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Volumn 10, Issue 4, 2013, Pages 245-255

Progress and pitfalls in Shigella vaccine research

Author keywords

[No Author keywords available]

Indexed keywords

CVD 1204; CVD 1208; ENTEROTOXIN; GAMMA INTERFERON; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; INVAPLEX; INVASION PLASMID ANTIGEN PROTEIN; LIVE VACCINE; OUTER MEMBRANE PROTEIN; RECOMBINANT PSEUDOMONAS EXOPROTEIN A; SC 602; SECRETORY IMMUNOGLOBULIN; SHIGELLA ENTEROTOXIN 1; SHIGELLA ENTEROTOXIN 2; SHIGELLA FLEXNERI 2A LIPOPOLYSACCHARIDE CONJUGATE VACCINE; SHIGELLA SONNEI CONJUGATE VACCINE; SHIGELLA VACCINE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

EID: 84876419098     PISSN: 17595045     EISSN: 17595053     Source Type: Journal    
DOI: 10.1038/nrgastro.2013.12     Document Type: Review
Times cited : (117)

References (133)
  • 1
    • 0032879806 scopus 로고    scopus 로고
    • Global burden of Shigella infections: Implications for vaccine development and implementation of control strategies
    • Kotloff, K. L. et al. Global burden of Shigella infections: implications for vaccine development and implementation of control strategies. Bull. World Health Organ 77, 651-666 (1999).
    • (1999) Bull. World Health Organ , vol.77 , pp. 651-666
    • Kotloff, K.L.1
  • 2
    • 80054679292 scopus 로고    scopus 로고
    • Wide dissemination of multidrug-resistant Shigella isolates in China
    • Zhang, W. et al. Wide dissemination of multidrug-resistant Shigella isolates in China. J. Antimicrob. Chemother. 66, 2527-2535 (2011).
    • (2011) J. Antimicrob. Chemother. , vol.66 , pp. 2527-2535
    • Zhang, W.1
  • 3
    • 80053148934 scopus 로고    scopus 로고
    • Genetic characteristics and changing antimicrobial resistance among Shigella spp. isolated from hospitalized diarrhoeal patients in Kolkata
    • Ghosh, S. et al. Genetic characteristics and changing antimicrobial resistance among Shigella spp. isolated from hospitalized diarrhoeal patients in Kolkata, India. J. Med. Microbiol. 60, 1460-1466 (2011).
    • (2011) India. J. Med. Microbiol. , vol.60 , pp. 1460-1466
    • Ghosh, S.1
  • 4
    • 74049106610 scopus 로고    scopus 로고
    • A changing picture of shigellosis in southern Vietnam: Shifting species dominance, antimicrobial susceptibility and clinical presentation
    • Vinh, H. et al. A changing picture of shigellosis in southern Vietnam: shifting species dominance, antimicrobial susceptibility and clinical presentation. BMC Infect. Dis. 9, 204 (2009).
    • (2009) BMC Infect. Dis. , vol.9 , pp. 204
    • Vinh, H.1
  • 5
    • 79952475357 scopus 로고    scopus 로고
    • Changing species distribution and antimicrobial susceptibility pattern of Shigella over a 29-year period (1980-2008)
    • Khatun, F. et al. Changing species distribution and antimicrobial susceptibility pattern of Shigella over a 29-year period (1980-2008). Epidemiol. Infect. 139, 446-452 (2011).
    • (2011) Epidemiol. Infect. , vol.139 , pp. 446-452
    • Khatun, F.1
  • 6
    • 84861117535 scopus 로고    scopus 로고
    • Cephalosporin-resistant Shigella flexneri over 9 years (2001-2009) in India
    • Taneja, N., Mewara, A., Kumar, A., Verma, G. & Sharma, M. Cephalosporin-resistant Shigella flexneri over 9 years (2001-2009) in India. J. Antimicrob. Chemother. 67, 1347-1353 (2012).
    • (2012) J. Antimicrob. Chemother. , vol.67 , pp. 1347-1353
    • Taneja, N.1    Mewara, A.2    Kumar, A.3    Verma, G.4    Sharma, M.5
  • 7
    • 79953299664 scopus 로고    scopus 로고
    • Structural elucidation of the O-antigen of the Shigella flexneri provisional serotype 88-893: Structural and serological similarities with S. flexneri provisional serotype Y394 (1c)
    • Foster, R. A. et al. Structural elucidation of the O-antigen of the Shigella flexneri provisional serotype 88-893: structural and serological similarities with S. flexneri provisional serotype Y394 (1c). Carbohydr. Res. 346, 872-876 (2011).
    • (2011) Carbohydr. Res. , vol.346 , pp. 872-876
    • Foster, R.A.1
  • 8
    • 0015597232 scopus 로고
    • Pathogenesis of Shigella dysenteriae 1 (Shiga) dysentery
    • Levine, M. M. et al. Pathogenesis of Shigella dysenteriae 1 (Shiga) dysentery. J. Infect. Dis. 127, 261-270 (1973).
    • (1973) J. Infect. Dis. , vol.127 , pp. 261-270
    • Levine, M.M.1
  • 9
    • 0026069987 scopus 로고
    • Diarrheal disease during Operation Desert Shield
    • Hyams, K. C. et al. Diarrheal disease during Operation Desert Shield. N. Engl. J. Med. 325, 1423-1428 (1991).
    • (1991) N. Engl. J. Med. , vol.325 , pp. 1423-1428
    • Hyams, K.C.1
  • 10
    • 84870010706 scopus 로고    scopus 로고
    • The Global Enterics Multicenter Study (GEMS) of diarrheal disease in young children in developing countries: Epidemiologic and clinical methods of the case/control study
    • Kotloff, K. et al. The Global Enterics Multicenter Study (GEMS) of diarrheal disease in young children in developing countries: epidemiologic and clinical methods of the case/control study. Clin. Infect. Dis. 55 (Suppl. 4), S232-S245 (2012).
    • (2012) Clin. Infect. Dis. , vol.55 , Issue.SUPPL. 4
    • Kotloff, K.1
  • 11
    • 84870036414 scopus 로고    scopus 로고
    • Diagnostic microbiologic methods in the GEMS-1 Case/Control Study
    • Panchalingam, S. et al. Diagnostic microbiologic methods in the GEMS-1 Case/Control Study. Clin. Infect. Dis. 55 (Suppl. 4), S294-S302 (2012).
    • (2012) Clin. Infect. Dis. , vol.55 , Issue.SUPPL. 4
    • Panchalingam, S.1
  • 12
    • 34250353445 scopus 로고    scopus 로고
    • Clinical trials of Shigella vaccines: Two steps forward and one step back on a long, hard road
    • Levine, M. M., Kotloff, K. L., Barry, E. M., Pasetti, M. F. & Sztein, M. B. Clinical trials of Shigella vaccines: two steps forward and one step back on a long, hard road. Nat. Rev. Microbiol. 5, 540-553 (2007).
    • (2007) Nat. Rev. Microbiol. , vol.5 , pp. 540-553
    • Levine, M.M.1    Kotloff, K.L.2    Barry, E.M.3    Pasetti, M.F.4    Sztein, M.B.5
  • 13
    • 0028782818 scopus 로고
    • Health status of displaced persons following Cival War-Burundi, Dcemeber 1993-January 1994
    • Centers for Disease Control and Prevention.
    • Centers for Disease Control and Prevention. Health status of displaced persons following Cival War-Burundi, Dcemeber 1993-January 1994. MMWR Morb. Mortal. Wkly Rep. 43, 701-703 (1994).
    • (1994) MMWR Morb. Mortal. Wkly Rep. , vol.43 , pp. 701-703
  • 14
    • 0344959651 scopus 로고    scopus 로고
    • Strategy for cross-protection among Shigella flexneri serotypes
    • Noriega, F. R. et al. Strategy for cross-protection among Shigella flexneri serotypes. Infect. Immun. 67, 782-788 (1999).
    • (1999) Infect. Immun. , vol.67 , pp. 782-788
    • Noriega, F.R.1
  • 15
    • 18644378721 scopus 로고    scopus 로고
    • Genome sequence of Shigella flexneri 2a: Insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157
    • Jin, Q. et al. Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157. Nucleic Acids Res. 30, 4432-4441 (2002).
