Nanobiotechnological approaches to delivery of DNA vaccine against fungal infection

Journal of Biomedical Nanotechnology

Volumn 9, Issue 2, 2013, Pages 221-230

  Ribeiro, A M ^a   Souza, A C O ^a   Amaral, A C ^b   Vasconcelos, N M ^a   Jeronimo M S ^a   Carneiro, F P ^a   Faccioli, L H ^c   Felipe, M S S ^a   Silva, C L ^d   Bocca, A L ^a  

^a UNIVERSITY OF BRASILIA   (Brazil)

^b FEDERAL UNIVERSITY OF GOIÁS   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d Farmacore Biotecnology Ltd   (Brazil)

Author keywords

DNA Vaccines; DNAhsp65 PLGA; Liposomal DNAhsp65; Paracoccidioides Brasiliensis; Systemic Mycosis

Indexed keywords

DNA VACCINE; DNAHSP65 PLGA; LIPOSOMAL DNAHSP65; PARACOCCIDIOIDES BRASILIENSIS; SYSTEMIC MYCOSIS;

COPOLYMERS; DRUG THERAPY; IMMUNE SYSTEM; LIPOSOMES;

VACCINES;

DNA VACCINE; GAMMA INTERFERON; HEAT SHOCK PROTEIN 65; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 4; LIPOSOME;

ADJUVANT THERAPY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG FORMULATION; HUMORAL IMMUNITY; LUNG INFECTION; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; NANOBIOTECHNOLOGY; NONHUMAN; SOUTH AMERICAN BLASTOMYCOSIS;

ANIMALS; BACTERIAL PROTEINS; BIOTECHNOLOGY; CELL PROLIFERATION; CHAPERONIN 60; CYTOKINES; FUNGAL VACCINES; GENE TRANSFER TECHNIQUES; IMMUNITY, HUMORAL; IMMUNOGLOBULIN G; LACTIC ACID; LIPOSOMES; LUNG; MALE; MICE; MICE, INBRED BALB C; MYCOBACTERIUM LEPRAE; NANOTECHNOLOGY; NITRIC OXIDE; PARACOCCIDIOIDES; PARACOCCIDIOIDOMYCOSIS; POLYGLYCOLIC ACID; SPLEEN; VACCINES, DNA;

EID: 84876512261     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2013.1491     Document Type: Article

References (45)

