Poly(lactic acid-glycolic acid) nanoparticles markedly improve immunological protection provided by peptide P10 against murine paracoccidioidomycosis

British Journal of Pharmacology

Volumn 159, Issue 5, 2010, Pages 1126-1132

  Amaral, André C ^a,b   Marques, Alexandre F ^c,e   Muñoz, Julián E ^c   Bocca, Anamélia L ^a   Simioni, Andreza R ^c   Tedesco, Antonio C ^c   Morais, Paulo C ^a   Travassos, Luiz R ^d   Taborda, Carlos P ^c   Felipe, Maria Sueli S ^a  

^a UNIVERSITY OF BRASILIA   (Brazil)

^b UNIVERSIDADE CATÓLICA DE BRASÍLIA   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^e UNIVERSITY OF TEXAS AT EL PASO   (United States)

Author keywords

Antifungal therapy; Biodegradable polymers; Drug delivery; Immunomodulatory peptide; Nanobiotechnology

Indexed keywords

COTRIMOXAZOLE; CYTOKINE; FREUND ADJUVANT; GAMMA INTERFERON; NANOPARTICLE; POLYGLACTIN; PROTEIN P10; SULFAMETHOXAZOLE; TRIMETHOPRIM;

ADJUVANT THERAPY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BAGG ALBINO MOUSE; CHEMOTHERAPY; CONTROLLED STUDY; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG POTENTIATION; EMULSION; IMMUNE RESPONSE; IMMUNITY; IN VIVO STUDY; LUNG; MALE; MOUSE; NONHUMAN; PARACOCCIDIOIDES BRASILIENSIS; PRIORITY JOURNAL; SOUTH AMERICAN BLASTOMYCOSIS; TREATMENT DURATION; YEAST;

ANIMALS; ANTI-INFECTIVE AGENTS; DELAYED-ACTION PREPARATIONS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; DRUG THERAPY, COMBINATION; FREUND'S ADJUVANT; GLYCOPROTEINS; IMMUNOLOGIC FACTORS; LACTIC ACID; MALE; MICE; MICE, INBRED BALB C; NANOPARTICLES; PARACOCCIDIOIDES; PARACOCCIDIOIDOMYCOSIS; PEPTIDE FRAGMENTS; POLYGLYCOLIC ACID; TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION;

EID: 77949342131     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2009.00617.x     Document Type: Article

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