Macular pigment optical density in young adults of South Asian origin

Investigative Ophthalmology and Visual Science

Volumn 54, Issue 4, 2013, Pages 2711-2719

  Howells, Olivia ^a   Eperjesi, Frank ^a   Bartlett, Hannah ^a  

^a ASTON UNIVERSITY   (United Kingdom)

Author keywords

Age related macular degeneration; Heterochromatic flicker photometry; Macular pigment; Macular pigment optical density

Indexed keywords

VISUAL PIGMENT;

ADULT; ARTICLE; ASIAN; DIET; ENVIRONMENTAL FACTOR; ETHNIC DIFFERENCE; EYE COLOR; FEMALE; HUMAN; LIFESTYLE; MALE; NORMAL HUMAN; OPTICAL DENSITY; PERSONALITY; PRIORITY JOURNAL; QUESTIONNAIRE; RETINA MACULA AGE RELATED DEGENERATION; RISK FACTOR; SPECTROPHOTOMETRY; VISUAL ACUITY; VISUAL STIMULATION;

ADOLESCENT; ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; DENSITOMETRY; ENVIRONMENT; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FOOD HABITS; HUMANS; LIFE STYLE; LUTEIN; MACULA LUTEA; MACULAR DEGENERATION; MALE; PHOTOMETRY; QUESTIONNAIRES; RETINAL PIGMENTS; XANTHOPHYLLS; YOUNG ADULT;

EID: 84876474503     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.12-10957     Document Type: Article

References (97)

