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Volumn 63, Issue 1, 2013, Pages 34-41

CD4 count slope and mortality in HIV-infected patients on antiretroviral therapy: Multicohort analysis from South Africa

Author keywords

antiretroviral therapy; CD4 count slope; HIV; HIV RNA; mortality; resource limited setting

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; VIRUS RNA;

EID: 84876286691     PISSN: 15254135     EISSN: 10779450     Source Type: Journal    
DOI: 10.1097/QAI.0b013e318287c1fe     Document Type: Article
Times cited : (22)

References (51)
  • 2
    • 0030070991 scopus 로고    scopus 로고
    • Prognosis in HIV-1 infection predicted by the quantity of virus in plasma
    • Mellors JW, Rinaldo CR Jr, Gupta P, et al. Prognosis in HIV-1 infection predicted by the quantity of virus in plasma. Science. 1996;272:1167-1170.
    • (1996) Science. , vol.272 , pp. 1167-1170
    • Mellors, J.W.1    Rinaldo, Jr.C.R.2    Gupta, P.3
  • 3
    • 33749079234 scopus 로고    scopus 로고
    • Predictive value of plasma HIV RNA level on rate of CD4 T-cell decline in untreated HIV infection
    • Rodriguez B, Sethi AK, Cheruvu VK, et al. Predictive value of plasma HIV RNA level on rate of CD4 T-cell decline in untreated HIV infection. JAMA. 2006;296:1498-1506.
    • (2006) JAMA , vol.296 , pp. 1498-1506
    • Rodriguez, B.1    Sethi, A.K.2    Cheruvu, V.K.3
  • 4
    • 33846439783 scopus 로고    scopus 로고
    • CD4+ cell count 6 years after commencement of highly active antiretroviral therapy in persons with sustained virologic suppression
    • Moore RD, Keruly JC. CD4+ cell count 6 years after commencement of highly active antiretroviral therapy in persons with sustained virologic suppression. Clin Infect Dis. 2007;44:441-446.
    • (2007) Clin Infect Dis. , vol.44 , pp. 441-446
    • Moore, R.D.1    Keruly, J.C.2
  • 5
    • 58749087048 scopus 로고    scopus 로고
    • The absence of CD4+ T cell count recovery despite receipt of virologically suppressive highly active antiretroviral therapy: Clinical risk, immunological gaps, and therapeutic options
    • Gazzola L, Tincati C, Bellistri GM, et al. The absence of CD4+ T cell count recovery despite receipt of virologically suppressive highly active antiretroviral therapy: clinical risk, immunological gaps, and therapeutic options. Clin Infect Dis. 2009;48:328-337.
    • (2009) Clin Infect Dis. , vol.48 , pp. 328-337
    • Gazzola, L.1    Tincati, C.2    Bellistri, G.M.3
  • 6
    • 34247639428 scopus 로고    scopus 로고
    • Discordant responses to potent antiretroviral treatment in previously naive HIV-1-infected adults initiating treatment in resource-constrained countries: The antiretroviral therapy in low-income countries (ART-LINC) collaboration
    • Tuboi SH, Brinkhof MW, Egger M, et al. Discordant responses to potent antiretroviral treatment in previously naive HIV-1-infected adults initiating treatment in resource-constrained countries: the antiretroviral therapy in low-income countries (ART-LINC) collaboration. J Acquir Immune Defic Syndr. 2007;45:52-59.
    • (2007) J Acquir Immune Defic Syndr. , vol.45 , pp. 52-59
    • Tuboi, S.H.1    Brinkhof, M.W.2    Egger, M.3
  • 7
    • 53549099373 scopus 로고    scopus 로고
    • Evaluation of the WHO criteria for antiretroviral treatment failure among adults in South Africa
    • Mee P, Fielding KL, Charalambous S, et al. Evaluation of the WHO criteria for antiretroviral treatment failure among adults in South Africa. AIDS. 2008;22:1971-1977.