    • (2002) Nucleic Acids Res. , vol.30 , pp. 4432-4441
    • Jin, Q.1
  • 16
    • 28544440091 scopus 로고    scopus 로고
    • Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery
    • Yang, F. et al. Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery. Nucleic Acids Res. 33, 6445-6458 (2005).
    • (2005) Nucleic Acids Res. , vol.33 , pp. 6445-6458
    • Yang, F.1
  • 17
    • 28544435556 scopus 로고    scopus 로고
    • ShiBASE: An integrated database for comparative genomics of Shigella
    • Yang, J., Chen, L., Yu, J., Sun, L. & Jin, Q. ShiBASE: an integrated database for comparative genomics of Shigella. Nucleic Acids Res. 34, D398-D401 (2006).
    • (2006) Nucleic Acids Res. , vol.34
    • Yang, J.1    Chen, L.2    Yu, J.3    Sun, L.4    Jin, Q.5
  • 18
    • 0242416999 scopus 로고    scopus 로고
    • Complete genome sequence and comparative genomics of Shigella flexneri serotype 2a strain 2457T
    • Wei, J. et al. Complete genome sequence and comparative genomics of Shigella flexneri serotype 2a strain 2457T. Infect. Immun. 71, 2775-2786 (2003).
    • (2003) Infect. Immun. , vol.71 , pp. 2775-2786
    • Wei, J.1
  • 19
    • 30744457838 scopus 로고    scopus 로고
    • Immunoproteomics of membrane proteins of Shigella flexneri 2a 2457T
    • Ying, T. Y. et al. Immunoproteomics of membrane proteins of Shigella flexneri 2a 2457T. World J. Gastroenterol. 11, 6880-6883 (2005).
    • (2005) World J. Gastroenterol. , vol.11 , pp. 6880-6883
    • Ying, T.Y.1
  • 20
    • 33947181021 scopus 로고    scopus 로고
    • Shigella's ways of manipulating the host intestinal innate and adaptive immune system: A tool box for survival? Immunol
    • Phalipon, A. & Sansonetti, P. J. Shigella's ways of manipulating the host intestinal innate and adaptive immune system: a tool box for survival? Immunol. Cell Biol. 85, 119-129 (2007).
    • (2007) Cell Biol. , vol.85 , pp. 119-129
    • Phalipon, A.1    Sansonetti, P.J.2
  • 21
    • 38549126641 scopus 로고    scopus 로고
    • Molecular pathogenesis of Shigella spp.: Controlling host cell signaling, invasion, and death by type III secretion
    • Schroeder, G. N. & Hilbi, H. Molecular pathogenesis of Shigella spp.: controlling host cell signaling, invasion, and death by type III secretion. Clin. Microbiol. Rev. 21, 134-156 (2008).
    • (2008) Clin. Microbiol. Rev. , vol.21 , pp. 134-156
    • Schroeder, G.N.1    Hilbi, H.2
  • 23
    • 0022534788 scopus 로고
    • The role of Shigella spp., enteroinvasive Escherichia coli, and other enteropathogens as causes of childhood dysentery in Thailand
    • Taylor, D. N. et al. The role of Shigella spp., enteroinvasive Escherichia coli, and other enteropathogens as causes of childhood dysentery in Thailand. J. Infect. Dis. 153, 1132-1138 (1986).
    • (1986) J. Infect. Dis. , vol.153 , pp. 1132-1138
    • Taylor, D.N.1
  • 24
    • 0016633986 scopus 로고
    • Pathophysiology of Shigella diarrhea in the rhesus monkey: Intestinal transport, morphological, and bacteriological studies
    • Rout, W. R., Formal, S. B., Giannella, R. A. & Dammin, G. J. Pathophysiology of Shigella diarrhea in the rhesus monkey: intestinal transport, morphological, and bacteriological studies. Gastroenterology 68, 270-278 (1975).
    • (1975) Gastroenterology , vol.68 , pp. 270-278
    • Rout, W.R.1    Formal, S.B.2    Giannella, R.A.3    Dammin, G.J.4
  • 25
    • 0023149777 scopus 로고
    • Convulsions in childhood shigellosis. Clinical and laboratory features in 153 children
    • Ashkenazi, S., Dinari, G., Zevulunov, A. & Nitzan, M. Convulsions in childhood shigellosis. Clinical and laboratory features in 153 children. Am. J. Dis. Child 141, 208-210 (1987).
    • (1987) Am. J. Dis. Child , vol.141 , pp. 208-210
    • Ashkenazi, S.1    Dinari, G.2    Zevulunov, A.3    Nitzan, M.4
  • 26
    • 0018184036 scopus 로고
    • Hemolytic-uremic syndrome after shigellosis. Relation to endotoxemia and circulating immune complexes
    • Koster, F. et al. Hemolytic-uremic syndrome after shigellosis. Relation to endotoxemia and circulating immune complexes. N. Engl. J. Med. 298, 927-933 (1978).
    • (1978) N. Engl. J. Med. , vol.298 , pp. 927-933
    • Koster, F.1
  • 27
    • 0022359568 scopus 로고
    • Shigella septicemia: Prevalence, presentation, risk factors, and outcome
    • Struelens, M. J. et al. Shigella septicemia: prevalence, presentation, risk factors, and outcome. J. Infect. Dis. 152, 784-790 (1985).
    • (1985) J. Infect. Dis. , vol.152 , pp. 784-790
    • Struelens, M.J.1
  • 28
    • 0027054220 scopus 로고
    • Campylobacter and Shigella in HIV-seropositive patients
    • Nelson, M. R., Shanson, D. C., Hawkins, D. A. & Gazzard, B. G. Salmonella, Campylobacter and Shigella in HIV-seropositive patients. AIDS 6, 1495-1498 (1992).
    • (1992) AIDS , vol.6 , pp. 1495-1498
    • Nelson, M.R.1    Shanson, D.C.2    Hawkins, D.A.3    Salmonella, G.G.B.4
  • 29
    • 8244240428 scopus 로고    scopus 로고
    • Effect of Shigella enterotoxin 1 (ShET1) on rabbit intestine in vitro and in vivo
    • Fasano, A., Noriega, F. R., Liao, F. M., Wang, W. & Levine, M. M. Effect of Shigella enterotoxin 1 (ShET1) on rabbit intestine in vitro and in vivo. Gut 40, 505-511 (1997).
    • (1997) Gut , vol.40 , pp. 505-511
    • Fasano, A.1    Noriega, F.R.2    Liao, F.M.3    Wang, W.4    Levine, M.M.5
  • 30
    • 0029055743 scopus 로고
    • Shigella enterotoxin 1: An enterotoxin of Shigella flexneri 2a active in rabbit small intestine in vivo and in vitro
    • Fasano, A. et al. Shigella enterotoxin 1: an enterotoxin of Shigella flexneri 2a active in rabbit small intestine in vivo and in vitro. J. Clin. Invest. 95, 2853-2861 (1995).
    • (1995) J. Clin. Invest. , vol.95 , pp. 2853-2861
    • Fasano, A.1
  • 31
    • 79952607599 scopus 로고    scopus 로고
    • Shigella enterotoxin-2 is a type III effector that participates in Shigella-induced interleukin 8 secretion by epithelial cells
    • Farfan, M. J., Toro, C. S., Barry, E. M. & Nataro, J. P. Shigella enterotoxin-2 is a type III effector that participates in Shigella-induced interleukin 8 secretion by epithelial cells. FEMS Immunol. Med. Microbiol. 61, 332-339 (2011).
    • (2011) FEMS Immunol. Med. Microbiol. , vol.61 , pp. 332-339
    • Farfan, M.J.1    Toro, C.S.2    Barry, E.M.3    Nataro, J.P.4
  • 32
    • 8444230392 scopus 로고    scopus 로고
    • Deletion in the Shigella enterotoxin genes further attenuates Shigella flexneri 2a bearing guanine auxotrophy in a phase 1 trial of CVD 1204 and CVD 1208
    • Kotloff, K. L. et al. Deletion in the Shigella enterotoxin genes further attenuates Shigella flexneri 2a bearing guanine auxotrophy in a phase 1 trial of CVD 1204 and CVD 1208. J. Infect. Dis. 190, 1745-1754 (2004).