1. Sommer A, Tielsch JM, Katz J, et al. Racial differences in the cause-specific prevalence of blindness in east Baltimore. N Engl J Med. 1991;325:1412-1417.
2. Rahmani B, Tielsch JM, Katz J, et al. The cause-specific prevalence of visual impairment in an urban population. The Baltimore Eye Survey. Ophthalmology. 1996;103:1721-1726.
3. Klein R, Clegg L, Cooper LS, et al. Prevalence of age-related maculopathy in the Atherosclerosis Risk in Communities Study. Arch Ophthalmol. 1999;117:1203-1210.
4. Frank RN, Puklin JE, Stock C, Canter LA. Race, iris color, and age-related macular degeneration. Trans Am Ophthalmol Soc. 2000;98:109-117.
5. Muñoz B, West SK, Rubin GS, et al. Causes of blindness and visual impairment in a population of older Americans: the Salisbury Eye Evaluation Study. Arch Ophthalmol. 2000;118: 819-825.
6. Klein R, Klein BE, Marino EK, et al. Early age-related maculopathy in the cardiovascular health study. Ophthalmology. 2003;110:25-33.
7. Congdon N, O'Colmain B, Klaver CC, et al. Causes and prevalence of visual impairment among adults in the United States. Arch Ophthalmol. 2004;122:477-485.
8. Friedman DS, O'Colmain BJ, Muñoz B, et al. Prevalence of age-related macular degeneration in the United States. Arch phthalmol. 2004;122:564-572.
9. Friedman DS, West SK, Munoz B, et al. Racial variations in causes of vision loss in nursing homes: the Salisbury Eye Evaluation in Nursing Home Groups (SEEING) Study. Arch Ophthalmol. 2004;122:1019-1024.
10. Leske MC, Wu SY, Hennis A, et al. Nine-year incidence of age-related macular degeneration in the Barbados Eye Studies. Ophthalmology. 2006;113:29-35.
11. Duan Y, Mo J, Klein R, et al. Age-related macular degeneration is associated with incident myocardial infarction among elderly Americans. Ophthalmology. 2007;114:732-737.
12. Klein R, Chou CF, Klein BE, Zhang X, Meuer SM, Saaddine JB. Prevalence of age-related macular degeneration in the US population. Arch Ophthalmol. 2011;129:75-80.
13. Vanderbeek BL, Zacks DN, Talwar N, Nan B, Musch DC, Stein JD. Racial differences in age-related macular degeneration rates in the United States: a longitudinal analysis of a managed care network. Am J Ophthalmol. 2011;152:273-282.
14. Chang TS, Hay D, Courtright P. Age-related macular degeneration in Chinese-Canadians. Can J Ophthalmol. 1999;34:266-271.
15. Oshima Y, Ishibashi T, Murata T, Tahara Y, Kiyohara Y, Kubota T. Prevalence of age related maculopathy in a representative Japanese population: the Hisayama study. Br J Ophthalmol. 2001;85:1153-1157.
16. Rodriguez J, Sanchez R, Munoz B, et al. Causes of blindness and visual impairment in a population-based sample of U.S. Hispanics. Ophthalmology. 2002;109:737-743.
17. Iwase A, Araie M, Tomidokoro A, Yamamoto T, Shimizu H, Kitazawa Y. Prevalence and causes of low vision and blindness in a Japanese adult population: the Tajimi Study. Ophthalmology. 2006;113:1354-1362.
18. Li Y, Xu L, Jonas JB, Yang H, Ma Y, Li J. Prevalence of age-related maculopathy in the adult population in China: the Beijing Eye Study. Am J Ophthalmol. 2006;142:788-793.
19. Sivaprasad S, Membrey WL, Sivagnanavel V, et al. Second eye of patients with unilateral neovascular age-related macular degeneration: Caucasians vs Chinese. Eye (Lond). 2006;20: 923-926.
20. Yasuda M, Kiyohara Y, Hata Y, et al. Nine-year incidence and risk factors for age-related macular degeneration in a defined Japanese population the Hisayama study. Ophthalmology. 2009;116:2135-2140.
21. Varma R, Foong AW, Lai MY, Choudhury F, Klein R, Azen SP. Four-year incidence and progression of age-related macular degeneration: the Los Angeles Latino Eye Study. Am J Ophthalmol. 2010;149:741-751.
22. Krishnaiah S, Das T, Nirmalan PK, et al. Risk factors for agerelated macular degeneration: findings from the Andhra Pradesh Eye Disease Study in South India. Invest Ophthalmol Vis Sci. 2005;46:4442-4449.
23. Gupta SK, Murthy GV, Morrison N, et al. Prevalence of early and late age-related macular degeneration in a rural population in northern India: the INDEYE feasibility study. Invest Ophthalmol Vis Sci. 2007;48:1007-1011.
24. Krishnaiah S, Das TP, Kovai V, Rao GN. Associated factors for age-related maculopathy in the adult population in southern India: the Andhra Pradesh Eye Disease Study. Br J Ophthalmol. 2009;93:1146-1150.
