The Case-Only Test for Gene-Environment Interaction is Not Uniformly Powerful: An Empirical Example

Genetic Epidemiology

Volumn 37, Issue 4, 2013, Pages 402-407

  Wu, Chen ^a,b   Chang, Jiang ^b   Ma, Baoshan ^a   Miao, Xiaoping ^c   Zhou, Yifeng ^d   Liu, Yu ^b   Li, Yun ^e   Wu, Tangchun ^c   Hu, Zhibin ^f   Shen, Hongbing ^f   Jia, Weihua ^g   Zeng, Yixin ^g   Lin, Dongxin ^b   Kraft, Peter ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b CANCER HOSPITAL   (China)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^d MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

^e UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^f NANJING MEDICAL UNIVERSITY   (China)

^g SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

Author keywords

Alcohol drinking; Case only test; Esophageal squamous cell carcinoma; Gene environment interaction; SNP

Indexed keywords

ALCOHOL METABOLISM; ARTICLE; CASE ONLY TEST; DRINKING BEHAVIOR; ERROR; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; GENE LOCUS; GENETIC ASSOCIATION; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL ANALYSIS;

BAYES THEOREM; CARCINOMA, SQUAMOUS CELL; CHINA; CHROMOSOMES, HUMAN, PAIR 12; CHROMOSOMES, HUMAN, PAIR 4; ENVIRONMENT; ESOPHAGEAL NEOPLASMS; FEMALE; GENE-ENVIRONMENT INTERACTION; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALE; MODELS, GENETIC; MODELS, STATISTICAL; POLYMORPHISM, SINGLE NUCLEOTIDE; QUESTIONNAIRES; REGRESSION ANALYSIS;

EID: 84876412301     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.21713     Document Type: Article

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