1. J. E. Cutler, G. S. Deepe, Jr, and B. S. Klein, Advances in combating fungal diseases: Vaccines on the threshold. Nat. Rev. Microbiol. 5, 13 (2007).
2. A. M. Ribeiro, A. L. Bocca, A. C. Amaral, L. H. Faciolli, F. Galetti F, C. R. Zárate-Bladés, F. Figueiredo, C. L. Silva, and M. S. S. Felipe, DNAhsp65 vaccination induces protection in mice against Paracoccidioides brasiliensis infection. Vaccine 27, 606 (2009).
3. M. Wüthrich, B. Gern, C. Y. Hung, K. Ersland, N. Rocco, J. Pick- Jacobs, K. Galles, H. Filutowicz, T. Warner, M. Evans, G. Cole, and B. Klein, Vaccine-induced protection against 3 systemic mycoses endemic to North America requires Th17 cells in mice. J. Clin. Invest. 121, 554 (2011).
4. A. Bolhassani and S. Rafati, Heat-shock proteins as powerful weapons in vaccine development. Expert. Rev. 7, 1185 (2008).
5. D. Fioretti, S. Iurescia, V. M. Fazio, and M. Rinaldi, DNA vaccines: Developing new strategies against cancer. J. Biomed. Biotecnol. 2010, 174378 (2010).
6. A. M. Ribeiro, A. L. Bocca, A. C. Amaral, A. C. Souza, L. H. Faccioli, A. A. Coelho-Castelo, F. Figueiredo, C. L. Silva, and M. S. S. Felipe, HSP65 DNA as therapeutic strategy to treat experimental paracoccidioidomycosis. Vaccine 28, 1528 (2010).
7. B. H. Segal, X. Y.Wang, C. G. Dennis, R. Youn, E. A. Repasky, M. H. Manjili, and J. R. Subjeck, Heat shock proteins as vaccine adjuvants in infections and cancer. Drug. Discov. Today 11, 534 (2006).
8. C. L. Silva, V. L. Bonato, A. A. Coelho-Castelo, A. O. De Souza, S. A. Santos, K. M. Lima, L. H. Faccioli, and J. R. Lima, Immunotherapy with plasmid DNA encoding mycobacterial hsp65 in association with chemotherapy is a more rapid and efficient form of treatment for tuberculosis in mice. Gene Ther. 12, 281 (2005).
9. S. F. Zorzella-Pezavento, F. Chiuso-Minicucci, T. G. França, L. L. Ishikawa, D. R. Martins, C. L. Silva, and A. Sartori, Immunization with pVAXhsp65 decreases inflammation and modulates immune response in experimental encephalomyelitis. Neuroimmunomodulation 17, 287 (2010).
10. R. K. Gupta, E. H. Relyveld, E. B. Lindblad, B. Bizzini, S. Ben-Efraim, and C. K. Gupta, Adjuvants-a balance between toxicity and adjuvanticity. Vaccine 11, 293 (1993).
11. A. C. Amaral, A. F. Marques, J. E. Muñoz, A. L. Bocca, A. R. Simioni, A. C. Tedesco, P. C. Morais, L. R. Travassos, C. P. Taborda, and M. S. S. Felipe, Poly(lactic acid-glycolic acid) nanoparticles markedly improve immunological protection provided by peptide P10 against murine paracoccidioidomycosis. B. J. Pharmacol. 59, 1126 (2010).
12. Y. Krishnamachari, S. M. Geary, C. D. Lemke, and A. K. Salem, Nanoparticle delivery systems in cancer vaccines. Pharm. Res. 28, 215 (2011).
13. D. Mohanan, B. Slütter, M. Henriksen-Lacey, W. Jiskoot, J. A. Bouwstra, Y. Perrie, T. M. Kundig, B. Gander, and P. Johansen, Administration routes affect the quality of immune responses: A cross-sectional evaluation of particulate antigen-delivery systems. J. Control Release 147, 342 (2010).
14. Z. J. Jiang, C. Y. Liu, and L. W. Sun, Catalytic properties of silver nanoparticles supported on silica spheres. J. Phys. Chem. B 109, 1730 (2005).
15. S. Commandeur, H. M. Van Beusekom, and W. J. Van Der Giessen, Polymers, drug release, and drug-eluting stents. Xenobiotica 36, 763 (2006).
16. K. Zaks, M. Jordan, A. Guth, K. Sellins, R. Kedl, A. Izzo, C. Bosio, and S. Dow, Efficient immunization and cross-priming by vaccine adjuvants containing TLR3 or TLR9 agonists complexed to cationic liposomes. J. Immunol. 176, 7335 (2006).
