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Volumn 31, Issue SUPPL2, 2013, Pages

Group A streptococcal vaccines: Paving a path for accelerated development

(12)  Dale, James B a   Fischetti, Vincent A b   Carapetis, Jonathan R c   Steer, Andrew C d   Sow, Samba e   Kumar, Rajesh f   Mayosi, Bongani M g   Rubin, Fran A h   Mulholland, Kim i   Hombach, Joachim Maria j   Schödel, Florian k   Henao Restrepo, Ana Maria j  


Author keywords

Group A streptococci; Rheumatic heart disease; Vaccines

Indexed keywords

STREPTOCOCCUS GROUP A VACCINE; STREPTOCOCCUS VACCINE; UNCLASSIFIED DRUG;

EID: 84876704846     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2012.09.045     Document Type: Review
Times cited : (76)

References (64)
  • 2
    • 32744475683 scopus 로고    scopus 로고
    • Cost-effectiveness analysis of intervention strategies for reduction of the burden of rheumatic heart disease
    • American Registry of Pathology, Washington, DC, Narula Jea (Ed.)
    • Michaud C., Rammohan R., Narula J. Cost-effectiveness analysis of intervention strategies for reduction of the burden of rheumatic heart disease. Rheumatic Fever 1999, 485-497. American Registry of Pathology, Washington, DC. Narula Jea (Ed.).
    • (1999) Rheumatic Fever , pp. 485-497
    • Michaud, C.1    Rammohan, R.2    Narula, J.3
  • 3
    • 84862151705 scopus 로고    scopus 로고
    • Invasive group a streptococcal disease: epidemiology, pathogenesis and management
    • Steer A.C., Lamagni T., Curtis N., Carapetis J.R. Invasive group a streptococcal disease: epidemiology, pathogenesis and management. Drugs 2012, 72(9):1213-1227.
    • (2012) Drugs , vol.72 , Issue.9 , pp. 1213-1227
    • Steer, A.C.1    Lamagni, T.2    Curtis, N.3    Carapetis, J.R.4
  • 4
    • 34547643188 scopus 로고    scopus 로고
    • Prevalence of rheumatic heart disease detected by echocardiographic screening
    • Marijon E., Ou P., Celermajer D.S., Ferreira B., Mocumbi A.O., Jani D., et al. Prevalence of rheumatic heart disease detected by echocardiographic screening. N Engl J Med 2007, 357(5):470-476.
    • (2007) N Engl J Med , vol.357 , Issue.5 , pp. 470-476
    • Marijon, E.1    Ou, P.2    Celermajer, D.S.3    Ferreira, B.4    Mocumbi, A.O.5    Jani, D.6
  • 5
    • 77953122743 scopus 로고    scopus 로고
    • Prevalence of rheumatic heart disease in children and young adults in Nicaragua
    • Paar J.A., Berrios N.M., Rose J.D., Caceres M., Pena R., Perez W., et al. Prevalence of rheumatic heart disease in children and young adults in Nicaragua. Am J Card 2010, 105(12):1809-1814.
    • (2010) Am J Card , vol.105 , Issue.12 , pp. 1809-1814
    • Paar, J.A.1    Berrios, N.M.2    Rose, J.D.3    Caceres, M.4    Pena, R.5    Perez, W.6
  • 6
    • 84863218547 scopus 로고    scopus 로고
    • Echocardiography screening for rheumatic heart disease in Ugandan schoolchildren
    • Beaton A., Okello E., Lwabi P., Mondo C., McCarter R., Sable C. Echocardiography screening for rheumatic heart disease in Ugandan schoolchildren. Circulation 2012, 125(25):3127-3132.
    • (2012) Circulation , vol.125 , Issue.25 , pp. 3127-3132
    • Beaton, A.1    Okello, E.2    Lwabi, P.3    Mondo, C.4    McCarter, R.5    Sable, C.6
  • 7
    • 84876740349 scopus 로고    scopus 로고
    • Standardized protocols for GAS burden estimation. Available from: [cited 05.09.2012]
    • Standardized protocols for GAS burden estimation. Available from: [cited 05.09.2012]. http://www.niaid.nih.gov/TOPICS/STREPTOCOCCAL/Pages/protocols.aspx.