    • (2004) J. Infect. Dis. , vol.190 , pp. 1745-1754
    • Kotloff, K.L.1
  • 33
    • 37649000904 scopus 로고    scopus 로고
    • Safety and Immunogenicity of CVD 1208S, a live, oral ΔguaBA Δsen Δset Shigella flexneri 2a vaccine grown on animal-free media
    • Kotloff, K. L. et al. Safety and Immunogenicity of CVD 1208S, a live, oral ΔguaBA Δsen Δset Shigella flexneri 2a vaccine grown on animal-free media. Hum. Vaccin. 3, 268-275 (2007).
    • (2007) Hum. Vaccin. , vol.3 , pp. 268-275
    • Kotloff, K.L.1
  • 34
    • 84863780625 scopus 로고    scopus 로고
    • nd generation live attenuated vaccine candidates
    • nd generation live attenuated vaccine candidates. Vaccine 30, 5159-5171 (2012).
    • (2012) Vaccine , vol.30 , pp. 5159-5171
    • Ranallo, R.T.1
  • 35
    • 85046980853 scopus 로고    scopus 로고
    • Further characterization of Shigella sonnei live vaccine candidates WRSs2 and WRSs3-plasmid composition, invasion assays and Sereny reactions
    • Bedford, L. et al. Further characterization of Shigella sonnei live vaccine candidates WRSs2 and WRSs3-plasmid composition, invasion assays and Sereny reactions. Gut Microbes 2, 244-251 (2011).
    • (2011) Gut Microbes , vol.2 , pp. 244-251
    • Bedford, L.1
  • 36
    • 0036893427 scopus 로고    scopus 로고
    • Functional comparison of serine protease autotransporters of Enterobacteriaceae
    • Dutta, P. R., Cappello, R., Navarro-Garcia, F. & Nataro, J. P. Functional comparison of serine protease autotransporters of Enterobacteriaceae. Infect. Immun. 70, 7105-7113 (2002).
    • (2002) Infect. Immun. , vol.70 , pp. 7105-7113
    • Dutta, P.R.1    Cappello, R.2    Navarro-Garcia, F.3    Nataro, J.P.4
  • 37
    • 0034064649 scopus 로고    scopus 로고
    • The sigA gene which is borne on the she pathogenicity island of Shigella flexneri 2a encodes an exported cytopathic protease involved in intestinal fluid accumulation
    • Al-Hasani, K. et al. The sigA gene which is borne on the she pathogenicity island of Shigella flexneri 2a encodes an exported cytopathic protease involved in intestinal fluid accumulation. Infect. Immun. 68, 2457-2463 (2000).
    • (2000) Infect. Immun. , vol.68 , pp. 2457-2463
    • Al-Hasani, K.1
  • 39
    • 3543013141 scopus 로고    scopus 로고
    • SepA, the 110 kDa protein secreted by Shigella flexneri: Two-domain structure and proteolytic activity
    • Benjelloun-Touimi, Z., Si, T. M., Montecucco, C., Sansonetti, P. J. & Parsot, C. SepA, the 110 kDa protein secreted by Shigella flexneri: two-domain structure and proteolytic activity. Microbiology 144, 1815-1822 (1998).
    • (1998) Microbiology , vol.144 , pp. 1815-1822
    • Benjelloun-Touimi, Z.1    Si, T.M.2    Montecucco, C.3    Sansonetti, P.J.4    Parsot, C.5
  • 40
    • 84869224883 scopus 로고    scopus 로고
    • Chromosomal and plasmid-encoded factors of Shigella flexneri induce secretogenic activity ex vivo
    • Faherty, C. et al. Chromosomal and plasmid-encoded factors of Shigella flexneri induce secretogenic activity ex vivo. PLoS ONE 7, e49980 (2012).
    • (2012) PLoS ONE , vol.7
    • Faherty, C.1
  • 41
    • 0032734808 scopus 로고    scopus 로고
    • Characterization of Pic, a secreted protease of Shigella flexneri and enteroaggregative Escherichia coli
    • Henderson, I. R., Czeczulin, J., Eslava, C., Noriega, F. & Nataro, J. P. Characterization of Pic, a secreted protease of Shigella flexneri and enteroaggregative Escherichia coli. Infect. Immun. 67, 5587-5596 (1999).
    • (1999) Infect. Immun. , vol.67 , pp. 5587-5596
    • Henderson, I.R.1    Czeczulin, J.2    Eslava, C.3    Noriega, F.4    Nataro, J.P.5
  • 42
    • 0036259882 scopus 로고    scopus 로고
    • Regulation of the overlapping pic/set locus in Shigella flexneri and enteroaggregative Escherichia coli
    • Behrens, M., Sheikh, J. & Nataro, J. P. Regulation of the overlapping pic/set locus in Shigella flexneri and enteroaggregative Escherichia coli. Infect. Immun. 70, 2915-2925 (2002).
    • (2002) Infect. Immun. , vol.70 , pp. 2915-2925
    • Behrens, M.1    Sheikh, J.2    Nataro, J.P.3
  • 43
    • 79961216328 scopus 로고    scopus 로고
    • Serine protease autotransporters from Shigella flexneri and pathogenic Escherichia coli target a broad range of leukocyte glycoproteins
    • Ruiz-Perez, F. et al. Serine protease autotransporters from Shigella flexneri and pathogenic Escherichia coli target a broad range of leukocyte glycoproteins. Proc. Natl Acad. Sci. USA 108, 12881-12886 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 12881-12886
    • Ruiz-Perez, F.1
  • 44
    • 59649109832 scopus 로고    scopus 로고
    • Short report: High prevalence of serine protease autotransporter cytotoxins among strains of enteroaggregative Escherichia coli
    • Boisen, N., Ruiz-Perez, F., Scheutz, F., Krogfelt, K. A. & Nataro, J. P. Short report: high prevalence of serine protease autotransporter cytotoxins among strains of enteroaggregative Escherichia coli. Am. J. Trop. Med. Hyg. 80, 294-301 (2009).
    • (2009) Am. J. Trop. Med. Hyg. , vol.80 , pp. 294-301
    • Boisen, N.1    Ruiz-Perez, F.2    Scheutz, F.3    Krogfelt, K.A.4    Nataro, J.P.5
  • 45
    • 0013934204 scopus 로고
    • Protection of monkeys against experimental shigellosis with a living attenuated oral polyvalent dysentery vaccine
    • Formal, S. B. et al. Protection of monkeys against experimental shigellosis with a living attenuated oral polyvalent dysentery vaccine. J. Bacteriol. 92, 17-22 (1966).
    • (1966) J. Bacteriol. , vol.92 , pp. 17-22
    • Formal, S.B.1
  • 46
    • 0043136972 scopus 로고
    • Protection of monkeys against experimental shigellosis with attenuated vaccines
    • Formal, S. B., LaBrec, E. H., Palmer, A. & Falkow, S. Protection of monkeys against experimental shigellosis with attenuated vaccines. J. Bacteriol. 90, 63-68 (1965).
    • (1965) J. Bacteriol. , vol.90 , pp. 63-68
    • Formal, S.B.1    Labrec, E.H.2    Palmer, A.3    Falkow, S.4
  • 47
    • 77749270726 scopus 로고    scopus 로고
    • A challenge model for Shigella dysenteriae 1 in cynomolgus monkeys (Macaca fascicularis)
    • Shipley, S. T. et al. A challenge model for Shigella dysenteriae 1 in cynomolgus monkeys (Macaca fascicularis). Comp. Med. 60, 54-61 (2010).
    • (2010) Comp. Med. , vol.60 , pp. 54-61
    • Shipley, S.T.1
  • 48
    • 0029926843 scopus 로고    scopus 로고
    • Pathologic study of a rabbit model for shigellosis
    • Etheridge, M. E., Hoque, A. T. & Sack, D. A. Pathologic study of a rabbit model for shigellosis. Lab. Anim. Sci. 46, 61-66 (1996).
    • (1996) Lab. Anim. Sci. , vol.46 , pp. 61-66
    • Etheridge, M.E.1    Hoque, A.T.2    Sack, D.A.3
  • 49
    • 0028844180 scopus 로고
    • Development of an improved animal model of shigellosis in the adult rabbit by colonic infection with Shigella flexneri 2a
    • Rabbani, G. H. et al. Development of an improved animal model of shigellosis in the adult rabbit by colonic infection with Shigella flexneri 2a. Infect Immun. 63, 4350-4357 (1995).