17. G. Gregoriadis, DNA vaccines: A role for liposomes. Curr. Opin. Mol. Ther. 1, 39 (1999).
18. K. Yang, B. J. Whalen, R. S. Tirabassi, L. K. Selin, T. S. Levchenko, V. P. Torchilin, E. K. Kislauskis, and D. L. Guberski, A DNA vaccine prime followed by a liposome-encapsulated protein boost confers enhanced mucosal immune responses and protection. J. Immunol. 180, 6159 (2008).
19. R. Helson, W. Olszewska, M. Singh, J. Z. Megede, J. A. Melero, D. O'Hagan, and P. J. Openshaw, Polylactide-co-glycolide (PLG) microparticles modify the immune response to DNA vaccination. Vaccine 26, 753 (2008).
20. W. Ma, T. Smith, V. Bogin, Y. Zhang, C. Ozkan, M. Ozkan, M. Hayden, S. Scroter, E. Carrier, D. Messmer, V. Kumar, and B. Minev, Enhanced presentation of MHC class Ia, Ib and class II-restricted peptides encapsulated in biodegradable nanoparticles: A promising strategy for tumor immunotherapy. J. Transl. Med. 9, 34 (2011).
21. C. Clawson, C. T. Huang, D. Futalan, D. M. Seible, R. Saenz, M. Larsson, W. Ma, B. Minev, F. Zhang, M. Ozkan, C. Ozkan, S. Esener, and D. Messmer, Delivery of a peptide via poly(D,Llactic- co-glycolic) acid nanoparticles enhances its dendritic cellstimulatory capacity. Nanomedicine 5, 651 (2010).
22. Z. P. de Camargo and M. F. de Franco, Current knowledge on pathogens and immunodiagnosis of paracoccidioidomycosis. Rev. Iberoam. Micol. 17, 41 (2000).
23. V. L. G. Calich, T. A. Costa, M. Felonato, C. Arruda, S. Bernardino, F. V. Loures, L. R. Ribeiro, R. de Cássia Valente-Ferreira, and A. V. L. Pina, Innate immunity to Paracoccidioides brasiliensis infection. Mycopathologia 165, 223 (2008).
24. R. S. Rosada, L. G. de la Torre, F. G. Frantz, A. P. F. Trombone, C. R. Zárate-Bladés, D. M. Fonseca, P. R. Souza, I. T. Brandão, A. P. Masson, E. G. Soares, S. G. Ramos, L. H. Faccioli, C. L. Silva, M. H. Santana, and A. A. Coelho-Castelo, Protection against tuberculosis by a single intranasal administration of DNA-hsp65 vaccine complexed with cationic liposomes. BMC Immunol. 9, 38 (2008).
25. K. Otake, T. Shimomura, T. Goto, T. Imura, T. Furuya, S. Yoda, Y. Takebayashi, H. Sakai, and M. Abe, Preparation of liposomes using an improved supercritical reverse phase evaporation method. Langmuir 22, 2543 (2006).
26. M. Brandl and G. Gregoriadis, Entrapment of haemoglobin into liposomes by the dehydration-rehydration method: Vesicle characterization and in vivo behaviour. Biochim. Biophys. Acta 1196, 65 (1994).
27. M. F. Dias, J. Mesquita, N. Rodrigues, A. L. Filgueira, and W. De Souza, Viability of yeast form cells of Paracoccidioides brasiliensis after sonication. Med. Mycol. 42, 43 (2004).
28. L. M. Singer-Vermes, M. C. Ciavaglia, S. S. Kashino, E. Burger, and V. L. G. Calich, The source of the growth-promoting factor(s) affects the plating efficiency of Paracoccidioides brasiliensis. J. Med. Vet. Mycol. 30, 261 (1992).
29. A. L. Bocca, E. E. Hayashi, A. G. Pinheiro, A. B. Furlanetto, A. P. Campanelli, F. Q. Cunha, and F. Figueiredo, Treatment of Paracoccidioides brasiliensis-infected mice with a nitric oxide inhibitor prevents the failure of cell-mediated immune response. J. Immunol. 161, 3056 (1998).
30. L. C. Green, S. R. Tannenbaum, and P. Goldman, Nitrate synthesis in the germfree and conventional rat. Science 212, 56 (1981).