  • 8
    • 84859735554 scopus 로고    scopus 로고
    • World Heart Federation criteria for echocardiographic diagnosis of rheumatic heart disease-an evidence-based guideline
    • Remenyi B., Wilson N., Steer A., Ferreira B., Kado J., Kumar K., et al. World Heart Federation criteria for echocardiographic diagnosis of rheumatic heart disease-an evidence-based guideline. Nat Rev 2012, 9(5):297-309.
    • (2012) Nat Rev , vol.9 , Issue.5 , pp. 297-309
    • Remenyi, B.1    Wilson, N.2    Steer, A.3    Ferreira, B.4    Kado, J.5    Kumar, K.6
  • 9
    • 69549088236 scopus 로고    scopus 로고
    • Rheumatic heart disease screening by echocardiography: the inadequacy of world health organization criteria for optimizing the diagnosis of subclinical disease
    • Marijon E., Celermajer D.S., Tafflet M., El-Haou S., Jani D.N., Ferreira B., et al. Rheumatic heart disease screening by echocardiography: the inadequacy of world health organization criteria for optimizing the diagnosis of subclinical disease. Circulation 2009, 120(8):663-668.
    • (2009) Circulation , vol.120 , Issue.8 , pp. 663-668
    • Marijon, E.1    Celermajer, D.S.2    Tafflet, M.3    El-Haou, S.4    Jani, D.N.5    Ferreira, B.6
  • 10
    • 84876728648 scopus 로고    scopus 로고
    • CDC Streptococcus Laboratory. Available from: [cited 05.09.2012]
    • CDC Streptococcus Laboratory. Available from: [cited 05.09.2012]. http://www.cdc.gov/ncidod/biotech/strep/strepindex.htm.
  • 11
    • 84876705610 scopus 로고    scopus 로고
    • Hilleman Laboratories meeting summary: is a group A streptococcal vaccine desirable and feasible, New Delhi, March 2010. Available from: ; [cited 05.06.2012]
    • Hilleman Laboratories meeting summary: is a group A streptococcal vaccine desirable and feasible, New Delhi, March 2010. Available from: ; 2011 [cited 05.06.2012]. http://www.hillemanlabs.org/pdf/gas-meeting-summary.pdf.
    • (2011)
  • 12
    • 84876709899 scopus 로고    scopus 로고
    • Proceedings of the tenth global vaccine research forum and parallel satellite symposia, Geneva, 26-29 June 2011. Available from: ;[cited 25.05.2012]
    • Proceedings of the tenth global vaccine research forum and parallel satellite symposia, Geneva, 26-29 June 2011. Available from: ; 2012 [cited 25.05.2012]. http://www.who.int/immunization/documents/innovation/WHO_IVB_12.06/en/index.html.
    • (2012)
  • 13
    • 4043125290 scopus 로고    scopus 로고
    • Progress in group A streptococcal vaccine development
    • Kotloff K.L., Dale J.B. Progress in group A streptococcal vaccine development. Pediatr Infect Dis J 2004, 23(8):765-766.
    • (2004) Pediatr Infect Dis J , vol.23 , Issue.8 , pp. 765-766
    • Kotloff, K.L.1    Dale, J.B.2
  • 14
    • 0014266010 scopus 로고
    • Secondary and apparent primary antibody responses after group A streptococcal vaccination of 21 children
    • Massell B.F., Michael J.G., Amezcua J., Siner M. Secondary and apparent primary antibody responses after group A streptococcal vaccination of 21 children. Appl Microbiol 1968, 16(3):509-518.
    • (1968) Appl Microbiol , vol.16 , Issue.3 , pp. 509-518
    • Massell, B.F.1    Michael, J.G.2    Amezcua, J.3    Siner, M.4
  • 15
    • 0014669387 scopus 로고
    • Rheumatic fever following streptococcal vaccination. Report of three cases
    • Massell B.F., Honikman L.H., Amezcua J. Rheumatic fever following streptococcal vaccination. Report of three cases. JAMA 1969, 207(6):1115-1119.
    • (1969) JAMA , vol.207 , Issue.6 , pp. 1115-1119
    • Massell, B.F.1    Honikman, L.H.2    Amezcua, J.3
  • 16
    • 3843094971 scopus 로고    scopus 로고
    • Safety and immunogenicity of a recombinant multivalent group a streptococcal vaccine in healthy adults: phase 1 trial
    • Kotloff K.L., Corretti M., Palmer K., Campbell J.D., Reddish M.A., Hu M.C., et al. Safety and immunogenicity of a recombinant multivalent group a streptococcal vaccine in healthy adults: phase 1 trial. JAMA 2004, 292(6):709-715.
