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Volumn 8, Issue 4, 2013, Pages

Histatin 5 Resistance of Candida glabrata Can Be Reversed by Insertion of Candida albicans Polyamine Transporter-Encoding Genes DUR3 and DUR31

Author keywords

[No Author keywords available]

Indexed keywords

BETA 1,3 GLUCAN; HISTATIN 5; ANTIFUNGAL AGENT; FUNGAL PROTEIN; GLUCAN; HISTATIN; HTN3 PROTEIN, HUMAN; SPERMIDINE;

EID: 84876431369     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061480     Document Type: Article
Times cited : (20)

References (47)
  • 1
    • 33846466508 scopus 로고    scopus 로고
    • Epidemiology of invasive Candidiasis: a persistent public health problem
    • Pfaller MA, Diekema DJ, (2007) Epidemiology of invasive Candidiasis: a persistent public health problem. Clin Microbiol Rev 20: 133-163.
    • (2007) Clin Microbiol Rev , vol.20 , pp. 133-163
    • Pfaller, M.A.1    Diekema, D.J.2
  • 2
    • 3943093972 scopus 로고    scopus 로고
    • Nosocomial bloodstream infections in US Hospitals: analysis of 24,179 cases from a prospective Nationwide surveillance study
    • Wisplinghoff H, Bischoff T, Tallent SM, Seifert H, Wenzel RP, et al. (2004) Nosocomial bloodstream infections in US Hospitals: analysis of 24,179 cases from a prospective Nationwide surveillance study. Clin Infect Dis 39: 309-317.
    • (2004) Clin Infect Dis , vol.39 , pp. 309-317
    • Wisplinghoff, H.1    Bischoff, T.2    Tallent, S.M.3    Seifert, H.4    Wenzel, R.P.5
  • 3
    • 0344923836 scopus 로고    scopus 로고
    • Candida glabrata: Review of epidemiology, pathogenesis, and clinical disease with comparison to C. albicans
    • Fidel PL, Vazquez JA, Sobel JD, (1999) Candida glabrata: Review of epidemiology, pathogenesis, and clinical disease with comparison to C. albicans. Clin Microbiol Rev 12: 80-96.
    • (1999) Clin Microbiol Rev , vol.12 , pp. 80-96
    • Fidel, P.L.1    Vazquez, J.A.2    Sobel, J.D.3
  • 4
    • 0023888810 scopus 로고
    • Histatins, a novel family of histidine-rich proteins in human parotid secretion. Isolation, characterization, primary structure, and fungistatic effects on Candida albicans
    • Oppenheim FG, Xu T, McMillian FM, Levitz SM, Diamond RD, et al. (1988) Histatins, a novel family of histidine-rich proteins in human parotid secretion. Isolation, characterization, primary structure, and fungistatic effects on Candida albicans. J Biol Chem 263: 7472-7477.
    • (1988) J Biol Chem , vol.263 , pp. 7472-7477
    • Oppenheim, F.G.1    Xu, T.2    McMillian, F.M.3    Levitz, S.M.4    Diamond, R.D.5
  • 5
    • 0025237388 scopus 로고
    • Salivary histatin 5: dependence of sequence, chain length, and helical conformation for candidacidal activity
    • Raj PA, Edgerton M, Levine MJ, (1990) Salivary histatin 5: dependence of sequence, chain length, and helical conformation for candidacidal activity. J Biol Chem 265: 3898-3905.
    • (1990) J Biol Chem , vol.265 , pp. 3898-3905
    • Raj, P.A.1    Edgerton, M.2    Levine, M.J.3
  • 6
    • 0031984449 scopus 로고    scopus 로고
    • Structure of human salivary histatin 5 in aqueous and nonaqueous solutions
    • Raj PA, Marcus E, Sukumaran DK, (1998) Structure of human salivary histatin 5 in aqueous and nonaqueous solutions. Biopolymers 45: 51-67.
