Comprehensive quantification of ceramide species in human stratum corneum

Journal of Lipid Research

Volumn 50, Issue 8, 2009, Pages 1708-1719

  Masukawa, Yoshinori ^a   Narita, Hirofumi ^a   Sato, Hirayuki ^a   Naoe, Ayano ^a   Kondo, Naoki ^a   Sugai, Yoshiya ^a   Oba, Tsuyoshi ^a   Homma, Rika ^a   Ishikawa, Junko ^a   Takagi, Yutaka ^a   Kitahara, Takashi ^a  

^a KAO CORPORATION   (Japan)

Author keywords

High sensitivity; Normal phase liquid chromatography electrospray ionization mass spectrometry; Relative response; Simultaneous selected ion monitoring; Skin

Indexed keywords

CERAMIDE; CELL EXTRACT; FATTY ACID;

ADULT; ARTICLE; CALCULATION; CALIBRATION; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; LIPIDOMICS; MALE; MEASUREMENT; MONITORING; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; STRATUM CORNEUM; THIN LAYER CHROMATOGRAPHY; CHEEK; CHEMISTRY; EPIDERMIS; FOREARM; INSTRUMENTATION; LIQUID CHROMATOGRAPHY; METHODOLOGY;

ADULT; CELL EXTRACTS; CERAMIDES; CHEEK; CHROMATOGRAPHY, LIQUID; EPIDERMIS; FATTY ACIDS; FOREARM; HUMANS; MALE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 69449098731     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.D800055-JLR200     Document Type: Article

References (47)