25. Cheung CMG, Tai ES, Kawasaki R, et al. Prevalence of and risk factors for age-related macular degeneration in a multiethnic Asian cohort. Arch Ophthalmol. 2012;130:480-486.
26. Kawasaki R, Yasuda M, Song SJ, et al. The prevalence of age-related macular degeneration in Asians: a systematic review and meta-analysis. Ophthalmology. 2010;117:921-927.
27. Bone RA, Landrum JT, Hime GW, Cains A, Zamor J. Stereochemistry of the human macular carotenoids. Invest Ophthalmol Vis Sci. 1993;34:2033-2040.
28. Malinow MR, Feeney-Burns L, Peterson LH, Klein ML, Neuringer M. Diet-related macular anomalies in monkeys. Invest Ophthalmol Vis Sci. 1980;19:857-863.
29. Neuringer M, Sandstrom MM, Johnson EJ, Snodderly DM. Nutritional manipulation of primate retinas, I: effects of lutein or zeaxanthin supplements on serum and macular pigment in xanthophyll-free rhesus monkeys. Invest Ophthalmol Vis Sci. 2004;45:3234-3243.
30. Wyszecki G, Stiles WS. The eye. Color Science: Concepts and Methods, Quantitative Data and Formulae. New York: Wiley-Interscience; 1982:112-114.
31. Snodderly DM, Brown PK, Delori FC, Auran JD. The macular pigment. I. Absorbance spectra, localization, and discrimination from other yellow pigments in primate retinas. Invest Ophthalmol Vis Sci. 1984;25:660-673.
32. Handelman GJ, Snodderly DM, Krinsky NI, Russett MD, Adler AJ. Biological control of primate macular pigment biochemical and densitometric studies. Invest Ophthalmol Vis Sci. 1991;32:257-267.
33. Bone RA, Landrum JT, Cains A. Optical density spectra of the macular pigment in vivo and in vitro. Vision Res. 1992;32: 105-110.
34. Hammond BR, Caruso-Avery M. Macular pigment optical density in a southwestern sample. Invest Ophthalmol Vis Sci. 2000;41:1492-1497.
35. Landrum JT, Bone RA. Lutein, zeaxanthin, and the macular pigment. Arch Biochem Biophys. 2001;385:28-40.
36. Chucair AJ, Rotstein NP, SanGiovanni JP, During A, Chew EY, Politi LE. Lutein and zeaxanthin protect photoreceptors from apoptosis induced by oxidative stress: relation with docosahexaenoic acid. Invest Ophthalmol Vis Sci. 2007;48:5168-5177.
37. Khachik F, Bernstein PS, Garland DL. Identification of lutein and zeaxanthin oxidation products in human and monkey retinas. Invest Ophthalmol Vis Sci. 1997;38:1802-1811.
38. Beatty S, Koh H-H, Henson D, Boulton M. The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv Ophthalmol. 2000;45:115-134.
39. Algvere PV, Marshall J, Seregard S. Age-related maculopathy and the impact of blue light hazard. Acta Ophthalmol Scand. 2006;84:4-15.
40. Beatty S, Murray IJ, Henson DB, Carden D, Koh HH, Boulton ME. Macular pigment and risk for age-related macular degeneration in subjects from a Northern European population. Invest Ophthalmol Vis Sci. 2001;42:439-446.
41. Bone RA, Landrum JT, Mayne ST, Gomez CM, Tibor SE, Twaroska EE. Macular pigment in donor eyes with and without AMD: A case-control study. Invest Ophthalmol Vis Sci. 2001;42:235-240.
42. Richer S, Stiles W, Statkute L, et al. Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supple-mentation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (Lutein Antioxidant Supplementation Trial). Optometry. 2004;75:216-230.
43. Nolan JM, Stack J, O'Donovan O, Loane E, Beatty S. Risk factors for age-related maculopathy are associated with a relative lack of macular pigment. Exp Eye Res. 2007;84:61-74.
44. Wolf-Schnurrbusch UEK, Roosli N, Weyermann E, Heldner MR, Hohne K, Wolf S. Ethnic differences in macular pigment density and distribution. Invest Ophthalmol Vis Sci. 2007;48: 3783-3787.
45. Iannaccone A, Mura M, Gallaher KT, et al. Macular pigment optical density in the elderly: findings in a large biracial midsouth population sample. Invest Ophthalmol Vis Sci. 2007;48:1458-1465.
46. Nolan JM, Stringham JM, Beatty S, Snodderly DM. Spatial profile of macular pigment and its relationship to foveal architecture. Invest Ophthalmol Vis Sci. 2008;49:2134-2142.
47. Hammond BR, Fuld K, Snodderly DM. Iris color and macular pigment optical density. Exp Eye Res. 1996;62:715-720.
48. Bernstein PS, Zhao DY, Wintch SW, Ermakov IV, McClane RW, Gellermann W. Resonance Raman measurement of macular carotenoids in normal subjects and in age-related macular degeneration patients. Ophthalmology. 2002;109:1780-1787.
49. Tang CY, Yip HS, Poon MY, Yau WL, Yap MKH. Macular pigment optical density in young Chinese adults. Ophthalmic Physiol Opt. 2004;24:586-593.