    • (1998) Biopolymers , vol.45 , pp. 51-67
    • Raj, P.A.1    Marcus, E.2    Sukumaran, D.K.3
  • 7
    • 0025733707 scopus 로고
    • Anticandidal activity of major human salivary histatins
    • Xu T, Levitz SM, Diamond RD, Oppenheim FG, (1991) Anticandidal activity of major human salivary histatins. Infect Immun 59: 2549-2554.
    • (1991) Infect Immun , vol.59 , pp. 2549-2554
    • Xu, T.1    Levitz, S.M.2    Diamond, R.D.3    Oppenheim, F.G.4
  • 8
    • 0030670607 scopus 로고    scopus 로고
    • Human salivary histatin-5 exerts potent fungicidal activity against Cryptococcus neoformans
    • Tsai H, Bobek LA, (1997) Human salivary histatin-5 exerts potent fungicidal activity against Cryptococcus neoformans. Biochim Biophys Acta 1336: 367-369.
    • (1997) Biochim Biophys Acta , vol.1336 , pp. 367-369
    • Tsai, H.1    Bobek, L.A.2
  • 9
    • 0032979798 scopus 로고    scopus 로고
    • Amphotericin B and fluconazole-resistant Candida spp., Aspergillus fumigatus, and other newly emerging pathogenic fungi are susceptible to basic antifungal peptides
    • Helmerhorst EJ, Reijnders IM, van't Hof W, Simoons-Smit I, Veerman EC, et al. (1999) Amphotericin B and fluconazole-resistant Candida spp., Aspergillus fumigatus, and other newly emerging pathogenic fungi are susceptible to basic antifungal peptides. Antimicrob Agents Chemother 43: 702-704.
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 702-704
    • Helmerhorst, E.J.1    Reijnders, I.M.2    van't Hof, W.3    Simoons-Smit, I.4    Veerman, E.C.5
  • 10
    • 23844506833 scopus 로고    scopus 로고
    • Candida glabrata is unusual with respect to its resistance to cationic antifungal proteins
    • Helmerhorst EJ, Venuleo C, Beri A, Oppenheim FG, (2005) Candida glabrata is unusual with respect to its resistance to cationic antifungal proteins. Yeast 22: 705-714.
    • (2005) Yeast , vol.22 , pp. 705-714
    • Helmerhorst, E.J.1    Venuleo, C.2    Beri, A.3    Oppenheim, F.G.4
  • 12
    • 0032734512 scopus 로고    scopus 로고
    • The ATP Binding Cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents
    • Sanglard D, Ischer F, Calabrese D, Majcherczyk PA, Bille J, (1999) The ATP Binding Cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents. Antimicrob Agents Chemother 43: 2753-2765.
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 2753-2765
    • Sanglard, D.1    Ischer, F.2    Calabrese, D.3    Majcherczyk, P.A.4    Bille, J.5
  • 13
    • 0035080323 scopus 로고    scopus 로고
    • Role of ATP-Binding-Cassette transporter genes in high-frequency acquisition of resistance to azole antifungals in Candida glabrata
    • Sanglard D, Ischer F, Bille J, (2001) Role of ATP-Binding-Cassette transporter genes in high-frequency acquisition of resistance to azole antifungals in Candida glabrata. Antimicrob Agents Chemother 45: 1174-1183.
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 1174-1183
    • Sanglard, D.1    Ischer, F.2    Bille, J.3
  • 14
    • 79952420944 scopus 로고    scopus 로고
    • Contribution of CgPDR1 regulated genes in enhanced virulence of azole-resistant Candida glabrata
    • Ferrari SlN, Sanguinetti M, Torelli R, Posteraro B, Sanglard D, (2011) Contribution of CgPDR1 regulated genes in enhanced virulence of azole-resistant Candida glabrata. PLoS ONE 6: e17589.
    • (2011) PLoS ONE , vol.6
    • Ferrari, S.L.N.1    Sanguinetti, M.2    Torelli, R.3    Posteraro, B.4    Sanglard, D.5
  • 15
    • 59249085257 scopus 로고    scopus 로고
    • Gain of function mutations in CgPDR1 of Candida glabrata not only mediate antifungal resistance but also enhance virulence
    • Ferrari SlN, Ischer Fo, Calabrese D, Posteraro B, Sanguinetti M, et al. (2009) Gain of function mutations in CgPDR1 of Candida glabrata not only mediate antifungal resistance but also enhance virulence. PLoS Pathog 5: e1000268.
