Job strain-associated inflammatory burden and long-term risk of coronary events: Findings from the MONICA/KORA Augsburg case-cohort study

Psychosomatic Medicine

Volumn 75, Issue 3, 2013, Pages 317-325

  Emeny, Rebecca T ^a   Zierer, Astrid ^a   Lacruz, Maria Elena ^a   Baumert, Jens ^a   Herder, Christian ^b   Gornitzka, Gabriele ^b   Koenig, Wolfgang ^c   Thorand, Barbara ^a   Ladwig, Karl Heinz ^a,d  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b LEIBNIZ CENTER FOR DIABETES RESEARCH AT HEINRICH HEINE UNIVERSITY DÜSSELDORF   (Germany)

^c UNIVERSITY HOSPITAL ULM   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

coronary disease; inflammation; job strain; prospective; psychoneuroimmunology; work stress

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 18; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE MIGRATION INHIBITION FACTOR; MONOCYTE CHEMOTACTIC PROTEIN 1;

ADULT; ARTICLE; CARDIOMETABOLIC RISK; CONTROLLED STUDY; CORONARY RISK; ENDOTHELIAL DYSFUNCTION; FEMALE; HEART INFARCTION; HUMAN; INFLAMMATION; INTERVIEW; ISCHEMIC HEART DISEASE; JOB STRESS; KARASEK JOB STRAIN INDEX; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RATING SCALE; RISK ASSESSMENT; SUDDEN DEATH;

ADULT; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; COHORT STUDIES; CORONARY DISEASE; EMPLOYMENT; FEMALE; GERMANY; HUMANS; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-18; INTERLEUKIN-6; INTERLEUKIN-8; MALE; MIDDLE AGED; PROPORTIONAL HAZARDS MODELS; RISK FACTORS; STRESS, PSYCHOLOGICAL;

EID: 84876288330     PISSN: 00333174     EISSN: 15347796     Source Type: Journal    
DOI: 10.1097/PSY.0b013e3182860d63     Document Type: Article

References (56)

