-
3
-
-
0033969685
-
Antidepressant effects of ketamine in depressed patients
-
Berman RM, Cappiello A, Anand A, et al. Antidepressant effects of ketamine in depressed patients. Biol Psych. 2000 ; 47: 351-354
-
(2000)
Biol Psych
, vol.47
, pp. 351-354
-
-
Berman, R.M.1
Cappiello, A.2
Anand, A.3
-
4
-
-
0003390338
-
The natural history of the house mouse
-
Berry RJ. The natural history of the house mouse. Field Studies. 1970 ; 3: 219-226
-
(1970)
Field Studies
, vol.3
, pp. 219-226
-
-
Berry, R.J.1
-
5
-
-
0017046993
-
Prediction of tricyclic antidepressant response: A critical review
-
Bielski RJ, Friedel RO. Prediction of tricyclic antidepressant response: A critical review. Arch Gen Psychiatry. 1976 ; 33: 1479-1489
-
(1976)
Arch Gen Psychiatry
, vol.33
, pp. 1479-1489
-
-
Bielski, R.J.1
Friedel, R.O.2
-
6
-
-
0000466516
-
-
Sadock BJ Sadock VA, ed. New York: Lippincott, Williams and Wilkins;
-
Blazer DG Comprehensive Textbook of Psychiatry. Sadock BJ Sadock VA, ed. New York: Lippincott, Williams and Wilkins ; 2000: 1298-1308.
-
(2000)
Comprehensive Textbook of Psychiatry
, pp. 1298-1308
-
-
Blazer, D.G.1
-
7
-
-
77954686636
-
The well of novel antidepressants: Running dry
-
Blier P. The well of novel antidepressants: Running dry. J Psychiatry Neurosci. 2010 ; 35: 219-220
-
(2010)
J Psychiatry Neurosci
, vol.35
, pp. 219-220
-
-
Blier, P.1
-
8
-
-
84875236117
-
Models for depression in drug screening and preclinical studies: Future directions
-
Borsini F. Models for depression in drug screening and preclinical studies: Future directions. World J Pharmacol. 2012 ; 1: 21-29
-
(2012)
World J Pharmacol
, vol.1
, pp. 21-29
-
-
Borsini, F.1
-
9
-
-
0015103116
-
The physiology of population limitation in rodents - A review
-
Brain PF. The physiology of population limitation in rodents - a review. Commun Behav Biol. 1971 ; 6: 115-123
-
(1971)
Commun Behav Biol
, vol.6
, pp. 115-123
-
-
Brain, P.F.1
-
11
-
-
0036238750
-
Epidemiology of depression throughout the female life cycle
-
Burt VK, Stein K. Epidemiology of depression throughout the female life cycle. J Clin Psychiatry. 2002 ; 63: 9-15
-
(2002)
J Clin Psychiatry
, vol.63
, pp. 9-15
-
-
Burt, V.K.1
Stein, K.2
-
12
-
-
79959542106
-
Rodent models of depression: Forced swim and tail suspension behavioural despair tests in rats and mice
-
Castagné V, Moser P, Roux S, et al. Rodent models of depression: Forced swim and tail suspension behavioural despair tests in rats and mice. Curr Protoc Pharmacol. 2011 ;:
-
(2011)
Curr Protoc Pharmacol
-
-
Castagné, V.1
Moser, P.2
Roux, S.3
-
13
-
-
84859964337
-
Accumulation of an antidepressant in vesiculogenic membranes of yeast cells triggers autophagy
-
Chen J, Korostyshevsky D, Lee S, et al. Accumulation of an antidepressant in vesiculogenic membranes of yeast cells triggers autophagy. PLoS ONE. 2012 ; 7: e34024
-
(2012)
PLoS ONE
, vol.7
, pp. 34024
-
-
Chen, J.1
Korostyshevsky, D.2
Lee, S.3
-
14
-
-
0023000624
-
Adaptation of the tail suspension test to the rat
-
Chermat R, Thierry B, Mico JA, et al. Adaptation of the tail suspension test to the rat. J Pharmacol. 1986 ; 17: 348-350
-
(1986)
J Pharmacol
, vol.17
, pp. 348-350
-
-
Chermat, R.1
Thierry, B.2
Mico, J.A.3
-
15
-
-
0042145925
-
Modifications of pharmacology of reserpine and serotonin by iproniazid
-
Chessin M, Dubnick B, Kramer ER, et al. Modifications of pharmacology of reserpine and serotonin by iproniazid. Federation Proc. 1956 ; 15: 409
-
(1956)
Federation Proc
, vol.15
, pp. 409
-
-
Chessin, M.1
Dubnick, B.2
Kramer, E.R.3
-
16
-
-
60849086169
-
Comparative efficacy and acceptability of 12 new-generation antidepressants: A multiple-treatments meta-analysis
-
Cipriani A, Furukawa TA, Salanti G, et al. Comparative efficacy and acceptability of 12 new-generation antidepressants: A multiple-treatments meta-analysis. Lancet. 2009 ; 373: 746-758
-
(2009)
Lancet
