-
2
-
-
0033855736
-
Inhibitors of tyrosine kinases in the treatment of psoriasis
-
H. Ben-Bassat, and A. Levitzki Inhibitors of tyrosine kinases in the treatment of psoriasis IMAJ 2 Suppl 2000 69 73
-
(2000)
IMAJ
, Issue.2 SUPPL.
, pp. 69-73
-
-
Ben-Bassat, H.1
Levitzki, A.2
-
3
-
-
0028859279
-
Protein modules and signalling networks
-
T. Pawson Protein modules and signalling networks Nature 16 1995 573 580
-
(1995)
Nature
, vol.16
, pp. 573-580
-
-
Pawson, T.1
-
4
-
-
62849094732
-
Selectivity and therapeutic inhibition of kinases: To be or not to be?
-
K. Ghoreschi, A. Laurence, and J.J. O'Shea Selectivity and therapeutic inhibition of kinases: to be or not to be? Nat Immunol 10 2009 356 360
-
(2009)
Nat Immunol
, vol.10
, pp. 356-360
-
-
Ghoreschi, K.1
Laurence, A.2
O'Shea, J.J.3
-
5
-
-
0034131327
-
Inhibitors of tyrosine kinases in the treatment of psoriasis
-
H. Ben Bassat, and B.Y. Klein Inhibitors of tyrosine kinases in the treatment of psoriasis Curr Pharm Des 6 2000 933 942
-
(2000)
Curr Pharm des
, vol.6
, pp. 933-942
-
-
Ben Bassat, H.1
Klein, B.Y.2
-
6
-
-
0030198344
-
Protein kinase cascades activated by stress and inflammatory cytokines
-
J.M. Kyriakis, and J. Avruch Protein kinase cascades activated by stress and inflammatory cytokines Bioassays 18 1996 567 577
-
(1996)
Bioassays
, vol.18
, pp. 567-577
-
-
Kyriakis, J.M.1
Avruch, J.2
-
7
-
-
60449117455
-
Kinase inhibitors for the treatment of inflammatory and autoimmune disorders
-
S.S. Bhagwat Kinase inhibitors for the treatment of inflammatory and autoimmune disorders Purinergic Signal 5 2009 107 115
-
(2009)
Purinergic Signal
, vol.5
, pp. 107-115
-
-
Bhagwat, S.S.1
-
8
-
-
33847351136
-
The JAK-STAT signaling pathway: Input and output integration
-
P.J. Murray The JAK-STAT signaling pathway: input and output integration J Immunol 178 2007 2623 2629
-
(2007)
J Immunol
, vol.178
, pp. 2623-2629
-
-
Murray, P.J.1
-
9
-
-
67649397492
-
CP-690550 a JAK3 inhibitor as an immunosuppressant for the treatment of rheumatoid arthritis, transplant rejection, psoriasis and other immune-mediated disorders
-
K. West CP-690550 a JAK3 inhibitor as an immunosuppressant for the treatment of rheumatoid arthritis, transplant rejection, psoriasis and other immune-mediated disorders Curr Opin Investig Drugs 10 2009 491 504
-
(2009)
Curr Opin Investig Drugs
, vol.10
, pp. 491-504
-
-
West, K.1
-
10
-
-
70349736206
-
Double-blind, placebo controlled, dose-escalation study to evaluate the pharmacologic effect of CP-690,550 in patients with psoriasis
-
M.G. Boy, C. Wang, B.E. Wilkinson, V.F. Chow, A.T. Clucas, and J.G. Krueger Double-blind, placebo controlled, dose-escalation study to evaluate the pharmacologic effect of CP-690,550 in patients with psoriasis J Invest Dermatol 129 2009 2299 3029
-
(2009)
J Invest Dermatol
, vol.129
, pp. 2299-3029
-
-
Boy, M.G.1
Wang, C.2
Wilkinson, B.E.3
Chow, V.F.4
Clucas, A.T.5
Krueger, J.G.6
-
11
-
-
79953176994
-
Tasocitinib
-
Tasocitinib. Drugs R D. 2010;10:271-84.
