Oligoclonal bands and cerebrospinal fluid markers in multiple sclerosis: Associations with disease course and progression

Multiple Sclerosis Journal

Volumn 19, Issue 5, 2013, Pages 577-584

  Lourenco, Pedro ^a   Shirani, Afsaneh ^a   Saeedi, Jameelah ^a   Oger, Joel ^a,b,c   Schreiber, William E ^b,c   Tremlett, Helen ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b VANCOUVER GENERAL HOSPITAL   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

cerebrospinal fluid; chronic progressive; CNS; demyelinating autoimmune diseases; ethnicity; multiple sclerosis; natural history studies (prognosis); oligoclonal IgG; prognosis; relapsing remitting multiple sclerosis

Indexed keywords

IMMUNOGLOBULIN G; OLIGOCLONAL BAND;

ADULT; ARTICLE; CEREBROSPINAL FLUID ANALYSIS; DISABILITY SEVERITY; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE MARKER; ETHNICITY; EXPANDED DISABILITY STATUS SCALE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; RETROSPECTIVE STUDY;

EID: 84876517388     PISSN: 13524585     EISSN: 14770970     Source Type: Journal    
DOI: 10.1177/1352458512459684     Document Type: Article

References (37)

1. Ford HL, Gerry E, Johnson M, et al. A prospective study of the incidence, prevalence and mortality of multiple sclerosis in Leeds. J Neurol. 2002 ; 249: 260-265
2. Farrell MA, Kaufmann JC, Gilbert JJ, et al. Oligoclonal bands in multiple sclerosis: clinical-pathologic correlation. Neurology. 1985 ; 35: 212-218
3. Sorensen TL, Tani M, Jensen J, et al. Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients. J Clin Invest. 1999 ; 103: 807-815
4. Bourahoui A, De Seze J, Guttierez R, et al. CSF isoelectrofocusing in a large cohort of MS and other neurological diseases. Eur J Neurol. 2004 ; 11: 525-529
5. Franciotta D, Bergamaschi R, Amato MP, et al. Clinical correlations of CSF single IgG bands. J Neurol. 2005 ; 252: 1274-1275
6. Link H, Huang YM. Oligoclonal bands in multiple sclerosis cerebrospinal fluid: an update on methodology and clinical usefulness. J Neuroimmunol. 2006 ; 180: 17-28
7. Poser CM, Paty DW, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol. 1983 ; 13: 227-231
8. McDonald WI, Compston A, Edan G, et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol. 2001 ; 50: 121-127
9. Polman CH, Reingold SC, Edan G, et al. Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria". Ann Neurol. 2005 ; 58: 840-846
10. Poser CM, Brinar VV. The accuracy of prevalence rates of multiple sclerosis: a critical review. Neuroepidemiology. 2007 ; 29: 150-155
11. Kuroiwa Y, Hung TP, Landsborough D, et al. Multiple sclerosis in Asia. Neurology. 1977 ; 27: 188-192
12. Imrell K, Landtblom AM, Hillert, et al. Multiple sclerosis with and without CSF bands: clinically indistinguishable but immunogenetically distinct. Neurology. 2006 ; 67: 1062-1064
13. Kikuchi S, Fukazawa T, Niino M, et al. HLA-related subpopulations of MS in Japanese with and without oligoclonal IgG bands. Human leukocyte antigen. Neurology. 2003 ; 60: 647-651
14. Fukazawa T, Kikuchi S, Sasaki H, et al. The significance of oligoclonal bands in multiple sclerosis in Japan: relevance of immunogenetic backgrounds. J Neurol Sci. 1998 ; 158: 209-214
15. Trojano M, Logroscino GC, Pisicchio L, et al. The Multiple Sclerosis Cooperative Etiological Study in Italy: preliminary analysis of CSF findings. Ital J Neurol Sci. 1987 ;: 71-76
16. Siritho S, Freedman MS. The prognostic significance of cerebrospinal fluid in multiple sclerosis. J Neurol Sci. 2009 ; 279: 21-25
17. Pirttila T, Nurmikko T. CSF oligoclonal bands, MRI, and the diagnosis of multiple sclerosis. Acta Neurol Scand. 1995 ; 92: 468-471