1. Spener, F., M. Lagarde, A. Geloen, and M. Record. 2003. What is lipidomics? Eur. J. Lipid Sci. Technol. 105: 481-482.
2. Mano, N., Y. Oda, K. Yamada, N. Asakawa, and K. Katayama. 1997. Simultaneous quantitative determination method for sphingolipid metabolites by liquid chromatography/ionspray ionization tandem mass spectrometry. Anal. Biochem. 244: 291-300.
3. Han, X., and R. W. Gross. 2001. Quantitative analysis and molecular species fingerprinting of triacylglyceride molecular species directly from lipid extracts of biological samples by electrospray ionization tandem mass spectrometry. Anal. Biochem. 295: 88-100.
4. Koivusalo, M., P. Haimi, L. Heikinheimo, R. Kostiainen, and P. Somerharju. 2001. Quantitative determination of phospholipid compositions by ESI-MS: effects of acyl chain length, unsaturation, and lipid concentration on instrument response. J. Lipid Res. 42: 663-672.
5. Han, X., and R. W. Gross. 2003. Global analyses of cellular lipidomes directly from crude extracts of biological samples by ESI tandem mass spectrometry: a bridge to lipidomics. J. Lipid Res. 44: 1071-1079.
6. Taguchi, R., T. Houjou, H. Nakanishi, T. Yamazaki, M. Ishida, M. Imagawa, and T. Shimizu. 2005. Focused lipidomics by tandem mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 823: 26-36.
7. Hermansson, M., A. Uphoff, R. Käkelä, and P. Somerharju. 2005. Automated quantitative analysis of complex lipidomes by liquid chromatography/mass spectrometry. Anal. Chem. 77: 2166-2175.
8. Postle, A. D., L. W. Gonzales, W. Bernhard, G. T. Clark, M. H. Godinez, R. I. Godinez, and P. L. Ballard. 2006. Lipidomics of cellular and secreted phospholipids from differentiated human fetal type II alveolar epithelial cells. J. Lipid Res. 47: 1322-1331.
9. Bang, D. Y., E. Ahn, and M. H. Moon. 2007. Shotgun analysis of phospholipids from mouse liver and brain by nanoflow liquid chromatography/tandem mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 852: 268-277.
10. Roberts, L. D., G. McCombie, C. M. Timan, and J. L. Griffin. 2008. A matter of fat: an introduction to lipidomic profi ling methods. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 871: 174-181.
11. Esch, S. W., T. D. Williams, S. Biswas, A. Chakrabarty, and S. M. Levine. 2003. Sphingolipid profi le in the CNS of the twicher (globoid cell leukodystrophy) mouse: a lipidomics approach. Cell. Mol. Biol. 49: 779-787.
12. Mizutani, Y., A. Kihara, H. Chiba, H. Tojo, and Y. Igarashi. 2008. 2-Hydroxy-ceramide synthesis by ceramide synthase family: enzymatic basis for the preference of FA chain length. J. Lipid Res. 49:2356-2364.
13. Pettus, B. J., M. Baes, M. Busman, Y. A. Hannun, and P. P. van Veldhoven. 2004. Mass spectrometric analysis of ceramide perturbations in brain and fibroblasts of mice and human patients with peroxisomal disorders. Rapid Commun. Mass Spectrom. 18: 1569-1574.
14. Liebisch, G., W. Drobnik, M. Reil, B. Trümbach, R. Arneche, B. Olgemöller, A. Roscher, and G. Schmitz. 1999. Quantitative measurement of different ceramide species from crude cellular extracts by electrospray ionization tandem mass spectrometry (ESI-MS/MS). J. Lipid Res. 40: 1539-1546.
15. Han, X. 2002. Characterization and direct quantitation of ceramide molecular species from lipid extracts of biological samples by electrospray ionization tandem mass spectrometry. Anal. Biochem. 302: 199-212.
16. Hannun, Y. A. 1996. Functions of ceramide in coordinating cellular responses to stress. Science. 274: 1855-1859.
17. Pettus, B. J., C. E. Chalfant, and Y. A. Hannun. 2002. Ceramide in apoptosis: an overview and current perspectives. Biochim. Biophys. Acta. 1585: 114-125.
18. Elias, P. M. 1983. Epidermal lipids, barrier, function, and desquamation. J. Invest. Dermatol. 80: 44s-49s.
19. Imokawa, G., S. Akasaki, M. Hattori, and N. Yoshizuka. 1986. Selective recovery of deranged water-holding properties by stratum corneum lipids. J. Invest. Dermatol. 87: 758-761.
20. Wertz, P. W., K. C. Madison, and D. T. Downing. 1989. Covalently bound lipids of human stratum corneum. J. Invest. Dermatol. 92: 109-111.
21. Robson, K. J., M. E. Stewart, S. Michelsen, N. D. Lazo, and D. T. Downing. 1994. 6-hydroxy-4-sphingenine in human epidermal ceramides. J. Lipid Res. 35: 2060-2068.
22. Vietzke, J. P., O. Brandt, D. Abeck, C. Rapp, M. Strassner, V. Schreiner, and U. Hintze. 2001. Comparative investigation of human stratum corneum ceramides. Lipids. 36: 299-304.
23. Ponec, M., A. Weerheim, P. Lankhorst, and P. W. Wertz. 2003. New acylceramide in native and reconstructed epidermis. J. Invest. Dermatol. 120: 581-588.
24. Masukawa, Y., H. Narita, E. Shimizu, N. Kondo, Y. Sugai, T. Oba, R. Homma, J. Ishikawa, Y. Takagi, T. Kitahara, et al. 2008. Characterization of overall ceramide species in human stratum corneum. J. Lipid Res. 49: 1466-1476.