    • (2009) PLoS Pathog , vol.5
    • Ferrari, S.L.N.1    Ischer, F.O.2    Calabrese, D.3    Posteraro, B.4    Sanguinetti, M.5
  • 16
    • 79952413922 scopus 로고    scopus 로고
    • Loss of mitochondrial functions associated with azole resistance in Candida glabrata results in enhanced virulence in mice
    • Ferrari SlN, Sanguinetti M, De Bernardis F, Torelli R, Posteraro B, et al. (2011) Loss of mitochondrial functions associated with azole resistance in Candida glabrata results in enhanced virulence in mice. Antimicrob Agents Chemother 55: 1852-1860.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 1852-1860
    • Ferrari, S.L.N.1    Sanguinetti, M.2    De Bernardis, F.3    Torelli, R.4    Posteraro, B.5
  • 18
    • 33644659723 scopus 로고    scopus 로고
    • Roles of cellular respiration, CgCDR1, and CgCDR2 in Candida glabrata resistance to Histatin 5
    • Helmerhorst EJ, Venuleo C, Sanglard D, Oppenheim FG, (2006) Roles of cellular respiration, CgCDR1, and CgCDR2 in Candida glabrata resistance to Histatin 5. Antimicrob Agents Chemother 50: 1100-1103.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 1100-1103
    • Helmerhorst, E.J.1    Venuleo, C.2    Sanglard, D.3    Oppenheim, F.G.4
  • 19
    • 0035807815 scopus 로고    scopus 로고
    • The human salivary peptide histatin 5 exerts its antifungal activity through the formation of reactive oxygen species
    • Helmerhorst EJ, Troxler RF, Oppenheim FG, (2001) The human salivary peptide histatin 5 exerts its antifungal activity through the formation of reactive oxygen species. Proc Natl Acad Sci 98: 14637-14642.
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 14637-14642
    • Helmerhorst, E.J.1    Troxler, R.F.2    Oppenheim, F.G.3
  • 20
    • 0033516461 scopus 로고    scopus 로고
    • Salivary histatin 5 induces non-lytic release of ATP from Candida albicans leading to cell death
    • Koshlukova SE, Lloyd TL, Araujo MWB, Edgerton M, (1999) Salivary histatin 5 induces non-lytic release of ATP from Candida albicans leading to cell death. J Biol Chem 274: 18872-18879.
    • (1999) J Biol Chem , vol.274 , pp. 18872-18879
    • Koshlukova, S.E.1    Lloyd, T.L.2    Araujo, M.W.B.3    Edgerton, M.4
  • 21
    • 77954352198 scopus 로고    scopus 로고
    • Salivary histatin 5 internalization by translocation, but not endocytosis, is required for fungicidal activity in Candida albicans
    • Jang WS, Bajwa JS, Sun JN, Edgerton M, (2010) Salivary histatin 5 internalization by translocation, but not endocytosis, is required for fungicidal activity in Candida albicans. Mol Microbiol 77: 354-370.
    • (2010) Mol Microbiol , vol.77 , pp. 354-370
    • Jang, W.S.1    Bajwa, J.S.2    Sun, J.N.3    Edgerton, M.4
  • 22
    • 55549117176 scopus 로고    scopus 로고
    • Uptake of the antifungal cationic peptide histatin 5 by Candida albicans Ssa2p requires binding to non-conventional sites within the ATPase domain
    • Sun JN, Li W, Jang WS, Nayyar N, Sutton MD, et al. (2008) Uptake of the antifungal cationic peptide histatin 5 by Candida albicans Ssa2p requires binding to non-conventional sites within the ATPase domain. Mol Microbiol 70: 1246-1260.
