In vitro and computational studies of transdermal perfusion of nanoformulations containing a large molecular weight protein

Colloids and Surfaces B: Biointerfaces

Volumn 108, Issue , 2013, Pages 271-278

  Martins, Madalena ^a   Azoia, Nuno G ^a   Ribeiro, Artur ^a   Shimanovich, Ulyana ^b   Silva, Carla ^a   Cavaco Paulo, Artur ^a  

^a UNIVERSITY OF MINHO   (Portugal)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Hydrophilic macromolecules; Nanodispersion; Protein; Surfactant; Transdermal perfusion

Indexed keywords

BOVINE SERUM ALBUMINS; COMPUTATIONAL STUDIES; HYDROPHILIC MACROMOLECULES; MOLECULAR DYNAMICS SIMULATIONS; NANO-DISPERSIONS; NANOEMULSION; SKIN PERMEATION; TRANSDERMAL;

LIPID BILAYERS; MOLECULAR DYNAMICS; SURFACE ACTIVE AGENTS;

PROTEINS;

BOVINE SERUM ALBUMIN; FLUORESCEIN ISOTHIOCYANATE; MYRISTIC ACID ISOPROPYL ESTER; SUCROSE ESTER; SURFACTANT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISPERSION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; ESTHETICS; IN VITRO STUDY; LIPID BILAYER; MOLECULAR DYNAMICS; MOLECULAR WEIGHT; NANODISPERSION; NANOEMULSION; NANOFORMULATION; NANOTECHNOLOGY; NONHUMAN; PRIORITY JOURNAL; SKIN PERMEABILITY;

ADMINISTRATION, CUTANEOUS; ANIMALS; CATTLE; EMULSIONS; FLUORESCENT DYES; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KINETICS; LIPID BILAYERS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR WEIGHT; MYRISTATES; NANOSTRUCTURES; SERUM ALBUMIN, BOVINE; SKIN; SURFACE-ACTIVE AGENTS; SWINE;

BOVINAE;

EID: 84876323919     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2013.02.032     Document Type: Article

References (49)