25. Wertz, P. W., M. C. Miethke, S. A. Long, J. S. Strauss, and D. T. Downing. 1985. The composition of the ceramides from human stratum corneum and from comedones. J. Invest. Dermatol. 84: 410-412.
26. Long, S. A., P. W. Wertz, J. S. Strauss, and D. T. Downing. 1985. Human stratum corneum polar lipids and desquamation. Arch. Dermatol. Res. 277: 284-287.
27. Wertz, P. W., D. C. Swartzendruber, K. C. Madison, and D. T. Downing. 1987. Composition and morphology of epidermal cyst lipids. J. Invest. Dermatol. 89: 419-425.
28. Do, U. H., P. T. Pei, and R. D. Minard. 1981. Separation of molecular species of ceramides as benzoyl and p- nitrobenzoyl derivatives by high performance liquid chromatography. Lipids. 16: 855-862.
29. Masukawa, Y., H. Tsujimura, and G. Imokawa. 2005. A systematic method for the sensitive and specific determination of hair lipids in combination with chromatography. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 823: 131-142.
30. Vietzke, J. P., M. Strassner, and U. Hintze. 1999. Separation and identification of ceramides in the human stratum corneum by high-performance liquid chromatography coupled with electrospray ionization mass spectrometry and electrospray multiple-stage mass spectrometry profiling. Chromatographia. 50: 15-20.
31. Raith, K., S. Zellmer, J. Lasch, and R. H. H. Neubert. 2000. Profiling of human stratum corneum ceramides by liquid chromatographyelectrospray mass spectrometry. Anal. Chim. Acta. 418: 167-173.
32. Camera, E., M. Picardo, C. Presutti, P. Catarcini, and S. Fanali. 2004. Separation and characterization of sphingoceramides by high-performance liquid chromatography-electrospray ionization mass spectrometry. J. Sep. Sci. 27: 971-976.
33. Hsu, F. F., J. Turk, M. E. Stewart, and D. T. Downing. 2002. Structural studies on ceramides as lithiated dissociation by low energy collisional-activated dissociation tandem mass spectrometry with electrospray ionization. J. Am. Soc. Mass Spectrom. 13: 680-6954.
34. Trommer, H., M. Platzer, R. Wolf, and R. H. H. Neubert. 2003. Mass spectrometric examinations of stratum corneum lipid models exposed to ultraviolet irradiation. Skin Pharmacol. Appl. Skin Physiol. 16: 291-304.
35. Yamane, M. 2003. Simultaneous quantitative determination method for ceramide species from crude cellular extracts by high-performance liquid chromatography-thermospray mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 783: 181-190.
36. Farwanah, H., P. Nuhn, R. H. H. Neubert, and K. Raith. 2003. Normal-phase liquid chromatographic separation of stratum corneum ceramides with detection by evaporative light scattering and atmospheric pressure chemical ionization mass spectrometry. Anal. Chim. Acta. 492: 233-239.
37. Farwanah, H., K. Raith, R. H. H. Neubert, and J. Wohlrab. 2005. Ceramide profiles of the uninvolved skin in atopic dermatitis and psoriasis are comparable to those of healthy skin. Arch. Dermatol. Res. 296: 514-521.
38. Farwanah, H., J. Wohlrab, R. H. H. Neubert, and K. Raith. 2005. Profiling of human stratum corneum ceramides by means of normal phase LC/ APCI-MS. Anal. Bioanal. Chem. 383: 632-637.
39. Farwanah, H., B. Pierstorff, C. E. H. Schmelzer, K. Raith, R. H. H. Neubert, K. Kolter, and K. Sandhoff. 2007. Separation and mass spectrometric characterization of covalently bound skin ceramide profi les using LC/APCI-MS and nano-ESI-MS/MS. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 852: 562-570.
40. Motta, S., M. Monti, S. Sesana, R. Caputo, S. Carelli, and R. Ghidoni. 1993. Ceramide composition of the psoriatic scale. Biochim. Biophys. Acta. 1182: 147-151.
41. Smith, P. K., R. I. Krohn, G. T. Hermanson, A. K. Mallia, F. H. Gartner, M. D. Provenzano, E. K. Fujimoto, N. M. Goeke, B. J. Olson, and D. C. Klenk. 1995. Measurement of protein using bicinchoninic acid. Anal. Biochem. 150: 76-85.
42. Imokawa, G., A. Abe, K. Jin, Y. Higaki, M. Kawashima, and A. Hidano. 1991. Decreased level of ceramides in stratum corneum of atopic dermatitis: an etiologic factor in atopic dry skin? J. Invest. Dermatol. 96: 523-526.
43. Wertz, P. W. 1992. Epidermal lipids. Semin. Dermatol. 11: 106-113.
44. Yardley, H. J., and R. Summerly. 1981. Lipid composition and metabolism in normal and diseased epidermis. Pharmacol. Ther. 13: 357-383.
45. Nicolaides, N. 1974. Skin lipids: their biochemical uniqueness. Science. 186: 19-26.
46. Masukawa, Y., and H. Tsujimura. 2007. Highly sensitive determination of diverse ceramides in human hair using reversed-phase highperformance liquid chromatography-electrospray ionization mass spectrometry. Lipids. 42: 275-290.
47. Muñoz-Garcia, A., J. Ro, J. C. Brown, and J. B. Williams. 2006. Identification of complex mixtures of sphingolipids in the stratum corneum by reversed-phase high-performance liquid chromatography and atmospheric pressure photospray ionization mass spectrometry. J. Chromatogr. A. 1133: 58-68.