Association of single nucleotide polymorphisms on Interleukin 17 receptor A (IL17RA) gene with aspirin hypersensitivity in asthmatics

Human Immunology

Volumn 74, Issue 5, 2013, Pages 598-606

  Park, Jong Sook ^a   Park, Byung Lae ^b,i   Kim, Myung ok ^a   Heo, Jeong Seok ^a   Jung, Ji Sun ^a   Bae, Da Jeong ^a   Uh, Soo Taek ^a   Kim, Mi Kyeong ^c   Choi, Inseon S ^d   Cho, Sang Heon ^e   Hong, Chein Soo ^f   Lee, Jae Young ^g   Choi, Byoung Whui ^h   Shin, Hyoung Doo ^b,i   Park, Choon Sik ^a  

^a Soonchunhyang University   (South Korea)

^b SNP Genetics Inc   (South Korea)

^c Chungbuk National University College of Medicine   (South Korea)

^d Chonnam National University Medical School   (South Korea)

^e Seoul National University College of Medicine   (South Korea)

^f Yonsei University College of Medicine   (South Korea)

^g Hallym University   (South Korea)

^h Chung Ang University   (South Korea)

ⁱ Sogang University   (South Korea)

Author keywords

Aspirin; Asthma; IL17RA; Polymorphism

Indexed keywords

ACETYLSALICYLIC ACID; CD14 ANTIGEN; INTERLEUKIN 17 RECEPTOR; MESSENGER RNA;

ADOLESCENT; ADULT; AGED; ARTICLE; ASPIRIN EXACERBATED RESPIRATORY DISEASE; ASTHMA; CONTROLLED STUDY; DYSPNEA; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPING TECHNIQUE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; SINGLE NUCLEOTIDE POLYMORPHISM; WHEEZING;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD14; ASTHMA, ASPIRIN-INDUCED; CHILD; CHILD, PRESCHOOL; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; MONOCYTES; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, INTERLEUKIN-17; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; YOUNG ADULT;

EID: 84876345701     PISSN: 01988859     EISSN: 18791166     Source Type: Journal    
DOI: 10.1016/j.humimm.2012.11.002     Document Type: Article

References (35)