    • (2004) JAMA , vol.292 , Issue.6 , pp. 709-715
    • Kotloff, K.L.1    Corretti, M.2    Palmer, K.3    Campbell, J.D.4    Reddish, M.A.5    Hu, M.C.6
  • 17
    • 26444487581 scopus 로고    scopus 로고
    • Safety and immunogenicity of 26-valent group A streptococcus vaccine in healthy adult volunteers
    • McNeil S.A., Halperin S.A., Langley J.M., Smith B., Warren A., Sharratt G.P., et al. Safety and immunogenicity of 26-valent group A streptococcus vaccine in healthy adult volunteers. Clin Infect Dis 2005, 41(8):1114-1122.
    • (2005) Clin Infect Dis , vol.41 , Issue.8 , pp. 1114-1122
    • McNeil, S.A.1    Halperin, S.A.2    Langley, J.M.3    Smith, B.4    Warren, A.5    Sharratt, G.P.6
  • 18
    • 33645940620 scopus 로고    scopus 로고
    • A double-blind, randomized, phase II trial of the safety and immunogenicity of 26-valent group A streptococcus vaccine in healthy adults
    • McNeil S., Halperin S., Langley J.M., Smith B., Baxendale D.M., Warren A., et al. A double-blind, randomized, phase II trial of the safety and immunogenicity of 26-valent group A streptococcus vaccine in healthy adults. Int Congr Ser 2005, 1289:303-306.
    • (2005) Int Congr Ser , vol.1289 , pp. 303-306
    • McNeil, S.1    Halperin, S.2    Langley, J.M.3    Smith, B.4    Baxendale, D.M.5    Warren, A.6
  • 19
    • 80053951774 scopus 로고    scopus 로고
    • New 30-valent M protein-based vaccine evokes cross-opsonic antibodies against non-vaccine serotypes of group A streptococci
    • Dale J.B., Penfound T.A., Chiang E.Y., Walton W.J. New 30-valent M protein-based vaccine evokes cross-opsonic antibodies against non-vaccine serotypes of group A streptococci. Vaccine 2011, 29(46):8175-8178.
    • (2011) Vaccine , vol.29 , Issue.46 , pp. 8175-8178
    • Dale, J.B.1    Penfound, T.A.2    Chiang, E.Y.3    Walton, W.J.4
  • 20
    • 34848846150 scopus 로고    scopus 로고
    • The epidemiology of invasive group A streptococcal infection and potential vaccine implications: United States, 2000-2004
    • O'Loughlin R.E., Roberson A., Cieslak P.R., Lynfield R., Gershman K., Craig A., et al. The epidemiology of invasive group A streptococcal infection and potential vaccine implications: United States, 2000-2004. Clin Infect Dis 2007, 45(7):853-862.
    • (2007) Clin Infect Dis , vol.45 , Issue.7 , pp. 853-862
    • O'Loughlin, R.E.1    Roberson, A.2    Cieslak, P.R.3    Lynfield, R.4    Gershman, K.5    Craig, A.6
  • 21
    • 65249093620 scopus 로고    scopus 로고
    • Clinical and microbiological characteristics of severe Streptococcus pyogenes disease in Europe
    • Luca-Harari B., Darenberg J., Neal S., Siljander T., Strakova L., Tanna A., et al. Clinical and microbiological characteristics of severe Streptococcus pyogenes disease in Europe. J Clin Microbiol 2009, 47(4):1155-1165.
    • (2009) J Clin Microbiol , vol.47 , Issue.4 , pp. 1155-1165
    • Luca-Harari, B.1    Darenberg, J.2    Neal, S.3    Siljander, T.4    Strakova, L.5    Tanna, A.6
  • 23
    • 78650190051 scopus 로고    scopus 로고
    • Systematic review: estimation of global burden of non-suppurative sequelae of upper respiratory tract infection: rheumatic fever and post-streptococcal glomerulonephritis
    • Jackson S.J., Steer A.C., Campbell H. Systematic review: estimation of global burden of non-suppurative sequelae of upper respiratory tract infection: rheumatic fever and post-streptococcal glomerulonephritis. Trop Med Int Health 2011, 16(1):2-11.