    • (2008) Mol Microbiol , vol.70 , pp. 1246-1260
    • Sun, J.N.1    Li, W.2    Jang, W.S.3    Nayyar, N.4    Sutton, M.D.5
  • 23
    • 33747331132 scopus 로고    scopus 로고
    • Candida albicans cell wall Ssa proteins bind and facilitate import of salivary histatin 5 required for toxicity
    • Li XS, Sun JN, Okamoto-Shibayama K, Edgerton M, (2006) Candida albicans cell wall Ssa proteins bind and facilitate import of salivary histatin 5 required for toxicity. J Biol Chem 281: 22453-22463.
    • (2006) J Biol Chem , vol.281 , pp. 22453-22463
    • Li, X.S.1    Sun, J.N.2    Okamoto-Shibayama, K.3    Edgerton, M.4
  • 24
    • 80855128823 scopus 로고    scopus 로고
    • New insights into the structure of (1→3,1→6)-β -D-Glucan side chains in the Candida glabrata cell wall
    • Lowman DW, West LJ, Bearden DW, Wempe MF, Power TD, et al. (2011) New insights into the structure of (1→3,1→6)-β-D-Glucan side chains in the Candida glabrata cell wall. PLoS ONE 6: e27614.
    • (2011) PLoS ONE , vol.6
    • Lowman, D.W.1    West, L.J.2    Bearden, D.W.3    Wempe, M.F.4    Power, T.D.5
  • 25
    • 78149258924 scopus 로고    scopus 로고
    • Recognition of yeast by murine macrophages requires mannan but not glucan
    • Keppler-Ross S, Douglas L, Konopka JB, Dean N, (2010) Recognition of yeast by murine macrophages requires mannan but not glucan. Eukaryot Cell 9: 1776-1787.
    • (2010) Eukaryot Cell , vol.9 , pp. 1776-1787
    • Keppler-Ross, S.1    Douglas, L.2    Konopka, J.B.3    Dean, N.4
  • 26
    • 84866147629 scopus 로고    scopus 로고
    • A Candida biofilm-induced pathway for matrix glucan delivery: implications for drug resistance
    • Taff HT, Nett JE, Zarnowski R, Ross KM, Sanchez H, et al. (2012) A Candida biofilm-induced pathway for matrix glucan delivery: implications for drug resistance. PLoS Pathog 8: e1002848.
    • (2012) PLoS Pathog , vol.8
    • Taff, H.T.1    Nett, J.E.2    Zarnowski, R.3    Ross, K.M.4    Sanchez, H.5
  • 28
    • 33747068293 scopus 로고    scopus 로고
    • Biofilm matrix of Candida albicans and Candida tropicalis: chemical composition and role in drug resistance
    • Al-Fattani MA, Douglas LJ, (2006) Biofilm matrix of Candida albicans and Candida tropicalis: chemical composition and role in drug resistance. J Med Microbiol 55: 999-1008.
    • (2006) J Med Microbiol , vol.55 , pp. 999-1008
    • Al-Fattani, M.A.1    Douglas, L.J.2
  • 29
    • 55449131941 scopus 로고    scopus 로고
    • The antimicrobial peptide Histatin-5 causes a spatially restricted disruption on the Candida albicans surface, allowing rapid entry of the peptide into the cytoplasm
    • Mochon AB, Liu H, (2008) The antimicrobial peptide Histatin-5 causes a spatially restricted disruption on the Candida albicans surface, allowing rapid entry of the peptide into the cytoplasm. PLoS Pathog 4: e1000190.
    • (2008) PLoS Pathog , vol.4
    • Mochon, A.B.1    Liu, H.2
  • 30
    • 83755171493 scopus 로고    scopus 로고
    • Histatin 5 uptake by Candida albicans utilizes polyamine transporters Dur3 and Dur31 proteins
    • Kumar R, Chadha S, Saraswat D, Bajwa JS, Li RA, et al. (2011) Histatin 5 uptake by Candida albicans utilizes polyamine transporters Dur3 and Dur31 proteins. J Biol Chem 286: 43748-43758.
