Novel effects of ectoine, a bacteria-derived natural tetrahydropyrimidine, in experimental colitis

Phytomedicine

Volumn 20, Issue 7, 2013, Pages 585-591

  Abdel Aziz, Heba ^a   Wadie, Walaa ^b   Abdallah, Dalaal M ^b   Lentzen, Georg ^c   Khayyal, Mohamed T ^b  

^a HELIOPOLIS UNIVERSITY   (Egypt)

^b CAIRO UNIVERSITY   (Egypt)

^c BITOP AG   (Germany)

Author keywords

Compatible solutes; Ectoines; Inflammatory bowel disease; Intestinal barrier; Trinitrobenzenesulfonic acid

Indexed keywords

ECTOINE; GLUTATHIONE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; LEUKOTRIENE B4; MALONALDEHYDE; MYELOPEROXIDASE; PROSTAGLANDIN E2; SALAZOSULFAPYRIDINE; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; COLITIS; CONTROLLED STUDY; DRUG MECHANISM; HISTOPATHOLOGY; HOMOGENATE; INFLAMMATION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

AMINO ACIDS, DIAMINO; ANIMALS; BODY WEIGHT; COLITIS; COLON; DINOPROSTONE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1BETA; LEUKOTRIENE B4; MALE; MALONDIALDEHYDE; RATS; RATS, WISTAR; SULFASALAZINE; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; RATTUS;

EID: 84876406668     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.01.009     Document Type: Article

References (51)