, vol.373
, pp. 746-758
-
-
Cipriani, A.1
Furukawa, T.A.2
Salanti, G.3
-
17
-
-
0027139227
-
An ethological analysis of the effects of chlordiazepoxide and bretazenil (Ro16-6028) in the murine elevated plus-maze
-
Cole JC, Rodgers RJ. An ethological analysis of the effects of chlordiazepoxide and bretazenil (Ro16-6028) in the murine elevated plus-maze. Behav Pharmacol. 1993 ; 4: 573-580
-
(1993)
Behav Pharmacol
, vol.4
, pp. 573-580
-
-
Cole, J.C.1
Rodgers, R.J.2
-
18
-
-
81855173446
-
Predictors of long-term prognosis of depression
-
Colman I, Naicker K, Zeng Y, et al. Predictors of long-term prognosis of depression.. CMAJ. 2011 ; 183: 1969-1976
-
(2011)
CMAJ
, vol.183
, pp. 1969-1976
-
-
Colman, I.1
Naicker, K.2
Zeng, Y.3
-
19
-
-
26044460006
-
The ascent of mouse: Advances in modelling human depression and anxiety
-
Cryan JF, Holmes A. The ascent of mouse: Advances in modelling human depression and anxiety. Nat Rev Drug Discov. 2005 ; 4: 785-790
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 785-790
-
-
Cryan, J.F.1
Holmes, A.2
-
20
-
-
2042546746
-
In search of a depressed mouse: Utility of models for studying depression-related behavior in genetically modified mice
-
Cryan JF, Mombereau C. In search of a depressed mouse: Utility of models for studying depression-related behavior in genetically modified mice. Mol Psychiatry. 2004 ; 9: 326-3577
-
(2004)
Mol Psychiatry
, vol.9
, pp. 326-3577
-
-
Cryan, J.F.1
Mombereau, C.2
-
21
-
-
0036570222
-
Assessing antidepressant activity in rodents: Recent developments and future needs
-
Cryan JF, Markou A, Lucki I. Assessing antidepressant activity in rodents: Recent developments and future needs. Trends Pharmacol Sci. 2002 ; 23: 238-245
-
(2002)
Trends Pharmacol Sci
, vol.23
, pp. 238-245
-
-
Cryan, J.F.1
Markou, A.2
Lucki, I.3
-
22
-
-
19944380200
-
The tail suspension test as a model for assessing antidepressant activity: Review of pharmacological and genetic studies in mice
-
Cryan JF, Mombereau C, Vassout A. The tail suspension test as a model for assessing antidepressant activity: Review of pharmacological and genetic studies in mice. Neurosci Biobehav Rev. 2005 ; 29: 571-625
-
(2005)
Neurosci Biobehav Rev
, vol.29
, pp. 571-625
-
-
Cryan, J.F.1
Mombereau, C.2
Vassout, A.3
-
23
-
-
0029081299
-
Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants
-
Detke MJ, Rickels M, Lucki I. Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants. Psychopharmacology. 1995 ; 121: 66-72
-
(1995)
Psychopharmacology
, vol.121
, pp. 66-72
-
-
Detke, M.J.1
Rickels, M.2
Lucki, I.3
-
26
-
-
0022437594
-
Ethological aspects of psychiatry
-
Dixon AK. Ethological aspects of psychiatry. Schweiz Arch Neurol Psychiatr. 1986 ; 137: 151-163
-
(1986)
Schweiz Arch Neurol Psychiatr
, vol.137
, pp. 151-163
-
-
Dixon, A.K.1
-
27
-
-
0024573990
-
Ethological studies in animals and man: Their use in psychiatry
-
Dixon AK, Fisch HU, Huber C, et al. Ethological studies in animals and man: Their use in psychiatry. Pharmacopsychiatry. 1989 ; 22: 44-50
-
(1989)
Pharmacopsychiatry
, vol.22
, pp. 44-50
-
-
Dixon, A.K.1
Fisch, H.U.2
Huber, C.3
-
28
-
-
0032864985
-
History of modern psychopharmacology - A personal view with an emphasis on antidepressants
-
Domino EF. History of modern psychopharmacology - a personal view with an emphasis on antidepressants. Psychosom Med. 1999 ; 61: 591-598
-
(1999)
Psychosom Med
, vol.61
, pp. 591-598
-
-
Domino, E.F.1
-
29
-
-
0036769874
-
The pharmacologic management of SSRI-induced side effects: A survey of psychiatrists
-
Dording CM, Mischoulon D, Petersen TJ, et al. The pharmacologic management of SSRI-induced side effects: A survey of psychiatrists. Ann Clin Psychiatry. 2002 ; 14: 143-147
-
(2002)
Ann Clin Psychiatry
, vol.14
, pp. 143-147
-
-
Dording, C.M.1
Mischoulon, D.2
Petersen, T.J.3
-
30
-
-
77955863459
-
Models of depression
-