    • (1995) Infect Immun. , vol.63 , pp. 4350-4357
    • Rabbani, G.H.1
  • 50
    • 84960986988 scopus 로고
    • Experimental Shigella keratoconjunctivitis; A preliminary report
    • Sereny, B. Experimental Shigella keratoconjunctivitis; a preliminary report. Acta Microbiol. Acad. Sci. Hung. 2, 293-296 (1955).
    • (1955) Acta Microbiol. Acad. Sci. Hung. , vol.2 , pp. 293-296
    • Sereny, B.1
  • 51
    • 0027518470 scopus 로고
    • Evaluation of Shigella vaccine safety and efficacy in an intranasally challenged mouse model
    • Mallett, C. P., VanDeVerg, L, Collins, H. H. & Hale, T. L. Evaluation of Shigella vaccine safety and efficacy in an intranasally challenged mouse model. Vaccine 11, 190-196 (1993).
    • (1993) Vaccine , vol.11 , pp. 190-196
    • Mallett, C.P.1    Vandeverg, L.2    Collins, H.H.3    Hale, T.L.4
  • 52
    • 33846898737 scopus 로고    scopus 로고
    • New animal model of shigellosis in the Guinea pig: Its usefulness for protective efficacy studies
    • Shim, D. H. et al. New animal model of shigellosis in the Guinea pig: its usefulness for protective efficacy studies. J. Immunol. 178, 2476-2482 (2007).
    • (2007) J. Immunol. , vol.178 , pp. 2476-2482
    • Shim, D.H.1
  • 53
    • 0028845225 scopus 로고
    • Identification and cloning of a novel plasmid-encoded enterotoxin of enteroinvasive Escherichia coli and Shigella strains
    • Nataro, J. P. et al. Identification and cloning of a novel plasmid-encoded enterotoxin of enteroinvasive Escherichia coli and Shigella strains. Infect. Immun. 63, 4721-4728 (1995).
    • (1995) Infect. Immun. , vol.63 , pp. 4721-4728
    • Nataro, J.P.1
  • 54
    • 0025997639 scopus 로고
    • Effect of prior infection with virulent Shigella flexneri 2a on the resistance of monkeys to subsequent infection with Shigella sonnei
    • Formal, S. B. et al. Effect of prior infection with virulent Shigella flexneri 2a on the resistance of monkeys to subsequent infection with Shigella sonnei. J. Infect Dis. 164, 533-537 (1991).
    • (1991) J. Infect Dis. , vol.164 , pp. 533-537
    • Formal, S.B.1
  • 55
    • 0025143614 scopus 로고
    • Studies in volunteers to evaluate candidate Shigella vaccines: Further experience with a bivalent Salmonella typhi-Shigella sonnei vaccine and protection conferred by previous Shigella sonnei disease
    • Herrington, D. A. et al. Studies in volunteers to evaluate candidate Shigella vaccines: further experience with a bivalent Salmonella typhi-Shigella sonnei vaccine and protection conferred by previous Shigella sonnei disease. Vaccine 8, 353-357 (1990).
    • (1990) Vaccine , vol.8 , pp. 353-357
    • Herrington, D.A.1
  • 56
    • 0028792307 scopus 로고
    • A modified Shigella volunteer challenge model in which the inoculum is administered with bicarbonate buffer: Clinical experience and implications for Shigella infectivity
    • Kotloff, K. L. et al. A modified Shigella volunteer challenge model in which the inoculum is administered with bicarbonate buffer: clinical experience and implications for Shigella infectivity. Vaccine 13, 1488-1494 (1995).
    • (1995) Vaccine , vol.13 , pp. 1488-1494
    • Kotloff, K.L.1
  • 57
    • 0025930596 scopus 로고
    • Epidemiologic patterns of acute diarrhea and endemic Shigella infections in children in a poor periurban setting in Santiago
    • Ferreccio, C. et al. Epidemiologic patterns of acute diarrhea and endemic Shigella infections in children in a poor periurban setting in Santiago, Chile. Am. J. Epidemiol. 134, 614-627 (1991).
    • (1991) Chile. Am. J. Epidemiol. , vol.134 , pp. 614-627
    • Ferreccio, C.1
  • 58
    • 0041736184 scopus 로고    scopus 로고
    • Safety and immunogenicity of Shigella sonnei-CRM9 and Shigella flexneri type 2a-rEPAsucc conjugate vaccines in one-to four-year-old children
    • Passwell, J. H. et al. Safety and immunogenicity of Shigella sonnei-CRM9 and Shigella flexneri type 2a-rEPAsucc conjugate vaccines in one-to four-year-old children. Pediatr. Infect. Dis. J. 22, 701-706 (2003).
    • (2003) Pediatr. Infect. Dis. J. , vol.22 , pp. 701-706
    • Passwell, J.H.1
  • 59
    • 0026748459 scopus 로고
    • Hypothesis for vaccine development: Protective immunity to enteric diseases caused by nontyphoidal salmonellae and shigellae may be conferred by serum IgG antibodies to the O-specific polysaccharide of their lipopolysaccharides
    • Robbins, J. B., Chu, C. & Schneerson, R. Hypothesis for vaccine development: protective immunity to enteric diseases caused by nontyphoidal salmonellae and shigellae may be conferred by serum IgG antibodies to the O-specific polysaccharide of their lipopolysaccharides. Clin. Infect Dis. 15, 346-361 (1992).
    • (1992) Clin. Infect Dis. , vol.15 , pp. 346-361
    • Robbins, J.B.1    Chu, C.2    Schneerson, R.3
  • 60
    • 0027203828 scopus 로고
    • Synthesis, characterization, and clinical evaluation of conjugate vaccines composed of the O-specific polysaccharides of Shigella dysenteriae type 1, Shigella flexneri type 2a, and Shigella sonnei (Plesiomonas shigelloides) bound to bacterial toxoids
    • Taylor, D. N. et al. Synthesis, characterization, and clinical evaluation of conjugate vaccines composed of the O-specific polysaccharides of Shigella dysenteriae type 1, Shigella flexneri type 2a, and Shigella sonnei (Plesiomonas shigelloides) bound to bacterial toxoids. Infect Immun. 61, 3678-3687 (1993).
    • (1993) Infect Immun. , vol.61 , pp. 3678-3687
    • Taylor, D.N.1
  • 61
    • 10144223600 scopus 로고    scopus 로고
    • Safety and immunogenicity of investigational Shigella conjugate vaccines in Israeli volunteers
    • Cohen, D. et al. Safety and immunogenicity of investigational Shigella conjugate vaccines in Israeli volunteers. Infect Immun. 64, 4074-4077 (1996).
    • (1996) Infect Immun. , vol.64 , pp. 4074-4077
    • Cohen, D.1
  • 62
    • 77049087280 scopus 로고    scopus 로고
    • Age-related efficacy of Shigella O-specific polysaccharide conjugates in 1-4-year-old Israeli children
    • Passwell, J. H. et al. Age-related efficacy of Shigella O-specific polysaccharide conjugates in 1-4-year-old Israeli children. Vaccine 28, 2231-2235 (2010).
    • (2010) Vaccine , vol.28 , pp. 2231-2235
    • Passwell, J.H.1
  • 63
    • 77955370642 scopus 로고    scopus 로고
    • Production of glycoprotein vaccines in Escherichia coli
    • Ihssen, J. et al. Production of glycoprotein vaccines in Escherichia coli. Microb. Cell Fact. 9, 61 (2010).
    • (2010) Microb. Cell Fact. , vol.9 , pp. 61
    • Ihssen, J.1
  • 64
    • 20044393802 scopus 로고    scopus 로고
    • Engineering N-linked protein glycosylation with diverse O antigen lipopolysaccharide structures in Escherichia coli
    • Feldman, M. F et al. Engineering N-linked protein glycosylation with diverse O antigen lipopolysaccharide structures in Escherichia coli. Proc. Natl Acad. Sci. USA 102, 3016-3021 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 3016-3021
    • Feldman, M.F.1
  • 66
    • 61449158708 scopus 로고    scopus 로고
    • A synthetic carbohydrate-protein conjugate vaccine candidate against Shigella flexneri 2a infection
    • Phalipon, A. et al. A synthetic carbohydrate-protein conjugate vaccine candidate against Shigella flexneri 2a infection. J. Immunol. 182, 2241-2247 (2009).
