Synthesis and resolution of the benzomorphan-based kappa opioid agonist bremazocine

Synthesis

Volumn , Issue 10, 2007, Pages 1481-1484

  Thomas, James B ^a   Brieaddy, Lawrence E ^a   Boldt, Karl G ^a   Perretta, Carin ^a   Carroll, F Ivy ^a  

^a RTI INTERNATIONAL   (United States)

Author keywords

Bremazocine; Kappa opioid agonist; Medicinal chemistry; Receptors; Synthesis

Indexed keywords

KAPPA OPIOID AGONIST; MEDICINAL CHEMISTRY; RECEPTORS;

AMMONIUM COMPOUNDS; HYDROCHLORIC ACID; SALTS; SYNTHESIS (CHEMICAL);

DRUG PRODUCTS;

2 (4 METHOXYBENZYL) 1,3 DIMETHYL 2,3 DIHYDROPYRIDIN 4 (1H)ONE; 2 (4 METHOXYBENZYL) 1,3,3 TRIMETHYL 2,3 DIHYDROPYRIDIN 4 (1H)ONE; 2 (4 METHOXYBENZYL) 1,3,3 TRIMETHYLPIPERIDIN 4 ONE; 3 BROMOCAMPHORSULFONIC ACID; 4 ETHYL 2 (4 METHOXYBENZYL) 1,3,3 TRIMETHYLPIPERIDIN 4 OL; 6 ETHYL 11,11 DIMETHYL 1,2,3,4,5,6 HEXAHYDRO 2,6 METHANO 3 BENZAZOCIN 8 OL; 6 ETHYL 3,11,11 TRIMETHYL 1,2,3,4,5,6 HEXAHYDRO 2,6 METHANO 3 BENZAZOCIN 8 OL; BENZAZOCINE DERIVATIVE; BENZOMORPHAN; BREMAZOCINE; DIHYDROPYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS;

EID: 34249805079     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-966026     Document Type: Article

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