    • (2011) J Biol Chem , vol.286 , pp. 43748-43758
    • Kumar, R.1    Chadha, S.2    Saraswat, D.3    Bajwa, J.S.4    Li, R.A.5
  • 31
    • 84861205386 scopus 로고    scopus 로고
    • The novel Candida albicans transporter Dur31 is a multi-stage pathogenicity factor
    • Mayer FoL, Wilson D, Jacobsen ID, Miramón P, Große K, et al. (2012) The novel Candida albicans transporter Dur31 is a multi-stage pathogenicity factor. PLoS Pathog 8: e1002592.
    • (2012) PLoS Pathog , vol.8
    • Mayer, F.O.L.1    Wilson, D.2    Jacobsen, I.D.3    Miramón, P.4    Große, K.5
  • 32
    • 0033824935 scopus 로고    scopus 로고
    • Matrix polymers of Candida biofilms and their possible role in biofilm resistance to antifungal agents
    • Baillie GS, Douglas LJ, (2000) Matrix polymers of Candida biofilms and their possible role in biofilm resistance to antifungal agents. J Antimicrob Chemother 46: 397-403.
    • (2000) J Antimicrob Chemother , vol.46 , pp. 397-403
    • Baillie, G.S.1    Douglas, L.J.2
  • 33
    • 67651235748 scopus 로고    scopus 로고
    • High-affinity transporters for NAD+precursors in Candida glabrata are regulated by Hst1 and induced in response to niacin limitation
    • Ma B, Pan S-J, Domergue R, Rigby T, Whiteway M, et al. (2009) High-affinity transporters for NAD+precursors in Candida glabrata are regulated by Hst1 and induced in response to niacin limitation. Mol Cell Biol 29: 4067-4079.
    • (2009) Mol Cell Biol , vol.29 , pp. 4067-4079
    • Ma, B.1    Pan, S.-J.2    Domergue, R.3    Rigby, T.4    Whiteway, M.5
  • 34
    • 55749100703 scopus 로고    scopus 로고
    • The cell wall of the human pathogen Candida glabrata: differential incorporation of novel adhesin-like wall proteins
    • de Groot PWJ, Kraneveld EA, Yin QY, Dekker HL, Groß U, et al. (2008) The cell wall of the human pathogen Candida glabrata: differential incorporation of novel adhesin-like wall proteins. Eukaryt Cell 7: 1951-1964.
    • (2008) Eukaryt Cell , vol.7 , pp. 1951-1964
    • de Groot, P.W.J.1    Kraneveld, E.A.2    Yin, Q.Y.3    Dekker, H.L.4    Groß, U.5
  • 35
    • 77956858246 scopus 로고    scopus 로고
    • Mass spectrometric analysis of the secretome of Candida albicans
    • Sorgo AG, Heilmann CJ, Dekker HL, Brul S, de Koster CG, et al. (2010) Mass spectrometric analysis of the secretome of Candida albicans. Yeast 27: 661-672.
    • (2010) Yeast , vol.27 , pp. 661-672
    • Sorgo, A.G.1    Heilmann, C.J.2    Dekker, H.L.3    Brul, S.4    de Koster, C.G.5
  • 36
    • 33947359453 scopus 로고    scopus 로고
    • Biofilm formation by and antifungal susceptibility of Candida isolates from urine
    • Jain N, Kohli R, Cook E, Gialanella P, Chang T, et al. (2007) Biofilm formation by and antifungal susceptibility of Candida isolates from urine. Appl Environ Microbiol 73: 1697-1703.
    • (2007) Appl Environ Microbiol , vol.73 , pp. 1697-1703
    • Jain, N.1    Kohli, R.2    Cook, E.3    Gialanella, P.4    Chang, T.5
  • 37
    • 0036840973 scopus 로고    scopus 로고
    • Antifungal activity of amphotericin b, fluconazole, and voriconazole in an in vitro model of Candida catheter-related bloodstream infection
    • Lewis RE, Kontoyiannis DP, Darouiche RO, Raad II, Prince RA, (2002) Antifungal activity of amphotericin b, fluconazole, and voriconazole in an in vitro model of Candida catheter-related bloodstream infection. Antimicrob Agents Chemother 46: 3499-3505.
