Histidine supplementation improves insulin resistance through suppressed inflammation in obese women with the metabolic syndrome: A randomised controlled trial

Diabetologia

Volumn 56, Issue 5, 2013, Pages 985-994

  Feng, R N ^a   Niu, Y C ^a   Sun, X W ^a   Li, Q ^b   Zhao, C ^a   Wang, C ^a   Guo, F C ^a   Sun, C H ^a   Li, Y ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Histidine; Inflammation; Obesity; Oxidative stress

Indexed keywords

ADIPONECTIN; FATTY ACID; GLUTATHIONE PEROXIDASE; HISTIDINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MESSENGER RNA; PLACEBO; PROTEIN KINASE B; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA;

ABSENCE OF SIDE EFFECTS; ADIPOCYTE; ADULT; ALCOHOL CONSUMPTION; ARTICLE; BODY MASS; CONTROLLED STUDY; DIET SUPPLEMENTATION; DIETARY INTAKE; DOUBLE BLIND PROCEDURE; FAT MASS; FATTY ACID BLOOD LEVEL; FEMALE; HUMAN; INFLAMMATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MENOPAUSE; METABOLIC SYNDROME X; OBESITY; OXIDATIVE STRESS; PATIENT COMPLIANCE; PHYSICAL ACTIVITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; SMOKING; WAIST CIRCUMFERENCE;

ADIPOSE TISSUE, WHITE; ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BODY MASS INDEX; CELL LINE; CYTOKINES; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; DOWN-REGULATION; FEMALE; HISTIDINE; HUMANS; INSULIN RESISTANCE; METABOLIC SYNDROME X; MIDDLE AGED; OBESITY; OXIDATIVE STRESS; PILOT PROJECTS; WAIST CIRCUMFERENCE; WEIGHT LOSS;

EID: 84876499482     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-013-2839-7     Document Type: Article

References (36)

