Extensive structural change of the envelope protein of dengue virus induced by a tuned ionic strength: Conformational and energetic analyses

Journal of Computer-Aided Molecular Design

Volumn 26, Issue 12, 2012, Pages 1311-1325

  Degrève, Léo ^a   Fuzo, Carlos A ^a   Caliri, Antonio ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Dengue; Flavivirus; Hydrogen bonds; Inter domains angle; Ionic strength; Molecular simulation; Protonated histidine

Indexed keywords

AMINO ACIDS; CELL MEMBRANES; CONFORMATIONS; CRYSTAL ATOMIC STRUCTURE; HEALTH RISKS; IONIC STRENGTH; MOLECULAR DYNAMICS; PRINCIPAL COMPONENT ANALYSIS; PROTEINS; PROTONATION; VIRUSES;

DENGUE; DENGUE VIRUS; EXTENSIVE SIMULATIONS; FLAVIVIRUS; HISTIDINE RESIDUES; INTER-DOMAIN; INTER-DOMAIN ANGLE; MOLECULAR SIMULATIONS; PROTONATED HISTIDINE; STRUCTURAL BEHAVIORS;

HYDROGEN BONDS;

VIRUS ENVELOPE PROTEIN;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DENGUE VIRUS; ENERGY TRANSFER; HYDROGEN BOND; IONIC STRENGTH; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR WEIGHT; PH; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PROTON TRANSPORT; STRUCTURE ANALYSIS; THERMODYNAMICS;

EID: 84876291662     PISSN: 0920654X     EISSN: 15734951     Source Type: Journal    
DOI: 10.1007/s10822-012-9616-4     Document Type: Article

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