Cytotoxic effect of leaf essential oil of Lippia gracilis Schauer (Verbenaceae)

Phytomedicine

Volumn 20, Issue 7, 2013, Pages 615-621

  Ferraz, Rosana P C ^a   Bomfim, Diogo S ^a   Carvalho, Nanashara C ^b   Soares, Milena B P ^b,c   Da Silva, Thanany B ^a   Machado, Wedna J ^a   Prata, Ana Paula N ^a   Costa, Emmanoel V ^a   Moraes, Valéria Regina S ^a   Nogueira, Paulo Cesar L ^a   Bezerra, Daniel P ^a  

^a FEDERAL UNIVERSITY OF SERGIPE   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c HOSPITAL SÃO RAFAEL   (Brazil)

Author keywords

Antitumor; Apoptosis; Cytotoxicity; Essential oil; Lippia gracilis

Indexed keywords

3 CARENE; 3 METHYL 3 BUTEN 1 OL ACETATE; ALPHA PHELLANDRENE; ALPHA THUJENE; AROMADENDRENE; BETA PINENE; BICYCLOGERMACRENE; CARVACROL; CARYOPHYLLENE; CINNAMIC ACID METHYL ESTER; CIS SABINENE HYDRATE; COPAENE; CYCLOSATIVENE; DOXORUBICIN; ESSENTIAL OIL; HUMULENE; LIMONENE; LINALOOL; MYRCENE; OCIMENE; PARA CYMENE; PINENE; TERPINEN 4 OL; TERPINENE; TERPINOLENE; THYMOL; THYMOL ACETATE; THYMOL METHYL ETHER; UMBELLULONE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL MEMBRANE; CELL PROLIFERATION; CELL STRAIN HEPG2; CELL STRUCTURE; CHEMICAL COMPOSITION; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; DRUG MECHANISM; HUMAN; HUMAN CELL; HYDRODISTILLATION; IN VIVO STUDY; LIPPIA; LIPPIA GRACILIS; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; PLANT LEAF; PRIORITY JOURNAL; SARCOMA 180; TUMOR CELL LINE;

ALKENES; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BRAZIL; CELL LINE, TUMOR; CELL MEMBRANE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HEP G2 CELLS; HUMANS; LIPPIA; MALE; MICE; MONOTERPENES; OILS, VOLATILE; PLANT LEAVES; PLANT OILS; PLANTS, MEDICINAL; THYMOL; XENOGRAFT MODEL ANTITUMOR ASSAYS;

LIPPIA; MUS; VERBENACEAE;

EID: 84876411421     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.01.015     Document Type: Article

References (24)

