Polyethylene glycol-modified gelatin/polylactic acid nanoparticles for enhanced photodynamic efficacy of a hypocrellin derivative in vitro

Journal of Biomedical Nanotechnology

Volumn 9, Issue 2, 2013, Pages 177-192

  Babu, Anish ^a   Periasamy, Jayaprakash ^a   Gunasekaran, Amsaveni ^b   Kumaresan, Ganesan ^a   Naicker, Selvaraj ^c   Gunasekaran, Paramasamy ^a   Murugesan, Ramachandran ^a,b  

^a MADURAI KAMARAJ UNIVERSITY   (India)

^b CHETTINAD HOSPITAL AND RESEARCH INSTITUTE   (India)

^c Innovative Health and Energy Technologies Inc   (Canada)

Author keywords

Hypocrellin; Nanoparticles; Photodynamic Therapy; Phototoxicity; Polyethyleneglycol Modified Gelatin; Polylactic Acid

Indexed keywords

BIODEGRADABLE NANOPARTICLE; CONTROLLED DRUG RELEASE; HYPOCRELLIN; PHOTO-TOXICITY; PHOTODYNAMIC EFFICACY; PHOTODYNAMIC THERAPY (PDT); POLY LACTIC ACID; REACTIVE OXYGEN SPECIES;

BIOPOLYMERS; CELL CULTURE; CELL DEATH; LOADING; PHOTODYNAMIC THERAPY;

NANOPARTICLES;

CYCLOHEXANE 1,2 DIAMINO HYPOCRELLIN B; GELATIN; HYPOCRELLIN B; MACROGOL; NANOPARTICLE; POLYLACTIC ACID; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST ADENOCARCINOMA; CANCER CELL; CONTROLLED DRUG RELEASE; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOMA; PHOTODYNAMIC THERAPY; PHOTODYNAMICS; PHOTOTOXICITY; STOMACH SARCOMA;

ANIMALS; CELL DEATH; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; GELATIN; HUMANS; LACTIC ACID; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICROSCOPY, ATOMIC FORCE; MICROSCOPY, FLUORESCENCE; NANOPARTICLES; PARTICLE SIZE; PERYLENE; PHOTOBLEACHING; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; POLYETHYLENE GLYCOLS; POLYMERS; QUINONES; REACTIVE OXYGEN SPECIES; SPECTROPHOTOMETRY, ULTRAVIOLET; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TREATMENT OUTCOME;

EID: 84876537675     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2013.1480     Document Type: Article

References (56)