1. Cevc G., Vierl U. Nanotechnology and the transdermal route: a state of the art review and critical appraisal. J. Control. Release 2010, 141:277-299.
2. Richert R., Schrader A., Schrader K. Transdermal delivery of two antioxidants from different cosmetic formulations. Int. J. Cosmet. Sci. 2003, 25.
3. Prausnitz M.R., Langer R. Transdermal drug delivery. Nat. Biotechnol. 2008, 26:1261-1268.
4. Karande P., Jain A., Ergun K., Kispersky V., Mitragotri S. Design principles of chemical penetration enhancers for transdermal drug delivery. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:4688-4693.
5. Scheuplein R.J., Blank I.H. Permeability of the skin. Physiol. Rev. 1971, 51:702-747.
6. Masukawa Y., Narita H., Shimizu E., Kondo N., Sugai Y., Oba T., Homma R., Ishikawa J., Takagi Y., Kitahara T., Takema Y., Kita K. Characterization of overall ceramide species in human stratum corneum. J. Lipid Res. 2008, 49:1466-1476.
7. Masukawa Y., Narita H., Sato H., Naoe A., Kondo N., Sugai Y., Oba T., Homma R., Ishikawa J., Takagi Y., Kitahara T. Comprehensive quantification of ceramide species in human stratum corneum. J. Lipid Res. 2009, 50:1708-1719.
8. t'Kindt R., Jorge L., Dumont E., Couturon P., David F., Sandra P., Sandra K. Profiling and characterizing skin ceramides using reversed-phase liquid chromatography-quadrupole time-of-flight mass spectrometry. Anal. Chem. 2012, 84:403-411.
9. Norlén L., Nicander I., Lundsjö A., Cronholm T., Forslind B. A new HPLC-based method for the quantitative analysis of inner stratum corneum lipids with special reference to the free fatty acid fraction. Arch. Dermatol. Res. 1998, 290:508-516.
10. King M.J., Badea I., Solomon J., Kumar P., Gaspar J.K., Foldvari M. Transdermal delivery of insulin from a novel biphasic lipid system in diabetic rats. Diab. Technol. Ther. 2002, 4(4):479-488.
11. Tahara Y., Honda S., Kamiya N., Piao H., Hirata A., Hayakawa E., Fujii T., Goto M. A solid-in-oil nanodispersion for transcutaneous protein delivery. J. Control. Release 2008, 131:14-18.
12. Pissuwan D., Nose K., Kurihara R., Kaneko K., Tahara Y., Kamiya N., Goto M., Katayama Y., Niidome T. A solid-in-oil dispersion of gold nanorods can enhance transdermal protein delivery and skin vaccination. Small 2011, 7:215-220.
13. Piao H., Kamiya N., Hirata A., Fujii T., Goto M. A novel solid-in-oil nanosuspension for transdermal delivery of diclofenac sodium. Pharm. Res. 2007, 25:896-901.
14. Yoshiura H., Hashida M., Kamiya N., Goto M. Factors affecting protein release behavior from surfactant-protein complexes under physiological conditions. Int. J. Pharm. 2007, 338:174-179.
15. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 1951, 193(1):265-275.
16. Hess B., Kutzner C., van der Spoel D., Lindahl E. GROMACS algorithms for highly efficient, load-balanced, and scalable molecular simulation. J. Chem. Theory Comput. 2008, 4:435-447.
17. Marrink S.J., Risselada H.J., Yefimov S., Tieleman D.P., de Vries A.H. The MARTINI force field: coarse grained model for biomolecular simulations. J. Phys. Chem. B 2007, 111:7812-7824.
18. Hess B., Bekker H., Berendsen H.J.C., Fraaije J.G.E.M., LINC.S. A linear constraint solver for molecular simulations. J. Comput. Chem. 1997, 18:1463-1472.
19. Berendsen H.J.C., Postma J.P.M., van Gunsteren W.F., DiNola A., Haak J.R. Molecular dynamics with coupling to an external bath. J. Chem. Phys. 1984, 81:3684.
20. Sommer B., Dingersen T., Gamroth C., Schneider S.E., Rubert S., Kruger J., Dietz K.-J. CELLmicrocosmos 2.2 MembraneEditor: a modular interactive shape-based software approach to solve heterogeneous membrane packing problems. J. Chem. Inform. Model. 2011, 51:1165-1182.
21. Huzil J.T., Sivaloganathan S., Kohandel M., Foldvari M., Kotsireas I., Melnik R., West B. Modeling the effects of lipid composition on stratum corneum bilayers using molecular dynamics simulations. AIP Conf. Proc. 2011, 1368:175-178.
22. Hoopes M.I., Noro M.G., Longo M.L., Faller R. Bilayer structure and lipid dynamics in a model stratum corneum with oleic acid. J. Phys. Chem. B 2011, 115:3164-3171.
23. Lee W.S. Integral hair lipid in human hair follicle. J. Dermatol. Sci. 2011, 64:153-158.
24. Silva R., Ferreira H., Azoia N.G., Shimanovich U., Freddi G., Gedanken A., Cavaco-Paulo A. Insights on the mechanism of formation of protein microspheres in a biphasic system. Mol. Pharm. 2012, 9:3079-3088.
25. Gopalakrishnana S., Sujathaa R. Ageing studies of cardanol based polyurethanes. Res. J. Pharm. Biol. Chem. Sci. 2011, 2.