    • (2008) AIDS , vol.22 , pp. 1971-1977
    • Mee, P.1    Fielding, K.L.2    Charalambous, S.3
  • 8
    • 81855172463 scopus 로고    scopus 로고
    • Immunologic criteria are poor predictors of virologic outcome: Implications for HIV treatment monitoring in resource-limited settings
    • Rawizza HE, Chaplin B, Meloni ST, et al. Immunologic criteria are poor predictors of virologic outcome: implications for HIV treatment monitoring in resource-limited settings. Clin Infect Dis. 2011;53:1283-1290.
    • (2011) Clin Infect Dis. , vol.53 , pp. 1283-1290
    • Rawizza, H.E.1    Chaplin, B.2    Meloni, S.T.3
  • 9
    • 70349238935 scopus 로고    scopus 로고
    • Accuracy of WHO CD4 cell count criteria for virological failure of antiretroviral therapy
    • Keiser O, MacPhail P, Boulle A, et al. Accuracy of WHO CD4 cell count criteria for virological failure of antiretroviral therapy. Trop Med Int Health. 2009;14:1220-1225.
    • (2009) Trop Med Int Health. , vol.14 , pp. 1220-1225
    • Keiser, O.1    MacPhail, P.2    Boulle, A.3
  • 10
    • 0029963323 scopus 로고    scopus 로고
    • Immunopathogenic mechanisms of HIV infection
    • Fauci AS, Pantaleo G, Stanley S, et al. Immunopathogenic mechanisms of HIV infection. Ann Intern Med. 1996;124:654-663.
    • (1996) Ann Intern Med. , vol.124 , pp. 654-663
    • Fauci, A.S.1    Pantaleo, G.2    Stanley, S.3
  • 11
    • 0029045298 scopus 로고
    • Distribution of CD4+ T lymphocytes at diagnosis of acquired immunodeficiency syndrome-defining and other human immunodeficiency virus-related illnesses. The Adult and Adolescent Spectrum of HIV Disease Project Group
    • Hanson DL, Chu SY, Farizo KM, et al. Distribution of CD4+ T lymphocytes at diagnosis of acquired immunodeficiency syndrome-defining and other human immunodeficiency virus-related illnesses. The Adult and Adolescent Spectrum of HIV Disease Project Group. Arch Intern Med. 1995;155:1537-1542.
    • (1995) Arch Intern Med. , vol.155 , pp. 1537-1542
    • Hanson, D.L.1    Chu, S.Y.2    Farizo, K.M.3
  • 12
    • 3342924015 scopus 로고    scopus 로고
    • Absolute CD4 vs. CD4 percentage for predicting the risk of opportunistic illness in HIV infection
    • Gebo KA, Gallant JE, Keruly JC, et al. Absolute CD4 vs. CD4 percentage for predicting the risk of opportunistic illness in HIV infection. J Acquir Immune Defic Syndr. 2004;36:1028-1033.
    • (2004) J Acquir Immune Defic Syndr. , vol.36 , pp. 1028-1033
    • Gebo, K.A.1    Gallant, J.E.2    Keruly, J.C.3
  • 13
    • 33745003258 scopus 로고    scopus 로고
    • CD4-guided structured antiretroviral treatment interruption strategy in HIV-infected adults in west Africa (Tri-vacan ANRS 1269 trial): A randomised trial
    • Danel C, Moh R, Minga A, et al. CD4-guided structured antiretroviral treatment interruption strategy in HIV-infected adults in west Africa (Tri-vacan ANRS 1269 trial): a randomised trial. Lancet. 2006;367:1981-1989.
    • (2006) Lancet. , vol.367 , pp. 1981-1989
    • Danel, C.1    Moh, R.2    Minga, A.3
  • 14
    • 34249986747 scopus 로고    scopus 로고
    • Prognostic value of HIV-1 RNA CD4 cell count and CD4 Cell count slope for progression to AIDS and death in untreated HIV-1 infection
    • Mellors JW, Margolick JB, Phair JP, et al. Prognostic value of HIV-1 RNA, CD4 cell count, and CD4 Cell count slope for progression to AIDS and death in untreated HIV-1 infection. JAMA. 2007;297:2349-2350.