    • (2009) J. Immunol. , vol.182 , pp. 2241-2247
    • Phalipon, A.1
  • 67
    • 31144470173 scopus 로고    scopus 로고
    • Characterization of functional oligosaccharide mimics of the Shigella flexneri serotype 2a O-antigen: Implications for the development of a chemically defined glycoconjugate vaccine
    • Phalipon, A. et al. Characterization of functional oligosaccharide mimics of the Shigella flexneri serotype 2a O-antigen: implications for the development of a chemically defined glycoconjugate vaccine. J. Immunol. 176, 1686-1694 (2006).
    • (2006) J. Immunol. , vol.176 , pp. 1686-1694
    • Phalipon, A.1
  • 68
    • 33846196638 scopus 로고    scopus 로고
    • Vaccine potential for inactivated shigellae
    • Osorio, M., Bray, M. D. & Walker, R. I. Vaccine potential for inactivated shigellae. Vaccine 25, 1581-1592 (2007).
    • (2007) Vaccine , vol.25 , pp. 1581-1592
    • Osorio, M.1    Bray, M.D.2    Walker, R.I.3
  • 69
    • 33646474256 scopus 로고    scopus 로고
    • Safety and immunogenicity of an oral, inactivated, whole-cell vaccine for Shigella sonnei: Preclinical studies and a Phase i trial
    • McKenzie, R. et al. Safety and immunogenicity of an oral, inactivated, whole-cell vaccine for Shigella sonnei: preclinical studies and a Phase I trial. Vaccine 24, 3735-3745 (2006).
    • (2006) Vaccine , vol.24 , pp. 3735-3745
    • McKenzie, R.1
  • 71
    • 0032968361 scopus 로고    scopus 로고
    • Vaccination against shigellosis with attenuated Shigella flexneri 2a strain SC602
    • Coster, T. S. et al. Vaccination against shigellosis with attenuated Shigella flexneri 2a strain SC602. Infect. Immun. 67, 3437-3443 (1999).
    • (1999) Infect. Immun. , vol.67 , pp. 3437-3443
    • Coster, T.S.1
  • 72
    • 0001052629 scopus 로고
    • Studies on vaccination against bacillary dysentery. 3. Effective oral immunization against Shigella flexneri 2a in a field trial
    • Mel, D. M., Terzin, A. L. & Vuksic, L. Studies on vaccination against bacillary dysentery. 3. Effective oral immunization against Shigella flexneri 2a in a field trial. Bull. World Health Organ. 32, 647-655 (1965).
    • (1965) Bull. World Health Organ. , vol.32 , pp. 647-655
    • Mel, D.M.1    Terzin, A.L.2    Vuksic, L.3
  • 75
    • 80051569838 scopus 로고    scopus 로고
    • Shigella sonnei vaccine candidates WRSs2 and WRSs3 are as immunogenic as WRSS1, a clinically tested vaccine candidate, in a primate model of infection
    • Barnoy, S. et al. Shigella sonnei vaccine candidates WRSs2 and WRSs3 are as immunogenic as WRSS1, a clinically tested vaccine candidate, in a primate model of infection. Vaccine 29, 6371-6378 (2011).
    • (2011) Vaccine , vol.29 , pp. 6371-6378
    • Barnoy, S.1
  • 76
    • 73449131553 scopus 로고    scopus 로고
    • Virulence, inflammatory potential, and adaptive immunity induced by Shigella flexneri msbB mutants
    • Ranallo, R. T. et al. Virulence, inflammatory potential, and adaptive immunity induced by Shigella flexneri msbB mutants. Infect. Immun. 78, 400-412 (2010).
    • (2010) Infect. Immun. , vol.78 , pp. 400-412
    • Ranallo, R.T.1
  • 77
    • 10744231239 scopus 로고    scopus 로고
    • Two studies evaluating the safety and immunogenicity of a live, attenuated Shigella flexneri 2a vaccine (SC602) and excretion of vaccine organisms in North American volunteers
    • Katz, D. E. et al. Two studies evaluating the safety and immunogenicity of a live, attenuated Shigella flexneri 2a vaccine (SC602) and excretion of vaccine organisms in North American volunteers. Infect. Immun. 72, 923-930 (2004).
    • (2004) Infect. Immun. , vol.72 , pp. 923-930
    • Katz, D.E.1
  • 78
    • 78751578966 scopus 로고    scopus 로고
    • Safety, dose, immunogenicity, and transmissibility of an oral live attenuated Shigella flexneri 2a vaccine candidate (SC602) among healthy adults and school children in Matlab, Bangladesh
    • Rahman, K. M. et al. Safety, dose, immunogenicity, and transmissibility of an oral live attenuated Shigella flexneri 2a vaccine candidate (SC602) among healthy adults and school children in Matlab, Bangladesh. Vaccine 29, 1347-1354 (2011).
    • (2011) Vaccine , vol.29 , pp. 1347-1354
    • Rahman, K.M.1
  • 80
    • 77957375946 scopus 로고    scopus 로고
    • Immunogenicity and efficacy of oral vaccines in developing countries: Lessons from a live cholera vaccine
    • Levine, M. M. Immunogenicity and efficacy of oral vaccines in developing countries: lessons from a live cholera vaccine. BMC Biol. 8, 129 (2010).
    • (2010) BMC Biol. , vol.8 , pp. 129
    • Levine, M.M.1
  • 81
    • 0023274351 scopus 로고
    • Trial of an attenuated bovine rotavirus vaccine (RIT 4237) in Gambian infants
    • Hanlon, P. et al. Trial of an attenuated bovine rotavirus vaccine (RIT 4237) in Gambian infants. Lancet 1, 1342-1345 (1987).
    • (1987) Lancet , vol.1 , pp. 1342-1345
    • Hanlon, P.1
  • 82
    • 0015418159 scopus 로고
    • Oral polio vaccination of children in the tropics. I. the poor seroconversion rates and the absence of viral interference
    • John, T. J. & Jayabal, P. Oral polio vaccination of children in the tropics. I. The poor seroconversion rates and the absence of viral interference. Am. J. Epidemiol. 96, 263-269 (1972).
    • (1972) Am. J. Epidemiol. , vol.96 , pp. 263-269
    • John, T.J.1    Jayabal, P.2
  • 83
    • 77956063814 scopus 로고    scopus 로고
    • Efficacy of pentavalent rotavirus vaccine against severe rotavirus gastroenteritis in infants in developing countries in sub-Saharan Africa: A randomised, doubleblind, placebo-controlled trial
    • Armah, G. E. et al. Efficacy of pentavalent rotavirus vaccine against severe rotavirus gastroenteritis in infants in developing countries in sub-Saharan Africa: a randomised, doubleblind, placebo-controlled trial. Lancet 376, 606-614 (2010).
    • (2010) Lancet , vol.376 , pp. 606-614
    • Armah, G.E.1
  • 84
    • 0025197717 scopus 로고
    • Efficacy of oral poliovirus vaccine in rural communities of North Arcot District, India
    • Balraj, V., John, T. J., Thomas, M. & Mukundan, S. Efficacy of oral poliovirus vaccine in rural communities of North Arcot District, India. Int. J. Epidemiol. 19, 711-714 (1990).
    • (1990) Int. J. Epidemiol. , vol.19 , pp. 711-714
    • Balraj, V.1    John, T.J.2    Thomas, M.3    Mukundan, S.4
  • 85
    • 75449098835 scopus 로고    scopus 로고
    • Effect of human rotavirus vaccine on severe diarrhea in African infants
    • Madhi, S. A. et al. Effect of human rotavirus vaccine on severe diarrhea in African infants. N. Engl. J. Med. 362, 289-298 (2010).
    • (2010) N. Engl. J. Med. , vol.362 , pp. 289-298
    • Madhi, S.A.1
  • 86
    • 0026596515 scopus 로고
    • Safety and immunogenicity of different immunization regimens of CVD 103-HgR live oral cholera vaccine in soldiers and civilians in Thailand
    • Su-Arehawaratana, P. et al. Safety and immunogenicity of different immunization regimens of CVD 103-HgR live oral cholera vaccine in soldiers and civilians in Thailand. J. Infect. Dis. 165, 1042-1048 (1992).
