Loss of weight restores GLUT 4 content in insulin-sensitive tissues of monosodium glutamate-treated obese mice

International Journal of Obesity

Volumn 21, Issue 11, 1997, Pages 1065-1070

  Papa, P C ^a   Seraphim, P M ^a   Machado, U F ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Glucose transporters; GLUT 4; Monosodium glutamate; Obesity insulin resistance

Indexed keywords

GLUCOSE; GLUCOSE TRANSPORTER; GLUTAMATE SODIUM; INSULIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTHROPOMETRY; ARTICLE; BROWN ADIPOSE TISSUE; CALORIC RESTRICTION; CONTROLLED STUDY; FEMALE; GLUCOSE BLOOD LEVEL; HEART MUSCLE; HYPERGLYCEMIA; HYPERINSULINEMIA; IMMUNOBLOTTING; INSULIN SENSITIVITY; INSULINEMIA; MALE; MEMBRANE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN CONTENT; SKELETAL MUSCLE; WEIGHT REDUCTION; WHITE ADIPOSE TISSUE;

ANIMALIA;

EID: 0030819204     PISSN: 03070565     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ijo.0800517     Document Type: Article

References (30)

1. Reaven GM. Role of insulin resistance in human disease. Diabetes 1988; 37: 1595-1607.
2. DeFronzo RA, Ferranini EF. Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 1991; 14: 173-194.
3. Bell GI, Kaynao T, Buse JB, Burant CF, Takeda J, Lin D, Fukumoto H, Seino S. Molecular biology of mammalian glucose transporters. Diabetes Care 1990; 13: 198-208.
4. Carruthers A. Facilitated diffusion of glucose. Physiol Rev 1990; 70: 1135-1173.
5. Thorens B, Charron MJ, Lodish HF. Molecular physiology of glucose transporters. Diabetes Care 1990; 13: 209-218.
6. Kahn BB, Charron MJ, Lodish HF, Cushman SW, Flier JS. Differential regulation of two glucose transporters in adipose cells from diabetic and insulin-treated diabetic rats. J Clin Invest 1989; 84: 404-411.
7. Karnieli E, Armoni M. Regulation of glucose transporters in diabetes. Horm Res 1990; 33: 99-104.
8. Sinha MK, Raineri-Maldonado C, Buchanan C, Pories WJ, Carter-Su C, Pilch PF, Caro JF. Adipose tissue glucose transporters in NIDDM - Decreased levels of muscle/fat isoform. Diabetes 1991; 40: 472-477.
9. Garvey WT. Glucose transport and NIDDM. Diabetes Care 1992; 15: 396-417.
10. Cusin I, Terrettaz J, Rohner-Jeanrenaud F, Zarjevski N, Assimacopoulos-Jeannet F, Jeanrenaud B. Hyperinsulinemia increases the amount of GLUT 4 mRNA in white adipose tissue and decreases that of muscles: a clue for increased fat depot and insulin resistance. Endocrinology 1990; 127: 3246-3248.
11. Berger J, Biswas C, Vicario PP, Strout HV, Saperstein R, Pilch PF. Decreased expression of the insulin-responsive glucose transporter in diabetes and fasting. Nature 1989; 340: 70-72.
12. Sivitz WI, DeSautel SL, Kayano T, Bell GI, Pessin JE. Regulation of glucose transporter messenger RNA in insulin-deficient states. Nature 1989; 340: 72-74.
13. Kahn BB, Cushman SW, Flier JS. Regulation of glucose transporter-specific mRNA levels in rat adipose cells with fasting and refeeding. J Clin Invest 1989; 83: 199-204.
14. Le Marchand-Brustel Y, Olichon-Berthe C, Grémeaux T, Tanti J-F, Rochet N, Van Obberghen E. Glucose transporter in insulin sensitive tissues of lean and obese mice. Effect of the thermogenic agent BRL 26830A. Endocrinology 1990; 127: 2687-2695.
15. Ezaki O, Fukuda N, Itakura H. Role of two types of glucose transporters in enlarged adipocytes from aged obese rats. Diabetes 1990; 39: 1543-1549.
16. Seino Y, Yamamoto T, Koh G. Insulin and glucose transporter gene expression in obesity and diabetes. Proc Soc Exp Biol Med 1992; 200: 210-213.
17. Kahn BB, Pedersen O. Tissue-specific regulation of glucose transporters in different forms of obesity. Proc Soc Exp Biol Med 1992; 200: 214-217.
18. Machado UF, Shimizu Y, Saito M. Decreased glucose transporter (GLUT 4) content in insulin-sensitive tissues of obese aurothioglucose- and monosodium glutamate-treated mice. Horm Metab Res 1993; 25: 462-465.
19. Di Girolamo M, Rudman D. Variations in glucose metabolism and sensitivity to insulin of the rat's adipose tissue, in relation to age and body weight. Endocrinology 1968; 82: 1133-1141.
20. Campbell PJ, Carlson MG. Impact of obesity on insulin action in NIDDM. Diabetes 1993; 42: 405-410.
21. Cartee GD, Kietzke EW, Briggs-Tung C. Adaptation of muscle glucose transport with caloric restriction in adult, middle-aged, and old rats. Am J Physiol 1994; 266: R1443-R1447.
22. Machado UF, Saito M. Characterization of subcellular membrane fractions from white adipose tissue of obese mice. Arq Biol Tecnol 1994; 37: 139-145.
23. Ciaraldi TP, Molina JM, Olefsky JM. Insulin action kinetics in adipocytes from obese and noninsulin-dependent diabetes mellitus subjects: identification of multiple cellular defects in glucose transport. J Clin Endocrinol Metab 1991; 72: 876-882.
24. Machado UF, Shimizu Y, Saito M. Reduced content and preserved translocation of glucose transporter (GLUT 4) in white adipose tissue of obese mice. Physiol Behav 1994; 55: 621-625.
25. Caro JF. Insulin resistance in obese and nonobese man. J Clin Endocrinol Metab 1991; 73: 691-695.
26. Pénicaud L, Ferré P. Development of insulin resistance during the course of obesity: lessons from animal models. J Obesity Weight Regul 1988; 7: 91-109.
27. Pénicaud L, Kinebanyan MF, Ferré P, Morin J, Kandé J, Smadja C, Marfaing-Tallat P, Picon L. Development of VMH obesity: in vivo insulin secretion and tissue insulin sensitivity. Am J Physiol 1989; 257: E255-E260.
28. Cousin B, Agou K, Leturque A, Ferré P, Girard J, Pénicaud L. Molecular and metabolic changes in white adipose tissue of the rat during development of ventromedial hypothalamic obesity. Eur J Biochem 1992; 207: 377-382.
29. Pujol A, Cousin B, Burnol AF, Loizeau M, Picon L, Girard J, Pénicaud L. Insulin receptor kinase activity in muscles and white adipose tissue during course of VMH obesity. Am J Physiol 1992; 262: E161-E166.
30. Hainault I, Guerre-Milo M, Guichard C, Lavau M. Differential regulation of adipose tissue glucose transporters in genetic obesity (fatty rat). J Clin Invest 1991; 87: 1127-1131.