Duman CH. Models of depression. Vitam Horm. 2010 ; 82: 1-21
-
(2010)
Vitam Horm
, vol.82
, pp. 1-21
-
-
Duman, C.H.1
-
32
-
-
0029967073
-
Definition and epidemiology of treatment-resistant depression
-
Fava M, Davidson KG. Definition and epidemiology of treatment-resistant depression. Psychiatr Clin North Am. 1996 ; 19: 179-200
-
(1996)
Psychiatr Clin North Am
, vol.19
, pp. 179-200
-
-
Fava, M.1
Davidson, K.G.2
-
33
-
-
0030561375
-
Chronic mild stress and sucrose consumption: Validity as a model of depression
-
Forbes NF, Stewart CA, Matthews K, et al. Chronic mild stress and sucrose consumption: Validity as a model of depression. Physiol Behav. 1996 ; 60: 1481-1484
-
(1996)
Physiol Behav
, vol.60
, pp. 1481-1484
-
-
Forbes, N.F.1
Stewart, C.A.2
Matthews, K.3
-
34
-
-
73449112663
-
Antidepressant drug effects and depression severity: A patient-level meta-analysis
-
Fournier JC, DeRubeis RJ, Hollon SD, et al. Antidepressant drug effects and depression severity: A patient-level meta-analysis. JAMA. 2010 ; 303: 47-53
-
(2010)
JAMA
, vol.303
, pp. 47-53
-
-
Fournier, J.C.1
Derubeis, R.J.2
Hollon, S.D.3
-
35
-
-
84878437204
-
Self-medication among traumatized youth: Structural equation modeling of pathways between trauma history, substance misuse, and psychological distress
-
2012
-
Garland E, Pettus-Davis C, Howard M. Self-medication among traumatized youth: Structural equation modeling of pathways between trauma history, substance misuse, and psychological distress. J Behav Med. 2012 2012 ;:
-
(2012)
J Behav Med
-
-
Garland, E.1
Pettus-Davis, C.2
Howard, M.3
-
36
-
-
0037460745
-
Relapse prevention with antidepressant drug treatment in depressive disorders: A systematic review
-
Geddes J, Carney SM, Davies C, et al. Relapse prevention with antidepressant drug treatment in depressive disorders: A systematic review. Lancet. 2003 ; 361: 653-661
-
(2003)
Lancet
, vol.361
, pp. 653-661
-
-
Geddes, J.1
Carney, S.M.2
Davies, C.3
-
38
-
-
33748922166
-
FDA's regulations under the Kefauver-Harris Drug Amendments of 1962
-
Goodrich WW. FDA's regulations under the Kefauver-Harris Drug Amendments of 1962. Food Drug Cosmet Law J. 1963 ; 18: 561-569
-
(1963)
Food Drug Cosmet Law J
, vol.18
, pp. 561-569
-
-
Goodrich, W.W.1
-
39
-
-
85014985636
-
A comparison of the social postures of some common laboratory rodents
-
Grant EC, MacKintosh JH. A comparison of the social postures of some common laboratory rodents. Behaviour. 1963 ; 21: 246-259
-
(1963)
Behaviour
, vol.21
, pp. 246-259
-
-
Grant, E.C.1
MacKintosh, J.H.2
-
42
-
-
59249086197
-
Depression as an evolutionary adaptation: Implications for the development of preclinical models
-
Hendrie CA, Pickles AR. Depression as an evolutionary adaptation: Implications for the development of preclinical models. Med Hypotheses. 2009 ; 72: 342-347
-
(2009)
Med Hypotheses
, vol.72
, pp. 342-347
-
-
Hendrie, C.A.1
Pickles, A.R.2
-
43
-
-
77649338497
-
Depression as an evolutionary adaptation: Anatomical organisation around the third ventricle
-
Hendrie CA, Pickles AR. Depression as an evolutionary adaptation: Anatomical organisation around the third ventricle. Med Hypotheses. 2010 ; 74: 735-740
-
(2010)
Med Hypotheses
, vol.74
, pp. 735-740
-
-
Hendrie, C.A.1
Pickles, A.R.2
-
44
-
-
0032029959
-
Pairbond disruption in Mongolian gerbils: Effects on subsequent social behaviour
-
Hendrie CA, Starkey NJ. Pairbond disruption in Mongolian gerbils: Effects on subsequent social behaviour. Physiol Behav. 1998 ; 63: 895-901
-
(1998)
Physiol Behav
, vol.63
, pp. 895-901
-
-
Hendrie, C.A.1
Starkey, N.J.2
-
45
-
-
84891483535
-
Behavioural scientists appear not to have specialist knowledge of laboratory animal behaviour
-
Hendrie CA, Phillips D, Pickles AR. Behavioural scientists appear not to have specialist knowledge of laboratory animal behaviour. J Psychopharm. 2011 ; 25: A35 - A35
-
(2011)
J Psychopharm
, vol.25