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 3499-3505
    • Lewis, R.E.1    Kontoyiannis, D.P.2    Darouiche, R.O.3    Raad, I.I.4    Prince, R.A.5
  • 38
    • 34250340103 scopus 로고    scopus 로고
    • In vitro biofilm formation of Candida albicans and non-albicans Candida species under dynamic and anaerobic conditions
    • Thein ZM, Samaranayake YH, Samaranayake LP, (2007) In vitro biofilm formation of Candida albicans and non-albicans Candida species under dynamic and anaerobic conditions. Arch Oral Biol 52: 761-767.
    • (2007) Arch Oral Biol , vol.52 , pp. 761-767
    • Thein, Z.M.1    Samaranayake, Y.H.2    Samaranayake, L.P.3
  • 39
    • 4344670178 scopus 로고    scopus 로고
    • Penetration of Candida biofilms by antifungal agents
    • Al-Fattani MA, Douglas LJ, (2004) Penetration of Candida biofilms by antifungal agents. Antimicrob Agents Chemother 48: 3291-3297.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 3291-3297
    • Al-Fattani, M.A.1    Douglas, L.J.2
  • 41
    • 33748061642 scopus 로고    scopus 로고
    • Proteomic analysis of experimentally induced azole resistance in Candida glabrata
    • Rogers PD, Vermitsky JP, Edlind TD, Hilliard GM, (2006) Proteomic analysis of experimentally induced azole resistance in Candida glabrata. J Antimicrob Chemother 58: 434-438.
    • (2006) J Antimicrob Chemother , vol.58 , pp. 434-438
    • Rogers, P.D.1    Vermitsky, J.P.2    Edlind, T.D.3    Hilliard, G.M.4
  • 42
    • 0020529962 scopus 로고
    • Transformation of intact yeast cells treated with alkali cations
    • Ito H, Fukuda Y, Murata K, Kimura A, (1983) Transformation of intact yeast cells treated with alkali cations. J Bacteriol 153: 163-168.
    • (1983) J Bacteriol , vol.153 , pp. 163-168
    • Ito, H.1    Fukuda, Y.2    Murata, K.3    Kimura, A.4
  • 43
    • 38649127564 scopus 로고    scopus 로고
    • The P-113 fragment of histatin 5 requires a specific peptide sequence for intracellular translocation in Candida albicans, which is independent of cell wall binding
    • Jang WS, Li XS, Sun JN, Edgerton M, (2008) The P-113 fragment of histatin 5 requires a specific peptide sequence for intracellular translocation in Candida albicans, which is independent of cell wall binding. Antimicrob Agents Chemother 52: 497-504.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 497-504
    • Jang, W.S.1    Li, X.S.2    Sun, J.N.3    Edgerton, M.4
  • 44
    • 0027192868 scopus 로고
    • Isogenic strain construction and gene mapping in Candida albicans
    • Fonzi WA, Irwin MY, (1993) Isogenic strain construction and gene mapping in Candida albicans. Genetics 134: 717-728.
    • (1993) Genetics , vol.134 , pp. 717-728
    • Fonzi, W.A.1    Irwin, M.Y.2
  • 46
    • 0032981335 scopus 로고    scopus 로고
    • Efficient homologous and illegitimate recombination in the opportunistic yeast pathogen Candida glabrata
    • Cormack BP, Falkow S, (1999) Efficient homologous and illegitimate recombination in the opportunistic yeast pathogen Candida glabrata. Genetics 151: 979-987.
    • (1999) Genetics , vol.151 , pp. 979-987
    • Cormack, B.P.1    Falkow, S.2
  • 47
    • 1542513868 scopus 로고    scopus 로고
    • Human beta-defensins 2 and 3 demonstrate strain-selective activity against oral microorganisms
    • Joly S, Maze C, McCray PB Jr, Guthmiller JM, (2004) Human beta-defensins 2 and 3 demonstrate strain-selective activity against oral microorganisms. J Clin Microbiol 42: 1024-1029.
    • (2004) J Clin Microbiol , vol.42 , pp. 1024-1029
    • Joly, S.1    Maze, C.2    McCray Jr., P.B.3    Guthmiller, J.M.4


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