    • (2007) JAMA , vol.297 , pp. 2349-2350
    • Mellors, J.W.1    Margolick, J.B.2    Phair, J.P.3
  • 15
    • 84862215127 scopus 로고    scopus 로고
    • CD4 cell count and the risk of AIDS or death in HIV-infected adults on combination antiretroviral therapy with a suppressed viral load: A longitudinal cohort study from COHERE
    • Young J, Psichogiou M, Meyer L, et al. CD4 cell count and the risk of AIDS or death in HIV-infected adults on combination antiretroviral therapy with a suppressed viral load: a longitudinal cohort study from COHERE. PLoS Med. 2012;9:e1001194.
    • (2012) PLoS Med. , vol.9
    • Young, J.1    Psichogiou, M.2    Meyer, L.3
  • 16
    • 77953913058 scopus 로고    scopus 로고
    • Factors associated with specific causes of death amongst HIV-positive individuals in the D:A:D Study
    • Smith C, Sabin CA, Lundgren JD, et al; and Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) Study Group. Factors associated with specific causes of death amongst HIV-positive individuals in the D:A:D Study. AIDS. 2010;24:1537-1548.
    • (2010) AIDS , vol.24 , pp. 1537-1548
    • Smith, C.1    Sabin, C.A.2    Lundgren, J.D.3
  • 17
    • 70450178532 scopus 로고    scopus 로고
    • Monitoring the South African National Antiretroviral Treatment Programme 2003-2007: The IeDEA Southern Africa collaboration
    • Cornell M, Technau K, Fairall L, et al. Monitoring the South African National Antiretroviral Treatment Programme, 2003-2007: the IeDEA Southern Africa collaboration. S Afr Med J. 2009;99:653-660.
    • (2009) S Afr Med J. , vol.99 , pp. 653-660
    • Cornell, M.1    Technau, K.2    Fairall, L.3
  • 18
    • 84867592540 scopus 로고    scopus 로고
    • Cohort profile: The international epidemiological databases to evaluate AIDS (IeDEA) in sub-Saharan Africa
    • Egger M, Ekouevi DK, Williams C, et al. Cohort profile: the international epidemiological databases to evaluate AIDS (IeDEA) in sub-Saharan Africa. Int J Epidemiol. 2012;41:1256-1264.
    • (2012) Int J Epidemiol. , vol.41 , pp. 1256-1264
    • Egger, M.1    Ekouevi, D.K.2    Williams, C.3
  • 19
    • 42449152330 scopus 로고    scopus 로고
    • Large-scale affordable PanLeucogated CD4+ testing with proactive internal and external quality assessment: In support of the South African national comprehensive care, treatment and management programme for HIV and AIDS
    • Glencross DK, Janossy G, Coetzee LM, et al. Large-scale affordable PanLeucogated CD4+ testing with proactive internal and external quality assessment: in support of the South African national comprehensive care, treatment and management programme for HIV and AIDS. Cytometry B Clin Cytom. 2008;74(suppl 1):S40-S51.
    • (2008) Cytometry B Clin Cytom. , vol.74 , Issue.SUPPL. 1
    • Glencross, D.K.1    Janossy, G.2    Coetzee, L.M.3
  • 20
    • 77956229669 scopus 로고    scopus 로고
    • Temporal changes in programme outcomes among adult patients initiating antiretroviral therapy across South Africa, 2002-2007
    • Cornell M, Grimsrud A, Fairall L, et al. Temporal changes in programme outcomes among adult patients initiating antiretroviral therapy across South Africa, 2002-2007. AIDS. 2010;24:2263-2270.
    • (2010) AIDS , vol.24 , pp. 2263-2270
    • Cornell, M.1    Grimsrud, A.2    Fairall, L.3
  • 21
    • 17344371054 scopus 로고    scopus 로고
    • Variability and prognostic values of virologic and CD4 cell measures in human immunodeficiency virus type 1-infected patients with 200-500 CD4 cells/mm(3) (ACTG 175). AIDS Clinical Trials Group Protocol 175 Team
    • Lathey JL, Hughes MD, Fiscus SA, et al. Variability and prognostic values of virologic and CD4 cell measures in human immunodeficiency virus type 1-infected patients with 200-500 CD4 cells/mm(3) (ACTG 175). AIDS Clinical Trials Group Protocol 175 Team. J Infect Dis. 1998;177:617-624.