1. Kuper H, Marmot M. Job strain, job demands, decision latitude, and risk of coronary heart disease within the Whitehall II study. J Epidemiol Community Health 2003;57:147-53.
2. Hallqvist J, Diderichsen F, Theorell T, Reuterwall C, Ahlbom A. Is the effect of job strain on myocardial infarction risk due to interaction between high psychological demands and low decision latitude? Results from Stockholm Heart Epidemiology Program (SHEEP). Soc Sci Med 1998;46: 1405-15.
3. Eaker ED, Sullivan LM, Kelly-Hayes M, D'Agostino RB Sr, Benjamin EJ. Does job strain increase the risk for coronary heart disease or death in men and women? The Framingham Offspring Study. Am J Epidemiol 2004;159: 950-8.
4. Karasek RA. Job demands, decision latitude, and mental strain: implications for job redesign. Admin Sci Q 1979;24:285-308.
5. Siegrist J. Adverse health effects of high-effort/low-reward conditions. J Occup Health Psychol 1996;1:27-41.
6. Kivimaki M, Ferrie JE, Brunner E, Head J, Shipley MJ, Vahtera J, Marmot MG. Justice at work and reduced risk of coronary heart disease among employees: the Whitehall II Study. Arch Intern Med 2005;165:2245-51.
7. Aboa-Eboule C, Brisson C, Maunsell E, Masse B, Bourbonnais R, Vezina M, Milot A, Theroux P, Dagenais GR. Job strain and risk of acute recurrent coronary heart disease events. JAMA 2007;298:1652-60.
8. Eller NH, Netterstrom B, Gyntelberg F, Kristensen TS, Nielsen F, Steptoe A, Theorell T. Work-related psychosocial factors and the development of ischemic heart disease: a systematic review. Cardiol Rev 2009;17:83-97.
9. Radi S, Ostry A, LaMontagne AD. Job stress and other working conditions: relationships with smoking behaviors in a representative sample of working Australians. Am J Ind Med 2007;50:584-96.
10. Brunner EJ, Chandola T, Marmot MG. Prospective effect of job strain on general and central obesity in the Whitehall II Study. Am J Epidemiol 2007;165:828-37.
11. Hellerstedt WL, Jeffery RW. The association of job strain and health behaviours in men and women. Int J Epidemiol 1997;26:575-83.
12. Yarnell J. Stress at workVan independent risk factor for coronary heart disease? Eur Heart J 2008;29:579-80.
13. Belkic KL, Landsbergis PA, Schnall PL, Baker D. Is job strain a major source of cardiovascular disease risk? Scand J Work Environ Health 2004;30: 85-128.
14. Kivimaki M, Virtanen M, Elovainio M, Kouvonen A, Vaananen A, Vahtera J. Work stress in the etiology of coronary heart diseaseVa meta-analysis. Scand J Work Environ Health 2006;32:431-42.
15. Elovainio M, Ferrie JE, Singh-Manoux A, Gimeno D, De Vogli R, Shipley M, Vahtera J, Brunner E, Marmot MG, Kivimaki M. Organisational justice and markers of inflammation: the Whitehall II study. Occup Environ Med 2010;67:78-83.
16. Koenig W, Khuseyinova N, Baumert J, Thorand B, Loewel H, Chambless L, Meisinger C, Schneider A, Martin S, Kolb H, Herder C. Increased concentrations of C-reactive protein and IL-6 but not IL-18 are independently associated with incident coronary events in middle-aged men and women: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002. Arterioscler Thromb Vasc Biol 2006;26:2745-51.
17. Lowel H, Doring A, Schneider A, Heier M, Thorand B, Meisinger C. The MONICA Augsburg surveysVbasis for prospective cohort studies. Gesundheitswesen 2005;67(Suppl 1):S13-8.
18. Luepker RV, Apple FS, Christenson RH, Crow RS, Fortmann SP, Goff D, Goldberg RJ, Hand MM, Jaffe AS, Julian DG, Levy D, Manolio T, Mendis S, Mensah G, Pajak A, Prineas RJ, Reddy KS, Roger VL, Rosamond WD, Shahar E, Sharrett AR, Sorlie P, Tunstall-Pedoe H. Case definitions for acute coronary heart disease in epidemiology and clinical research studies: a statement from the AHA Council on Epidemiology and Prevention; AHA Statistics Committee; World Heart Federation Council on Epidemiology and Prevention; the European Society of Cardiology Working Group on Epidemiology and Prevention; Centers for Disease Control and Prevention; and the National Heart, Lung, and Blood Institute. Circulation 2003; 108:2543-9.