1. R.P. Adams Identification of Essential Oil Components by Gas Chromatography/Mass Spectrometry fourth ed. 2007 Allured Publishing Corporation IL
2. U.P. Albuquerque, P.M. Medeiros, A.L.S. Almeida, J.M. Monteiro, E.M.F. Lins Neto, J.G. Melo, and J.P. Santos Medicinal plants of the caatinga (semi-arid) vegetation of NE Brazil: a quantitative approach Journal of Ethnopharmacology 114 2007 325 354
3. F. Bakkali, S. Averbeck, D. Averbeck, and M. Idaomar Biological effects of essential oils: a review Food and Chemical Toxicology 46 2008 446 475
4. D.P. Bezerra, C. Pessoa, M.O. Moraes, N.M. Alencar, R.O. Mesquita, M.W. Lima, A.P. Alves, O.D. Pessoa, J.H. Chaves, E.R. Silveira, and L.V. Costa-Lotufo In vivo growth inhibition of sarcoma 180 by piperlonguminine, an alkaloid amide from the Piper species Journal of Applied Toxicology 28 2008 599 607
5. A.C.S. Britto, A.C.A. Oliveira, R.M. Henriques, G.M.B. Cardoso, D.S. Bomfim, A.A. Carvalho, M.O. Moraes, C. Pessoa, M.L.B. Pinheiro, E.V. Costa, and D.P. Bezerra In vitro and in vivo antitumor effects of the essential oil from the leaves of Guatteria friesiana Planta Medica 78 2012 409 414
6. M.G. Brown, and H.J. Lawce Peripheral blood cytogenetic methods M.J. Barch, T. Knutsen, J.L. Spurbeck, The AGT Cytogenetics Laboratory Manual 1997 Lippincott-Raven Publishers Philadelphia 77 171
7. D.D. Deb, G. Parimala, Saravana, S. Devi, and T. Chakraborty Effect of thymol on peripheral blood mononuclear cell PBMC and acute promyelotic cancer cell line HL-60 Chemico-Biological Interactions 193 2011 97 106
8. P.M. Döll-Boscardin, A. Sartoratto, B.H. Maia, J.P. Paula, T. Nakashima, P.V. Farago, and C.C. Kanunfre In vitro cytotoxic potential of essential oils of Eucalyptus benthamii and its related terpenes on tumor cell lines Evidence-Based Complementary and Alternative Medicine 2012 342652
9. M. Griffiths, and H. Sundaram Drug design and testing: profiling of antiproliferative agents for cancer therapy using a cell-based methyl-[3H]-thymidine incorporation assay Methods in Molecular Biology 731 2011 451 465
10. A.G. Guimarães, S.V. Gomes, V.R. Moraes, P.C. Nogueira, A.G. Ferreira, A.F. Blank, A.D. Santos, M.D. Viana, G.H. Silva, Quintans, and L.J. Júnior Phytochemical characterization and antinociceptive effect of Lippia gracilis Schauer Journal of Natural Medicines 66 2012 428 434
11. H. Lorenzi, and F.J.A. Matos Plantas Medicinais no Brasil: Nativas e Exóticas second ed. 2008 Instituto Plantarum Nova Odessa
12. S.S. Mendes, R.R. Bomfim, H.C. Jesus, P.B. Alves, A.F. Blank, C.S. Estevam, A.R. Antoniolli, and S.M. Thomazzi Evaluation of the analgesic and anti-inflammatory effects of the essential oil of Lippia gracilis leaves Journal of Ethnopharmacology 129 2010 391 397
13. S.A. Mori, L.A.M. Silva, G. Lisboa, and L. Coradin Manual de manejo do herbário fanerogâmico second ed. 1989 CEPLAC Ilhéus
14. I.A. Neves, J.C.S. de Oliveira, C.A.G. da Camara, and M.O.E. Schwartz Chemical composition of the leaf oils of Lippia gracilis Schauer from two localities of Pernambuco Journal of Essential Oil Research 20 2008 157 160
15. M.E. Pascual, K. Slowing, E. Carretero, D. Sánchez Mata, and A. Villar Lippia: traditional uses, chemistry and pharmacology: a review Journal of Ethnopharmacology 76 2001 201 214
16. O.D. Pessoa, C.B. de Carvalho, J.O. Silvestre, M.C. Lima, R.M. Neto, F.J. Matos, and T.L. Lemos Antibacterial activity of the essential oil from Lippia aff. gracilis Fitoterapia 76 2005 712 714
17. B. Pucci, M. Kasten, and A. Giordano Cell cycle and apoptosis Neoplasia 2 2000 291 299
18. S.S. Ribeiro, A.M. Jesus, C.S. Anjos, T.B. Silva, A.D.C. Santos, J.R. Jesus, M.S. Andrade, T.S. Sampaio, W.F. Gomes, P.B. Alves, A.A. Carvalho, C. Pessoa, M.O. Moraes, M.L.B. Pinheiro, A.P.N. Prata, A.F. Blank, R. Silva-Mann, V.R.S. Moraes, E.V. Costa, P.C.L. Nogueira, and D.P. Bezerra Evaluation of the cytotoxic activity of some Brazilian medicinal plants Planta Medica 78 2012 1601 1606
19. W.J. Silva, G.A. Dória, R.T. Maia, R.S. Nunes, G.A. Carvalho, A.F. Blank, P.B. Alves, R.M. Marçal, and S.C. Cavalcanti Effects of essential oils on Aedes aegypti larvae: alternatives to environmentally safe insecticides Bioresource Technology 99 2008 3251 3255
20. M. Suffness, and J.M. Pezzuto Assays related to cancer drug discovery K. Hostettmann, Methods in Plant Biochemistry: Assays for Bioactivity 1990 Academic Press London 71 133
21. T.V. Teles, R.R. Bonfim, P.B. Alves, A.F. Blank, H.C.R. Jesus, L.J. Quintans Jr., M.R. Serafini, L.R. Bonjardim, and A.A.S. Araújo Composition and evaluation of the lethality of Lippia gracilis essential oil to adults of Biomphalaria glabrata and larvae of Artemia salina African Journal of Biotechnology 9 2010 8800 8804
22. K.V. Tret'yakov Retention data P.J. Linstrom, W.G. Mallard, NIST Chemistry Webbok 2008 National Institute of Standards and Technology Gaithersburg, MD NIST Standard Reference Database Number 69, http://webbook.nist.gov/chemistry/ (accessed September, 2012)
23. H. van Den Dool, and P.D. Kratz A generalization of the retention index system including linear temperature programmed gas-liquid partition chromatography Journal of Chromatography 11 1963 463 471
24. C.M. Walsh, and A.L. Edinger The complex interplay between autophagy, apoptosis, and necrotic signals promotes T-cell homeostasis Immunological Reviews 236 2010 95 109