    • (2011) Trop Med Int Health , vol.16 , Issue.1 , pp. 2-11
    • Jackson, S.J.1    Steer, A.C.2    Campbell, H.3
  • 24
    • 84863404115 scopus 로고    scopus 로고
    • Post-streptococcal glomerulonephritis is a strong risk factor for chronic kidney disease in later life
    • Hoy W.E., White A.V., Dowling A., Sharma S.K., Bloomfield H., Tipiloura B.T., et al. Post-streptococcal glomerulonephritis is a strong risk factor for chronic kidney disease in later life. Kidney Int 2012, 81(10):1026-1032.
    • (2012) Kidney Int , vol.81 , Issue.10 , pp. 1026-1032
    • Hoy, W.E.1    White, A.V.2    Dowling, A.3    Sharma, S.K.4    Bloomfield, H.5    Tipiloura, B.T.6
  • 25
    • 70349189311 scopus 로고    scopus 로고
    • Global emm type distribution of group A streptococci: systematic review and implications for vaccine development
    • Steer A.C., Law I., Matatolu L., Beall B.W., Carapetis J.R. Global emm type distribution of group A streptococci: systematic review and implications for vaccine development. Lancet Infect Dis 2009, 9(10):611-616.
    • (2009) Lancet Infect Dis , vol.9 , Issue.10 , pp. 611-616
    • Steer, A.C.1    Law, I.2    Matatolu, L.3    Beall, B.W.4    Carapetis, J.R.5
  • 26
    • 0033805730 scopus 로고    scopus 로고
    • Contrasting molecular epidemiology of group A streptococci causing tropical and nontropical infections of the skin and throat
    • Bessen D.E., Carapetis J.R., Beall B., Katz R., Hibble M., Currie B.J., et al. Contrasting molecular epidemiology of group A streptococci causing tropical and nontropical infections of the skin and throat. J Infect Dis 2000, 182(4):1109-1116.
    • (2000) J Infect Dis , vol.182 , Issue.4 , pp. 1109-1116
    • Bessen, D.E.1    Carapetis, J.R.2    Beall, B.3    Katz, R.4    Hibble, M.5    Currie, B.J.6
  • 27
    • 0036130722 scopus 로고    scopus 로고
    • Immunogenicity of a 26-valent group A streptococcal vaccine
    • Hu M., Walls M., Stroop S., Reddish M., Beall B., Dale J. Immunogenicity of a 26-valent group A streptococcal vaccine. Infect Immun 2002, 70:2171-2177.
    • (2002) Infect Immun , vol.70 , pp. 2171-2177
    • Hu, M.1    Walls, M.2    Stroop, S.3    Reddish, M.4    Beall, B.5    Dale, J.6
  • 28
    • 53449099372 scopus 로고    scopus 로고
    • Genetic diversity of group A streptococcus M protein: implications for typing and vaccine development
    • Smeesters P.R., Mardulyn P., Vergison A., Leplae R., Van Melderen L. Genetic diversity of group A streptococcus M protein: implications for typing and vaccine development. Vaccine 2008, 26(46):5835-5842.
    • (2008) Vaccine , vol.26 , Issue.46 , pp. 5835-5842
    • Smeesters, P.R.1    Mardulyn, P.2    Vergison, A.3    Leplae, R.4    Van Melderen, L.5
  • 29
    • 68549085162 scopus 로고    scopus 로고
    • Emm and C-repeat region molecular typing of beta-hemolytic streptococci in a tropical country: implications for vaccine development
    • Steer A.C., Magor G., Jenney A.W., Kado J., Good M.F., McMillan D., et al. emm and C-repeat region molecular typing of beta-hemolytic streptococci in a tropical country: implications for vaccine development. J Clin Microbiol 2009, 47(8):2502-2509.
    • (2009) J Clin Microbiol , vol.47 , Issue.8 , pp. 2502-2509
    • Steer, A.C.1    Magor, G.2    Jenney, A.W.3    Kado, J.4    Good, M.F.5    McMillan, D.6
  • 30
    • 66949121371 scopus 로고    scopus 로고
    • Seven-year surveillance of North American pediatric group a streptococcal pharyngitis isolates
    • Shulman S.T., Tanz R.R., Dale J.B., Beall B., Kabat W., Kabat K., et al. Seven-year surveillance of North American pediatric group a streptococcal pharyngitis isolates. Clin Infect Dis 2009, 49(1):78-84.