1. M. Ferrari, Cancer nanotechnology: Opportunities and challenges. Nat. Rev. Cancer 5, 161 (2005).
2. K. Cho, X. Wang, S. Nie, Z. Chen, and D. M. Shi, Therapeutic nanoparticles for drug delivery in cancer. Clin. Cancer. Res. 14, 1310 (2008).
3. R. S. Dothager and D. P. Worms, Nano in cancer: Linking chemistry, biology, and clinical applications in vivo, Cancer. Res. 71, 1 (2011).
4. Z. Hou, H. Wei, Q. Wang, Q. Sun, C. Zhou, C. Zhan, X. Tang, and Q. Zhang, New method to prepare mitomycin C loaded PLAnanoparticles with high drug entrapment efficiency. Nanoscale. Res. Lett. 4, 732 (2009).
5. D. Peer, J. M. Karp, S. Hong, O. C. Farokhzad, R. Margalit, and R. Langer, Nanocarriers as an emerging platform for cancer therapy. Nat. Nanotechnol. 2, 751 (2007).
6. H. Maeda, J. Wu, T. Sawa, Y. Matsumura, and K. Hori, Tumor vascular permeability and the EPR effect in macromolecular therapeutics: A review. J. Control. Rel. 65, 271 (2000).
7. S. H. Jang, M. G. Wientjes, D. Lu, J. L.-S. Au, Drug delivery and transport to solid tumors. Pharm. Res. 20, 1337 (2003).
8. T. J. Dougherty, C. J. Gomer, B. W. Henderson, G. Jori, D. Kessel, M. Korbelik, J0. Moan, and Q. Peng, Photodynamic therapy. J. Natl. Cancer. Inst. 90, 889 (1998).
9. P. Agostinis, K. Berg, K. A. Cengel, T. H. Foster, A. W. Girotti, S. O. Gollnick, S. M. Hahn, M. R. Hamblin, A. Juzeniene, D. Kessel, M. Korbelik, J. Moan, P. Mroz, D. Nowis, J. Piette, B. C. Wilson, and J. Golab, Photodynamic therapy of cancer: An update. CA: Cancer. J. Clin. 61, 250 (2011).
10. D. K. Chatterjee, L. S. Fong, and Y. Zhang, Nanoparticles in photodynamic therapy: An emerging paradigm. Adv. Drug. Deliv. Rev. 15, 1627 (2008).
11. D. Fayter, M. Corbett, M. Heirs, D. Fox, and A. Eastwood, A systematic review of photodynamic therapy in the treatment of precancerous skin conditions, barrett's oesophagus and cancers of the biliary tract, brain, head and neck, lung, oesophagus and skin. Health. Technol. Assess. 14, 1 (2010).
12. A. Ferrario, S. Lim, F. Xu, M. Luna, K. J. Gaffney, N. A. Petasis. A. H. Schönthal, and C. J. Gomer, Enhancement of photodynamic therapy by 2, 5-dimethyl celecoxib, a non-cyclooxygenase-2 inhibitor analog of celecoxib. Cancer. Lett. 304, 33 (2011).
13. K. Wang, Q. He, X. Yan, Y. Cui, W. Qi, L. Duana, and J. Li, Encapsulated photosensitive drugs by biodegradable microcapsules to incapacitate cancer cells. J. Mater. Chem. 17, 4018 (2007).
14. Z. Zhou, L. Zhang, H. Liu, Q. Zhang, B. Liu, P. Ai, H. Ma, W. Liu, Z. Li, W. Sheng, Y. Zeng, and R. Zhong, Photocytotoxicity of hypocrellin B (HB) was enhanced by liposomalization in vitro. Int. J. Toxicol. 30, 174 (2011).
15. H. Ding, B. D. Sumer, C. W. Kessinger, Y. Dong, G. Huang, D. A. Boothman, and J. Gao, Nanoscopic micelle delivery improves the photophysical properties and efficacy of photodynamic therapy of protoporphyrin IX. J. Control. Release. 151, 271 (2011).
16. Y. Yang, W. Song, A. Wang, P. Zhu, J. Fei, and J. Li, Lipid coated mesoporous silica nanoparticles as photosensitive drug carriers. Phys. Chem. Chem. Phys. 12, 4418 (2010).
17. M. Fadel, K. Kassab, and D. A. Fadeel, Zinc phthalocyanine-loaded PLGA biodegradable nanoparticles for photodynamic therapy in tumor-bearing mice. Lasers Med. Sci. 25, 283 (2010).
18. 2 and 1O2-. Photochem. Photobiol. Sci. 2, 871 (2003).
19. C. Yu, S. Chen, M. Zhang, and T. Shen, Spectroscopic studies and photodynamic actions of hypocrellin B in liposomes. Photochem. Photobiol. 73, 482 (2001).