50. Lam RF, Rao SK, Fan DSP, Lau FTC, Lam DSC. Macular pigment optical density in a Chinese sample. Curr Eye Res. 2005;30: 729-735.
51. Obana A, Hiramitsu T, Gohto Y, et al. Macular carotenoid levels of normal subjects and age-related maculopathy patients in a Japanese population. Ophthalmology. 2008;115:147-157.
52. Sasamoto Y, Gomi F, Sawa M, Sakaguchi H, Tsujikawa M, Hamasaki T. Macular pigment optical density in central serous chorioretinopathy. Invest Ophthalmol Vis Sci. 2010;51:5219-5225.
53. Raman R, Rajan R, Biswas S, Vaitheeswaran K, Sharma T. Macular pigment optical density in a South Indian population. Invest Ophthalmol Vis Sci. 2011;52:7910-7916.
54. van der Veen RLP, Berendschot TTJM, Hendrikse F, Carden D, Makridaki M, Murray IJ. A new desktop instrument for measuring macular pigment optical density based on a novel technique for setting flicker thresholds. Ophthalmic Physiol Opt. 2009;29:127-137.
55. Howells O, Eperjesi F, Bartlett H. Improving the repeatability of heterochromatic flicker photometry for measurement of macular pigment optical density. Graefes Arch Clin Exp Ophthalmol. 2013;251:871-880.
56. Mellerio J, Ahmadi-Lari S, van Kuijk F, Pauleikhoff D, Bird A, Marshall J. A portable instrument for measuring macular pigment with central fixation. Curr Eye Res. 2002;25:37-47.
57. Burke JD, Curran-Celentano J, Wenzel AJ. Diet and serum carotenoid concentrations affect macular pigment optical density in adults 45 years and older. J Nutr. 2005;135:1208-1214.
58. Nolan JM, Kenny R, O'Regan C, et al. Macular pigment optical density in an ageing Irish population: The Irish Longitudinal Study on Ageing. Ophthalmic Res. 2010;44:131-139.
59. Makridaki M, Carden D, Murray IJ. Macular pigment measurement in clinics: controlling the effect of the ageing media. Ophthalmic Physiol Opt. 2009;29:338-344.
60. van der Veen RLP, Berendschot TTJM, Makridaki M, Hendrikse F, Carden D, Murray IJ. Correspondence between retinal reflectometry and a flicker-based technique in the measurement of macular pigment spatial profiles. J Biomed Opt. 2009; 14:064046.
61. Bartlett H, Stainer L, Singh S, Eperjesi F, Howells O. Clinical evaluation of the MPS 9000 Macular Pigment Screener. Br J Ophthalmol. 2010;94:753-756.
62. Berrow EJ, Bartlett HE, Eperjesi F. Do lutein, zeaxanthin and macular pigment optical density differ with age or age-related maculopathy? e-SPEN. 2011;6:e197-e201.
63. de Kinkelder R, van der Veen RLP, Verbaak FD, Faber DJ, van Leeuwen TG, Berendschot TTJM. Macular pigment optical density measurements: evaluation of a device using hetero-chromatic flicker photometry. Eye (Lond). 2011;25:105-112.
64. Richer, SP, Stiles W, Graham-Hoffman K, et al. Randomized, double-blind, placebo-controlled study of zeaxanthin and visual function in patients with atrophic age-related macular degeneration. The Zeaxanthin and Visual Function Study (ZVF) FDA IND #78, 973. Optometry. 2011;82:667-680.
65. Qin L, Bartlett H, Griffiths HR, Eperjesi F, Armstrong RA, Gherghel D. Macular pigment optical density is related to blood glutathione levels in healthy individuals. Invest Ophthalmol Vis Sci. 2011;52:5029-5033.
66. Tsika C, Tsilimbaris MK, Makridaki M, Kontadakis G, Plainis S, Moschandreas J. Assessment of macular pigment optical density (MPOD) in patients with unilateral wet age-related macular degeneration (AMD). Acta Ophthalmol. 2011;89: e573-e578.
67. Hammond BR, Curran-Celentano J, Judd S, et al. Sex differences in macular pigment optical density: relation to plasma carotenoid concentrations and dietary patterns. Vision Res. 1996;36:2001-2012.
68. Wooten BR, Hammond BR, Land RI, Snodderly DM. A practical method for measuring macular pigment optical density. Invest Ophthalmol Vis Sci. 1999;40:2481-2489.
69. Berendschot TTJM, Broekmans WMR, Klöpping-Ketelaars IAA, Kardinaal AFM, van Poppel G, van Norren D. Lens aging in relation to nutritional determinants and possible risk factors for age-related cataract. Arch Ophthalmol. 2002;120:1732-1737.
70. Broekmans WMR, Berendschot TTJM, Klöpping-Ketelaars IAA, et al. Macular pigment density in relation to serum and adipose tissue concentrations of lutein and serum concentrations of zeaxanthin. Am J Clin Nutr. 2002;76:595-603.
71. Lam RF, Rao SK, Fan DSP, Lau FTC, Lam DSC. Macular pigment optical density in a Chinese sample. Curr Eye Res. 2005;30: 729-735.