-
(2010)
Drugs R D
, vol.10
, pp. 271-284
-
-
-
12
-
-
84861043518
-
Risk of tuberculosis reactivation with tofacitinib (CP-690550)
-
M. Maiga, S. Lun, H. Guo, K. Winglee, N.C. Ammerman, and W.R. Bishai Risk of tuberculosis reactivation with tofacitinib (CP-690550) J Infec Dis 205 2012 1705 1708
-
(2012)
J Infec Dis
, vol.205
, pp. 1705-1708
-
-
Maiga, M.1
Lun, S.2
Guo, H.3
Winglee, K.4
Ammerman, N.C.5
Bishai, W.R.6
-
13
-
-
47249157224
-
Therapeutic targeting of Janus kinases
-
M. Pesu, A. Laurence, N. Kishore, S.H. Zwillich, G. Chan, and J.J. O'Shea Therapeutic targeting of Janus kinases Immunol Rev 223 2008 132 142
-
(2008)
Immunol Rev
, vol.223
, pp. 132-142
-
-
Pesu, M.1
Laurence, A.2
Kishore, N.3
Zwillich, S.H.4
Chan, G.5
O'Shea, J.J.6
-
14
-
-
52949089050
-
JAKs in pathology: Role of Janus kinases in hematopoietic malignancies and immunodeficiencies
-
W. Vainchenker, A. Dusa, and S.N. Constantinescu JAKs in pathology: role of Janus kinases in hematopoietic malignancies and immunodeficiencies Semin Cell Dev Biol 19 2008 385 393
-
(2008)
Semin Cell Dev Biol
, vol.19
, pp. 385-393
-
-
Vainchenker, W.1
Dusa, A.2
Constantinescu, S.N.3
-
15
-
-
84864066214
-
Preliminary clinical activity of a topical JAK1/2 inhibitor in the treatment of psoriasis
-
N. Punwani, P. Scherle, R. Flores, J. Shi, J. Liang, and S. Yeleswaram Preliminary clinical activity of a topical JAK1/2 inhibitor in the treatment of psoriasis J Am Acad Dermatol 67 2012 658 664
-
(2012)
J Am Acad Dermatol
, vol.67
, pp. 658-664
-
-
Punwani, N.1
Scherle, P.2
Flores, R.3
Shi, J.4
Liang, J.5
Yeleswaram, S.6
-
16
-
-
68149182278
-
JAK3 inhibition significantly attenuates psoriasiform skin inflammation in CD18 mutant PL/J mice
-
B.Y. Chang, F. Zhao, X. He, H. Ren, S. Braselmann, and V. Taylor JAK3 inhibition significantly attenuates psoriasiform skin inflammation in CD18 mutant PL/J mice J Immunol 183 2009 2183 2192
-
(2009)
J Immunol
, vol.183
, pp. 2183-2192
-
-
Chang, B.Y.1
Zhao, F.2
He, X.3
Ren, H.4
Braselmann, S.5
Taylor, V.6
-
17
-
-
33751197936
-
R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation
-
S. Braselmann, V. Taylor, H. Zhao, S. Wang, C. Sylvain, and M. Baluom R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation J Pharmacol Exp Ther 319 2006 998 1008
-
(2006)
J Pharmacol Exp Ther
, vol.319
, pp. 998-1008
-
-
Braselmann, S.1
Taylor, V.2
Zhao, H.3
Wang, S.4
Sylvain, C.5
Baluom, M.6
-
18
-
-
77957333252
-
An oral spleen tyrosine kinase (Syk) inhibitor for rheumatoid arthritis
-
M.E. Weinblatt, A. Kavanaugh, M.C. Genovese, T.K. Musser, E.B. Grossbard, and D.B. Magilavy An oral spleen tyrosine kinase (Syk) inhibitor for rheumatoid arthritis N Engl J Med 363 2010 1303 1312
-
(2010)
N Engl J Med
, vol.363
, pp. 1303-1312
-
-
Weinblatt, M.E.1
Kavanaugh, A.2
Genovese, M.C.3
Musser, T.K.4
Grossbard, E.B.5
Magilavy, D.B.6
-
19
-
-
78650294662
-
An oral syk kinase inhibitor in the treatment of rheumatoid arthritis: A 3 month randomized placebo controlled phase 2 study in patients with active RA who had failed biologic agents
-
M.C. Genovese, A. Kavanaugh, M.E. Weinblatt, C. Peterfy, J. Dicarlo, and M.L. White An oral syk kinase inhibitor in the treatment of rheumatoid arthritis: a 3 month randomized placebo controlled phase 2 study in patients with active RA who had failed biologic agents Arthritis Rheum 63 2011 337 345
-
(2011)
Arthritis Rheum
, vol.63
, pp. 337-345
-
-
Genovese, M.C.1
Kavanaugh, A.2
Weinblatt, M.E.3
Peterfy, C.4
Dicarlo, J.5
White, M.L.6
-
20
-
-
33745020186
-
Improvement of psoriasis and cutaneous side-effects during tyrosine kinase inhibitor therapy for renal metastatic adenocarcinoma: A role for epidermal growth factor receptor (EGFR) inhibitors in psoriasis?