-
-
Hendrie, C.A.1
Phillips, D.2
Pickles, A.R.3
-
46
-
-
77649339834
-
Evidence to suggest that self-medication with alcohol is not an effective treatment for the control of depression
-
Hendrie CA, Sarailly J, Starkey NJ. Evidence to suggest that self-medication with alcohol is not an effective treatment for the control of depression. J Psychopharm. 1998 ; 12: 112
-
(1998)
J Psychopharm
, vol.12
, pp. 112
-
-
Hendrie, C.A.1
Sarailly, J.2
Starkey, N.J.3
-
47
-
-
0029947623
-
Exploration and predation models of anxiety: Evidence from laboratory and wild species
-
Hendrie CA, Weiss SM, Eilam D. Exploration and predation models of anxiety: Evidence from laboratory and wild species. Pharmacol Biochem Behav. 1996 ; 54: 13-20
-
(1996)
Pharmacol Biochem Behav
, vol.54
, pp. 13-20
-
-
Hendrie, C.A.1
Weiss, S.M.2
Eilam, D.3
-
48
-
-
27644460326
-
The drug discovery process
-
Herrling PL. The drug discovery process. Prog Drug Res. 2005 ; 62: 1-14
-
(2005)
Prog Drug Res
, vol.62
, pp. 1-14
-
-
Herrling, P.L.1
-
49
-
-
0035013631
-
Expanding the horizons of depression: Expanding the monoamine hypothesis
-
Hindmarch I. Expanding the horizons of depression: Expanding the monoamine hypothesis. Hum Psychopharm Clin Exp. 2001 ; 16: 203-218
-
(2001)
Hum Psychopharm Clin Exp
, vol.16
, pp. 203-218
-
-
Hindmarch, I.1
-
51
-
-
0034475077
-
Behavioral profile of wild mice in the elevated plus-maze test for anxiety
-
Holmes A, Parmigiani S, Ferrari PF, et al. Behavioral profile of wild mice in the elevated plus-maze test for anxiety. Physiol Behav. 2000 ; 71: 509-516
-
(2000)
Physiol Behav
, vol.71
, pp. 509-516
-
-
Holmes, A.1
Parmigiani, S.2
Ferrari, P.F.3
-
52
-
-
69949180430
-
A systematic review of long-term studies of drug treated and non-drug treated depression
-
Hughes S, Cohen D. A systematic review of long-term studies of drug treated and non-drug treated depression. J Affect Disord. 2009 ; 118: 9-18
-
(2009)
J Affect Disord
, vol.118
, pp. 9-18
-
-
Hughes, S.1
Cohen, D.2
-
53
-
-
3142735110
-
Antidepressants and the risk of suicidal behaviours
-
Jick H, Kaye JA, Jick SS. Antidepressants and the risk of suicidal behaviours. JAMA. 2004 ; 292: 338-343
-
(2004)
JAMA
, vol.292
, pp. 338-343
-
-
Jick, H.1
Kaye, J.A.2
Jick, S.S.3
-
54
-
-
0033372057
-
Behavioural consequences of repeated social defeat in the mouse: Preliminary evaluation of a potential animal model of depression
-
Keeney AJ, Hogg S. Behavioural consequences of repeated social defeat in the mouse: Preliminary evaluation of a potential animal model of depression. Behav Pharmacol. 1999 ; 10: 753-764
-
(1999)
Behav Pharmacol
, vol.10
, pp. 753-764
-
-
Keeney, A.J.1
Hogg, S.2
-
55
-
-
0030770172
-
The olfactory bulbectomized rat as a model of depression: An update
-
Kelly P, Wrynn AS, Leonard BE. The olfactory bulbectomized rat as a model of depression: An update. Pharmacol Ther. 1997 ; 74: 299-316
-
(1997)
Pharmacol Ther
, vol.74
, pp. 299-316
-
-
Kelly, P.1
Wrynn, A.S.2
Leonard, B.E.3
-
56
-
-
54049133277
-
The molecular neurobiology of depression
-
Krishnan V, Nestler EJ. The molecular neurobiology of depression. Nature. 2008 ; 455: 894-902
-
(2008)
Nature
, vol.455
, pp. 894-902
-
-
Krishnan, V.1
Nestler, E.J.2
-
57
-
-
79958088436
-
Animal models of depression: Molecular perspectives
-
Krishnan V, Nestler EJ. Animal models of depression: molecular perspectives. Curr Topics Behav Neurosci. 2011 ; 7: 121-147
-
(2011)
Curr Topics Behav Neurosci
, vol.7
, pp. 121-147
-
-
Krishnan, V.1
Nestler, E.J.2
-
59
-
-
29644436010
-
Serotonin and depression: A disconnect between the advertisements and the scientific literature
-
Lacasse JR, Leo J. Serotonin and depression: A disconnect between the advertisements and the scientific literature. PLoS Med. 2005 ; 2 (12). e392
-
(2005)
PLoS Med
, vol.2
, Issue.12
, pp. 392
-
-
Lacasse, J.R.1
Leo, J.2
-
60
-
-
45549086754
-
