The Influence of Estrogen Therapies on Bone Mineral Density in Premenopausal Women with Anorexia Nervosa and Amenorrhea

Vitamins and Hormones

Volumn 92, Issue , 2013, Pages 243-257

  Lebow, Jocelyn ^a   Sim, Leslie ^a  

^a MAYO CLINIC   (United States)

Author keywords

Anorexia nervosa; Bone mineral density; Hormone replacement; Oral contraceptive

Indexed keywords

EID: 84876700892     PISSN: 00836729     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-410473-0.00009-X     Document Type: Chapter

References (29)

1. Biller B., Saxe V., Herzog D., Rosenthal D., Holzman S., Klibanski A. Mechanisms of osteoporosis in adult and adolescent women with anorexia nervosa. The Journal of Clinical Endocrinology and Metabolism 1989, 68:548-554.
2. Eriksen E.F., Colvard D.S., Berg N.J., Graham M.L., Mann K.G., Spelsberg T.C., et al. Evidence of estrogen receptors in normal human osteoblast like cells. Science 1988, 241:84-86.
3. Gibson J.H., Mitchell A., Reeve J., Harries M.G. Treatment of reduced bone mineral density in athletic amenorrhea: A pilot study. Osteoporosis International 1999, 10:284-289.
4. Golden N.H., Lanzkowsky L., Schebendach J., Palestro C.J., Jacobson M.S., Shenker L.R. The effect of estrogen-progestin treatment on bone mineral density in anorexia nervosa. Journal of Pediatric and Adolescent Gynecology 2002, 15:135-143.
5. Gordon C.M., Grace E., Emans S., Feldman H., Goodman E., Becker K., et al. Effects of oral dehydroepiandrosterone on bone density in young women with anorexia nervosa: A randomized trial. The Journal of Clinical Endocrinology and Metabolism 2002, 87:4935-4941.
6. Grinspoon S., Thomas E., Miller K., Herzog D., Klibanski A. Effects of recombinant human IGF-I and oral contraceptive administration on bone density in anorexia nervosa. The Journal of Clinical Endocrinology and Metabolism 2002, 87:2883-2891.
7. Grinspoon S.K., Thomas E., Pitts S., Gross E., Mickley D., MIller K., et al. Prevalence and predictive factors for regional osteopenia in women with anorexia nervosa. Annals of Internal Medicine 2000, 133:790-794.
8. Guyatt G., Vist G., Falck-Ytter Y., Kunz R., Magrini N., Schunemann H. An emerging consensus on grading recommendations?. ACP Journal Club 2006, 144:A8-A9.
9. Haberland C.A., Seddick D., Marcus R., Bachrach L. A physician survey of therapy for exercise associated amenorrhea: A brief report. Clinical Journal of Sport Medicine 1995, 5:246-250.
10. Hergenroeder A.C., Smith E.O.B., Shypailo R., Jones L.A., Klish W.J., Ellis K. Bone mineral changes in young women with hypothalamic amenorrhea treated with oral contraceptives, medroxyprogesterone, or placebo over 12 months. American Journal of Obstetrics and Gynecology 1997, 176:1017-1025.
11. Herzog D.B., Keller M.B., Lavori P.W. Outcome in anorexia nervosa and bulimia nervosa: A review of the literature. The Journal of Nervous and Mental Disease 1988, 176:131-143.
12. Herzog W., MInne H., Deter C., Leidig G., Schellberg D., Wuster C., et al. Outcome of bone mineral density in anorexia nervosa patients 11.7 years after first admission. Journal of Bone and Mineral Research 1993, 8:597-605.
13. Klibanski A., Biller B.M.K., Schoenfeld D.A., Herzog D.B., Saxe V.C. The effects of estrogen administration on trabecular bone loss in young women with anorexia nervosa. The Journal of Clinical Endocrinology and Metabolism 1995, 80:898-904.
14. Misra M., Aggarwal A., Miller K., Almaxan C., Worley M., Soyka L., et al. Effects of anorexia nervosa on clinical, hematologic, biochemical, and bone density parameters in community-dwelling adolescent girls. Pediatrics 2004, 114:1574-1583.