1. T. Arakawa, and S.N. Timasheff The stabilization of proteins by osmolytes Archives of Biochemistry and Biophysics 224 1985 169 177
2. E. Beutler, O. Duron, and B.M. Kelly Improved method for the determination of blood glutathione Journal of Laboratory and Clinical Medicine 61 1963 882 888
3. L. Bhaskar, B.S. Ramakrishna, and K.A. Balasubramanian Colonic mucosal antioxidant enzymes and lipid peroxide levels in normal subjects and patients with ulcerative colitis Journal of Gastroenterology and Hepatology 10 1995 140 143
4. J. Bünger, and H. Driller Ectoin: an effective natural substance to prevent UVA-induced premature photoaging Skin Pharmacology and Physiology 17 2004 232 237
5. E. Buommino, C. Schiraldi, A. Baroni, I. Paoletti, M. Lamberti, M. De Rosa, and M.A. Tufano Ectoine from halophilic microorganisms induces the expression of hsp70 and hsp70B′ in human keratinocytes modulating the proinflammatory response Cell Stress and Chaperones 10 2005 197 203
6. E. Carty, and D.S. Rampton Evaluation of new therapies for inflammatory bowel disease British Journal of Clinical Pharmacology 56 2003 351 361
7. K.D. Collins, and M.W. Washabaugh The Hofmeister effect and the behaviour of water at interfaces Quarterly Reviews of Biophysics 18 1985 323 422
8. S. Cuzzocrea, A. Ianaro, N.S. Wayman, E. Mazzon, B. Pisano, L. Dugo, I. Serraino, R. Di Paola, P.K. Chatterjee, M. Di Rosa, A.P. Caputi, and C. Thiemermann The cyclopentenone prostaglandin 15-deoxy-delta(12,14)- PGJ2 attenuates the development of colon injury caused by dinitrobenzene sulphonic acid in the rat British Journal of Pharmacology 138 2003 678 688
9. S. Danese, C. de la Motte, A. Sturm, J.D. Vogel, G.A. West, S.A. Strong, J.A. Katz, and C. Fiocchi Platelets trigger a CD40-dependent inflammatory response in the microvasculature of inflammatory bowel disease patients Gastroenterology 124 2003 1249 1264
10. I. Dotan, and L. Mayer Immunopathogensis of inflammatory bowel disease Current Opinion in Gastroenterology 18 2002 421 427
11. E.A. Galinski Compatible solutes of halophilic eubacteria: molecular principles, water-solute interaction, stress protection Cellular and Molecular Life Sciences 49 1993 487 496
12. M. Goke, J.C. Hoffmann, J. Evers, H. Krüger, and M.P. Manns Elevated serum concentrations of soluble selectin and immunoglobulin type adhesion molecules in patients with inflammatory bowel disease Journal of Gastroenterology 32 1997 480 486
13. M.B. Grisham, and T. Yamada Neutrophils, nitrogen oxides and inflammatory bowel disease Annals of the New York Academy of Sciences 664 1992 103 115
14. S. Hanauer Inflammatory bowel disease: epidemiology, pathogenesis and therapeutic opportunities Inflammatory Bowel Diseases 12 2006 S3 S9
15. R.K. Harishchandra, S. Wulff, G. Lentzen, T. Neuhaus, and H.J. Galla The effect of compatible solute ectoines on the structural organization of lipid monolayer and bilayer membranes Biophysical Chemistry 150 2010 37 46
16. S. Horowitz, D.G. Binion, V.M. Nelson, Y. Kanaa, P. Javadi, Z. Lazarova, C. Andrekopoulos, B. Kalyanaraman, M.F. Otterson, and P. Rafiee Increased arginase activity and endothelial dysfunction in human inflammatory bowel disease American Journal of Physiology Gastrointestinal and Liver Physiology 292 2007 G1323 G1336
17. R. Kiesslich, C.A. Duckworth, D. Moussata, A. Gloeckner, L.G. Lim, M. Goetz, D.M. Pritchard, P.R. Galle, M.F. Neurath, and A.J. Watson Local barrier dysfunction identified by confocal laser endomicroscopy predicts relapse in inflammatory bowel disease Gut 61 2012 1146 1153
18. G. Kolios, C. Petoumenos, and A. Nakos Mediators of inflammation: production and implication in inflammatory bowel disease Hepato-Gastroenterology 45 1998 1601 1609
19. J.E. Krawisz, P. Sharon, and W.F. Stenson Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models Gastroenterology 87 1984 1344 1350
20. F.L. Lanza, R.L. Kochman, G.S. Geis, E.M. Rack, and L.G. Deysach A double-blind, placebo-controlled, 6-day evaluation of two doses of misoprostol in gastroduodenal mucosal protection against damage from aspirin and effect on bowel habits American Journal of Gastroenterology 86 1991 1743 1748
21. K. Lippert, and E.A. Galinski Enzyme stabilization by ectoine-type compatible solutes: protection against heating, freezing and drying Applied Microbiology and Biotechnology 37 1992 61 65
22. A.M. Marchiando, W.V. Graham, and J.R. Turner Epithelial barriers in homeostasis and disease Annual Review of Pathology 5 2010 119 144
23. G.R. May, L.R. Sutherland, and J.B. Meddings Is small intestinal permeability really increased in relatives of patients with Crohn's disease? Gastroenterology 104 1993 1627 1632
24. J. Meddings The significance of the gut barrier in disease Gut 57 2008 438 440
25. G.Y. Melmed, and M.T. Abreu New insights into the pathogenesis of inflammatory bowel disease Current Gastroenterology Reports 6 2004 474 481
26. S.J. Middleton, M. Shorthouse, and J.O. Hunter Increased nitric oxide synthesis in ulcerative colitis Lancet 341 1993 465 466
27. M. Mihara, and M. Uchiyama Determination of malonaldehyde precursor in tissues by thiobarbituric acid test Analytical Biochemistry 86 1978 271 278