    • (2009) Clin Infect Dis , vol.49 , Issue.1 , pp. 78-84
    • Shulman, S.T.1    Tanz, R.R.2    Dale, J.B.3    Beall, B.4    Kabat, W.5    Kabat, K.6
  • 31
    • 0023683255 scopus 로고
    • Influence of intranasal immunization with synthetic peptides corresponding to conserved epitopes of M protein on mucosal colonization by group A streptococci
    • Bessen D., Fischetti V.A. Influence of intranasal immunization with synthetic peptides corresponding to conserved epitopes of M protein on mucosal colonization by group A streptococci. Infect Immun 1988, 56:2666-2672.
    • (1988) Infect Immun , vol.56 , pp. 2666-2672
    • Bessen, D.1    Fischetti, V.A.2
  • 32
    • 0026599288 scopus 로고
    • Epitopes of group A streptococcal M protein that evoke cross-protective local immune responses
    • Bronze M.S., Courtney H.S., Dale J.B. Epitopes of group A streptococcal M protein that evoke cross-protective local immune responses. J Immunol 1992, 148:888-893.
    • (1992) J Immunol , vol.148 , pp. 888-893
    • Bronze, M.S.1    Courtney, H.S.2    Dale, J.B.3
  • 33
    • 3442902224 scopus 로고    scopus 로고
    • Preclinical evaluation of a vaccine based on conserved region of M protein that prevents group A streptococcal infection
    • Batzloff M., Yan H., Davies M., Hartas J., Good M. Preclinical evaluation of a vaccine based on conserved region of M protein that prevents group A streptococcal infection. Indian J Med Res 2004, 119Suppl:104-107.
    • (2004) Indian J Med Res , vol.119 Suppl , pp. 104-107
    • Batzloff, M.1    Yan, H.2    Davies, M.3    Hartas, J.4    Good, M.5
  • 34
    • 0038583522 scopus 로고    scopus 로고
    • Protection against group A streptococcus by immunization with J8-diphtheria toxoid: contribution of J8- and diphtheria toxoid-specific antibodies to protection
    • Batzloff M.R., Hayman W.A., Davies M.R., Zeng M., Pruksakorn S., Brandt E.R., et al. Protection against group A streptococcus by immunization with J8-diphtheria toxoid: contribution of J8- and diphtheria toxoid-specific antibodies to protection. J Infect Dis 2003, 187(10):1598-1608.
    • (2003) J Infect Dis , vol.187 , Issue.10 , pp. 1598-1608
    • Batzloff, M.R.1    Hayman, W.A.2    Davies, M.R.3    Zeng, M.4    Pruksakorn, S.5    Brandt, E.R.6
  • 35
    • 77954757546 scopus 로고    scopus 로고
    • Protective efficacy of group A streptococcal vaccines containing type-specific and conserved M protein epitopes
    • Penfound T., Chiang E., Ahmed E., Dale J. Protective efficacy of group A streptococcal vaccines containing type-specific and conserved M protein epitopes. Vaccine 2010, 28(31):5017-5022.
    • (2010) Vaccine , vol.28 , Issue.31 , pp. 5017-5022
    • Penfound, T.1    Chiang, E.2    Ahmed, E.3    Dale, J.4
  • 36
    • 79955390762 scopus 로고    scopus 로고
    • Global research priorities in rheumatic fever and rheumatic heart disease
    • Carapetis J.R., Zuhlke L.J. Global research priorities in rheumatic fever and rheumatic heart disease. Ann Pediat Cardiol 2011, 4(1):4-12.
    • (2011) Ann Pediat Cardiol , vol.4 , Issue.1 , pp. 4-12
    • Carapetis, J.R.1    Zuhlke, L.J.2
  • 37
    • 33947408802 scopus 로고    scopus 로고
    • Proteomic analysis and identification of Streptococcus pyogenes surface-associated proteins
    • Severin A., Nickbarg E., Wooters J., Quazi S.A., Matsuka Y.V., Murphy E., et al. Proteomic analysis and identification of Streptococcus pyogenes surface-associated proteins. J Bacteriol 2007, 189(5):1514-1522.
    • (2007) J Bacteriol , vol.189 , Issue.5 , pp. 1514-1522
    • Severin, A.1    Nickbarg, E.2    Wooters, J.3    Quazi, S.A.4    Matsuka, Y.V.5    Murphy, E.6
  • 38
    • 32344453260 scopus 로고    scopus 로고
    • Characterization and identification of vaccine candidate proteins through analysis of the group A Streptococcus surface proteome
    • Rodriguez-Ortega M.J., Norais N., Bensi G., Liberatori S., Capo S., Mora M., et al. Characterization and identification of vaccine candidate proteins through analysis of the group A Streptococcus surface proteome. Nat Biotechnol 2006, 24(2):191-197.