1. Samter M., Beers R.F. Concerning the nature of intolerance to aspirin. J Allergy 1967, 40:281-293.
2. Stevenson D.D., Sanchez-Borges M., Szczeklik A. Classification of allergic and pseudoallergic reactions to drugs that inhibit cyclooxygenase enzymes. Ann Allergy Asthma Immunol 2001, 87:177-180.
3. Sousa A.R., Parikh A., Scadding G., Corrigan C.J., Lee T.H. Leukotriene-receptor expression on nasal mucosal inflammatory cells in aspirin-sensitive rhinosinusitis. N Engl J Med 2002, 347:1493-1499.
4. Szczeklik A. The cyclooxygenase theory of aspirin-induced asthma. Eur Respir J 1990, 3:588-593.
5. Sanak M., Simon H.U., Szczeklik A. Leukotriene C4 synthase promoter polymorphism and risk of aspirin-induced asthma. Lancet 1997, 350:1599-1600.
6. Choi J.H., Park H.S., Oh H.B., Lee J.H., Suh Y.J., Park C.S., et al. Leukotriene-related gene polymorphisms in ASA-intolerant asthma: an association with a haplotype of 5-lipoxygenase. Hum Genet 2004, 114:337-344.
7. Kim S.H., Oh J.M., Kim Y.S., Palmer L.J., Suh C.H., Nahm D.H., et al. Cysteinyl leukotriene receptor 1 promoter polymorphism is associated with aspirin-intolerant asthma in males. Clin Exp Allergy 2006, 36:433-439.
8. Park J.S., Chang H.S., Park C.S., Lee J.H., Lee Y.M., Choi J.H. Association analysis of cysteinyl-leukotriene receptor 2 (CYCLTR2) polymorphisms with aspirin intolerance in asthmatics. Pharmacogenet Genomics 2005, 15:483-492.
9. Kim S.H., Choi J.H., Park H.S., Holloway J.W., Lee S.K., Park C.S., et al. Association of thromboxane a2 receptor gene polymorphism with the phenotype of acetyl salicylic acid-intolerant asthma. Clin Exp Allergy 2005, 35:585-590.
10. Leff A.R. Regulation of leukotrienes in the management of asthma: biology and clinical therapy. Annu Rev Med 2001, 52:1-14.
11. Dahlen S.E., Malmstrom K., Nizankowska E., Dahlen B., Kuna P., Kowalski M., et al. Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist: a randomized, double-blind, placebo-controlled trial. Am J Respir Crit Care Med 2002, 165:9-14.
12. Park J.S., Jang A.S., Park S.W., Lee Y.M., Uh S.T., Kim Y.H., et al. Protection of leukotriene receptor antagonist against aspirin-induced bronchospasm in asthmatics. Allergy Asthma Immunol Res 2010, 2(1):48-54. Epub 2009 Dec 30. 10.4168/aair.2010.2.1.48.
13. Szczeklik A., Stevenson D.D. Aspirin-induced asthma: advances in pathogenesis, diagnosis, and management. J Allergy Clin Immunol 2003, 111:913-921. quiz 922.
14. Kim S.H., Yang E.M., Lee H.N., Cho B.Y., Ye Y.M., Park H.S. Combined effect of IL-10 and TGF-beta1 promoter polymorphisms as a risk factor for aspirin-intolerant asthma and rhinosinusitis. Allergy 2009, 64:1221-1225.
15. Oh S.H., Park S.M., Park J.S., Jang A.S., Lee Y.M., Uh S.T., et al. Association analysis of peroxisome proliferator-activated receptors gamma gene polymorphisms with asprin hypersensitivity in asthmatics. Allergy Asthma Immunol Res 2009, 1:30-35.
16. Kawaguchi M., Adachi M., Oda N., Kokubu F., Huang S.K. IL-17 cytokine family. J Allergy Clin Immunol 2004, 114:1265-1273. quiz 1274.
17. Louten J., Boniface K., de Waal Malefyt R. Development and function of th17 cells in health and disease. J Allergy Clin Immunol 2009, 123:1004-1011.
18. Gaffen S.L. Structure and signalling in the IL-17 receptor family. Nat Rev Immunol 2009, 9:556-567.
19. Yao Z., Fanslow W.C., Seldin M.F., Rousseau A.M., Painter S.L., Comeau M.R., et al. Herpesvirus saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity 1995, 3:811-821.
20. Miljkovic D., Cvetkovic I., Vuckovic O., Stosic-Grujicic S., Mostarica Stojkovic M., Trajkovic V. The role of interleukin-17 in inducible nitric oxide synthase-mediated nitric oxide production in endothelial cells. Cell Mol Life Sci 2003, 60:518-525.
21. Wong C.K., Cheung P.F., Ip W.K., Lam C.W. Interleukin-25-induced chemokines and interleukin-6 release from eosinophils is mediated by p38 mitogen-activated protein kinase, c-jun n-terminal kinase, and nuclear factor-kappa b. Am J Respir Cell Mol Biol 2005, 33:186-194.
22. Jung J.S., Park B.L., Cheong H.S., Bae J.S., Kim J.H., Chang H.S., et al. Association of IL-17rb gene polymorphism with asthma. Chest 2009, 135:1173-1180.
23. Bateman E.D., Hurd S.S., Barnes P.J., Bousquet J., Drazen J.M., FitzGerald M., et al. Global strategy for asthma management and prevention: gina executive summary. Eur Respir J 2008, 31:143-178.
24. Nizankowska-Mogilnicka E., Bochenek G., Mastalerz L., Swierczynska M., Picado C., Scadding G., et al. EAACI/GA2LEN guideline: aspirin provocation tests for diagnosis of aspirin hypersensitivity. Allergy 2007, 62:1111-1118.
25. Hun Soo Chang, Park Jong-Sook, Jang An-Soo, Park Sung-Woo, Uh Soo-Taek, Kim Young Hoon, Park Choon-Sik. Diagnostic Value of Clinical Parameters in the Prediction of Aspirin-Exacerbated Respiratory Disease in Asthma. Allergy Asthma, Immunol Res 2011;3(4):256-264. http://dx.doi.org/10.4168/aair.2011.3.4.256.
26. Livak K.J. Allelic discrimination using fluorogenic probes and the 5' nuclease assay. Genet Anal 1999, 14:143-149.
27. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987, 162:156-159.
28. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta c(t)) method. Methods 2001, 25:402-408.
29. Hedrick P.W. Gametic disequilibrium measures: proceed with caution. Genetics 1987, 117:331-341.
30. Stephens M., Smith N.J., Donnelly P. A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 2001, 68:978-989.
31. Su A.I., Wiltshire T., Batalov S., Lapp H., Ching K.A., Block D., et al. A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci U S A 2004, 101:6062-6067.
32. O'Connor W., Kamanaka M., Booth C.J., Town T., Nakae S., Iwakura Y., et al. A protective function for interleukin 17A in T cell-mediated intestinal inflammation. Nat Immunol 2009, 10:603-609.
33. Paradowska A., Masliniski W., Grzybowska-Kowalczyk A., Lacki J. The function of interleukin 17 in the pathogenesis of rheumatoid arthritis. Arch Immunol Ther Exp (Warsz) 2007, 55:329-334.
34. Dong C. Diversification of T-helper-cell lineages: finding the family root of IL-17-producing cells. Nat Rev Immunol 2006, 6:329-333.
35. McGovern D.P., Rotter J.I., Mei L., Haritunians T., Landers C., Derkowski C., et al. Genetic epistasis of IL23/IL17 pathway genes in crohn's disease. Inflamm Bowel Dis 2009, 15:883-889.