Phase I evaluation of ΔvirG Shigella sonnei live, attenuated, oral vaccine strain WRSS1 in healthy adults

Infection and Immunity

Volumn 70, Issue 4, 2002, Pages 2016-2021

  Kotloff, Karen L ^a   Taylor, David N ^a   Sztein, Marcelo B ^a   Wasserman, Steven S ^a   Losonsky, Genevieve A ^a   Nataro, James P ^a   Venkatesan, Malabi ^a   Hartman, Antoinette ^a   Picking, William D ^a   Katz, David E ^a   Campbell, James D ^a   Levine, Myron M ^a   Hale, Thomas L ^a  

^a University of Maryland School of Medicine Center for Vaccine Development   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIVE VACCINE; PLACEBO; SHIGELLA VACCINE; UNCLASSIFIED DRUG; WRSS1; WRSS1 VACCINE;

ADULT; ANOREXIA; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTHRALGIA; ARTICLE; CELL SECRETION; CLINICAL TRIAL; COLONY FORMING UNIT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIARRHEA; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG TOLERABILITY; FECES ANALYSIS; FEVER; GEOMETRY; HEADACHE; HUMAN; HUMAN EXPERIMENT; IMMUNOGENICITY; MALAISE; MUSCLE CRAMP; NORMAL HUMAN; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SHIGELLA SONNEI; THORAX PAIN; VACCINATION; VACCINE PRODUCTION;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; ANTIBODIES, BACTERIAL; DOUBLE-BLIND METHOD; HUMANS; IMMUNOGLOBULIN A; INTERFERON TYPE II; LACTOFERRIN; LIPOPOLYSACCHARIDES; MIDDLE AGED; SHIGELLA SONNEI; SHIGELLA VACCINES; VACCINES, ATTENUATED;

EID: 0036128648     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.70.4.2016-2021.2002     Document Type: Article

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