    • (1992) J. Infect. Dis. , vol.165 , pp. 1042-1048
    • Su-Arehawaratana, P.1
  • 87
    • 39249084015 scopus 로고    scopus 로고
    • Immunogenicity and efficacy of highly purified invasin complex vaccine from Shigella flexneri 2a
    • Turbyfill, K. R., Kaminski, R. W. & Oaks, E. V. Immunogenicity and efficacy of highly purified invasin complex vaccine from Shigella flexneri 2a. Vaccine 26, 1353-1364 (2008).
    • (2008) Vaccine , vol.26 , pp. 1353-1364
    • Turbyfill, K.R.1    Kaminski, R.W.2    Oaks, E.V.3
  • 88
    • 80052307654 scopus 로고    scopus 로고
    • Safety and immunogenicity of an intranasal Shigella flexneri 2a Invaplex 50 vaccine
    • Riddle, M. S. et al. Safety and immunogenicity of an intranasal Shigella flexneri 2a Invaplex 50 vaccine. Vaccine 29, 7009-7019 (2011).
    • (2011) Vaccine , vol.29 , pp. 7009-7019
    • Riddle, M.S.1
  • 89
    • 77955509224 scopus 로고    scopus 로고
    • Safety and immunogenicity of a Shigella flexneri 2a Invaplex 50 intranasal vaccine in adult volunteers
    • Tribble, D. et al. Safety and immunogenicity of a Shigella flexneri 2a Invaplex 50 intranasal vaccine in adult volunteers. Vaccine 28, 6076-6085 (2010).
    • (2010) Vaccine , vol.28 , pp. 6076-6085
    • Tribble, D.1
  • 90
    • 84857681855 scopus 로고    scopus 로고
    • Broadly protective Shigella vaccine based on type III secretion apparatus proteins
    • Martinez-Becerra, F. J. et al. Broadly protective Shigella vaccine based on type III secretion apparatus proteins. Infect. Immun. 80, 1222-1231 (2012).
    • (2012) Infect. Immun. , vol.80 , pp. 1222-1231
    • Martinez-Becerra, F.J.1
  • 91
    • 0028086290 scopus 로고
    • Serum IgG antibody responses to Shigella invasion plasmid-coded antigens detected by immunoblot
    • Li, A., Zhao, C. R., Ekwall, E. & Lindberg, A. A. Serum IgG antibody responses to Shigella invasion plasmid-coded antigens detected by immunoblot. Scand. J. Infect. Dis. 26, 435-445 (1994).
    • (1994) Scand. J. Infect. Dis. , vol.26 , pp. 435-445
    • Li, A.1    Zhao, C.R.2    Ekwall, E.3    Lindberg, A.A.4
  • 92
    • 0022530652 scopus 로고
    • Serum immune response to Shigella protein antigens in rhesus monkeys and humans infected with Shigella spp
    • Oaks, E. V., Hale, T. L. & Formal, S. B. Serum immune response to Shigella protein antigens in rhesus monkeys and humans infected with Shigella spp. Infect. Immun. 53, 57-63 (1986).
    • (1986) Infect. Immun. , vol.53 , pp. 57-63
    • Oaks, E.V.1    Hale, T.L.2    Formal, S.B.3
  • 93
    • 0018930035 scopus 로고
    • Protection against keratoconjunctivitis shigellosa induced by immunization with outer membrane proteins of Shigella spp
    • Adamus, G., Mulczyk, M., Witkowska, D. & Romanowska, E. Protection against keratoconjunctivitis shigellosa induced by immunization with outer membrane proteins of Shigella spp. Infect. Immun. 30, 321-324 (1980).
    • (1980) Infect. Immun. , vol.30 , pp. 321-324
    • Adamus, G.1    Mulczyk, M.2    Witkowska, D.3    Romanowska, E.4
  • 94
    • 79960758250 scopus 로고    scopus 로고
    • Outer membrane protein A (OmpA) of Shigella flexneri 2a, induces protective immune response in a mouse model
    • Pore, D., Mahata, N., Pal, A. & Chakrabarti, M. K. Outer membrane protein A (OmpA) of Shigella flexneri 2a, induces protective immune response in a mouse model. PLoS ONE 6, e22663 (2011).
    • (2011) PLoS ONE , vol.6
    • Pore, D.1    Mahata, N.2    Pal, A.3    Chakrabarti, M.K.4
  • 95
    • 84862018230 scopus 로고    scopus 로고
    • High yield production process for Shigella outer membrane particles
    • Berlanda Scorza, F. et al. High yield production process for Shigella outer membrane particles. PLoS ONE 7, e35616 (2012).
    • (2012) PLoS ONE , vol.7
    • Berlanda Scorza, F.1
  • 96
    • 0030898197 scopus 로고    scopus 로고
    • Characterization and quantitative analysis of serum IgG class and subclass response to Shigella sonnei and Shigella flexneri 2a lipopolysaccharide following natural Shigella infection
    • Robin, G. et al. Characterization and quantitative analysis of serum IgG class and subclass response to Shigella sonnei and Shigella flexneri 2a lipopolysaccharide following natural Shigella infection. J. Infect. Dis. 175, 1128-1133 (1997).
    • (1997) J. Infect. Dis. , vol.175 , pp. 1128-1133
    • Robin, G.1
  • 97
    • 0023896030 scopus 로고
    • Serum antibodies to lipopolysaccharide and natural immunity to shigellosis in an Israeli military population
    • Cohen, D., Green, M. S., Block, C., Rouach, T. & Ofek, I. Serum antibodies to lipopolysaccharide and natural immunity to shigellosis in an Israeli military population. J. Infect. Dis. 157, 1068-1071 (1988).
    • (1988) J. Infect. Dis. , vol.157 , pp. 1068-1071
    • Cohen, D.1    Green, M.S.2    Block, C.3    Rouach, T.4    Ofek, I.5
  • 98
    • 0025967987 scopus 로고
    • Prospective study of the association between serum antibodies to lipopolysaccharide O antigen and the attack rate of shigellosis
    • Cohen, D., Green, M. S., Block, C., Slepon, R. & Ofek, I. Prospective study of the association between serum antibodies to lipopolysaccharide O antigen and the attack rate of shigellosis. J. Clin. Microbiol. 29, 386-389 (1991).
    • (1991) J. Clin. Microbiol. , vol.29 , pp. 386-389
    • Cohen, D.1    Green, M.S.2    Block, C.3    Slepon, R.4    Ofek, I.5
  • 99
    • 0026719589 scopus 로고
    • Age-specific prevalence of serum antibodies to the invasion plasmid and lipopolysaccharide antigens of Shigella species in Chilean and North American populations
    • Van De Verg, L. L., Herrington, D. A., Boslego, J., Lindberg, A. A. & Levine, M. M. Age-specific prevalence of serum antibodies to the invasion plasmid and lipopolysaccharide antigens of Shigella species in Chilean and North American populations. J. Infect. Dis. 166, 158-161 (1992).
    • (1992) J. Infect. Dis. , vol.166 , pp. 158-161
    • Van De Verg, L.L.1    Herrington, D.A.2    Boslego, J.3    Lindberg, A.A.4    Levine, M.M.5
  • 100
    • 0025883165 scopus 로고
    • Prospective study of systemic and mucosal immune responses in dysenteric patients to specific Shigella invasion plasmid antigens and lipopolysaccharides
    • Oberhelman, R. A. et al. Prospective study of systemic and mucosal immune responses in dysenteric patients to specific Shigella invasion plasmid antigens and lipopolysaccharides. Infect. Immun. 59, 2341-2350 (1991).
    • (1991) Infect. Immun. , vol.59 , pp. 2341-2350
    • Oberhelman, R.A.1
  • 101
    • 83455219853 scopus 로고    scopus 로고
    • Differential host immune responses to epidemic and endemic strains of Shigella dysenteriae type i
    • Sayem, M. A. et al. Differential host immune responses to epidemic and endemic strains of Shigella dysenteriae type I. J. Health Popul. Nutr. 29, 429-437 (2011).