    • (1998) J Infect Dis. , vol.177 , pp. 617-624
    • Lathey, J.L.1    Hughes, M.D.2    Fiscus, S.A.3
  • 22
    • 33644835815 scopus 로고    scopus 로고
    • Mortality of HIV-1-infected patients in the first year of antiretroviral therapy: Comparison between low-income and high-income countries
    • Braitstein P, Brinkhof MW, Dabis F, et al. Mortality of HIV-1-infected patients in the first year of antiretroviral therapy: comparison between low-income and high-income countries. Lancet. 2006;367:817-824.
    • (2006) Lancet. , vol.367 , pp. 817-824
    • Braitstein, P.1    Brinkhof, M.W.2    Dabis, F.3
  • 23
    • 77949382892 scopus 로고    scopus 로고
    • Using vital registration data to update mortality among patients lost to follow-up from ART programmes: Evidence from the Themba Lethu Clinic South Africa
    • Fox MP, Brennan A, Maskew M, et al. Using vital registration data to update mortality among patients lost to follow-up from ART programmes: evidence from the Themba Lethu Clinic, South Africa. Trop Med Int Health. 2010;15:405-413.
    • (2010) Trop Med Int Health. , vol.15 , pp. 405-413
    • Fox, M.P.1    Brennan, A.2    Maskew, M.3
  • 24
    • 48749124902 scopus 로고    scopus 로고
    • Sampling-based approach to determining outcomes of patients lost to follow-up in antiretroviral therapy scale-up programs in Africa
    • Geng EH, Emenyonu N, Bwana MB, et al. Sampling-based approach to determining outcomes of patients lost to follow-up in antiretroviral therapy scale-up programs in Africa. JAMA. 2008;300:506-507.
    • (2008) JAMA , vol.300 , pp. 506-507
    • Geng, E.H.1    Emenyonu, N.2    Bwana, M.B.3
  • 25
    • 45849090789 scopus 로고    scopus 로고
    • Overestimates of survival after HAART: Implications for global scale-up efforts
    • Bisson GP, Gaolathe T, Gross R, et al. Overestimates of survival after HAART: implications for global scale-up efforts. PLoS One. 2008;3:e1725.
    • (2008) PLoS One. , vol.3
    • Bisson, G.P.1    Gaolathe, T.2    Gross, R.3
  • 26
    • 77649266974 scopus 로고    scopus 로고
    • Seven-year experience of a primary care antiretroviral treatment programme in Khayelitsha South Africa
    • Boulle A, Van CG, Hilderbrand K, et al. Seven-year experience of a primary care antiretroviral treatment programme in Khayelitsha, South Africa. AIDS. 2010;24:563-572.
    • (2010) AIDS , vol.24 , pp. 563-572
    • Boulle, A.1    Van, C.G.2    Hilderbrand, K.3
  • 28
    • 68249114452 scopus 로고    scopus 로고
    • Multiple imputation for missing data in epidemiological and clinical research: Potential and pitfalls
    • Sterne JA, White IR, Carlin JB, et al. Multiple imputation for missing data in epidemiological and clinical research: potential and pitfalls. BMJ. 2009;338:b2393.
    • (2009) BMJ. , vol.338
    • Sterne, J.A.1    White, I.R.2    Carlin, J.B.3
  • 29
    • 77954332545 scopus 로고    scopus 로고
    • What to do about missing values in time-series cross-section data
    • Honaker J. What to do about missing values in time-series cross-section data. Am J Pol Sci. 2010;54:561-581.
    • (2010) Am J Pol Sci. , vol.54 , pp. 561-581
    • Honaker, J.1
  • 30
    • 0030539070 scopus 로고    scopus 로고
    • Multiple imputation after 18+ years
    • Rubin DB. Multiple imputation after 18+ years. J Am Stat Assoc. 1996; 91:473-489.