28. K.M. Miranda, M.G. Espey, and D.A. Wink A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite Nitric Oxide 5 2001 62 71
29. G.P. Morris, P.L. Beck, M.S. Herridge, W.T. Depew, M.R. Szewczuk, and J.L. Wallace Hapten-induced model of chronic inflammation and ulceration in the rat colon Gastroenterology 96 1989 795 803
30. R.D. Newberry, W.F. Stenson, and R.G. Lorenz Cyclooxygenase-2-dependent arachidonic acid metabolites are essential modulators of the intestinal immune response to dietary antigen Nature Medicine 8 1999 900 906
31. O.H. Nielsen, E. Langholz, J. Hendel, and J. Brynskov Circulating soluble intercellular adhesion molecule-1 (sICAM-1) in active inflammatory bowel disease Digestive Diseases and Sciences 39 1994 1918 1923
32. O.H. Nielsen, and J. Rask-Madsen Mediators of inflammation in chronic inflammatory bowel disease Scandinavian Journal of Gastroenterology. Supplement 216 1996 149 159
33. J.M. Pastor, M. Salvador, M. Argandoña, V. Bernal, M. Reina-Bueno, L.N. Csonka, J.L. Iborra, C. Vargas, J.J. Nieto, and M. Cánovas Ectoines in cell stress protection: uses and biotechnological production Biotechnology Advances 28 2010 782 801
34. M. Peeters, Y. Ghoos, B. Maes, M. Hiele, K. Geboes, G. Vantrappen, and P. Rutgeerts Increased permeability of macroscopically normal small bowel in Crohn's disease Digestive Diseases and Sciences 39 1994 2170 2176
35. M. Peeters, B. Geypens, D. Claus, H. Nevens, Y. Ghoos, G. Verbeke, F. Baert, S. Vermeire, R. Vlietinck, and P. Rutgeerts Clustering of increased small intestinal permeability in families with Crohn's disease Gastroenterology 113 1997 802 807
36. H. Peuschel, U. Sydlik, J. Haendeler, N. Büchner, D. Stöckmann, M. Kroker, R. Wirth, W. Brock, and K. Unfried c-Src-mediated activation of Erk1/2 is a reaction of epithelial cells to carbon nanoparticle treatment and may be a target for a molecular preventive strategy Biological Chemistry 391 2010 1327 1332
37. C.J. Pfeiffer, and B.S. Qiu Effects of chronic nitric oxide synthase inhibition on TNB-induced colitis in rats Journal of Pharmacy and Pharmacology 47 1995 827 832
38. K.A. Ribbons, X.J. Zhang, J.H. Thompson, S.S. Greenberg, W.M. Moore, C.M. Kornmeier, M.G. Currie, N. Lerche, J. Blanchard, D.A. Clark, and M.J.S. Miller Potential role of nitric oxide in a model of chronic colitis in rhesus macaques Gastroenterology 108 1995 705 711
39. A. Roychoudhury, D. Haussinger, and F. Oesterhelt Effect of the compatible solute ectoine on the stability of the membrane proteins Protein & Peptide Letters 19 2012 791 794
40. S. Sánchez-Fidalgo, I. Villegas, A. Martín, M. Sánchez-Hidalgo, and C. Alarcón de la Lastra PARP inhibition reduces acute colonic inflammation in rats European Journal of Pharmacology 563 2007 216 223
41. R.B. Sartor Pathogenesis and immune mechanisms of chronic inflammatory bowel diseases American Journal of Gastroenterology 92 1997 5S 11S
42. S.Y. Shaw, J.F. Blanchard, and C.N. Bernstein Association between the use of antibiotics and new diagnoses of Crohn's disease and Ulcerative colitis American Journal of Gastroenterology 106 2011 2133 2142
43. B. Siegmund Interleukin-1beta converting enzyme (caspase-1) in intestinal inflammation Biochemical Pharmacology 64 2002 1 8
44. A. Stallmach, T. Giese, C. Schmidt, B. Ludwig, I. Mueller-Molaian, and S.C. Meuer Cytokine/chemokine transcript profiles reflect mucosal inflammation in Crohn's disease International Journal of Colorectal Disease 19 2004 308 315
45. U. Sydlik, I. Gallitz, C. Albrecht, J. Abel, J. Krutmann, and K. Unfried The compatible solute ectoine protects against nanoparticle-induced neutrophilic lung inflammation American Journal of Respiratory and Critical Care Medicine 180 2009 29 35
46. U. Sydlik, H. Peuschel, A. Paunel-Görgülü, S. Keymel, U. Krämer, A. Weissenberg, M. Kroker, S. Seghrouchni, C. Heiss, J. Windolf, A. Bilstein, M. Kelm, J. Krutmann, and K. Unfried Recovery of neutrophil apoptosis by ectoine: a new strategy against lung inflammation European Respiratory Journal 2012 10.1183/09031936.00132211
47. A. Tüzün, A. Erdil, V. Inal, A. Aydin, S. Baǧci, Z. Yeşilova, A. Sayal, N. Karaeren, and K. Daǧalp Oxidative stress and antioxidant capacity in patients with inflammatory bowel disease Clinical Biochemistry 35 2002 569 572
48. W.P. Wang, X. Guo, M.W. Koo, B.C. Wong, S.K. Lam, Y.N. Ye, and C.H. Cho Protective role of heme oxygenase-1 on trinitrobenzene sulfonic acid-induced colitis in rats American Journal of Physiology Gastrointestinal and Liver Physiology 281 2001 G586 G594
49. L. Wei, A. Wedeking, R. Buttner, J.C. Kalff, R.H. Tolba, and G. van Echten-Deckert A natural tetrahydropyrimidine protects small bowel from cold ischemia and subsequent warm in vitro reperfusion injury Pathobiology 76 2009 212 220
50. J. Wyatt, H. Vogelsang, W. Hübl, T. Waldhöer, and H. Lochs Intestinal permeability and the prediction of relapse in Crohn's disease Lancet 341 1993 1437 1439
51. I. Yu, Y. Jindo, and M. Nagaoka Microscopic understanding of preferential exclusion of compatible solute ectoine: direct interaction and hydration alteration Journal of Physical Chemistry B 111 2007 10231 10238