Surrogate markers for disease progression in treated HIV infection

Journal of Acquired Immune Deficiency Syndromes

Volumn 28, Issue 3, 2001, Pages 226-231

  Ghani, Azra C ^a   De Wolf, Frank ^b   Ferguson, Neil M ^a   Donnelly, Christl A ^a   Coutinho, Roel ^b   Miedema, Frank ^b   Goudsmit, Jaap ^b   Anderson, Roy M ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Antiretroviral therapy; Cohort study; Disease progression; HIV 1; Surrogate markers

Indexed keywords

ANTIRETROVIRUS AGENT; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; VIRUS RNA;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; DISEASE COURSE; DISEASE MARKER; HOMOSEXUALITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; SEROCONVERSION; TREATMENT OUTCOME;

EID: 0035504938     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042560-200111010-00004     Document Type: Article

References (27)

1. + T cell homeostasis and function in advanced HIV disease
2. Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: A composite of redistribution and proliferation
3. The relation of virologic and immunologic markers to clinical outcomes after nucleoside therapy in HIV-1 infected adults
4. Use of changes in plasma levels of Human Immunodeficiency Virus type 1 RNA to assess the clinical benefit of antiretroviral therapy
5. Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection
6. Viral dynamics in HIV-infection
7. Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy
8. Persistence of HIV-1 transcription in peripheral blood mononuclear cells in patients receiving potent antiretroviral therapy
9. Numbers of CD4+ cells and the levels of core antigens of and antibodies to the human immunodeficiency virus as predictors of AIDS among seropositive homosexual men
10. The cumulative risk of AIDS as the CD4 lymphocyte count declines
11. Early predictors of survival in symptomatic HIV-infected persons treated with high-dose zidovudine
12. Quantitation of HIV-1 RNA in plasma predicts outcome after seroconversion
13. Prognosis in HIV-1 infection predicted by the quantity of virus in plasma
14. Changes in plasma HIV-1 RNA and CD4+ lymphocyte counts and the risk of progression to AIDS
15. + T-cell count and function: Markers with reciprocal predictive value over time after seroconversion
16. Early and late HIV-1 RNA level and its association with other markers and disease progression in long-term AIDS-free homosexual men
17. HIV-1 RNA levels and the development of clinical disease
18. Prognostic value of plasma human immunodeficiency virus type 1 (HIV-1) RNA levels in patients with advanced HIV-1 disease and little or no prior zidovudine therapy
19. Statistical issues for HIV surrogate endpoints: Point/counterpoint
20. Longitudinal data analysis for discrete and continuous outcomes
21. Longitudinal data analysis using generalized linear models
22. Proportional hazards models with covariates subject to measurement error
23. Estimating risks of progressing to AIDS when covariates are measured with error
24. Failure of T-cell homeostasis preceding AIDS in HIV-1 infection. The Multicenter AIDS Cohort Study