1. Reaven GM (2011) Relationships among insulin resistance, type 2 diabetes, essential hypertension, and cardiovascular disease: similarities and differences. J Clin Hypertens 13:238-243
2. Samuel VT, Shulman GI (2012) Mechanisms for insulin resistance: common threads and missing links. Cell 148:852-871
3. Urbina EM, Gao Z, Khoury PR, Martin LJ, Dolan LM (2012) Insulin resistance and arterial stiffness in healthy adolescents and young adults. Diabetologia 55:625-631
4. Bloomgarden ZT (2011) World Congress on Insulin Resistance, Diabetes, and Cardiovascular Disease: part 2. Diabetes Care 34:e126-e131
5. Henriksen EJ, Diamond-Stanic MK, Marchionne EM (2011) Oxidative stress and the etiology of insulin resistance and type 2 diabetes. Free Radic Biol Med 51:993-999
6. Schipper HS, Nuboer R, Prop S, et al.(2012) Systemic inflammation in childhood obesity: circulating inflammatory mediators and activated CD14++ monocytes. Diabetologia 55:2800-2810
7. Selvaraju V, Joshi M, Suresh S, Sanchez JA, Maulik N, Maulik G (2012) Diabetes, oxidative stress, molecular mechanism, and cardiovascular disease - an overview. Toxicol Mech Methods 22:330-335
8. Watanabe M, Suliman ME, Qureshi AR, et al.(2008) Consequences of low plasma histidine in chronic kidney disease patients: associations with inflammation, oxidative stress, and mortality. Am J Clin Nutr 87:1860-1866
9. Niu YC, Feng RN, Hou Y, et al.(2012) Histidine and arginine are associated with inflammation and oxidative stress in obese women. Br J Nutr 108:57-61
10. Mihalik SJ, Michaliszyn SF, de las Heras J, et al.(2012) Metabolomic profiling of fatty acid and amino acid metabolism in youth with obesity and type 2 diabetes: evidence for enhanced mitochondrial oxidation. Diabetes Care 35:605-611
11. Zhou BF (2002) Predictive values of body mass index and waist circumference for risk factors of certain related diseases in Chinese adults - study on optimal cut-off points of body mass index and waist circumference in Chinese adults. Biomed Environ Sci 15:83-96
12. Alberti KG, Zimmet P, Shaw J (2005) The metabolic syndrome - a new worldwide definition. Lancet 366:1059-1062
13. Rabbani GH, Sack DA, Ahmed S, et al.(2005) Antidiarrheal effects of l-histidine-supplemented rice-based oral rehydration solution in the treatment of male adults with severe cholera in Bangladesh: a double-blind, randomized trial. J Infect Dis 191:1507-1514
14. Okubo H, Sasaki S (2005) Histidine intake may negatively correlate with energy intake in human: a cross-sectional study in Japanese female students aged 18 years. J Nutr Sci Vitaminol (Tokyo) 51:329-334
15. Zlotkin SH (1989) Nutrient interactions with total parenteral nutrition: effect of histidine and cysteine intake on urinary zinc excretion. J Pediatr 114:859-864
16. Schechter PJ, Prakash NJ (1979) Failure of oral l-histidine to influence appetite or affect zinc metabolism in man: a double-blind study. Am J Clin Nutr 32:1011-1014
17. Li Y, Wang C, Zhu K, Feng RN, Sun CH (2010) Effects of multivitamin and mineral supplementation on adiposity, energy expenditure and lipid profiles in obese Chinese women. Int J Obes 34:1070-1077
18. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412-419
19. He Y, Zhang H, Teng J, Huang L, Li Y, Sun C (2011) Involvement of calcium-sensing receptor in inhibition of lipolysis through intracellular cAMP and calcium pathways in human adipocytes. Biochem Biophys Res Commun 404:393-399
20. Fears CYGJ, Stewart JE Jr, Annis DS, Mosher DF, Bornstein P, Gladson CL (2005) Low-density lipoprotein receptor-related protein contributes to the antiangiogenic activity of thrombospondin-2 in a murine glioma model. Cancer Res 65:9338-9346
21. Choi S, Kim JH, Roh EJ, Ko MJ, Jung JE, Kim HJ (2006) Nuclear factor-kappaB activated by capacitative Ca2+ entry enhances muscarinic receptor-mediated soluble amyloid precursor protein (sAPPalpha) release in SH-SY5Y cells. J Biol Chem 281:12722-12728
22. Geliebter AA, Hashim SA, Van Itallie TB (1981) Oral l-histidine fails to reduce taste and smell acuity but induces anorexia and urinary zinc excretion. Am J Clin Nutr 34:119-120
23. Babizhayev MA, Seguin MC, Gueyne J, Evstigneeva RP, Ageyeva EA, Zheltukhina GA (1994) l-carnosine (beta-alanyl-l-histidine) and carcinine (beta-alanylhistamine) act as natural antioxidants with hydroxyl-radical- scavenging and lipid-peroxidase activities. Biochem J 304(Pt 2):509-516
24. Lee JW, Miyawaki H, Bobst EV, Hester JD, Ashraf M, Bobst AM (1999) Improved functional recovery of ischemic rat hearts due to singlet oxygen scavengers histidine and carnosine. J Mol Cell Cardiol 31:113-121
25. Yan SL, Wu ST, Yin MC, Chen HT, Chen HC (2009) Protective effects from carnosine and histidine on acetaminophen-induced liver injury. J Food Sci 74:H259-H265
26. Cuzzocrea S, Genovese T, Failla M, et al.(2007) Protective effect of orally administered carnosine on bleomycin-induced lung injury. Am J Physiol Lung Cell Mol Physiol 292:L1095-L1104
27. Lee YT, Hsu CC, Lin MH, Liu KS, Yin MC (2005) Histidine and carnosine delay diabetic deterioration in mice and protect human low density lipoprotein against oxidation and glycation. Eur J Pharmacol 513:145-150
28. Kulebyakin K, Karpova L, Lakonsteva E, Krasavin M, Boldyrev A (2012) Carnosine protects neurons against oxidative stress and modulates the time profile of MAPK cascade signaling. Amino acids 43:91-96
29. Farshid AA, Tamaddonfard E, Yahyaee F (2010) Effects of histidine and N-acetylcysteine on diclofenac-induced anti-inflammatory response in acute inflammation in rats. Indian J Exp Biol 48:1136-1142
30. Son DO, Satsu H, Shimizu M (2005) Histidine inhibits oxidative stress- and TNF-alpha-induced interleukin-8 secretion in intestinal epithelial cells. FEBS Lett 579:4671-4677
31. Hasegawa S, Ichiyama T, Sonaka I, et al.(2012) Cysteine, histidine and glycine exhibit anti-inflammatory effects in human coronary arterial endothelial cells. Clin Exp Immunol 167:269-274
32. Tilg H, Moschen AR (2008) Role of adiponectin and PBEF/visfatin as regulators of inflammation: involvement in obesity-associated diseases. Clin Sci (Lond) 114:275-288
33. Bernstein EL, Koutkia P, Ljungquist K, Breu J, Canavan B, Grinspoon S (2004) Acute regulation of adiponectin by free fatty acids. Metabolism 53:790-793
34. Mong MC, Chao CY, Yin MC (2011) Histidine and carnosine alleviated hepatic steatosis in mice consumed high saturated fat diet. Eur J Pharmacol 653:82-88
35. Wu G (2009) Amino acids: metabolism, functions, and nutrition. Amino Acids 37:1-17
36. Kasaoka S, Kawahara Y, Inoue S, et al.(2005) Gender effects in dietary histidine-induced anorexia. Nutrition 21:855-858