The media and the chemical imbalance theory of depression
-
Leo J, Lacasse JR. The media and the chemical imbalance theory of depression. Society. 2008 ; 45: 35-45
-
(2008)
Society
, vol.45
, pp. 35-45
-
-
Leo, J.1
Lacasse, J.R.2
-
61
-
-
84860393629
-
Antidepressant utilization, adherence, and health care spending in the United States: The case of MDD patients 2000-2007
-
Lin H-C, Erickson SR, Balkrishnan R. Antidepressant utilization, adherence, and health care spending in the United States: The case of MDD patients 2000-2007. Health Outcomes Res Med. 2011 ; 2: e79 - e89
-
(2011)
Health Outcomes Res Med
, vol.2
-
-
Lin, H.-C.1
Erickson, S.R.2
Balkrishnan, R.3
-
62
-
-
0035462130
-
From idea to market: The drug approval process
-
Lipsky MS, Sharp LK. From idea to market: The drug approval process. J Am Board Fam Pract. 2001 ; 14: 362-367
-
(2001)
J Am Board Fam Pract
, vol.14
, pp. 362-367
-
-
Lipsky, M.S.1
Sharp, L.K.2
-
64
-
-
33748171121
-
Animal models of depression in drug discovery: A historical perspective
-
McArthur R, Borsini F. Animal models of depression in drug discovery: A historical perspective. Pharm Biochem Behav. 2006 ; 84: 436-452
-
(2006)
Pharm Biochem Behav
, vol.84
, pp. 436-452
-
-
McArthur, R.1
Borsini, F.2
-
66
-
-
13444259349
-
NICE guidelines for the management of depression are clear for severe depression, but uncertain for mild or moderate depression
-
Middleton H, Shaw I, Feder G. NICE guidelines for the management of depression are clear for severe depression, but uncertain for mild or moderate depression. BMJ. 2005 ; 330: 267-268
-
(2005)
BMJ
, vol.330
, pp. 267-268
-
-
Middleton, H.1
Shaw, I.2
Feder, G.3
-
67
-
-
77955114844
-
Is pharma running out of brainy ideas?
-
Miller G. Is pharma running out of brainy ideas?. Science. 2010 ; 329: 502-504
-
(2010)
Science
, vol.329
, pp. 502-504
-
-
Miller, G.1
-
68
-
-
81455159103
-
Proportion of antidepressants prescribed without a psychiatric diagnosis is growing
-
Mojtabai R, Olfson M. Proportion of antidepressants prescribed without a psychiatric diagnosis is growing. Health Aff (Millwood). 2011 ; 30: 1434-1442
-
(2011)
Health Aff (Millwood)
, vol.30
, pp. 1434-1442
-
-
Mojtabai, R.1
Olfson, M.2
-
69
-
-
0029804472
-
Drug treatment of depression in the 1990s. An overview of achievements and future possibilities
-
Möller HJ, Volz HP. Drug treatment of depression in the 1990s. An overview of achievements and future possibilities. Drugs. 1996 ; 52: 625-638
-
(1996)
Drugs
, vol.52
, pp. 625-638
-
-
Möller, H.J.1
Volz, H.P.2
-
70
-
-
34248151827
-
Are antidepressants as effective as claimed? No, they are not effective at all
-
Moncrieff J. Are antidepressants as effective as claimed? No, they are not effective at all. Can J Psychiatry. 2007 ; 52: 96-97
-
(2007)
Can J Psychiatry
, vol.52
, pp. 96-97
-
-
Moncrieff, J.1
-
71
-
-
0028914984
-
Attenuation of sucrose consumption in mice by chronic mild stress and its restoration by imipramine
-
Monleon S, D'Aquila P, Parra A, et al. Attenuation of sucrose consumption in mice by chronic mild stress and its restoration by imipramine. Psychopharmacology. 1995 ; 117: 453-457
-
(1995)
Psychopharmacology
, vol.117
, pp. 453-457
-
-
Monleon, S.1
D'Aquila, P.2
Parra, A.3
-
73
-
-
77957273984
-
Animal models of neuropsychiatric disorders
-
Nestler EJ, Hyman SE. Animal models of neuropsychiatric disorders. Nat Neurosci. 2010 ; 13: 1161-1169
-
(2010)
Nat Neurosci
, vol.13
, pp. 1161-1169
-
-
Nestler, E.J.1
Hyman, S.E.2
-
75
-
-
79959197550
-
ECNP Summit on the future of CNS drug research in Europe 2011: Report prepared for ECNP by David Nutt and Guy Goodwin
-
Nutt D, Goodwin G. ECNP Summit on the future of CNS drug research in Europe 2011: Report prepared for ECNP by David Nutt and Guy Goodwin. Eur Neuropsychopharmacol. 2011 ; 21: 495-499
-
(2011)
Eur Neuropsychopharmacol
, vol.21
, pp. 495-499
-
-
Nutt, D.1