31. H. H. Schmidt, P. Wilke, B. Evers, and E. Böhme, Enzymatic formation of nitrogen oxides from L-arginine in bovine brain cytosol. Biochem. Biophys. Res. Commun. 165, 284 (1989).
32. A. F. Marques, M. B. Da Silva, M. A. Juliano, L. R. Travassos, and C. P. Taborda, Peptide immunization as an adjuvant to chemotherapy in mice challenged intratracheally with virulent yeast cells of Paracoccidioides brasiliensis. Antimicrob. Agents Chemother. 50, 2814 (2006).
33. Y. Waeckerle-Men, E. U. Allmen, B. Gander, E. Scandella, E. Schlosser, G. Schmidtke, H. P. Merkle, and M. Groettrup, Encapsulation of proteins and peptides into biodegradable poly(D,Llactide- co-glycolide) microspheres prolongs and enhances antigen presentation by human dendritic cells. Vaccine 24, 1847 (2006).
34. E. Luna, E. Postol, C. Caldas, L. A. Benvenuti, J. M. Rodrigues, K. Lima, J. Kalil, and V. Coelho, Treatment with encapsulated Hsp60 peptide (p277) prolongs skin graft survival in a murine model of minor antigen disparity. Scand. J. Immunol. 66, 62 (2007).
35. D. B. Lowrie, C. L. Silva, M. J. Colston, S. Ragno, and R. E. Tascon, Protection against tuberculosis by a plasmid DNA vaccine. Vaccine 15, 834 (1997).
36. E. A. Coelho, C. A. Tavares, K. Lima, C. L. Silva, J. M. Rodrigues, and A. P. Fernandes, Mycobacterium hsp65 DNA entrapped into TDM-loaded PLGA microspheres induces protection in mice against Leishmania (Leishmania) major infection. Parasitol. Res. 98, 568 (2006).
37. L. Romani, Immunity to fungal infection. Nat. Rev. Immunol. 11, 275 (2011).
38. K. M. Lima, S. A. Santos, V. M. Lima, A. A. Coelho-Castelo, J. M. Rodrigues, and C. L. Silva, Single dose of a vaccine based on DNA encoding mycobacterial hsp65 protein plus TDM-loaded PLGA microspheres protects mice against a virulent strain of Mycobacterium tuberculosis. Gene Ther. 10, 678 (2003).
39. A. M. Cock, L. E. Cano, D. Vélez, B. H. Aristizábal, J. Trujillo, and A. Restrepo, Fibrotic sequelae in pulmonary paracoccidioidomycosis: Histopathological aspects in BALB/c mice infected with viable and non-viable Paracoccidioides brasiliensis propagules. Rev. Inst. Med. Trop. São Paulo 42, 59 (2000).
40. L. E. Cano, S. S. Kashino, C. Arruda, D. André, C. F. Xidieh, L. M. Singer-Vermes, C. A. Vaz, E. Burger, and V. L. G. Calich, Protective role of gamma interferon in experimental pulmonary paracoccidioidomycosis. Infect Immun. 66, 800 (1998).
41. S. J. Oliveira, R. L. Mamoni, C. C. Musatti, P. M. Papaiordanou, and M. H. Blotta, Cytokines and lymphocyte proliferation in juvenile and adult forms of paracoccidioidomycosis: Comparison with infected and non-infected controls. Microbes. Infect. 4, 139 (2002).
42. M. T. Perçcoli, C. S. Kurokaw, and S. A. Calvi, Production of pro and anti-inflammatory cytokines by monocytes from patients with paracoccidioidomycosis. Microbes. Infect. 5, 413 (2003).
43. M. Arango and L. T. Yarzábal, Cell dysfunction and hyperimmunoglobulinemia E in paracoccidioidomycosis. Mycopathologia 79, 115 (1982).
44. F. V. Loures, A. Pina, M. Felonato, and V. L. G. Calich, TLR2 is a negative regulator of Th17 cells and tissue pathology in a pulmonary modelo f fungal infection. J. Immunol. 183, 1279 (2009).
45. D. A. Meire, P. C. Pereira, J. Marcondes-Machado, R. P. Mendes, B. Barraviera, J. Pellegrino, Jr, M. T. Rezkallah-Iwasso, M. T. Peraçoli, L. M. Castilho, I. Thomazini, C. L. Silva, N. T. Foss, and P. R. Curi, The use of glucan as immunostimulant in the treatment of paracoccidioidomycosis. Am. J. Trop. Med. Hyg. 55, 496 (1996).