    • (1996) J Am Stat Assoc. , vol.91 , pp. 473-489
    • Rubin, D.B.1
  • 31
    • 33750961260 scopus 로고    scopus 로고
    • Changes in the slope of the CD4 cell count increase after initiation of potent antiretroviral treatment
    • Bosch RJ, Wang R, Vaida F, et al. Changes in the slope of the CD4 cell count increase after initiation of potent antiretroviral treatment. J Acquir Immune Defic Syndr. 2006;43:433-435.
    • (2006) J Acquir Immune Defic Syndr. , vol.43 , pp. 433-435
    • Bosch, R.J.1    Wang, R.2    Vaida, F.3
  • 32
    • 80054921123 scopus 로고    scopus 로고
    • Changing predictors of mortality over time from cART start: Implications for care
    • Hoffmann CJ, Fielding KL, Johnston V, et al. Changing predictors of mortality over time from cART start: implications for care. JAIDS 2011; 58:269-276.
    • (2011) JAIDS , vol.58 , pp. 269-276
    • Hoffmann, C.J.1    Fielding, K.L.2    Johnston, V.3
  • 33
    • 59849099091 scopus 로고    scopus 로고
    • Changing mortality risk associated with CD4 cell response to antiretroviral therapy in South Africa
    • Lawn SD, Little F, Bekker LG, et al. Changing mortality risk associated with CD4 cell response to antiretroviral therapy in South Africa. AIDS. 2009;23:335-342.
    • (2009) AIDS , vol.23 , pp. 335-342
    • Lawn, S.D.1    Little, F.2    Bekker, L.G.3
  • 34
    • 36348986088 scopus 로고    scopus 로고
    • Incidence and determinants of mortality and morbidity following early antiretroviral therapy initiation in HIV-infected adults in West Africa
    • Moh R, Danel C, Messou E, et al. Incidence and determinants of mortality and morbidity following early antiretroviral therapy initiation in HIV-infected adults in West Africa. AIDS. 2007;21:2483-2491.
    • (2007) AIDS , vol.21 , pp. 2483-2491
    • Moh, R.1    Danel, C.2    Messou, E.3
  • 35
    • 33751257486 scopus 로고    scopus 로고
    • Risk factors for high early mortality in patients on antiretroviral treatment in a rural district of Malawi
    • Zachariah R, Fitzgerald M, Massaquoi M, et al. Risk factors for high early mortality in patients on antiretroviral treatment in a rural district of Malawi. AIDS. 2006;20:2355-2360.
    • (2006) AIDS , vol.20 , pp. 2355-2360
    • Zachariah, R.1    Fitzgerald, M.2    Massaquoi, M.3
  • 36
    • 77955566935 scopus 로고    scopus 로고
    • Prognosis of patients with HIV-1 infection starting antiretroviral therapy in sub-Saharan Africa: A collaborative analysis of scale-up programmes
    • May M, Boulle A, Phiri S, et al. Prognosis of patients with HIV-1 infection starting antiretroviral therapy in sub-Saharan Africa: a collaborative analysis of scale-up programmes. Lancet. 2010;376:449-457.
    • (2010) Lancet. , vol.376 , pp. 449-457
    • May, M.1    Boulle, A.2    Phiri, S.3
  • 37
    • 66149122978 scopus 로고    scopus 로고
    • Mortality of HIV-infected patients starting antiretroviral therapy in sub-Saharan Africa: Comparison with HIV-unrelated mortality
    • Brinkhof MW, Boulle A, Weigel R, et al. Mortality of HIV-infected patients starting antiretroviral therapy in sub-Saharan Africa: comparison with HIV-unrelated mortality. PLoS Med. 2009;6:e1000066.
    • (2009) PLoS Med. , vol.6
    • Brinkhof, M.W.1    Boulle, A.2    Weigel, R.3
  • 38
    • 80355129311 scopus 로고    scopus 로고
    • Association of low level viremia with inflammation and mortality in HIV-infected adults
    • Eastburn A, Scherzer R, Zolopa AR, et al. Association of low level viremia with inflammation and mortality in HIV-infected adults. PLoS One. 2011;6:e26320.