Goodwin, G.2
-
76
-
-
57049188862
-
Does the probability of receiving placebo influence clinical trial outcome? A meta-regression of double-blind, randomized clinical trials in MDD
-
Papakostas GI, Fava M. Does the probability of receiving placebo influence clinical trial outcome? A meta-regression of double-blind, randomized clinical trials in MDD. Eur Neuropsychopharm. 2009 ; 19: 34-40
-
(2009)
Eur Neuropsychopharm
, vol.19
, pp. 34-40
-
-
Papakostas, G.I.1
Fava, M.2
-
77
-
-
77649234756
-
How to improve R&D productivity: The pharmaceutical industry's grand challenge
-
Paul SM, Mytelka DS, Dunwiddie CT, et al. How to improve R&D productivity: The pharmaceutical industry's grand challenge. Nature Rev Drug Discov. 2010 ; 9: 203-214
-
(2010)
Nature Rev Drug Discov
, vol.9
, pp. 203-214
-
-
Paul, S.M.1
Mytelka, D.S.2
Dunwiddie, C.T.3
-
78
-
-
84863421486
-
Short-term individual housing induced social deficits in female Mongolian gerbils: Attenuation by chronic but not acute imipramine
-
Pickles AR, Hagan JJ, Jones DNC, et al. Short-term individual housing induced social deficits in female Mongolian gerbils: Attenuation by chronic but not acute imipramine. Neuropharmacology. 2012 ; 62: 1993-1998
-
(2012)
Neuropharmacology
, vol.62
, pp. 1993-1998
-
-
Pickles, A.R.1
Hagan, J.J.2
Jones, D.N.C.3
-
79
-
-
77954275627
-
Efficacy and effectiveness of antidepressants: Current status of research
-
Pigott HE, Leventhal AM, Alter GS, et al. Efficacy and effectiveness of antidepressants: Current status of research. Psychother Psychosom. 2010 ; 79: 267-279
-
(2010)
Psychother Psychosom
, vol.79
, pp. 267-279
-
-
Pigott, H.E.1
Leventhal, A.M.2
Alter, G.S.3
-
81
-
-
0017618768
-
Depression: A new animal model sensitive to antidepressant treatments
-
Porsolt R, Le Pichon M, Jalfre M. Depression: A new animal model sensitive to antidepressant treatments. Nature. 1977 ; 266: 730-732
-
(1977)
Nature
, vol.266
, pp. 730-732
-
-
Porsolt, R.1
Le Pichon, M.2
Jalfre, M.3
-
82
-
-
0020317620
-
Agonistic behaviour in rats: Evidence for non-involvement of opioid mechanisms
-
Rodgers RJ, Hendrie CA. Agonistic behaviour in rats: Evidence for non-involvement of opioid mechanisms. Physiol Behav. 1982 ; 29: 85-90
-
(1982)
Physiol Behav
, vol.29
, pp. 85-90
-
-
Rodgers, R.J.1
Hendrie, C.A.2
-
83
-
-
0020521578
-
Social conflict activates status-dependent endogenous analgesic or hyperalgesic mechanisms in male mice: Effects of naloxone on nociception and behaviour
-
Rodgers RJ, Hendrie CA. Social conflict activates status-dependent endogenous analgesic or hyperalgesic mechanisms in male mice: Effects of naloxone on nociception and behaviour. Physiol Behav. 1983 ; 30: 775-780
-
(1983)
Physiol Behav
, vol.30
, pp. 775-780
-
-
Rodgers, R.J.1
Hendrie, C.A.2
-
84
-
-
0020576329
-
Naloxone partially antagonizes post-encounter analgesia and enhances defensive responding in male rats exposed to attack from lactating conspecifics
-
Rodgers RJ, Hendrie CA, Waters AJ. Naloxone partially antagonizes post-encounter analgesia and enhances defensive responding in male rats exposed to attack from lactating conspecifics. Physiol Behav. 1983 ; 30: 781-786
-
(1983)
Physiol Behav
, vol.30
, pp. 781-786
-
-
Rodgers, R.J.1
Hendrie, C.A.2
Waters, A.J.3
-
85
-
-
19544368850
-
Anhedonia and motivational deficits in rats: Impact of chronic social stress
-
Rygula R, Abumaria N, Flugge G, et al. Anhedonia and motivational deficits in rats: Impact of chronic social stress. Behav Brain Res. 2005 ; 162: 127-134
-
(2005)
Behav Brain Res
, vol.162
, pp. 127-134
-
-
Rygula, R.1
Abumaria, N.2
Flugge, G.3
-
88
-
-
0032983086
-
Antidepressants for the new millennium
-
Skolnick P. Antidepressants for the new millennium. Eur J Pharmacol. 1999 ; 375: 31-40
-
(1999)
Eur J Pharmacol
, vol.375
, pp. 31-40
-
-
Skolnick, P.1
-
90
-
-
19944391381
-
The olfactory bulbectomised rat as a model of depression
