Multiple e-pharmacophore modeling combined with high-throughput virtual screening and docking to identify potential inhibitors of β- secretase(BACE1)

Molecular Informatics

Volumn 32, Issue 4, 2013, Pages 385-398

  Palakurti, Ravichand ^a   Sriram, Dharmarajan ^a   Yogeeswari, Perumal ^a   Vadrevu, Ramakrishna ^a  

^a BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

Alzheimer's disease; Blood brain barrier; Docking; e Pharmacophore; Virtual screening; Secretase

Indexed keywords

BLOOD; CRYSTAL STRUCTURE; DIAGNOSIS; GLYCOPROTEINS; PHARMACODYNAMICS; THROUGHPUT;

ALZHEIMERS DISEASE; BLOOD-BRAIN BARRIER; CRYSTALS STRUCTURES; DOCKING; E-PHARMACOPHORE; PHARMACOPHORE MODELS; PHARMACOPHORES; SECRETASES; VIRTUAL SCREENING; Β-SECRETASE;

NEURODEGENERATIVE DISEASES;

BETA SECRETASE INHIBITOR;

ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; DRUG IDENTIFICATION; FLUORESCENCE; HIGH THROUGHPUT SCREENING; MOLECULAR DOCKING; PHARMACOPHORE; PREDICTION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 84876489208     PISSN: 18681743     EISSN: 18681751     Source Type: Journal    
DOI: 10.1002/minf.201200169     Document Type: Article

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