    • (2011) PLoS One. , vol.6
    • Eastburn, A.1    Scherzer, R.2    Zolopa, A.R.3
  • 39
    • 0035504938 scopus 로고    scopus 로고
    • Surrogate markers for disease progression in treated HIV infection
    • Ghani AC, de WF, Ferguson NM, et al. Surrogate markers for disease progression in treated HIV infection. J Acquir Immune Defic Syndr. 2001;28:226-231.
    • (2001) J Acquir Immune Defic Syndr. , vol.28 , pp. 226-231
    • Ghani, A.C.1    De, W.F.2    Ferguson, N.M.3
  • 40
    • 0036721238 scopus 로고    scopus 로고
    • Factors associated with mortality in human immunodeficiency virus type 1-infected adults initiating protease inhibitor-containing therapy: Role of education level and of early transaminase level elevation (APROCO-ANRS EP11 study). The Antipro-teases Cohorte Agence Nationale de Recherches sur le SIDA EP 11 study
    • Lewden C, Raffi F, Cuzin L, et al. Factors associated with mortality in human immunodeficiency virus type 1-infected adults initiating protease inhibitor-containing therapy: role of education level and of early transaminase level elevation (APROCO-ANRS EP11 study). The Antipro-teases Cohorte Agence Nationale de Recherches sur le SIDA EP 11 study. J Infect Dis. 2002;186:710-714.
    • (2002) J Infect Dis. , vol.186 , pp. 710-714
    • Lewden, C.1    Raffi, F.2    Cuzin, L.3
  • 41
    • 3042740596 scopus 로고    scopus 로고
    • Predictors of trend in CD4-positive T-cell count and mortality among HIV-1-infected individuals with virological failure to all three antiretroviral-drug classes
    • Ledergerber B, Lundgren JD, Walker AS, et al. Predictors of trend in CD4-positive T-cell count and mortality among HIV-1-infected individuals with virological failure to all three antiretroviral-drug classes. Lancet. 2004;364:51-62.
    • (2004) Lancet. , vol.364 , pp. 51-62
    • Ledergerber, B.1    Lundgren, J.D.2    Walker, A.S.3
  • 42
    • 0037080037 scopus 로고    scopus 로고
    • A clinically prognostic scoring system for patients receiving highly active antiretroviral therapy: Results from the EuroSIDA study
    • Lundgren JD, Mocroft A, Gatell JM, et al. A clinically prognostic scoring system for patients receiving highly active antiretroviral therapy: results from the EuroSIDA study. J Infect Dis. 2002;185:178-187.
    • (2002) J Infect Dis. , vol.185 , pp. 178-187
    • Lundgren, J.D.1    Mocroft, A.2    Gatell, J.M.3
  • 43
    • 68049123174 scopus 로고    scopus 로고
    • Uncontrolled viral replication as a risk factor for non-AIDS severe clinical events in HIV-infected patients on long-term antiretroviral therapy: APROCO/COPILOTE (ANRS CO8) cohort study
    • Ferry T, Raffi F, Collin-Filleul F, et al. Uncontrolled viral replication as a risk factor for non-AIDS severe clinical events in HIV-infected patients on long-term antiretroviral therapy: APROCO/COPILOTE (ANRS CO8) cohort study. J Acquir Immune Defic Syndr. 2009;51:407-415.
    • (2009) J Acquir Immune Defic Syndr. , vol.51 , pp. 407-415
    • Ferry, T.1    Raffi, F.2    Collin-Filleul, F.3
  • 44
    • 80855132759 scopus 로고    scopus 로고
    • Fatal and nonfatal AIDS and non-AIDS events in HIV-1-positive individuals with high CD4 cell counts according to viral load strata
    • Reekie J, Gatell JM, Yust I, et al. Fatal and nonfatal AIDS and non-AIDS events in HIV-1-positive individuals with high CD4 cell counts according to viral load strata. AIDS. 2011;25:2259-2268.
