In-Vitro and In-Vivo study of indomethacin loaded gelatin nanoparticles

Journal of Biomedical Nanotechnology

Volumn 7, Issue 3, 2011, Pages 325-333

  Kumar, Rakesh ^a   Nagarwal, Ramesh C ^a   Dhanawat, Meenakshi ^a   Pandit, Jayanta Kumar ^a  

^a BANARAS HINDU UNIVERSITY   (India)

Author keywords

Bioavailability; Gelatin A and B; Indomethacin; IVIVC; Nanoparticles

Indexed keywords

ANTI-INFLAMMATORY ACTIVITY; BIOAVAILABILITY; BURST RELEASE; CONTROLLED RELEASE; DESOLVATION; DRUG LOADED NANOPARTICLE; DRUG RELEASE; DRUG SOLUTIONS; DRUG-POLYMER INTERACTION; DSC STUDIES; ENTRAPMENT EFFICIENCY; FTIR; GELATIN NANOPARTICLES; HIGUCHI MODEL; IN-VITRO; IN-VIVO; INDOMETHACIN; IVIVC; KINETIC MODELS; PEPPAS MODEL; PHARMACOKINETIC PARAMETERS; PHARMACOKINETIC STUDIES; POLYDISPERSITY INDICES; POLYMERIC PARTICLES; RELATIVE BIOAVAILABILITY; RELEASE PATTERN; SUBMICRON; VITRO-IN VIVO CORRELATION;

BIOCHEMISTRY; CONTROLLED DRUG DELIVERY; DRUG INTERACTIONS; PHARMACOKINETICS; POLYDISPERSITY; POLYMERS;

NANOPARTICLES;

GELATIN; INDOMETACIN; NANOPARTICLE;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; AREA UNDER THE CURVE; ARTICLE; ATOMIC FORCE MICROSCOPY; CONTROLLED RELEASE FORMULATION; DRUG BIOAVAILABILITY; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; MORPHOLOGY; NANOFABRICATION; NONHUMAN; PARTICLE SIZE; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION; ULTRAVIOLET SPECTROSCOPY; ZETA POTENTIAL; ANIMAL; DELAYED RELEASE FORMULATION; KINETICS; ORAL DRUG ADMINISTRATION; WISTAR RAT;

ADMINISTRATION, ORAL; ANIMALS; DELAYED-ACTION PREPARATIONS; DRUG STABILITY; GELATIN; INDOMETHACIN; KINETICS; NANOPARTICLES; PARTICLE SIZE; RATS; RATS, WISTAR;

EID: 80052304918     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2011.1290     Document Type: Article

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