20. S. Xu, S. Chen, M. Zhang, T. Shen, Y. Zhao, Z. Liu, and Y. Wu, Butylamino-demethoxy-hypocrellins and photodynamic therapy decreases human cancer in vitro and in vivo. Biochim. Biophys. Acta. 1537, 222 (2001).
21. B. T. Paul, M. S. Babu, T. R. Santhoshkumar, D. Karunagaran, G. S. Selvam, K. Brown, T. Woo, S. Sharma, S. Naicker, and R. Murugesan, Biophysical evaluation of two red-shifted hypocrellin B derivatives as novel PDT agents. J. Photochem. Photobiol B. 94, 38 (2009).
22. I. Stamati, M. K. Kuimova, M. Lion, G. Yahioglu, D. Phillips, and M. P. Deonarain, Novel photosensitisers derived from pyropheophorbide-a: Uptake by cells and photodynamic efficiency in vitro. Photochem. Photobiol. Sci. 9, 1033 (2010).
23. S. Kommareddy and M. Amiji, Poly (ethylene glycol)-modified thiolated gelatin nanoparticles for glutathione-responsive intracellular DNA delivery. Nanomedicine 3, 32 (2007).
24. B. Anish, K. Jeyasubramanian, P. Gunasekaran, and R. Murugesan, Gelatin nanocarrier enables efficient delivery and phototoxicity of hypocrellin B against a mice tumour model. J. Biomed. Nanotechnol. 8, 43 (2012).
25. X. Zheng, B. Kan, M. Gou, S. Fu, J. Zhang, K. Men, L. Chen, F. Luo, Y. Zhao, X. Zhao, Y. Wei, and Z. Qian, Preparation of MPEG-PLA nanoparticles for Honokiol delivery in vitro. Int. J. Pharm. 382, 262 (2010).
26. H. Valo, L. Peltonen, S. Vehviläinen, M. Karjalainen, R. Kostiainen, T. Laaksonen, and J. Hirvonen, Electrospray encapsulation of hydrophilic and hydrophobic drugs in poly(L-lactic acid) nanoparticles. Small 5, 1791 (2009).
27. Z. Lu, T. K. Yeh, J. Wang, L. Chen, G. Lyness, Y. Xin, M. G. Wientjes, V. Bergdall, G. Couto, F. A. Berger, C. E. Kosarek, and J. L. Au, Paclitaxel gelatin nanoparticles for intravesical bladder cancer therapy. J. Urol. 185, 1478 (2011).
28. R. Kumar, R. C. Nagarwal, M. Dhanawat, and J. K. Pandit, In-vitro and in-vivo study of indomethacin loaded gelatin nanoparticles. J. Biomed. Nanotechnol. 7, 325 (2011).
29. X. B. Yuan, Y. B. Yuan, W. Jiang, J. Liu, E. J. Tian, H. M. Shunc, D. H. Huanga, X. Y. Yuan, H. Li, and J. Sheng, Preparation of rapamycin-loaded chitosan/PLA nanoparticles for immunosuppression in corneal transplantation. Int. J. Pharm. 349, 241 (2008).
30. S. J. Snyder and P. Z. Sobcinski, An improved 2,4,6-Trinitro Benzene Sulphonic Acid method for the determination of amines. Anal. Biochem. 64, 284 (1975).
31. S. B. Wang, A. Z. Chen, L. J. Weng, M. Y. Chen, and X. L. Xie, Effect of drug-loading methods on drug load, encapsulation efficiency and release properties of alginate/poly-L-arginine/chitosan ternary complex microcapsules. Macromol. Biosci. 4, 27 (2004).
32. G. Shazly, T. Nawroth, and P. Langguth, Comparison of dialysis and dispersion methods for in vitro release determination of drugs from multilamellar liposomes. Dissol. Technol. 15, 7 (2008).
33. Y. Guo, S. Rogelj, and P. Zhang, Rose bengal decorated silica nanoparticles as photosensitizers for inactivation of gram positive bacteria. Nanotechnology 21, 065102 (2010).
34. W. H. Koppenol and J. Butler, The radiation chemistry of cytochrome C. Isr. J. Chem. 24, 14 (1984).
35. S. Schubert, J. T. Jr. Delaney, and U. S. Schubert, Nanoprecipitation and nanoformulation of polymers: From history to powerful possibilities beyond poly(lactic acid). Soft Matter. 7, 1581 (2011).
36. M. T. Peracchia, C. Vauthier, D. Desmaele, A. Gulik, J. C. Dedieu, J. d'Angelo, and P. Couvreur, Pegylated nanoparticles from a novel methoxypolyethylene glycol cyanoacrylate-hexadecyl cyanoacrylate amphiphilic copolymer. Pharm. Res. 15, 550 (1998).