19. Alpert JS, Thygesen K, Antman E, Bassand JP. Myocardial infarction redefinedVa consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. J Am Coll Cardiol 2000;36:959-69.
20. Meisinger C, Thorand B, Schneider A, Stieber J, Doring A, Lowel H. Sex differences in risk factors for incident type 2 diabetes mellitus: the MONICA Augsburg cohort study. Arch Intern Med 2002;162:82-9.
21. Theorell T, Tsutsumi A, Hallquist J, Reuterwall C, Hogstedt C, Fredlund P, Emlund N, Johnson JV. Decision latitude, job strain, and myocardial infarction: a study of working men in Stockholm. The SHEEP Study Group. Stockholm Heart epidemiology Program. Am J Public Health 1998; 88:382-8.
22. Karasek R, Brisson C, Kawakami N, Houtman I, Bongers P, Amick B. The Job Content Questionnaire (JCQ): an instrument for internationally comparative assessments of psychosocial job characteristics. J Occup Health Psychol 1998;3:322-55.
23. Schnall PL, Landsbergis PA, Baker D. Job strain and cardiovascular disease. Annu Rev Public Health 1994;15:381-411.
24. Hutchinson WL, Koenig W, Frohlich M, Sund M, Lowe GDO, Pepys MB. Immunoradiometric assay of circulating C-reactive protein: age-related values in the adult general population. Clin Chem 2000;46:934-8.
25. Khuseyinova N, Imhof A, Trischler G, Rothenbacher D, Hutchinson WL, Pepys MB, Koenig W. Determination of C-reactive protein: comparison of three high-sensitivity immunoassays. Clin Chem 2003;49:1691-5.
26. Muller S, Martin S, Koenig W, Hanifi-Moghaddam P, Rathmann W, Haastert B, Giani G, Illig T, Thorand B, Kolb H. Impaired glucose tolerance is associated with increased serum concentrations of interleukin 6 and co-regulated acute-phase proteins but not TNF-alpha or its receptors. Diabetologia 2002;45:805-12.
27. Thorand B, Baumert J, Chambless L, Meisinger C, Kolb H, Doring A, Lowel H, Koenig W. Elevated markers of endothelial dysfunction predict type 2 diabetes mellitus in middle-aged men and women from the general population. Arterioscler Thromb Vasc Biol 2006;26:398-405.
28. Herder C, Baumert J, Thorand B, Martin S, Lowel H, Kolb H, Koenig W. Chemokines and incident coronary heart disease: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002. Arterioscler Thromb Vasc Biol 2006;26:2147-52.
29. Herder C, Baumert J, Thorand B, Koenig W, de Jager W, Meisinger C, Illig T, Martin S, Kolb H. Chemokines as risk factors for type 2 diabetes: results from the MONICA/KORA Augsburg study, 1984-2002. Diabetologia 2006;49:921-9.
30. Herder C, Illig T, Baumert J, Muller M, Klopp N, Khuseyinova N, Meisinger C, Martin S, Thorand B, Koenig W. Macrophage migration inhibitory factor (MIF) and risk for coronary heart disease: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002. Atherosclerosis 2008;200:380-8.
31. Barlow WE. Robust variance estimation for the case-cohort design. Biometrics 1994;50:1064-72.
32. Greenland S. Modeling and variable selection in epidemiologic analysis. Am J Public Health 1989;79:340-9.
33. Pandey S, Elliot W. Suppressor variables in social work research: ways to identify in multiple regression models. J Soc Soc Work Res 2010;1:28-40.
34. Niu J, Kolattukudy PE. Role of MCP-1 in cardiovascular disease: molecular mechanisms and clinical implications. Clin Sci 2009;117:95-109.
35. Asberg M, Nygren A, Leopardi R, Rylander G, Peterson U, Wilczek L, Kallmen H, Ekstedt M, Akerstedt T, Lekander M, Ekman R. Novel biochemical markers of psychosocial stress in women. PLoS One2009;4:e3590.
36. Fukuda H, Ichinose T, Kusama T, Sakurai R, Anndow K, Akiyoshi N. Stress assessment in acute care department nurses by measuring interleukin-8. Int Nurs Rev 2008;55:407-11.
37. Rabkin SW. The role of interleukin 18 in the pathogenesis of hypertension-induced vascular disease. Nat Clin Pract Cardiovasc Med 2009;6:192-9.
