Gene expression levels of S100 protein family in blood cells are associated with insulin resistance and inflammation (Peripheral blood S100 mRNAs and metabolic syndrome)

Biochemical and Biophysical Research Communications

Volumn 433, Issue 4, 2013, Pages 450-455

  Yamaoka, Masaya ^a   Maeda, Norikazu ^a   Nakamura, Seiji ^b   Mori, Takuya ^a   Inoue, Kana ^a   Matsuda, Keisuke ^a   Sekimoto, Ryohei ^a   Kashine, Susumu ^a   Nakagawa, Yasuhiko ^a   Tsushima, Yu ^a   Fujishima, Yuya ^a   Komura, Noriyuki ^a   Hirata, Ayumu ^a   Nishizawa, Hitoshi ^a   Matsuzawa, Yuji ^c   Matsubara, Ken ichi ^b   Funahashi, Tohru ^a   Shimomura, Iichiro ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b DNA CHIP RESEARCH INC   (Japan)

^c SUMITOMO HOSPITAL   (Japan)

Author keywords

Inflammation; Insulin resistance; Metabolic syndrome; Obesity; S100 family

Indexed keywords

ADIPONECTIN; C REACTIVE PROTEIN; CALGRANULIN A; CALGRANULIN B; MESSENGER RNA; PROTEIN S 100; PROTEIN S 100 A12; UNCLASSIFIED DRUG;

ARTICLE; BODY MASS; DISEASE ASSOCIATION; DNA MICROARRAY; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC ANALYSIS; HUMAN; INFLAMMATION; INSULIN RESISTANCE; INTRAABDOMINAL FAT; MAJOR CLINICAL STUDY; METABOLIC SYNDROME X; MICROARRAY ANALYSIS; OBESITY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADIPONECTIN; ADIPOSITY; ASIAN CONTINENTAL ANCESTRY GROUP; BLOOD CELLS; BODY MASS INDEX; C-REACTIVE PROTEIN; CALGRANULIN A; CALGRANULIN B; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION STUDIES; GENOME, HUMAN; HUMANS; INFLAMMATION; INSULIN RESISTANCE; INTRA-ABDOMINAL FAT; METABOLIC SYNDROME X; OBESITY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REGRESSION ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; S100 PROTEINS; TRANSCRIPTOME;

EID: 84876464671     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.02.096     Document Type: Article

References (24)

