Human leucocyte antigen-defined microchimerism early post-transplant does not predict for stable lung allograft function

Clinical and Experimental Immunology

Volumn 172, Issue 3, 2013, Pages 483-489

  Rowntree, L C ^a,b   Bayliss, J ^a,c   Nguyen, T H O ^a,b   Kotsimbos, T C ^a,b   Mifsud, N A ^a,b  

^a MONASH UNIVERSITY   (Australia)

^b ALFRED HOSPITAL   (Australia)

^c VICTORIAN INFECTIOUS DISEASES REFERENCE LABORATORY   (Australia)

Author keywords

HLA; Lung transplantation; Microchimerism

Indexed keywords

BASILIXIMAB; CALCINEURIN INHIBITOR; HLA B44 ANTIGEN;

ARTICLE; B LYMPHOCYTE; BRONCHOSCOPY; CLINICAL ARTICLE; FORCED EXPIRATORY VOLUME; GRAFT RECIPIENT; HLA SYSTEM; HUMAN; KIDNEY DYSFUNCTION; LUNG GRAFT REJECTION; LUNG TRANSPLANTATION; MICROCHIMERISM; PERIPHERAL BLOOD MONONUCLEAR CELL; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RISK ASSESSMENT; SPIROMETRY; TRANSBRONCHIAL BIOPSY;

ADULT; AGED; B-LYMPHOCYTE SUBSETS; BASE SEQUENCE; CHIMERISM; COHORT STUDIES; DNA PRIMERS; FEMALE; HLA-B44 ANTIGEN; HUMANS; KILLER CELLS, NATURAL; LUNG TRANSPLANTATION; MALE; MIDDLE AGED; MONOCYTES; RETROSPECTIVE STUDIES; T-LYMPHOCYTE SUBSETS; TISSUE DONORS; TRANSPLANTATION, HOMOLOGOUS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84876704527     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12075     Document Type: Article

References (27)

1. Sahota A, Gao S, Hayes J, Jindal RM. Microchimerism and rejection: a meta-analysis. Clin Transplant 2000; 14:345-350.
2. Hisanaga M, Hundrieser J, Böker K etal. Development, stability, and clinical correlations of allogeneic microchimerism after solid organ transplantation. Transplantation 1996; 61:40-45.
3. Hisanaga M, Schlitt HJ, Hundrieser J etal. Frequency and clinical correlations of allogeneic microchimerism after heart, liver, and lung transplantation. Transplant Proc 1997; 29:1215-1217.
4. Monaco AP. Chimerism in organ transplantation: conflicting experiments and clinical observations. Transplantation 2003; 75:13S-16.
5. Saraji A, Pourmand G, Mehrsai A etal. Microchimerism and renal transplantation: doubt still persists. Transplant Proc 2007; 39:948-950.
6. Starzl T, Demetris A, Murase N, Ildstad S, Ricordi C, Trucco M. Cell migration, chimerism, and graft acceptance. Lancet 1992; 339:1579-1582.
7. Starzl T. Cell migration and chimerism - a unifying concept in transplantation - with particular reference to HLA matching and tolerance induction. Transplant Proc 1993; 25:8-12.
8. Kawai T, Cosimi AB, Spitzer TR etal. HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med 2008; 358:353-361.
9. Scandling JD, Busque S, Dejbakhsh-Jones S etal. Tolerance and chimerism after renal and hematopoietic-cell transplantation. N Engl J Med 2008; 358:362-368.
10. Leventhal J, Abecassis M, Miller J etal. Chimerism and tolerance without GVHD or engraftment syndrome in HLA-mismatched combined kidney and hematopoietic stem cell transplantation. Sci Transl Med 2012; 4:124ra28.
11. Dave SD, Vanikar A, Trivedi HL etal. Stem cells versus donor specific transfusions for tolerance induction in living donor renal transplantation: a single-center experience. Transplantation 2013; 95:155-160.
12. Pilat N, Hock K, Wekerle T. Mixed chimerism through donor bone marrow transplnation: a tolerogenic cell therapy for application in organ transplantation. Curr Opin Organ Transplant 2012; 17:63-70.
13. Ildstad ST, Shirwan H, Leventhal J. Is durable macrochimerism key to achieving clinical transplantation tolerance? Curr Opin Organ Transplant 2011; 16:343-344.
14. Mathew JM, Leventhal JR, Miller J. Microchimerism in promoting graft acceptance in clinical transplantation. Curr Opin Organ Transplant 2011; 16:345-352.
15. McSherry C, Jackson A, Hertz MI, Bolman RM, Savik K, Reinsmoen NL. Sequential measurement of peripheral blood allogeneic microchimerism levels and association with pulmonary function. Transplantation 1996; 62:1811-1818.
16. Paantjens AWM, Van de Graaf EA, Heerkens HD etal. Chimerism of dendritic cell subsets in peripheral blood after lung transplantation. J Heart Lung Transplant 2011; 30:691-697.
17. Van der Meulen J, Mifsud NA, Abud D etal. Differential dynamics of donor DC and non-DC peripheral blood mononuclear cell microchimerism in lung transplantation. Clin Immunol 2009; 133:179-183.
18. Westall G, Kotsimbos T, Brooks A. CMV-specific CD8 T-cell dynamics in the blood and the lung allograft reflect viral reactivation following lung transplantation. Am J Transplant 2006; 6:577-584.
19. Yousem S, Berry G, Cagle P etal. Revision of the 1990 working formulation for the classification of pulmonary allograft rejection: Lung Rejection Study Group. J Heart Lung Transplant 1996; 15:1-15.
20. Estenne M, Maurer J, Boehler A etal. Bronchiolitis obliterans syndrome 2001: an update of the diagnostic criteria. J Heart Lung Transplant 2002; 21:297-310.
21. Estenne M, Hertz MI. Bronchiolitis obliterans after human lung transplantation. Am J Respir Crit Care Med 2002; 166:440-444.
22. Starzl TE. Chimerism and tolerance in transplantation. Proc Natl Acad Sci USA 2004; 101:14607-14614.
23. Sánchez-Fueyo A, Strom TB. Immunologic basis of graft rejection and tolerance following transplantation of liver or other solid organs. Gastroenterology 2011; 140:51-64.
24. Christie JD, Edwards LB, Kucheryavaya AY etal. The registry of the international society for heart and lung transplantation: twenty-eighth adult lung and heart-lung transplant report - 2011. J Heart Lung Transplant 2011; 30:1104-1122.
25. Benseler V, McCaughan G, Schlitt H, Bishop G, Bowen D, Bertolino P. The liver: a special case in transplantation tolerance. Semin Liver Dis 2007; 27:194-213.
26. Calhoun R, SivaSai KS, Sundaresan S etal. Development of bronchiolitis obliterans syndrome despite blood chimerism in human lung transplant recipients. Transpl Int 1999; 12:439-446.
27. Mori M, Beatty PG, Graves M, Boucher KM, Milford EL. HLA gene and haplotype frequencies in the North American population: the national marrow donor program donor registry. Transplantation 1997; 64:1017-1027.