    • (2006) Nat Biotechnol , vol.24 , Issue.2 , pp. 191-197
    • Rodriguez-Ortega, M.J.1    Norais, N.2    Bensi, G.3    Liberatori, S.4    Capo, S.5    Mora, M.6
  • 39
    • 77956629138 scopus 로고    scopus 로고
    • Novel conserved group A streptococcal proteins identified by the antigenome technology as vaccine candidates for a non-M protein-based vaccine
    • Fritzer A., Senn B.M., Minh D.B., Hanner M., Gelbmann D., Noiges B., et al. Novel conserved group A streptococcal proteins identified by the antigenome technology as vaccine candidates for a non-M protein-based vaccine. Infect Immun 2010, 78(9):4051-4067.
    • (2010) Infect Immun , vol.78 , Issue.9 , pp. 4051-4067
    • Fritzer, A.1    Senn, B.M.2    Minh, D.B.3    Hanner, M.4    Gelbmann, D.5    Noiges, B.6
  • 42
  • 43
    • 9244254775 scopus 로고    scopus 로고
    • Intranasal vaccination with streptococcal fibronectin binding protein Sfb1 fails to prevent growth and dissemination of Streptococcus pyogenes in a murine skin infection model
    • McArthur J., Medina E., Mueller A., Chin J., Currie B.J., Sriprakash K.S., et al. Intranasal vaccination with streptococcal fibronectin binding protein Sfb1 fails to prevent growth and dissemination of Streptococcus pyogenes in a murine skin infection model. Infect Immun 2004, 72(12):7342-7345.
    • (2004) Infect Immun , vol.72 , Issue.12 , pp. 7342-7345
    • McArthur, J.1    Medina, E.2    Mueller, A.3    Chin, J.4    Currie, B.J.5    Sriprakash, K.S.6
  • 44
    • 33744973798 scopus 로고    scopus 로고
    • Group A streptococcal infections of the skin: molecular advances but limited therapeutic progress
    • Currie B.J. Group A streptococcal infections of the skin: molecular advances but limited therapeutic progress. Curr Opin Infect Dis 2006, 19(2):132-138.
    • (2006) Curr Opin Infect Dis , vol.19 , Issue.2 , pp. 132-138
    • Currie, B.J.1
  • 45
    • 84858006447 scopus 로고    scopus 로고
    • Streptococcal skin infection and rheumatic heart disease
    • Parks T., Smeesters P.R., Steer A.C. Streptococcal skin infection and rheumatic heart disease. Curr Opin Infect Dis 2012, 25(2):145-153.
    • (2012) Curr Opin Infect Dis , vol.25 , Issue.2 , pp. 145-153
    • Parks, T.1    Smeesters, P.R.2    Steer, A.C.3
  • 46
    • 84876706375 scopus 로고    scopus 로고
    • Sixty-fifth World Health Assembly. Available from: [cited 05.09.2012].
    • Sixty-fifth World Health Assembly. Available from: [cited 05.09.2012]. http://www.who.int/mediacentre/events/2012/wha65/en/index.html.
  • 48
    • 84857355393 scopus 로고    scopus 로고
    • Evaluation of novel Streptococcus pyogenes vaccine candidates incorporating multiple conserved sequences from the C-repeat region of the M-protein
    • Bauer M.J., Georgousakis M.M., Vu T., Henningham A., Hofmann A., Rettel M., et al. Evaluation of novel Streptococcus pyogenes vaccine candidates incorporating multiple conserved sequences from the C-repeat region of the M-protein. Vaccine 2012, 30(12):2197-2205.
    • (2012) Vaccine , vol.30 , Issue.12 , pp. 2197-2205
    • Bauer, M.J.1    Georgousakis, M.M.2    Vu, T.3    Henningham, A.4    Hofmann, A.5    Rettel, M.6
  • 49
    • 29744463674 scopus 로고    scopus 로고
    • Group A streptococcus (GAS) carbohydrate as an immunogen for protection against GAS infection
    • Sabharwal H., Michon F., Nelson D., Dong W., Fuchs K., Manjarrez R.C., et al. Group A streptococcus (GAS) carbohydrate as an immunogen for protection against GAS infection. J Infect Dis 2006, 193(1):129-135.