37. R. K. Jain, Delivery of molecular and cellular medicine to solid tumors. Adv. Drug Deliv. Rev. 46, 149 (2001).
38. J. Klesing, A. Wiehe, B. Gitter, S. Graffe, and M. Epple, Positively charged calcium phosphate/polymer particles for photodynamic therapy. J. Mater. Sci. 21, 887 (2010).
39. Y. N. Konan, R. Cerny, J. Favet, M. Berton, R. Gurny, and E. Allemann, Preparation and characterization of sterile sub- 200 nm meso-tetra(4- hydroxylphenyl) porphyrin-loaded nanoparticles for photodynamic therapy. Eur. J. Pharm. Biopharm. 55, 115 (2003).
40. V. J. Mohanraj and Y. Chen, Nanoparticles-a review. Trop. J. Pharm. Res. 5, 561 (2006).
41. T. Govender, T. Riley, T. Ehtezazi, M. C. Garnett, S. Stolnik, L. Illum, and S. S. Davis, Defining the drug incorporation properties of PLA-PEG nanoparticles. Int. J. Pharm. 199, 95 (2000).
42. A. Budhian, S. J. Seigel, and K. I. Winey, Haloperidol-loaded PLGA nanoparticles: Systematic study of particle size and drug content. Int. J. Pharm. 336, 367 (2007).
43. Y. Tareq, M. Fadel, R. Fahmy, and K. Kassab, Evaluation of hypericin-loaded solid lipid nanoparticles: Physicochemical properties, photostability and phototoxicity. Pharm. Dev. Technol. 17, 177 (2012).
44. E. Ricci-Junior and J. M. Marchetti, Zinc(II) phthalocyanine loaded PLGA nanoparticles for photodynamic therapy use. Int. J. Pharm. 310, 187 (2006).
45. Y. Hu, X. Jiang, Y, Ding, L. Zhang, C. Yang, J. Zhang, J. Chen, and Y. Yang, Preparation and drug release behaviors of nimodipine-loaded poly(caprolactone)-poly(ethylene oxide)- polylactide amphiphilic copolymer nanoparticles. Biomaterials 24, 2395 (2003).
46. S. Mallick, K. Roy, A. Chakraborty, and S. Saha, Mechanissm of in vitro release kinetics of Flurbiprofen loaded ethyl cellulose micropellets. Acta Poloniae. Pharmaceutica. Drug Res. 59, 193 (2002).
47. Z. Yang, W. T. S. Huck, S. M. Clarke, A. R. Tajbakhsh, and E. M. Terentjev, Shape-memory nanoparticles from inherently nonspherical polymer colloids. Nat. Mater. 4, 486 (2005).
48. 4 nanoparticles, IEEE T. Magn. 39, 2198 (2003).
49. H. J. Hah, G. Kim, Y. E. Lee, D. A. Orringer, O. Sagher, M. A. Philbert, and R. Kopelman, Methylene blue-conjugated hydrogel nanoparticles and tumor-cell targeted photodynamic therapy. Macromol. Biosci. 11, 90 (2011).
50. J. R. Khurma, D. R. Rohindra, and R. Dev, Miscibility study of solution cast blends of poly(lactic acid) and poly(vinyl butyral), south-pacific. J. Nat. Appl. Sci. 23, 22 (2005).
51. K. Ofokansi, G. Winter, G. Fricker, and C. Coester, Matrix-loaded biodegradable gelatin nanoparticles as new approach to improve drug loading and delivery. Eur. J. Pharm. Biopharm. 76, 1 (2010).
52. Z. Li, J. Wang, J. Chen, W. Lei, X. Wang, and B. Zhang, pH-responsive silica nanoparticles for controllable 1O2 generation. Nanotechnology 21, 115102 (2010).
53. M. J. Shieh, C. Y. Hsu, L. Y. Huang, H. Y. Chen, F. H. Huang, and P. S. Lai, Reversal of doxorubicin-resistance by multifunctional nanoparticles in MCF-7/ADR cells. J. Control Rel. 152, 418 (2011).
54. A. Khdair, B. Gerard, H. Handa, G. Mao, M. P. V. Shekhar, and J. Panyam, Surfactant-polymer nanoparticles enhance the effectiveness of anticancer photodynamic therapy. Mol. Pharm. 5, 795 (2008).
55. Z. L. Magali, N. Lange, R. Gurny, and F. Delie, Hypericin-loaded nanoparticles for the photodynamic treatment of ovarian cancer. Int. J. Pharm. 326, 174 (2006).
56. A. Mirossay, J. Moizis, J. Tothova, M. Hajikova, A, Lackova, and L. Mirossay, Hypocrellin and hypericin-induced phototoxicity of HL-60 cells: Apoptosis or necrosis?. Phytomedicine 7, 471 (2000).