-
Song C, Leonard BE. The olfactory bulbectomised rat as a model of depression. Neurosci Biobehav Rev. 2005 ; 29: 627-647
-
(2005)
Neurosci Biobehav Rev
, vol.29
, pp. 627-647
-
-
Song, C.1
Leonard, B.E.2
-
91
-
-
0021990491
-
The tail suspension test: A new method for screening antidepressants in mice
-
Steru L, Chermat R, Thierry B, et al. The tail suspension test: A new method for screening antidepressants in mice. Psychopharmacology (Berl). 1985 ; 85: 367-370
-
(1985)
Psychopharmacology (Berl)
, vol.85
, pp. 367-370
-
-
Steru, L.1
Chermat, R.2
Thierry, B.3
-
93
-
-
30044433660
-
Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: Implications for clinical practice
-
Trivedi MH, Rush AJ, Wisniewski SR, et al. Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: Implications for clinical practice. Am J Psychiatry. 2006 ; 163: 28-40
-
(2006)
Am J Psychiatry
, vol.163
, pp. 28-40
-
-
Trivedi, M.H.1
Rush, A.J.2
Wisniewski, S.R.3
-
94
-
-
0032738216
-
Ethological research in clinical psychiatry: The study of nonverbal behavior during interviews
-
Troisi A. Ethological research in clinical psychiatry: The study of nonverbal behavior during interviews. Neurosci Biobehav Rev. 1999 ; 23: 905-913
-
(1999)
Neurosci Biobehav Rev
, vol.23
, pp. 905-913
-
-
Troisi, A.1
-
95
-
-
0025000814
-
Ethological assessment of the DSM-III subtyping of unipolar depression
-
Troisi A, Pasini A, Bersani G, et al. Ethological assessment of the DSM-III subtyping of unipolar depression. Acta Psychiatr Scand. 1990 ; 81: 560-564
-
(1990)
Acta Psychiatr Scand
, vol.81
, pp. 560-564
-
-
Troisi, A.1
Pasini, A.2
Bersani, G.3
-
96
-
-
38349049478
-
Selective publication of antidepressant trials and its influence on apparent effcacy
-
Turner EH, Matthews AM, Linardatos E, et al. Selective publication of antidepressant trials and its influence on apparent effcacy. N Engl J Med. 2008 ; 358: 252-256
-
(2008)
N Engl J Med
, vol.358
, pp. 252-256
-
-
Turner, E.H.1
Matthews, A.M.2
Linardatos, E.3
-
97
-
-
2442569082
-
Global burden of depressive disorders in the year 2000
-
Üstün TB, Ayuso-Mateos JL, Chatterji S, et al. Global burden of depressive disorders in the year 2000. Br J Psychiatry. 2004 ; 184: 386-392
-
(2004)
Br J Psychiatry
, vol.184
, pp. 386-392
-
-
Üstün, T.B.1
Ayuso-Mateos, J.L.2
Chatterji, S.3
-
98
-
-
79952368700
-
Biological psychiatry: Still marching forward in a dead end
-
Van Praag HM. Biological psychiatry: Still marching forward in a dead end. World Psychiatry. 2010 ; 9: 164-165
-
(2010)
World Psychiatry
, vol.9
, pp. 164-165
-
-
Van Praag, H.M.1
-
99
-
-
0023280351
-
Denosologization of biological psychiatry or the specificity of 5-HT disturbances in psychiatric disorders
-
Van Praag HM, Kahn RS, Asnis GM. Denosologization of biological psychiatry or the specificity of 5-HT disturbances in psychiatric disorders. J Affect Disord. 1987 ; 13: 1-8
-
(1987)
J Affect Disord
, vol.13
, pp. 1-8
-
-
Van Praag, H.M.1
Kahn, R.S.2
Asnis, G.M.3
-
100
-
-
0037331104
-
The antidepressant-like effects of neurokinin NK1 receptor antagonists in a gerbil tail suspension test
-
Varty GB, Cohen-Williams ME, Hunter JC. The antidepressant-like effects of neurokinin NK1 receptor antagonists in a gerbil tail suspension test. Behav Pharmacol. 2003 ; 14: 87-95
-
(2003)
Behav Pharmacol
, vol.14
, pp. 87-95
-
-
Varty, G.B.1
Cohen-Williams, M.E.2
Hunter, J.C.3
-
102
-
-
0037051872
-
Placebo response in studies of major depression: Variable, substantial, and growing
-
Walsh BT, Seidman SN, Sysko R, et al. Placebo response in studies of major depression: Variable, substantial, and growing. JAMA. 2002 ; 287: 1840-1847
-
(2002)
JAMA
, vol.287
, pp. 1840-1847
-
-
Walsh, B.T.1
Seidman, S.N.2
Sysko, R.3
-
103
-
-
79958056690
-
Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants: Prediction for efficacy in animal models of neuropathic pain?