    • (2006) J Infect Dis , vol.193 , Issue.1 , pp. 129-135
    • Sabharwal, H.1    Michon, F.2    Nelson, D.3    Dong, W.4    Fuchs, K.5    Manjarrez, R.C.6
  • 51
    • 0141840769 scopus 로고    scopus 로고
    • Immune response to group A streptococcal C5a peptidase in children: implications for vaccine development
    • Shet A., Kaplan E.L., Johnson D.R., Cleary P.P. Immune response to group A streptococcal C5a peptidase in children: implications for vaccine development. J Infect Dis 2003, 188(6):809-817.
    • (2003) J Infect Dis , vol.188 , Issue.6 , pp. 809-817
    • Shet, A.1    Kaplan, E.L.2    Johnson, D.R.3    Cleary, P.P.4
  • 52
    • 0035142610 scopus 로고    scopus 로고
    • Systemic and mucosal immunizations with fibronectin-binding protein FBP54 induce protective immune responses against Streptococcus pyogenes challenge in mice
    • Kawabata S., Kunitomo E., Terao Y., Nakagawa I., Kikuchi K., Totsuka K., et al. Systemic and mucosal immunizations with fibronectin-binding protein FBP54 induce protective immune responses against Streptococcus pyogenes challenge in mice. Infect Immun 2001, 69(2):924-930.
    • (2001) Infect Immun , vol.69 , Issue.2 , pp. 924-930
    • Kawabata, S.1    Kunitomo, E.2    Terao, Y.3    Nakagawa, I.4    Kikuchi, K.5    Totsuka, K.6
  • 53
    • 0041322724 scopus 로고    scopus 로고
    • Serum opacity factor (SOF) of Streptococcus pyogenes evokes antibodies that opsonize homologous and heterologous SOF-positive serotypes of group A streptococci
    • Courtney H.S., Hasty D.L., Dale J.B. Serum opacity factor (SOF) of Streptococcus pyogenes evokes antibodies that opsonize homologous and heterologous SOF-positive serotypes of group A streptococci. Infect Immun 2003, 71(9):5097-5103.
    • (2003) Infect Immun , vol.71 , Issue.9 , pp. 5097-5103
    • Courtney, H.S.1    Hasty, D.L.2    Dale, J.B.3
  • 54
    • 32344435599 scopus 로고    scopus 로고
    • Intranasal immunization with serum opacity factor (SOF) of Streptococcus pyogenes fails to protect mice against lethal mucosal challenge with a heterologous strain
    • Schulze K., Medina E., Guzman C.A. Intranasal immunization with serum opacity factor (SOF) of Streptococcus pyogenes fails to protect mice against lethal mucosal challenge with a heterologous strain. Vaccine 2006, 24(9):1446-1450.
    • (2006) Vaccine , vol.24 , Issue.9 , pp. 1446-1450
    • Schulze, K.1    Medina, E.2    Guzman, C.A.3
  • 55
    • 0027931766 scopus 로고
    • Vaccination with streptococcal extracellular cysteine protease (interleukin 1B convertase) protects mice against challenge with heterologous group A streptococci
    • Kapur V., Maffei J.T., Greer R.S., Li L.L., Adams G.J., Musser J.M. Vaccination with streptococcal extracellular cysteine protease (interleukin 1B convertase) protects mice against challenge with heterologous group A streptococci. Microb Pathogen 1994, 16:443.
    • (1994) Microb Pathogen , vol.16 , pp. 443
    • Kapur, V.1    Maffei, J.T.2    Greer, R.S.3    Li, L.L.4    Adams, G.J.5    Musser, J.M.6
  • 56
    • 0034663767 scopus 로고    scopus 로고
    • Development of streptococcal pyrogenic exotoxin C vaccine toxoids that are protective in the rabbit model of toxic shock syndrome
    • McCormick J.K., Tripp T.J., Olmsted S.B., Matsuka Y.V., Gahr P.J., Ohlendorf D.H., et al. Development of streptococcal pyrogenic exotoxin C vaccine toxoids that are protective in the rabbit model of toxic shock syndrome. J Immunol 2000, 165(4):2306-2312.
    • (2000) J Immunol , vol.165 , Issue.4 , pp. 2306-2312
    • McCormick, J.K.1    Tripp, T.J.2    Olmsted, S.B.3    Matsuka, Y.V.4    Gahr, P.J.5    Ohlendorf, D.H.6
  • 57
    • 77950463574 scopus 로고    scopus 로고
    • Typing of the pilus-protein-encoding FCT region and biofilm formation as novel parameters in epidemiological investigations of Streptococcus pyogenes isolates from various infection sites
    • Koller T., Manetti A.G., Kreikemeyer B., Lembke C., Margarit I., Grandi G., et al. Typing of the pilus-protein-encoding FCT region and biofilm formation as novel parameters in epidemiological investigations of Streptococcus pyogenes isolates from various infection sites. J Med Microbiol 2011, 59(Pt 4):442-452.