    • (2011) AIDS , vol.25 , pp. 2259-2268
    • Reekie, J.1    Gatell, J.M.2    Yust, I.3
  • 45
    • 1042300003 scopus 로고    scopus 로고
    • The prognostic importance of changes in CD4+ cell count and HIV-1 RNA level in women after initiating highly active antiretroviral therapy
    • Anastos K, Barron Y, Cohen MH, et al. The prognostic importance of changes in CD4+ cell count and HIV-1 RNA level in women after initiating highly active antiretroviral therapy. Ann Intern Med. 2004; 140:256-264.
    • (2004) Ann Intern Med. , vol.140 , pp. 256-264
    • Anastos, K.1    Barron, Y.2    Cohen, M.H.3
  • 46
    • 77956645721 scopus 로고    scopus 로고
    • Relationship between CD4+ T-cell counts/HIV-1 RNA plasma viral load and AIDS-defining events among persons followed in the ACTG longitudinal linked randomized trials study
    • Smurzynski M, Wu K, Benson CA, et al. Relationship between CD4+ T-cell counts/HIV-1 RNA plasma viral load and AIDS-defining events among persons followed in the ACTG longitudinal linked randomized trials study. J Acquir Immune Defic Syndr. 2010;55:117-127.
    • (2010) J Acquir Immune Defic Syndr. , vol.55 , pp. 117-127
    • Smurzynski, M.1    Wu, K.2    Benson, C.A.3
  • 47
    • 77952436164 scopus 로고    scopus 로고
    • Risk of pneumocystosis after early discontinuation of prophylaxis among HIV-infected patients receiving highly active antiretroviral therapy
    • Cheng CY, Chen MY, Hsieh SM, et al. Risk of pneumocystosis after early discontinuation of prophylaxis among HIV-infected patients receiving highly active antiretroviral therapy. BMC Infect Dis. 2010;10:126.
    • (2010) BMC Infect Dis. , vol.10 , pp. 126
    • Cheng, C.Y.1    Chen, M.Y.2    Hsieh, S.M.3
  • 48
    • 83455255609 scopus 로고    scopus 로고
    • Discontinuation of Pneumocystis jirovecii pneumonia prophylaxis with CD4 count, 200 cells/microL and virologic suppression: A systematic review
    • Costiniuk CT, Fergusson DA, Doucette S, et al. Discontinuation of Pneumocystis jirovecii pneumonia prophylaxis with CD4 count, 200 cells/microL and virologic suppression: a systematic review. PLoS One. 2011;6:e28570.
    • (2011) PLoS One. , vol.6
    • Costiniuk, C.T.1    Fergusson, D.A.2    Doucette, S.3
  • 49
    • 0041326880 scopus 로고    scopus 로고
    • Continued CD4 cell count increases in HIV-infected adults experiencing 4 years of viral suppression on antiretroviral therapy
    • Hunt PW, Deeks SG, Rodriguez B, et al. Continued CD4 cell count increases in HIV-infected adults experiencing 4 years of viral suppression on antiretroviral therapy. AIDS. 2003;17:1907-1915.
    • (2003) AIDS , vol.17 , pp. 1907-1915
    • Hunt, P.W.1    Deeks, S.G.2    Rodriguez, B.3
  • 50
    • 3042740596 scopus 로고    scopus 로고
    • Predictors of trend in CD4-positive T-cell count and mortality among HIV-1-infected individuals with virological failure to all three antiretroviral-drug classes
    • Ledergerber B, Lundgren JD, Walker AS, et al. Predictors of trend in CD4-positive T-cell count and mortality among HIV-1-infected individuals with virological failure to all three antiretroviral-drug classes. Lancet. 2004;364:51-62.
    • (2004) Lancet. , vol.364 , pp. 51-62
    • Ledergerber, B.1    Lundgren, J.D.2    Walker, A.S.3
  • 51
    • 79959792182 scopus 로고    scopus 로고
    • Association of age with mortality and virological and immunological response to antiretroviral therapy in rural South African adults
    • Mutevedzi PC, Lessells RJ, Rodger AJ, et al. Association of age with mortality and virological and immunological response to antiretroviral therapy in rural South African adults. PLoS One. 2011;6:e21795.
    • (2011) PLoS One. , vol.6
    • Mutevedzi, P.C.1    Lessells, R.J.2    Rodger, A.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.