Identification of nuclear factor-κB sites in the Slc2a4 gene promoter

Molecular and Cellular Endocrinology

Volumn 370, Issue 1-2, 2013, Pages 87-95

  Furuya, D T ^a   Neri, E A ^a   Poletto, A C ^a   Anhe G F ^b   Freitas, H S ^a   Campello, R S ^a   Reboucas N A ^a   Machado, U F ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Gene reporter; GLUT4; Inflammation; Insulin resistance; NF B; Slc2a4

Indexed keywords

GENOMIC DNA; GLUCOSE TRANSPORTER 4; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P50; TRANSCRIPTION FACTOR RELA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA FLANKING REGION; ELECTROPHORETIC MOBILITY; GLUCOSE TRANSPORTER 4 GENE; INSULIN RESISTANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; RAT; REPRESSOR GENE; SEQUENCE ANALYSIS; TRANSCRIPTION INITIATION;

3T3 CELLS; ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; DNA-BINDING PROTEINS; GLUCOSE TRANSPORTER TYPE 4; INFLAMMATION; INSULIN RESISTANCE; MICE; NF-KAPPA B; NF-KAPPA B P50 SUBUNIT; OBESITY; PROMOTER REGIONS, GENETIC; RATS; SEQUENCE ANALYSIS, DNA; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION, GENETIC;

EID: 84876402852     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2013.01.019     Document Type: Article

References (21)

1. Andrews N.C., Faller D.V. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucl. Acids Res. 1991, 19:2499.
2. Armoni M., Harel C., Bar-Yoseph F., Milo S., Karnieli E. Free fatty acids repress the GLUT4 gene expression in cardiac muscle via novel response elements. J. Biol. Chem. 2005, 280:34786-34795.
3. Balasubramanian S., Fan M., Messmer-Blust A.F., Yang C.H., Trendel J.A., Jeyaratnam J.A., Pfeffer L.M., Vestal D.J. The Interferon-γ-induced GTPase, mGBP-2, inhibits tumor necrosis factor α (TNF-α) induction of matrix metalloproteinase-9 (MMP-9) by inhibiting NF-411 κB and Rac protein. J. Biol. Chem. 2011, 286:20054-20064.
4. Cancello R., Henegar C., Viguerie N., Taleb S., Poitou C., Rouault C., Coupaye M., Pelloux V., Hugol D., Bouillot J.L., Bouloumié A., Barbatelli G., Cinti S., Svensson P.A., Barsh G.S., Zucker J.D., Basdevant A., Langin D., Clément K. Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss. Diabetes 2005, 54:2277-2286.
5. Ezaki O. Regulatory elements in the insulin-responsive glucose transporter (GLUT4) gene. Biochem. Biophys. Res. Commun. 1997, 241:1-6.
6. Freitas H.S., Schaan B.D., David-Silva A., Sabino-Silva R., Okamoto M.M., Alves-Wagner A.B., Mori R.C., Machado U.F. SLC2A2 gene expression in kidney of diabetic rats is regulated by HNF-1alpha and HNF-3 beta. Mol. Cell. Endocrinol. 2009, 305:63-70.
7. Furuya D.T., Poletto A.C., Favaro R.R., Martins J.O., Zorn T.M., Machado U.F. Anti-inflammatory effect of atorvastatin ameliorates insulin resistance in monosodium glutamate-treated obese mice. Metabolism 2010, 59:395-399.
8. Gilmore T.D. Introduction to NF-kappaB: players, pathways, perspectives. Oncogene 2006, 25:6680-6684.
9. Hoffmann A., Natoli G., Ghosh G. Transcriptional regulation via the NF-kappaB signaling module. Oncogene 2006, 25:6706-6716.
10. Juarranz Y., Abad C., Martinez C., Arranz A., Gutierrez-Cañas I., Rosignoli F., Gomariz R.P., Leceta J. Protective effect of vasoactive intestinal peptide on bone destruction in the collagen-induced arthritis model of rheumatoid arthritis. Arthritis Res. Ther. 2005, 7:1034-1045.
11. Kahn B.B. Lilly lecture 1995. Glucose transport: pivotal step in insulin action. Diabetes 1996, 45:1644-1654.
12. Kretz-Remy C., Mehlen P., Mirault M.E., Arrigo A.P. Inhibition of I kappa B-alpha phosphorylation and degradation and subsequent NF-kappa B activation by glutathione peroxidase overexpression. J. Cell Biol. 1996, 133:1083-1093.
13. Lima G.A., Anhê G.F., Giannocco G., Nunes M.T., Correa-Giannella M.L., Machado U.F. Contractile activity per se induces transcriptional activation of Slc2a4 gene in soleus muscle: involvement of MEF2D, HIF-1a, and TRα transcriptional factors. Am. J. Physiol. Endocrinol. Metab. 2009, 296:132-138.
14. Lin L. RAGE on the toll road?. Cell Mol. Immunol. 2006, 3:351-358.
15. Liu A., Hoffman P.W., Lu W., Bai G. NF-kappaB site interacts with Sp factors and up-regulates the NR1 promoter during neuronal differentiation. J. Biol. Chem. 2004, 279:17449-17458.
16. Papa P.C., Seraphim P.M., Machado U.F. Loss of weight restores GLUT 4 content in insulin-sensitive tissues of monosodium glutamate-treated obese mice. Int. J. Obes. Relat. Metab. Disord. 1997, 21:1065-1070.
17. Ruan H., Hacohen N., Golub T.R., Van Parijs L., Lodish H.F. Tumor necrosis factor-alpha suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: nuclear factor-kappaB activation by TNF-alpha is obligatory. Diabetes 2002, 51:1319-1336.
18. Silva J.L., Giannocco G., Furuya D.T., Lima G.A., Moraes P.A., Nachef S., Bordin S., Britto L.R., Nunes M.T., Machado U.F. NF-kappaB, MEF2A, MEF2D and HIF1-a involvement on insulin- and contraction-induced regulation of GLUT4 gene expression in soleus muscle. Mol. Cell. Endocrinol. 2005, 240:83-93.
19. Stephens J.M., Pekala P.H. Transcriptional repression of the GLUT4 and C/EBP genes in 3T3-L1 adipocytes by tumor necrosis factor-alpha. J. Biol. Chem. 1991, 266:21839-21845.
20. Stephens J.M., Lee J., Pilch P.F. Tumor necrosis factor-alpha-induced insulin resistance in 3T3-L1 adipocytes is accompanied by a loss of insulin receptor substrate-1 and GLUT4 expression without a loss of insulin receptor-mediated signal transduction. J. Biol. Chem. 1997, 272:971-976.
21. Urban M.B., Baeuerle P.A. The p50 and p65 subunits of NFkappa B in the recognition of cognate sequences. New Biol. 1991, 3:279-288.