    • (2011) J Med Microbiol , vol.59 , Issue.PART 4 , pp. 442-452
    • Koller, T.1    Manetti, A.G.2    Kreikemeyer, B.3    Lembke, C.4    Margarit, I.5    Grandi, G.6
  • 58
    • 77955816649 scopus 로고    scopus 로고
    • Streptococcus pyogenes SpyCEP: a chemokine-inactivating protease with unique structural and biochemical features
    • Zingaretti C., Falugi F., Nardi-Dei V., Pietrocola G., Mariani M., Liberatori S., et al. Streptococcus pyogenes SpyCEP: a chemokine-inactivating protease with unique structural and biochemical features. FASEB J 2010.
    • (2010) FASEB J
    • Zingaretti, C.1    Falugi, F.2    Nardi-Dei, V.3    Pietrocola, G.4    Mariani, M.5    Liberatori, S.6
  • 59
    • 34447280868 scopus 로고    scopus 로고
    • Active and passive immunizations with the streptococcal esterase Sse protect mice against subcutaneous infection with group A streptococci
    • Liu M., Zhu H., Zhang J., Lei B. Active and passive immunizations with the streptococcal esterase Sse protect mice against subcutaneous infection with group A streptococci. Infect Immun 2007, 75(7):3651-3657.
    • (2007) Infect Immun , vol.75 , Issue.7 , pp. 3651-3657
    • Liu, M.1    Zhu, H.2    Zhang, J.3    Lei, B.4
  • 60
    • 84876699242 scopus 로고    scopus 로고
    • inventors; Novartis Vaccines and Diagnostics, SRL, assignee. Immunogenic compositions for Streptococcus pyogenes. US.
    • Grandi G, Telford JL, Bensi G, inventors; Novartis Vaccines and Diagnostics, SRL, assignee. Immunogenic compositions for Streptococcus pyogenes. US. 2010.
    • (2010)
    • Grandi, G.1    Telford, J.L.2    Bensi, G.3
  • 61
    • 3142602932 scopus 로고    scopus 로고
    • Identification and assessment of new vaccine candidates for group A streptococcal infections
    • McMillan D.J., Batzloff M.R., Browning C.L., Davies M.R., Good M.F., Sriprakash K.S., et al. Identification and assessment of new vaccine candidates for group A streptococcal infections. Vaccine 2004, 22(21-22):2783-2790.
    • (2004) Vaccine , vol.22 , Issue.21-22 , pp. 2783-2790
    • McMillan, D.J.1    Batzloff, M.R.2    Browning, C.L.3    Davies, M.R.4    Good, M.F.5    Sriprakash, K.S.6
  • 63
    • 1642498273 scopus 로고    scopus 로고
    • Identification of new candidate vaccine antigens made by Streptococcus pyogenes: purification and characterization of 16 putative extracellular lipoproteins
    • Lei B., Liu M., Chesney G.L., Musser J.M. Identification of new candidate vaccine antigens made by Streptococcus pyogenes: purification and characterization of 16 putative extracellular lipoproteins. J Infect Dis 2004, 189(1):79-89.
    • (2004) J Infect Dis , vol.189 , Issue.1 , pp. 79-89
    • Lei, B.1    Liu, M.2    Chesney, G.L.3    Musser, J.M.4
  • 64
    • 16244365147 scopus 로고    scopus 로고
    • Clinical and microbiological responses of volunteers to combined intranasal and oral inoculation with a Streptococcus gordonii carrier strain intended for future use as a group A streptococcus vaccine
    • Kotloff K.L., Wasserman S.S., Jones K.F., Livio S., Hruby D.E., Franke C.A., et al. Clinical and microbiological responses of volunteers to combined intranasal and oral inoculation with a Streptococcus gordonii carrier strain intended for future use as a group A streptococcus vaccine. Infect Immun 2005, 73(4):2360-2366.
    • (2005) Infect Immun , vol.73 , Issue.4 , pp. 2360-2366
    • Kotloff, K.L.1    Wasserman, S.S.2    Jones, K.F.3    Livio, S.4    Hruby, D.E.5    Franke, C.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.