-
Wattiez A-S, Libert F, Privat A-M, et al. Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants: Prediction for efficacy in animal models of neuropathic pain?. Br J Pharmacol. 2011 ; 163: 792-803
-
(2011)
Br J Pharmacol
, vol.163
, pp. 792-803
-
-
Wattiez, A.-S.1
Libert, F.2
Privat, A.-M.3
-
104
-
-
0025188672
-
Neurobehavioral studies of forced swimming: The role of learning and memory in the forced swim test
-
West AP. Neurobehavioral studies of forced swimming: the role of learning and memory in the forced swim test. Prog Neuropsychopharmacol Biol Psychiatry. 1990 ; 14: 863-877
-
(1990)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.14
, pp. 863-877
-
-
West, A.P.1
-
105
-
-
0021348560
-
The validity of animal models of depression
-
Willner P. The validity of animal models of depression. Psychopharmacology. 1984 ; 83: 1-16
-
(1984)
Psychopharmacology
, vol.83
, pp. 1-16
-
-
Willner, P.1
-
106
-
-
0031440325
-
Validity, reliability and utility of the chronic mild stress model of depression: A 10-year review and evaluation
-
Willner P. Validity, reliability and utility of the chronic mild stress model of depression: A 10-year review and evaluation. Psychopharmacology. 1997 ; 134: 319-329
-
(1997)
Psychopharmacology
, vol.134
, pp. 319-329
-
-
Willner, P.1
-
107
-
-
0023636527
-
Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant
-
Willner P, Towell A, Sampson D, et al. Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant. Psychopharmacology. 1987 ; 93: 358-364
-
(1987)
Psychopharmacology
, vol.93
, pp. 358-364
-
-
Willner, P.1
Towell, A.2
Sampson, D.3
-
108
-
-
1242263295
-
From monoamines to genomic targets: A paradigm shift for drug discovery in depression
-
Wong ML, Licinio J. From monoamines to genomic targets: A paradigm shift for drug discovery in depression. Nat Rev Drug Discov. 2004 ; 3: 136-151
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 136-151
-
-
Wong, M.L.1
Licinio, J.2
-
109
-
-
39649084919
-
The FDA Critical Path Initiative and its influence on new drug development
-
Woodcock J, Woosley R. The FDA Critical Path Initiative and its influence on new drug development. Ann Rev Med. 2008 ; 59: 1-12
-
(2008)
Ann Rev Med
, vol.59
, pp. 1-12
-
-
Woodcock, J.1
Woosley, R.2
-
111
-
-
19344373591
-
Effects of desipramine and tramadol in a chronic mild stress model in mice are altered by yohimbine but not by pindolol
-
Yalcin I, Aksu F, Belzung C. Effects of desipramine and tramadol in a chronic mild stress model in mice are altered by yohimbine but not by pindolol. Eur J Pharmacol. 2005 ; 514: 165-174
-
(2005)
Eur J Pharmacol
, vol.514
, pp. 165-174
-
-
Yalcin, I.1
Aksu, F.2
Belzung, C.3
-
112
-
-
26044460006
-
The ascent of mouse: Advances in modelling human depression and anxiety
-
Cryan JF, Holmes A. The ascent of mouse: Advances in modelling human depression and anxiety. Nat Rev Drug Discov. 2005 ; 4: 775-790
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 775-790
-
-
Cryan, J.F.1
Holmes, A.2
-
113
-
-
77956319341
-
An integrative and functional framework for the study of animal emotion and mood
-
Mendl M, Burman OH, Paul ES. An integrative and functional framework for the study of animal emotion and mood. Proc Biol Sci. 2010 ; 277: 2895-2904
-
(2010)
Proc Biol Sci
, vol.277
, pp. 2895-2904
-
-
Mendl, M.1
Burman, O.H.2
Paul, E.S.3
-
115
-
-
26044460006
-
The ascent of mouse: Advances in modelling human depression and anxiety
-
Cryan JF, Holmes A. The ascent of mouse: Advances in modelling human depression and anxiety. Nat Rev Drug Discov. 2005 ; 4: 785-790
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 785-790
-
-
Cryan, J.F.1
Holmes, A.2
-
116
-
-
77649338497
-
Depression as an evolutionary adaptation: Anatomical organisation around the third ventricle
-
Hendrie CA, Pickles AR. Depression as an evolutionary adaptation: Anatomical organisation around the third ventricle. Med Hypotheses. 2010 ; 74: 735-740
-
(2010)
Med Hypotheses
, vol.74
, pp. 735-740
-
-
Hendrie, C.A.1
Pickles, A.R.2
-
117
-
-
57649140590
-
Removing obstacles in neuroscience drug discovery: The future path for animal models
-
Markou A, Chimmulera C, Geyer MA, et al. Removing obstacles in neuroscience drug discovery: The future path for animal models. Neuropsychopharmacology. 2009 ; 34: 74-89
-
(2009)
Neuropsychopharmacology
, vol.34
, pp. 74-89
-
-
Markou, A.1
Chimmulera, C.2
Ma, G.3
-
118
-
-
0028215395
-
The social competition hypothesis of depression
-
Price J, Sloman L, Gardner R, et al. The social competition hypothesis of depression. Br J Psychiatry. 1998 ; 164: 309-315
-
(1998)
Br J Psychiatry
, vol.164
, pp. 309-315
-
-
Price, J.1
Sloman, L.2
Gardner, R.3
-
119
-
-
0021348560
-
The validity of animal models of depression
-
Willner P. The validity of animal models of depression. Psychopharmacology. 1984 ; 83: 1-16
-
(1984)
Psychopharmacology
, vol.83
, pp. 1-16
-
-
Willner, P.1
-
120
-
-
0036328118
-
The validity of animal models of predisposition to depression
-
Willner P, Mitchell PJ. The validity of animal models of predisposition to depression. Behav Pharmacol. 2002 ; 13: 169-188
-
(2002)
Behav Pharmacol
, vol.13
, pp. 169-188
-
-
Willner, P.1
Mitchell, P.J.2
|