A randomised phase III intergroup trial comparing high-dose infusional 5-fluorouracil with or without folinic acid with standard bolus 5-fluorouracil/folinic acid in the adjuvant treatment of stage III colon cancer: The Pan-European Trial in Adjuvant Colon Cancer 2 study

European Journal of Cancer

Volumn 49, Issue 8, 2013, Pages 1868-1875

  Köhne, Claus Henning ^a   Bedenne, Laurent ^b   Carrato, Alfredo ^c   Bouché, Olivier ^d   Popov, Ivan ^e   Gaspà, Losa ^f   Valladares, Manuel ^g   Rougier, Phillipe ^h   Gog, Christiane ⁱ   Reichardt, Peter ^j   Wils, Jacques ^k   Pignatti, Francesco ^l   Biertz, Frank ^m  

^a UNIVERSITY OF OLDENBURG   (Germany)

^b DIJON UNIVERSITY HOSPITAL   (France)

^c HOSPITAL GENERAL UNIVERSITARIO DE ELCHE   (Spain)

^d SERVICE DE DERMATOLOGIE   (France)

^e INSTITUTE FOR ONCOLOGY AND RADIOLOGY OF SERBIA   (Serbia)

^f Servicio de Oncología Médica   (Spain)

^g HOSPITAL JUAN CANALEJO   (Spain)

^h HÔPITAL AMBROISE PARÉ   (France)

ⁱ UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^j HELIOS Klinikum Bad Saarow   (Germany)

^k LAURENTIUS HOSPITAL   (Netherlands)

^l EUROPEAN MEDICINES AGENCY   (United Kingdom)

^m HANNOVER MEDICAL SCHOOL   (Germany)

more..

Author keywords

5 Flurouracil; Adjuvant treatment; Bolus; Colon cancer; High dose; Infusional

Indexed keywords

FLUOROURACIL; FOLINIC ACID;

ADULT; AGED; ARTICLE; CANCER ADJUVANT THERAPY; CANCER GRADING; CANCER STAGING; CANCER SURVIVAL; COLON ADENOCARCINOMA; CONTROLLED STUDY; DIARRHEA; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MEGADOSE; DRUG TOLERABILITY; FEMALE; FOLLOW UP; HUMAN; LEUKOPENIA; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MULTIPLE CYCLE TREATMENT; OVERALL SURVIVAL; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RECURRENCE FREE SURVIVAL;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHEMOTHERAPY, ADJUVANT; COLONIC NEOPLASMS; DIARRHEA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; EUROPE; FEMALE; FLUOROURACIL; HUMANS; INFUSIONS, INTRAVENOUS; KAPLAN-MEIER ESTIMATE; LEUCOVORIN; LEUKOPENIA; MALE; MIDDLE AGED; NEOPLASM STAGING; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84876695158     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2013.01.030     Document Type: Article

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