15. Misra M., Klibanski A. The neuroendocrine basis of anorexia nervosa and its impact on bone metabolism. Neuroendocrinology 2011, 93:65-73.
16. Misra M., Miller K.K., Almazan C., Ramaswamy K., Lapcharoensap W., Worley M., et al. Alterations in cortisol secretory dynamics in adolescent girls with anorexia nervosa and effects on bone metabolism. The Journal of Clinical Endocrinology and Metabolism 2004, 89:4972-4980.
17. Misra M., Prabhakaran R., Miller K., Goldstein M., Mickley D., Clauss L., et al. Weight gain and restoration of menses as predictors of bone mineral density change in adolescent girls with anorexia nervosa-1. The Journal of Clinical Endocrinology and Metabolism 2008, 93:1231-1237.
18. Misra M., McGrane J., MIller K., Goldstein M., Ebrahimi S., Weigel T., et al. Effects of rhIGF-1 administration on surrogate markers of bone turnover in adolescents with anorexia nervosa. Bone 2009, 45:493-498.
19. Misra M., Katzman D., MIller K., Mendes N., Snelgrove D., Russell M., et al. Physiologic estrogen replacement increases bone density in adolescent girls with anorexia nervosa. Journal of Bone and Mineral Research 2011, 26:2430-2438.
20. Munoz-Calvo M.T., Barrios V., De Alvaro M.T.G., Lefort M., Mendez-Davila C., Argente J., et al. Maintained malnutrition produces a progressive decrease in (OPG)/RANKL ratio and leptin levels in patients with anorexia nervosa. Scandinavian Journal of Clinical and Laboratory Investigation 2007, 67:387-393.
21. Olmos J.M., Valero C., Gomez del Barrio A., Amado J., Hernandez J., Menendez-Arango J., et al. Time course of bone loss in patients with anorexia nervosa. The International Journal of Eating Disorders 2010, 43:537-542.
22. Register T.C., Jayo M.J., Jerome C.P. Oral contraceptive treatment inhibits the normal acquisition of bone mineral in skeletally immature young adult female monkeys. Osteoporosis International 1997, 7:348-353.
23. Rigotti N.A., Neer R.M., Skates S.J., Herzog D.B., Nussbaum S.R. The clinical course of osteoporosis in anorexia nervosa. Journal of the American Medical Association 1991, 265:1133-1138.
24. Rigotti N.A., Nussbaum S.R., Herzog D.B., Neer R.M. Osteoporosis in women with anorexia nervosa. The New England Journal of Medicine 1984, 311:1601-1606.
25. Strober M., Freeman R., Morrell W. The long-term course of severe anorexia nervosa in adolescents: Survival of recovery, relapse, and outcome predictors over 10-15 years in a prospective study. The International Journal of Eating Disorders 1997, 22:339-360.
26. Strokosch G.R., Friedman A.J., Wu S.C., Kamin M. Effects of an oral contraceptive (norgestimate/ethinyl estradiol) on bone mineral density in adolescent females with anorexia nervosa: A double-blind, placebo-controlled study. The Journal of Adolescent Health 2006, 39:819-827.
27. Ward A., Brown J., Treasure J. Persistent osteopenia after recovery from anorexia nervosa. The International Journal of Eating Disorders 1997, 22:71-75.
28. Warren M.P., Miller K.K., Olson W.H., Grinspoon S.K., Friedman A.J. Effects of an oral contraceptive (norgestimate/ethinyl estradiol) on bone mineral density in women with hypothalamic amenorrhea and osteopenia: An open-label extension of a double-blind, placebo-controlled study. Contraception 2005, 72:206-211.
29. Weissberger A.J., Ho K.K., Lazarus L. Contrasting effects of oral and transdermal routes of estrogen replacement therapy on 24-hour growth hormone (GH) secretion, insulin-like growth factor 1, and GH-binding protein in postmenopausal women. The Journal of Clinical Endocrinology and Metabolism 1991, 72:374-381.