunol. 2008, 154:134-140. Erratum in Clin. Exp. Immunol. 154 (2008) 432.
3. Kariya S., Okano M., Aoji K., Kosaka M., Chikumoto E., Hattori H., et al. Role of macrophage migration inhibitory factor in otitis media with effusion in adults. Clin. Diagn. Lab. Immunol. 2003, 10:417-422.
4. Szczepański M., Szyfter W., Jenek R., Wróbel M., Lisewska I.M., Zeromski J. Toll-like receptors 2, 3 and 4 (TLR-2, TLR-3 and TLR-4) are expressed in the microenvironment of human acquired cholesteatoma. Eur. Arch. Otorhinolaryngol. 2006, 263:603-607.
5. Leichtle A., Lai Y., Wollenberg B., Wasserman S.I., Ryan A.F. Innate signaling in otitis media: pathogenesis and recovery. Curr. Allergy Asthma Rep. 2011, 11:78-84.
6. Kopp E., Medzhitov R. Recognition of microbial infection by Toll-like receptors. Curr. Opin. Immunol. 2003, 15:396-401.
7. Prince L.R., Whyte M.K., Sabroe I., Parker L.C. The role of TLRs in neutrophil activation. Curr. Opin. Pharmacol. 2011, 11:397-403.
8. Chen K., Huang J., Gong W., Iribarren P., Dunlop N.M., Wang J.M. Toll-like receptors in inflammation, infection and cancer. Int. Immunopharmacol. 2007, 7:1271-1285.
9. DeMaria T.F., Apicella M.A., Nichols W.A., Leake E.R. Evaluation of the virulence of nontypeable Haemophilus influenzae lipooligosaccharide htrB and rfaD mutants in the chinchilla model of otitis media. Infect. Immun. 1997, 65:4431-4435.
10. Kariya S., Schachern P.A., Cureoglu S., Tsuprun V., Okano M., Nishizaki K., et al. Up-regulation of macrophage migration inhibitory factor induced by endotoxin in experimental otitis media with effusion in mice. Acta Otolaryngol. 2008, 128:750-755.
11. Kariya S., Okano M., Higaki T., Makihara S., Haruna T., Eguchi M., et al. Neutralizing antibody against granulocyte/macrophage colony-stimulating factor inhibits otitis media. Laryngoscope 2012, (November). (Epub ahead of print). 10.1002/lary.23795.
12. Mills K.H. TLR-dependent T cell activation in autoimmunity. Nat. Rev. Immunol. 2011, 11:807-822.
13. Boyd J.H. Toll-like receptors and opportunities for new sepsis therapeutics. Curr. Infect. Dis. Rep. 2012, 14:455-461.
14. Mullarkey M., Rose J.R., Bristol J., Kawata T., Kimura A., Kobayashi S., et al. Inhibition of endotoxin response by e5564, a novel Toll-like receptor 4-directed endotoxin antagonist. J. Pharmacol. Exp. Ther. 2003, 304:1093-1102.
15. Rossignol D.P., Lynn M. TLR4 antagonists for endotoxemia and beyond. Curr. Opin. Investig. Drugs 2005, 6:496-502.
16. Kalil A.C., LaRosa S.P., Gogate J., Lynn M., Opal S.M., Eritoran Sepsis Study Group Influence of severity of illness on the effects of eritoran tetrasodium (E5564) and on other therapies for severe sepsis. Shock 2011, 36:327-331.
17. Si Y., Zhang Z.G., Huang C.Y., He J.F., Feng L.Q., Chen Y.B., et al. Differential expression of toll-like receptors in chronic suppurative otitis media and cholesteatoma. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2012, 47:388-393. (in Chinese).