-
E. Wierzbicka, J.M. Tourani, and G. Guillet Improvement of psoriasis and cutaneous side-effects during tyrosine kinase inhibitor therapy for renal metastatic adenocarcinoma: a role for epidermal growth factor receptor (EGFR) inhibitors in psoriasis? Br J Dermatol 155 2006 213 214
-
(2006)
Br J Dermatol
, vol.155
, pp. 213-214
-
-
Wierzbicka, E.1
Tourani, J.M.2
Guillet, G.3
-
21
-
-
77950408289
-
Improvement of psoriasis in a lung cancer patient treated with erlotinib
-
E. Giroux Leprieur, S. Friard, and L.J. Couderc Improvement of psoriasis in a lung cancer patient treated with erlotinib Eur J Dermatol 20 2010 243 244
-
(2010)
Eur J Dermatol
, vol.20
, pp. 243-244
-
-
Giroux Leprieur, E.1
Friard, S.2
Couderc, L.J.3
-
22
-
-
84862103871
-
A case of rapid improvement of severe psoriasis during molecular-targeted therapy using an epidermal growth factor receptor tyrosine kinase inhibitor for metastatic lung adenocarcinoma
-
N. Oyama, F. Kaneko, A. Togashi, and T. Yamamoto A case of rapid improvement of severe psoriasis during molecular-targeted therapy using an epidermal growth factor receptor tyrosine kinase inhibitor for metastatic lung adenocarcinoma J Am Acad Dermatol 66 2012 e251 e253
-
(2012)
J Am Acad Dermatol
, vol.66
-
-
Oyama, N.1
Kaneko, F.2
Togashi, A.3
Yamamoto, T.4
-
23
-
-
78650496401
-
Evaluation of the novel protein kinase C inhibitor sotrastaurin as immunosuppressive therapy after renal transplantation
-
M. Matz, M. Naik, M.F. Mashreghi, P. Glander, H.H. Neumayer, and K. Budde Evaluation of the novel protein kinase C inhibitor sotrastaurin as immunosuppressive therapy after renal transplantation Expert Opin Drug Metab Toxicol 7 2011 103 113
-
(2011)
Expert Opin Drug Metab Toxicol
, vol.7
, pp. 103-113
-
-
Matz, M.1
Naik, M.2
Mashreghi, M.F.3
Glander, P.4
Neumayer, H.H.5
Budde, K.6
-
24
-
-
84876366673
-
Psoriasis treatments: A review of the current research pipeline
-
A. Golant, and E. Guttman-Yassky Psoriasis treatments: A review of the current research pipeline Psoriasis Forum 17 2011 11 23
-
(2011)
Psoriasis Forum
, vol.17
, pp. 11-23
-
-
Golant, A.1
Guttman-Yassky, E.2
-
25
-
-
51349152055
-
The PKC inhibitor AEB071 may be a therapeutic option for psoriasis
-
H. Skevara The PKC inhibitor AEB071 may be a therapeutic option for psoriasis J Clin Invest 118 2008 3151 3159
-
(2008)
J Clin Invest
, vol.118
, pp. 3151-3159
-
-
Skevara, H.1
-
27
-
-
75749092187
-
Go upstream, young man: Lessons learned from the p38 saga
-
D. Hammaker, and G.S. Firestein Go upstream, young man: lessons learned from the p38 saga Ann Rheum Dis 69 Suppl 1 2010 i77 i82
-
(2010)
Ann Rheum Dis
, vol.69
, Issue.SUPPL. 1
-
-
Hammaker, D.1
Firestein, G.S.2
|