Development of synthetic routes, via a tropinone intermediate, to a long-acting muscarinic antagonist for the treatment of respiratory disease

Organic Process Research and Development

Volumn 17, Issue 4, 2013, Pages 641-650

  Bream, Robert N ^a,b   Hayes, Doug ^a   Hulcoop, David G ^a   Whiteman, Alexandra J ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b EUROPEAN MEDICINES AGENCY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BUILDING BLOCKES; CHRONIC OBSTRUCTIVE PULMONARY DISEASE; CLINICAL TRIAL; EPOXIDE REDUCTION; REACTION CONDITIONS; SAFETY ASSESSMENTS; SYNTHETIC ROUTES;

PULMONARY DISEASES;

SUBSTRATES;

EID: 84876517281     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op3002933     Document Type: Article

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