18. Stendahl-Brodin L, Link H. Relation between benign course of multiple sclerosis and low-grade humoral immune response in cerebrospinal fluid. J Neurol Neurosurg Psychiatry. 1980 ; 43: 102-105
19. Zeman AZ, Kidd D, McLean BN, et al. A study of oligoclonal band negative multiple sclerosis. J Neurol Neurosurg Psychiatry. 1996 ; 60: 27-30
20. Koch M, Heersema D, Mostert J, et al. Cerebrospinal fluid oligoclonal bands and progression of disability in multiple sclerosis. Eur J Neurol. 2007 ; 14: 797-800
21. Canada S, ed. 2010 :
22. Blennow K, Fredman P, Wallin A, et al. Protein analysis in cerebrospinal fluid. II. Reference values derived from healthy individuals 18-88 years of age. Eur Neurol. 1993 ; 33: 129-133
23. Pender MP. The pathogenesis of primary progressive multiple sclerosis: antibody-mediated attack and no repair?. J Clin Neurosci. 2004 ; 11: 689-692
24. Sola P, Mandrioli J, Simone AM, et al. Primary progressive versus relapsing-onset multiple sclerosis: presence and prognostic value of cerebrospinal fluid oligoclonal IgM. Mult Scler J. 2011 ; 17: 303-311
25. Freedman MS, Thompson EJ, Deisenhammer F, et al. Recommended standard of cerebrospinal fluid analysis in the diagnosis of multiple sclerosis: a consensus statement. Arch Neurol. 2005 ; 62: 865-870
26. Verjans E, Theys P, Delmotte P, et al. Clinical-parameters and intrathecal IGG synthesis as prognostic features in multiple-sclerosis.1. Journal of Neurology. 1983 ; 229: 155-165
27. Joseph FG, Hirst CL, Pickersgill TP, et al. CSF oligoclonal band status informs prognosis in multiple sclerosis: a case control study of 100 patients. J Neurol Neurosurg Psychiatry. 2009 ; 80: 292-296
28. Izquierdo G, Angulo S, Garcia-Moreno JM, et al. Intrathecal IgG synthesis: marker of progression in multiple sclerosis patients. Acta Neurol Scand. 2002 ; 105: 158-163
29. Shirani A, Zhao Y, Karim ME, et al. Association between use of interferon beta and progression of disability in patients with relapsing-remitting multiple sclerosis. JAMA. 2012 ; 308: 247-256
30. Lunding J, Midgard R, Vedeler CA. Oligoclonal bands in cerebrospinal fluid: a comparative study of isoelectric focusing, agarose gel electrophoresis and IgG index. Acta Neurol Scand. 2000 ; 102: 322-325
31. Link H, Kostulas V. Utility of isoelectric focusing of cerebrospinal fluid and serum on agarose evaluated for neurological patients. Clin Chem. 1983 ; 29: 810-815
32. McLean BN, Luxton RW, Thompson EJ. A study of immunoglobulin G in the cerebrospinal fluid of 1007 patients with suspected neurological disease using isoelectric focusing and the Log IgG-Index. A comparison and diagnostic applications. Brain. 1990 ; 113 (Pt 5). 1269-1289
33. Sa MJ, Sequeira L, Rio ME, et al. Oligoclonal IgG bands in the cerebrospinal fluid of portuguese patients with multiple sclerosis: negative results indicate benign disease.. Arq Neuropsiquiatr. 2005 ; 63: 375-379
34. da Gama PD, Machado Ldos R, Livramento JA, et al. Study of oligoclonal bands restricted to the cerebrospinal fluid in multiple sclerosis patients in the city of Sao Paulo. Arq Neuropsiquiatr. 2009 ; 67: 1017-1022
35. Romero-Pinel L, Martinez-Yelamos S, Bau L, et al. Association of HLA-DRB1*15 allele and CSF oligoclonal bands in a Spanish multiple sclerosis cohort. Eur J Neurol. 2011 ; 18: 1258-1262
36. Hockertz MK, Paty DW, Beall SS. Susceptibility to relapsing-progressive multiple sclerosis is associated with inheritance of genes linked to the variable region of the TcR beta locus: use of affected family-based controls. Am J Hum Genet. 1998 ; 62: 373-385
37. Asgari N, Lillevang ST, Skejoe HP, et al. A population-based study of neuromyelitis optica in Caucasians. Neurology. 2011 ; 76: 1589-1595