38. Herder C, Baumert J, Kolb H, Koenig W, Martin S, Thorand B. Circulating levels of interleukin-18 independent of body fat and fat-free mass: results from the MONICA/KORA study. Diabetes Care 2006;29:174-5.
39. Sugama S, Conti B. Interleukin-18 and stress. Brain Res Rev 2008;58: 85-95.
40. Emeny RT, Lacruz ME, Baumert J, Zierer A, von Eisenhart Rothe A, Autenrieth C, Herder C, Koenig W, Thorand B, Ladwig KH. Job strain associated CRP mediated by leisure time physical activity: results from the MONICA/KORA study. Brain Behav Immun 2012;26:1077-84.
41. Franceschi C, Bonafe M, Valensin S, Olivieri F, De Luca M, Ottaviani E, De Benedictis G. Inflamm-aging. An evolutionary perspective on immunosenescence. Ann N Y Acad Sci 2000;908:244-54.
42. Chandola T, Heraclides A, Kumari M. Psychophysiological biomarkers of workplace stressors. Neurosc Biobehav Rev 2010;35:51-7.
43. Chandola T, Britton A, Brunner E, Hemingway H, Malik M, Kumari M, Badrick E, Kivimaki M, Marmot M. Work stress and coronary heart disease: what are the mechanisms? Eur Heart J 2008;29:640-8.
44. Hamer M, Molloy GJ, Stamatakis E. Psychological distress as a risk factor for cardiovascular events: pathophysiological and behavioral mechanisms. J Am Coll Cardiol 2008;52:2156-62.
45. Nabi H, Singh-Manoux A, Shipley M, Gimeno D, Marmot MG, Kivimaki M. Do psychological factors affect inflammation and incident coronary heart disease: the Whitehall II study. Arteriosc Thromb Vasc Biol 2008;28: 1398-406.
46. Herder C, Baumert J, Zierer A, Roden M, Meisinger C, Karakas M, Chambless L, Rathmann W, Peters A, Koenig W, Thorand B. Immuno-logical and cardiometabolic risk factors in the prediction of type 2 diabetes and coronary events: MONICA/KORA Augsburg case-cohort study. PLoS One 2011;6:e19852.
47. Wannamethee SG, Shaper AG, Whincup PH, Walker M. Role of risk factors for major coronary heart disease events with increasing length of follow up. Heart 1999;81:374-9.
48. Hein HO, Suadicani P, Gyntelberg F. Physical fitness or physical activity as a predictor of ischaemic heart disease? A 17-year follow-up in the Copenhagen Male Study. J Intern Med 1992;232:471-9.
49. Wong E, Freiberg M, Tracy R, Kuller L. Epidemiology of cytokines: the Women On the Move through Activity and Nutrition (WOMAN) Study. Am J Epidemiol 2008;168:443-53.
50. Koenig W, Sund M, Frohlich M, Lowel H, Hutchinson WL, Pepys MB. Refinement of the association of serum C-reactive protein concentration and coronary heart disease risk by correction for within-subject variation over time: the MONICA Augsburg studies, 1984 and 1987. Am J Epidemiol 2003;158:357-64.
51. Kraemer HC, Stice E, Kazdin A, Offord D, Kupfer D. How do risk factors work together? Mediators, moderators, and independent, overlapping, and proxy risk factors. Am J Psychiatry 2001;158:848-56.
52. Fagundes CP, Glaser R, Hwang BS, Malarkey WB, Kiecolt-Glaser JK. Depressive symptoms enhance stress-induced inflammatory responses. Brain Behav Immun 2012 doi: 10.1016/j.bbi.2012.05.006.
53. Hackett RA, Hamer M, Endrighi R, Brydon L, Steptoe A. Loneliness and stress-related inflammatory and neuroendocrine responses in older men and women. Psychoneuroendocrinology 2012;37:1801-9.
54. Kivimaki M, Leino-Arjas P, Luukkonen R, Riihimaki H, Vahtera J, Kirjonen J. Work stress and risk of cardiovascular mortality: prospective cohort study of industrial employees. BMJ 2002;325:857.
55. Virtanen M, Ferrie JE, Singh-Manoux A, Shipley MJ, Vahtera J, Marmot MG, Kivimaki M. Overtime work and incident coronary heart disease: the Whitehall II prospective cohort study. Eur Heart J 2010;31:1737-44.
56. Hintsa T, Shipley MJ, Gimeno D, Elovainio M, Chandola T, Jokela M, Keltikangas-Jarvinen L, Vahtera J, Marmot MG, Kivimaki M. Do pre-employment influences explain the association between psychosocial factors at work and coronary heart disease? The Whitehall II study. Occup Environ Med 2010;67:330-4.