    • (2011) J. Health Popul. Nutr. , vol.29 , pp. 429-437
    • Sayem, M.A.1
  • 102
    • 0019131457 scopus 로고
    • Antibody-dependent cellmediated antibacterial activity: K lymphocytes, monocytes, and granulocytes are effective against Shigella
    • Lowell, G. H. et al. Antibody-dependent cellmediated antibacterial activity: K lymphocytes, monocytes, and granulocytes are effective against Shigella. J. Immunol. 125, 2778-2784 (1980).
    • (1980) J. Immunol. , vol.125 , pp. 2778-2784
    • Lowell, G.H.1
  • 103
    • 0029859443 scopus 로고    scopus 로고
    • Safety, immunogenicity, and transmissibility in humans of CVD 1203, a live oral Shigella flexneri 2a vaccine candidate attenuated by deletions in aroA and virG
    • Kotloff, K. L. et al. Safety, immunogenicity, and transmissibility in humans of CVD 1203, a live oral Shigella flexneri 2a vaccine candidate attenuated by deletions in aroA and virG. Infect. Immun. 64, 4542-4548 (1996).
    • (1996) Infect. Immun. , vol.64 , pp. 4542-4548
    • Kotloff, K.L.1
  • 104
    • 0028956405 scopus 로고
    • Evaluation of the safety, immunogenicity, and efficacy in healthy adults of four doses of live oral hybrid Escherichia coli-Shigella flexneri 2a vaccine strain EcSf2a-2
    • Kotloff, K. L. et al. Evaluation of the safety, immunogenicity, and efficacy in healthy adults of four doses of live oral hybrid Escherichia coli-Shigella flexneri 2a vaccine strain EcSf2a-2. Vaccine 13, 495-502 (1995).
    • (1995) Vaccine , vol.13 , pp. 495-502
    • Kotloff, K.L.1
  • 105
    • 0026495090 scopus 로고
    • Concentration of milk secretor y immunoglobulin A against Shigella virulence plasmid-associated antigens as a predictor of symptom status in Shigella-infected breast-fed infants
    • Hayani, K. C. et al. Concentration of milk secretor y immunoglobulin A against Shigella virulence plasmid-associated antigens as a predictor of symptom status in Shigella-infected breast-fed infants. J. Pediatr. 121, 852-856 (1992).
    • (1992) J. Pediatr. , vol.121 , pp. 852-856
    • Hayani, K.C.1
  • 106
    • 0024403162 scopus 로고
    • Human milk immunoglobulin A antibodies to Shigella virulence determinants
    • Cleary, T. G., Winsor, D. K., Reich, D., Ruiz-Palacios, G. & Calva, J. J. Human milk immunoglobulin A antibodies to Shigella virulence determinants. Infect. Immun. 57, 1675-1679 (1989).
    • (1989) Infect. Immun. , vol.57 , pp. 1675-1679
    • Cleary, T.G.1    Winsor, D.K.2    Reich, D.3    Ruiz-Palacios, G.4    Calva, J.J.5
  • 107
    • 0031036053 scopus 로고    scopus 로고
    • Double-blind vaccine-controlled randomised efficacy trial of an investigational Shigella sonnei conjugate vaccine in young adults
    • Cohen, D. et al. Double-blind vaccine-controlled randomised efficacy trial of an investigational Shigella sonnei conjugate vaccine in young adults. Lancet 349, 155-159 (1997).
    • (1997) Lancet , vol.349 , pp. 155-159
    • Cohen, D.1
  • 108
    • 0028847731 scopus 로고
    • Persistence of local cytokine production in shigellosis in acute and convalescent stages
    • Raqib, R. et al. Persistence of local cytokine production in shigellosis in acute and convalescent stages. Infect. Immun. 63, 289-296 (1995).
    • (1995) Infect. Immun. , vol.63 , pp. 289-296
    • Raqib, R.1
  • 109
    • 0036225752 scopus 로고    scopus 로고
    • Delayed and reduced adaptive humoral immune responses in children with shigellosis compared with in adults
    • Raqib, R. et al. Delayed and reduced adaptive humoral immune responses in children with shigellosis compared with in adults. Scand. J. Immunol. 55, 414-423 (2002).
    • (2002) Scand. J. Immunol. , vol.55 , pp. 414-423
    • Raqib, R.1
  • 110
    • 0034029529 scopus 로고    scopus 로고
    • Disease-dependent changes in T-cell populations in patients with shigellosis
    • Islam, D. & Christensson, B. Disease-dependent changes in T-cell populations in patients with shigellosis. APMIS 108, 251-260 (2000).
    • (2000) APMIS , vol.108 , pp. 251-260
    • Islam, D.1    Christensson, B.2
  • 111
    • 0029100715 scopus 로고
    • Shigella infection induces cellular activation of T and B cells and distinct species-related changes in peripheral blood lymphocyte subsets during the course of the disease
    • Islam, D., Bardhan, P. K., Lindberg, A. A. & Christensson, B. Shigella infection induces cellular activation of T and B cells and distinct species-related changes in peripheral blood lymphocyte subsets during the course of the disease. Infect. Immun. 63, 2941-2949 (1995).
    • (1995) Infect. Immun. , vol.63 , pp. 2941-2949
    • Islam, D.1    Bardhan, P.K.2    Lindberg, A.A.3    Christensson, B.4
  • 112
    • 0030007429 scopus 로고    scopus 로고
    • Changes in the peripheral blood T-cell receptor v beta repertoire in vivo and in vitro during shigellosis
    • Islam, D., Wretlind, B., Lindberg, A. A. & Christensson, B. Changes in the peripheral blood T-cell receptor V beta repertoire in vivo and in vitro during shigellosis. Infect. Immun. 64, 1391-1399 (1996).
    • (1996) Infect. Immun. , vol.64 , pp. 1391-1399
    • Islam, D.1    Wretlind, B.2    Lindberg, A.A.3    Christensson, B.4
  • 113
    • 56249130033 scopus 로고    scopus 로고
    • Retinoic acid-dependent regulation of immune responses by dendritic cells and macrophages
    • Manicassamy, S. & Pulendran, B. Retinoic acid-dependent regulation of immune responses by dendritic cells and macrophages. Semin. Immunol. 21, 22-27 (2009).
    • (2009) Semin. Immunol. , vol.21 , pp. 22-27
    • Manicassamy, S.1    Pulendran, B.2
  • 114
    • 84870252354 scopus 로고    scopus 로고
    • New concepts in the generation and functions of IgA
    • Pabst, O. New concepts in the generation and functions of IgA. Nat. Rev. Immunol. 12, 821-832 (2012).
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 821-832
    • Pabst, O.1
  • 115
    • 39649095149 scopus 로고    scopus 로고
    • Phenotypic and functional heterogeneity of human memory B cells
    • Sanz, I., Wei, C., Lee, F. E. & Anolik, J. Phenotypic and functional heterogeneity of human memory B cells. Semin. Immunol. 20, 67-82 (2008).
    • (2008) Semin. Immunol. , vol.20 , pp. 67-82
    • Sanz, I.1    Wei, C.2    Lee, F.E.3    Anolik, J.4
  • 116
    • 57749189113 scopus 로고    scopus 로고
    • Antigen-specific B memory cell responses to lipopolysaccharide (LPS) and invasion plasmid antigen (Ipa) B elicited in volunteers vaccinated with live-attenuated Shigella flexneri 2a vaccine candidates
    • Simon, J. K. et al. Antigen-specific B memory cell responses to lipopolysaccharide (LPS) and invasion plasmid antigen (Ipa) B elicited in volunteers vaccinated with live-attenuated Shigella flexneri 2a vaccine candidates. Vaccine 27, 565-572 (2009).
    • (2009) Vaccine , vol.27 , pp. 565-572
    • Simon, J.K.1
  • 117
    • 79954615124 scopus 로고    scopus 로고
    • Antigen-specific IgA B memory cell responses to Shigella antigens elicited in volunteers immunized with live attenuated Shigella flexneri 2a oral vaccine candidates
    • Simon, J. K. et al. Antigen-specific IgA B memory cell responses to Shigella antigens elicited in volunteers immunized with live attenuated Shigella flexneri 2a oral vaccine candidates. Clin. Immunol. 139, 185-192 (2011).
