Astrocyte GRK2 as a novel regulator of glutamate transport and brain damage

Neurobiology of Disease

Volumn 54, Issue , 2013, Pages 206-215

  Nijboer, Cora H ^a   Heijnen, Cobi J ^a,b   Degos, Vincent ^c,d   Willemen, Hanneke L M ^a   Gressens, Pierre ^c,d,e   Kavelaars, Annemieke ^a,b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c HÔPITAL ROBERT DEBRÉ   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Astrocytes; Cytoskeleton; Excitotoxicity; Ezrin; G protein coupled receptor kinase 2 (GRK2); GFAP; Glutamate transporter GLAST; Ischemic brain injury; Neuroprotection

Indexed keywords

EXCITATORY AMINO ACID TRANSPORTER; EZRIN; G PROTEIN COUPLED RECEPTOR KINASE 2; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN DAMAGE; CELL MEMBRANE; CONTROLLED STUDY; FEMALE; HYPOXIC ISCHEMIC ENCEPHALOPATHY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM;

AMINO ACID TRANSPORT SYSTEM X-AG; ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; BLOTTING, WESTERN; CYTOSKELETAL PROTEINS; DISEASE MODELS, ANIMAL; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; G-PROTEIN-COUPLED RECEPTOR KINASE 2; GLUTAMIC ACID; HYPOXIA-ISCHEMIA, BRAIN; IMMUNOPRECIPITATION; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RNA, SMALL INTERFERING;

EID: 84876318167     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2012.12.013     Document Type: Article

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