72. Yu J, Johnson EJ, Shang F, et al. Measurement of macular pigment optical density in a healthy Chinese population sample. Invest Ophthalmol Vis Sci. 2012;53:2106-2111.
73. Ham WT, Mueller HA, Sliney DH. Retinal sensitivity to damage from short wavelength light. Nature. 1976;260:153-155.
74. Ham WT, Ruffolo JJ, Mueller HA, Clarke AM, Moon ME. Histologic analysis of photochemical lesions produced in rhesus retina by short-wave-length light. Invest Ophthalmol Vis Sci. 1978;17:1029-1035.
75. Ham WT, Ruffolo JJ, Mueller HA, Guerry D. The nature of retinal radiation damage: dependence on wavelength, power level and exposure time. Vision Res. 1980;20:1105-1011.
76. Ham WT, Mueller HA, Ruffolo JJ, Guerry D, Guerry RK. Action spectrum for retinal injury from near-ultraviolet radiation in the aphakic monkey. Am J Ophthalmol. 1982;93:299-306.
77. Taylor HR, West S, Muñoz B, Rosenthal FS, Bressler SB, Bressler NM. The long-term effects of visible light on the eye. Arch Ophthalmol. 1992;110:99-104.
78. Tomany SC, Cruickshanks KJ, Klein R, Klein BEK, Knudtson MD. Sunlight and the 10-year incidence of age-related maculopathy-The Beaver Dam Eye Study. Arch Ophthalmol. 2004;122:750-757.
79. Hirakawa M, Tanaka M, Tanaka Y, et al. Age-related maculopathy and sunlight exposure evaluated by objective measurement. Br J Ophthalmol. 2008;92:630-634.
80. Wenzel AJ, Fuld K, Stringham JM, Curran-Celentano J. Macular pigment optical density and photophobia light threshold. Vision Res. 2006;46:4615-4622.
81. Stringham JM, Hammond BR. The glare hypothesis of macular pigment function. Optom Vis Sci. 2007;84:859-864.
82. Stringham JM, Hammond BR. Macular pigment and visual performance under glare conditions. Optom Vis Sci. 2008;85: 82-88.
83. Stringham JM, Garcia PV, Smith PA, McLin LN, Foutch BK. Macular pigment and visual performance in glare: benefits for photostress recovery, disability glare, and visual discomfort. Invest Ophthalmol Vis Sci. 2011;52:7406-7415.
84. Hu DN, Simon JD, Sarna T. Role of ocular melanin in ophthalmic physiology and pathology. Photochem Photobiol. 2008;84:639-644.
85. Hyman LG, Lilienfeld AM, Ferris FL, Fine SL. Senile macular degeneration: a case-control study. Am J Epidemiol. 1983;118: 213-227.
86. Weiter JJ, Delori FC, Wing GL, Fitch KA. Relationship of senile macular degeneration to ocular pigmentation. Am J Ophthalmol. 1985;99:185-187.
87. Sandberg MA, Gaudio AR, Miller S, Weiner A. Iris pigmentation and extent of disease in patients with neovascular age-related macular degeneration. Invest Ophthalmol Vis Sci. 1994;35: 2734-2740.
88. Mitchell P, Smith W, Wang JJ. Iris color, skin sun sensitivity, and age-related maculopathy. The Blue Mountains Eye Study. Ophthalmology. 1998;105:1359-1363.
89. Nicolas CM, Robman LD, Tikellis G, et al. Iris colour, ethnic origin and progression of age-related macular degeneration. Clin Experiment Ophthalmol. 2003;31:465-469.
90. Ciulla TA, Curran-Celantano J, Cooper DA, et al. Macular pigment optical density in a midwestern sample. Ophthalmology. 2001;108:730-737.
91. Kirby ML, Beatty S, Loane E, et al. A central dip in the macular pigment spatial profile is associated with age and smoking. Invest Ophthalmol Vis Sci. 2010;51:6722-6728.
92. Sandberg MA, Johnson EJ, Berson EL. The relationship of macular pigment optical density to serum lutein in retinitis pigmentosa. Invest Ophthalmol Vis Sci. 2010;51:1086-1091.
93. Hammond BR, Fuld K, Curran-Celentano J. Macular pigment density in monozygotic twins. Invest Ophthalmol Vis Sci. 1995;36:2531-2541.
94. Liew SHM, Gilbert CE, Spector TD, et al. Heritability of macular pigment: a twin study. Invest Ophthalmol Vis Sci. 2005;46:4430-4436.
95. Wenzel AJ, Sheehan JP, Burke JD, Lefsrud MG, Curran-Celentano J. Dietary intake and serum concentrations of lutein and zeaxanthin, but not macular pigment optical density, are related in spouses. Nutr Res. 2007;27:462-469.
96. Loane E, McKay GJ, Nolan JM, Beatty S. Apolipoprotein E genotype is associated with macular pigment optical density. Invest Ophthalmol Vis Sci. 2010;51:2636-2643.
97. Wolffsohn J, Eperjesi F, Bartlett H, et al. Does blocking ultraviolet light with contact lenses benefit eye health? Paper presented at: British Contact Lens Association (BCLA) Conference; May 24-27, 2012; Birmingham, UK.