    • (2011) Clin. Immunol. , vol.139 , pp. 185-192
    • Simon, J.K.1
  • 118
    • 0037650212 scopus 로고    scopus 로고
    • Antigen dependent and independent mechanisms that sustain serum antibody levels
    • Traggiai, E., Puzone, R. & Lanzavecchia, A. Antigen dependent and independent mechanisms that sustain serum antibody levels. Vaccine 21 (Suppl. 2), S35-S37 (2003).
    • (2003) Vaccine , vol.21 , Issue.SUPPL. 2
    • Traggiai, E.1    Puzone, R.2    Lanzavecchia, A.3
  • 119
    • 68349131614 scopus 로고    scopus 로고
    • Vaccination of children in low-resource countries against Shigella is unlikely to present an undue risk of reactive arthritis
    • Gaston, J. S. et al. Vaccination of children in low-resource countries against Shigella is unlikely to present an undue risk of reactive arthritis. Vaccine 27, 5432-5434 (2009).
    • (2009) Vaccine , vol.27 , pp. 5432-5434
    • Gaston, J.S.1
  • 120
    • 0028809478 scopus 로고
    • Prevalence of Shigella enterotoxin 1 among Shigella clinical isolates of diverse serotypes
    • Noriega, F. R., Liao, F. M., Formal, S. B., Fasano, A. & Levine, M. M. Prevalence of Shigella enterotoxin 1 among Shigella clinical isolates of diverse serotypes. J. Infect. Dis. 172, 1408-1410 (1995).
    • (1995) J. Infect. Dis. , vol.172 , pp. 1408-1410
    • Noriega, F.R.1    Liao, F.M.2    Formal, S.B.3    Fasano, A.4    Levine, M.M.5
  • 121
    • 0029166295 scopus 로고
    • SepA, the major extracellular protein of Shigella flexneri: Autonomous secretion and involvement in tissue invasion
    • Benjelloun-Touimi, Z., Sansonetti, P. J. & Parsot, C. SepA, the major extracellular protein of Shigella flexneri: autonomous secretion and involvement in tissue invasion. Mol. Microbiol. 17, 123-135 (1995).
    • (1995) Mol. Microbiol. , vol.17 , pp. 123-135
    • Benjelloun-Touimi, Z.1    Sansonetti, P.J.2    Parsot, C.3
  • 122
    • 84855733490 scopus 로고    scopus 로고
    • Live attenuated Shigella dysenteriae type 1 vaccine strains overexpressing shiga toxin B subunit
    • Wu, T., Grassel, C., Levine, M. M. & Barry, E. M. Live attenuated Shigella dysenteriae type 1 vaccine strains overexpressing shiga toxin B subunit. Infect. Immun. 79, 4912-4922 (2011).
    • (2011) Infect. Immun. , vol.79 , pp. 4912-4922
    • Wu, T.1    Grassel, C.2    Levine, M.M.3    Barry, E.M.4
  • 123
    • 0036128648 scopus 로고    scopus 로고
    • Phase i evaluation of delta virG Shigella sonnei live, attenuated, oral vaccine strain WRSS1 in healthy adults
    • Kotloff, K. L. et al. Phase I evaluation of delta virG Shigella sonnei live, attenuated, oral vaccine strain WRSS1 in healthy adults. Infect. Immun. 70, 2016-2021 (2002).
    • (2002) Infect. Immun. , vol.70 , pp. 2016-2021
    • Kotloff, K.L.1
  • 124
    • 75249084778 scopus 로고    scopus 로고
    • Characterization of WRSs2 and WRSs3, new second-generation virG(icsA)-based Shigella sonnei vaccine candidates with the potential for reduced reactogenicity
    • Barnoy, S. et al. Characterization of WRSs2 and WRSs3, new second-generation virG(icsA)-based Shigella sonnei vaccine candidates with the potential for reduced reactogenicity. Vaccine 28, 1642-1654 (2010).
    • (2010) Vaccine , vol.28 , pp. 1642-1654
    • Barnoy, S.1
  • 125
    • 40949121054 scopus 로고    scopus 로고
    • Safety and colonization of two novel VirG(IcsA)-based live Shigella sonnei vaccine strains in rhesus macaques (Macaca mulatta)
    • Collins, T. A. et al. Safety and colonization of two novel VirG(IcsA)-based live Shigella sonnei vaccine strains in rhesus macaques (Macaca mulatta). Comp. Med. 58, 88-94 (2008).
    • (2008) Comp. Med. , vol.58 , pp. 88-94
    • Collins, T.A.1
  • 126
    • 33846885007 scopus 로고    scopus 로고
    • Immunogenicity and characterization of WRSF2G11: A second generation live attenuated Shigella flexneri 2a vaccine strain
    • Ranallo, R. T., Thakkar, S., Chen, Q. & Venkatesan, M. M. Immunogenicity and characterization of WRSF2G11: a second generation live attenuated Shigella flexneri 2a vaccine strain. Vaccine 25, 2269-2278 (2007).
    • (2007) Vaccine , vol.25 , pp. 2269-2278
    • Ranallo, R.T.1    Thakkar, S.2    Chen, Q.3    Venkatesan, M.M.4
  • 127
    • 44749092472 scopus 로고    scopus 로고
    • Safety and immunogenicity of WRSd1, a live attenuated Shigella dysenteriae type 1 vaccine candidate
    • McKenzie, R. et al. Safety and immunogenicity of WRSd1, a live attenuated Shigella dysenteriae type 1 vaccine candidate. Vaccine 26, 3291-3296 (2008).
    • (2008) Vaccine , vol.26 , pp. 3291-3296
    • McKenzie, R.1
  • 128
    • 0036263522 scopus 로고    scopus 로고
    • Construction, characterization, and animal testing of WRSd1, a Shigella dysenteriae 1 vaccine
    • Venkatesan, M. M. et al. Construction, characterization, and animal testing of WRSd1, a Shigella dysenteriae 1 vaccine. Infect. Immun. 70, 2950-2958 (2002).
    • (2002) Infect. Immun. , vol.70 , pp. 2950-2958
    • Venkatesan, M.M.1
  • 129
    • 9044225141 scopus 로고    scopus 로고
    • Clinical trials of Shigella vaccines in Israel
    • Cohen, D. et al. Clinical trials of Shigella vaccines in Israel. Adv. Exp. Med. Biol. 397, 159-167 (1996).
    • (1996) Adv. Exp. Med. Biol. , vol.397 , pp. 159-167
    • Cohen, D.1
  • 130
    • 0025786609 scopus 로고
    • Preparation, characterization, and immunogenicity of conjugates composed of the O-specific polysaccharide of Shigella dysenteriae type 1 (Shiga's bacillus) bound to tetanus toxoid
    • Chu, C. Y. et al. Preparation, characterization, and immunogenicity of conjugates composed of the O-specific polysaccharide of Shigella dysenteriae type 1 (Shiga's bacillus) bound to tetanus toxoid. Infect. Immun. 59, 4450-4458 (1991).
    • (1991) Infect. Immun. , vol.59 , pp. 4450-4458
    • Chu, C.Y.1
  • 131
    • 79951970197 scopus 로고    scopus 로고
    • Effects of backbone substitutions on the conformational behavior of Shigella flexneri O-antigens: Implications for vaccine strategy
    • Theillet, F. X. et al. Effects of backbone substitutions on the conformational behavior of Shigella flexneri O-antigens: implications for vaccine strategy. Glycobiology 21, 109-121 (2011).
    • (2011) Glycobiology , vol.21 , pp. 109-121
    • Theillet, F.X.1
  • 132
    • 78649233878 scopus 로고    scopus 로고
    • Intestinal dendritic cells: Their role in bacterial recognition, lymphocyte homing, and intestinal inflammation
    • Ng, S. C., Kamm, M. A., Stagg, A. J. & Knight, S. C. Intestinal dendritic cells: their role in bacterial recognition, lymphocyte homing, and intestinal inflammation. Inflamm. Bowel Dis. 16, 1787-1807 (2010).
    • (2010) Inflamm. Bowel Dis. , vol.16 , pp. 1787-1807
    • Ng, S.C.1    Kamm, M.A.2    Stagg, A.J.3    Knight, S.C.4


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