26. Blasco M., García-Reverter J., Casas E., Riera E. Effect of high power ultrasounds on mass-transfer zone in supercritical fluid extraction processes. Proceedings of 20th International Congress on Acoustics 2010.
27. Durbha K.S., Aravamudan K. Quantification of surface area and intrinsic mass transfer coefficient for ultrasound-assisted dissolution process of a sparingly soluble solid dispersed in aqueous solutions. Ultrason. Sonochem. 2012, 19:509-521.
28. Rae J., Ashokkumar M., Eulaerts O., von Sonntag C., Reisse J., Grieser F. Estimation of ultrasound induced cavitation bubble temperatures in aqueous solutions. Ultrason. Sonochem. 2005, 12:325-329.
29. F. Marzulli, H.I. Maibach, Relevance of animal models: the hexachlorophene story, Maibach, H.I., New York, 1975.
30. Bronaugh R.L., Stewart R.F., Congdon E.R. Methods for in vitro percutaneous absorption studies II. Animal models for human skin. Toxicol. Appl. Pharmacol. 1982, 62:481-488.
31. Haigh J.M., Smith E.W. The selection and use of natural and synthetic membranes for in vitro diffusion experiments. Eur. J. Pharm. Sci. 1994, 2:311-330.
32. Morris G.M., Hopewell J.W. Epidermal cell kinetics of the pig: a review. Cell Prolif. 1990, 23:271-282.
33. Sullivan T.P., Eaglstein W.H., Davis S.C., Mertz P. The pig as a model for human wound healing. Wound Repair Regen. 2001, 9:66-76.
34. Harunari N., Zhu K.Q., Armendariz R.T., Deubner H., Muangman P., Carrougher G.J., Isik F.F., Gibran N.S., Engrav L.H. Histology of the thick scar on the female, red Duroc pig: final similarities to human hypertrophic scar. Burns 2006, 32:669-677.
35. Gallo S.A., Sen A., Hensen M.L., Hui S.W. Time-dependent ultrastructural changes to porcine stratum corneum following an electric pulse. Biophys. J. 1999, 76:2824-2832.
36. Holbrook K.A., Odland G.F. Regional differences in the thickness (cell layers) of the human stratum corneum: an ultrastructural analysis. J. Invest. Dermatol. 1974, 62:415-422.
37. Wester R.C., Melendres J., Sedik L., Maibach H., Riviere J.E. Percutaneous absorption of salicylic acid, theophylline, 2.4-dimethylamine, diethyl hexyl phthalic acid, andp-aminobenzoic acid in the isolated perfused porcine skin flap compared to manin vivo. Toxicol. Appl. Pharmacol. 1998, 151:159-165.
38. Singh S., Zhao K., Singh J. In vitro permeability and binding of hydrocarbons in pig ear and human abdominal skin drug and chemical. Toxicology 2002, 25:83-92.
39. Sekkat N., Kalia Y.N., Guy R.H. Porcine ear skin as a model for the assessment of transdermal drug delivery to premature neonates. Pharm. Res. 2004, 21:1390-1397.
40. Simon G.A., Maibach H.I. The pig as an experimental animal model of percutaneous permeation in man: qualitative and quantitative observations - an overview. Skin Pharmacol. Appl. Skin Physiol. 2000, 15:229-234.
41. Arellano A., Santoyo S., Marti{dotless}ón C., Ygartua P. Influence of propylene glycol and isopropyl myristate on the in vitro percutaneous penetration of diclofenac sodium from carbopol gels. Eur. J. Pharm. Sci. 1999, 7:129-135.
42. Leopold C.S., Lippold B.C. An attempt to clarify the mechanism of the penetration enhancing effects of lipophilic vehicles with differential scanning calorimetry (DSC). J. Pharm. Pharmacol. 1995, 47(4):276-281.
43. Sato K., Sugibayashi K., Morimoto Y. Effect and mode of action of aliphatic esters on the in vitro skin permeation of nicorandil. Int. J. Pharm. 1988, 43:31-40.
44. Klaffenbach P., Kronenfeld D. Analysis of impurities of isopropyl myristate by gas-liquid chromatography. J. Chromatogr. A 1997, 767:330-334.
45. Moser K., Kriwet K., Naik A., Kalia Y.N., Guy R.H. Passive skin penetration enhancement and its quantification in vitro. Eur. J. Pharm. Biopharm. 2001, 52:103-112.
46. Notman R., Anwar J. Breaching the skin barrier - insights from molecular simulation of model membranes. Adv. Drug Deliv. Rev. 2012.
47. Notman R., den Otter W.K., Noro M.G., Briels W.J., Anwar J. The permeability enhancing mechanism of DMSO in ceramide bilayers simulated by molecular dynamics. Biophys. J. 2007, 93:2056-2068.
48. Das C., Noro M.G., Olmsted P.D. Simulation studies of stratum corneum lipid mixtures. Biophys. J. 2009, 97:1941-1951.
49. Schreiner V., Gooris G.S., Pfeiffer S., Lanzendorfer G., Wenck H., Diembeck W., Proksch E., Bouwstra J. Barrier characteristics of different human skin types investigated with X-ray diffraction, lipid analysis, and electron microscopy imaging. J. Invest. Dermatol. 2000, 114:654-660.