1. Matsuzawa Y. Therapy insight: adipocytokines in metabolic syndrome and related cardiovascular disease. Nat. Clin. Pract. Cardiovasc. Med. 2006, 3:35-42.
2. Osborn O., Olefsky J.M. The cellular and signaling networks linking the immune system and metabolism in disease. Nat. Med. 2012, 18:363-374.
3. Gregor M.F., Hotamisligil G.S. Inflammatory mechanisms in obesity. Annu. Rev. Immunol. 2011, 29:415-445.
4. Flier J.S. Obesity wars: molecular progress confronts an expanding epidemic. Cell 2004, 116:337-350.
5. Yamaoka M., Maeda N., Nakamura S., Kashine S., Nakagawa Y., Hiuge-Shimizu A., Okita K., Imagawa A., Matsuzawa Y., Matsubara K., Funahashi T., Shimomura I. A pilot investigation of visceral fat adiposity and gene expression profile in peripheral blood cells. PLoS ONE 2012, 7:e47377.
6. Ryo M., Maeda K., Onda T., Katashima M., Okumiya A., Nishida M., Yamaguchi T., Funahashi T., Matsuzawa Y., Nakamura T., Shimomura I. A new simple method for the measurement of visceral fat accumulation by bioelectrical impedance. Diabetes Care 2005, 28:451-453.
7. Nakatsuji H., Kishida K., Funahashi T., Noguchi M., Ogawa T., Okauchi Y., Nishizawa H., Nakamura T., Matsuzawa Y., Shimomura I. One -year reductions in body weight and blood pressure, but not in visceral fat accumulation and adiponectin, improve urinary albumin-to-creatinine ratio in middle-aged Japanese men. Diabetes Care 2010, 33:e110-e111.
8. Hiuge-Shimizu A., Maeda N., Hirata A., Nakatsuji H., Nakamura K., Okuno A., Kihara S., Funahashi T., Shimomura I. Dynamic changes of adiponectin and S100A8 levels by the selective peroxisome proliferator-activated receptor-gamma agonist rivoglitazone. Arterioscler. Thromb. Vasc. Biol. 2011, 31:792-799.
9. Sekimoto R, Kishida K, Nakatsuji H, Nakagawa T, Funahashi T, Shimomura I High circulating levels of S100A8/A9 complex (calprotectin) in male Japanese with abdominal adiposity and dysregulated expression of S100A8 and S100A9 in adipose tissues of obese mice. Biochem. Biophys. Res. Commun. 2012, 419:782-789.
10. Hirata A., Kishida K., Nakatsuji H., Hiuge-Shimizu A., Funahashi T., Shimomura I. High serum S100A8/A9 levels and high cardiovascular complication rate in type 2 diabetic with ultrasonographic low carotid plaque density. Diabetes Res. Clin. Pract. 2012, 97:82-90.
11. Healy A.M., Pickard M.D., Pradhan A.D., Wang Y., Chen Z., Croce K., Sakuma M., Shi C., Zago A.C., Garasic J., Damokosh A.I., Dowie T.L., Poisson L., Lillie J., Libby P., Ridker P.M., Simon D.I. Platelet expression profiling and clinical validation of myeloid-related protein-14 as a novel determinant of cardiovascular events. Circulation 2006, 113:2278-2284.
12. Morrow D.A., Wang Y., Croce K., Sakuma M., Sabatine M.S., Gao H., Pradhan A.D., Healy A.M., Buros J., McCabe C.H., Libby P., Cannon C.P., Braunwald E., Simon D.I. Myeloid-related protein 8/14 and the risk of cardiovascular death or myocardial infarction after an acute coronary syndrome in the Pravastatin or Atorvastatin evaluation and infection therapy: thrombolysis in myocardial infarction (PROVE IT-TIMI 22) trial. Am. Heart J. 2008, 155:49-55.
13. Croce K. S100A8/A9 complex: more than just a biomarker of cardiovascular risk?. Circ. J. 2010, 74:626-627.
14. Mortensen O.H., Nielsen A.R., Erikstrup C., Plomgaard P., Fischer C.P., Krogh-Madsen R., Lindegaard B., Petersen A.M., Taudorf S., Pedersen B.K. Calprotectin-a novel marker of obesity. PLoS ONE 2009, 4:e7419.
15. Catalán V., Gómez-Ambrosi J., Rodríguez A., Ramírez B., Rotellar F., Valentí V., Silva C., Gil M.J., Fernández-Real J.M., Salvador J., Frühbeck G. Increased levels of calprotectin in obesity are related to macrophage content: impact on inflammation and effect of weight loss. Mol. Med. 2011, 17:1157-1167.
16. Lim S.Y., Raftery M.J., Goyette J., Hsu K., Geczy C.L. Oxidative modifications of S100 proteins: functional regulation by redox. J. Leukoc. Biol. 2009, 86:577-587.
17. Vogl T., Tenbrock K., Ludwig S., Leukert N., Ehrhardt C., van Zoelen M.A., Nacken W., Foell D., van der Poll T., Sorg C., Roth J. Mrp8 and Mrp14 are endogenous activators of toll-like receptor 4, promoting lethal, endotoxin-induced shock. Nat. Med. 2007, 13:1042-1049.
18. Leclerc E., Fritz G., Vetter S.W., Heizmann C.W. Binding of S100 proteins to RAGE: an update. Biochim. Biophys. Acta 2009, 1793:993-1007.
19. Kosaki A., Hasegawa T., Kimura T., Iida K., Hitomi J., Matsubara H., Mori Y., Okigaki M., Toyoda N., Masaki H., Inoue-Shibata M., Nishikawa M., Iwasaka T. Increased plasma S100A12 (EN-RAGE) levels in patients with type 2 diabetes. J. Clin. Endocrinol. Metab. 2004, 89:5423-5428.
20. Basta G., Sironi A.M., Lazzerini G., Del Turco S., Buzzigoli E., Casolaro A., Natali A., Ferrannini E., Gastaldelli A. Circulating soluble receptor for advanced glycation end products is inversely associated with glycemic control and S100A12 protein. J. Clin. Endocrinol. Metab. 2006, 91:4628-4634.
21. Mori Y., Kosaki A., Kishimoto N., Kimura T., Iida K., Fukui M., Nakajima F., Nagahara M., Urakami M., Iwasaka T., Matsubara H. Increased plasma S100A12 (EN-RAGE) levels in hemodialysis patients with atherosclerosis. Am. J. Nephrol. 2009, 29:18-24.
22. Gawdzik J., Mathew L., Kim G., Puri T.S., Hofmann Bowman M.A. Vascular remodeling and arterial calcification are directly mediated by S100A12 (EN-RAGE) in chronic kidney disease. Am. J. Nephrol. 2011, 33:250-259.
23. Ebihara T., Endo R., Kikuta H., Ishiguro N., Ma X., Shimazu M., Otoguro T., Kobayashi K. Differential gene expression of S100 protein family in leukocytes from patients with Kawasaki disease. Eur. J. Pediatr. 2005, 164:427-431.
24. Mahajan N., Malik N., Bahl A., Dhawan V. Receptor for advanced glycation end products (RAGE) and its inflammatory ligand EN-RAGE in non-diabetic subjects with pre-mature coronary artery disease. Atherosclerosis 2009, 207:597-602.