Accelerated partial-breast irradiation: The current state of our knowledge

ONCOLOGY (United States)

Volumn 27, Issue 4, 2013, Pages

  Shaitelman, Simona F ^a   Kim, Leonard H ^b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTON;

ACCELERATED PARTIAL BREAST IRRADIATION; ALTERNATIVE MEDICINE; BRACHYTHERAPY; BREAST CANCER; BREAST PARENCHYMA; CANCER CONTROL; CANCER RADIOTHERAPY; CANCER RECURRENCE; COHORT ANALYSIS; CONSERVATIVE TREATMENT; DOSE RESPONSE; EARLY CANCER; ELECTRON THERAPY; EXTERNAL BEAM RADIOTHERAPY; FOLLOW UP; HEALTH CARE COST; HUMAN; INTENSITY MODULATED RADIATION THERAPY; INTERMETHOD COMPARISON; INTRAOPERATIVE RADIOTHERAPY; MASTECTOMY; MONOTHERAPY; MULTICATHETER INTERSTITIAL BRACHYTHERAPY; OVERALL SURVIVAL; PAIN; PARENCHYMA; PARTIAL MASTECTOMY; PATIENT ATTITUDE; PATIENT SATISFACTION; PHASE 2 CLINICAL TRIAL (TOPIC); POPULATION RESEARCH; POSTOPERATIVE INFECTION; PRACTICE GUIDELINE; PROFESSIONAL KNOWLEDGE; QUALITY OF LIFE; RADIATION DOSE; RADIATION DOSE DISTRIBUTION; RADIATION INJURY; RECURRENCE RISK; REVIEW; RISK BENEFIT ANALYSIS; SEGMENTAL MASTECTOMY; SKIN TOXICITY; TREATMENT DURATION; TREATMENT OUTCOME; WHOLE BREAST IRRADIATION;

EID: 84876274242     PISSN: 08909091     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (74)

1. Fisher B, Anderson S, Bryant J, et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med. 2002;347:1233-41.
2. Darby S, McGale P, Correa C, et al. Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials. Lancet. 2011;378:1707-16.
3. Veronesi U, Marubini E, Mariani L, et al. Radiotherapy after breast-conserving surgery in small breast carcinoma: long-term results of a randomized trial. Ann Oncol. 2001;12:997-1003.
4. Liljegren G, Holmberg L, Bergh J, et al. 10-Year results after sector resection with or without postoperative radiotherapy for stage I breast cancer: a randomized trial. J Clin Oncol. 1999;17:2326-33.
5. Mukesh M, Harris E, Jena R, et al. Relationship between irradiated breast volume and late normal tissue complications: a systematic review. Radiother Oncol. 2012;104:1-10.
6. Kawase E, Karasawa K, Shimotsu S, et al. Estimation of anxiety and depression in patients with early stage breast cancer before and after radiation therapy. Breast Cancer. 2012;19:147-52.
7. Whelan TJ, Levine M, Julian J, et al. The effects of radiation therapy on quality of life of women with breast carcinoma: results of a randomized trial. Ontario Clinical Oncology Group. Cancer. 2000;88:2260-6.
8. Lazovich DA, White E, Thomas DB, Moe RE. Underutilization of breast-conserving surgery and radiation therapy among women with stage I or II breast cancer. JAMA. 1991;266:3433-8.
9. Farrow DC, Hunt WC, Samet JM. Geographic variation in the treatment of localized breast cancer. N Engl J Med. 1992;326:1097-101.
10. Athas WF, Adams-Cameron M, Hunt WC, et al. Travel distance to radiation therapy and receipt of radiotherapy following breast-conserving surgery. J Natl Cancer Inst. 2000;92:269-71.
11. Ma AM, Barone J, Wallis AE, et al. Noncompliance with adjuvant radiation, chemotherapy, or hormonal therapy in breast cancer patients. Am J Surg. 2008;196:500-4.
12. McCarthy EP, Ngo LH, Roetzheim RG, et al. Disparities in breast cancer treatment and survival for women with disabilities. Ann Intern Med. 2006;145:637-45.
13. Suh WW, Pierce LJ, Vicini FA, Hayman JA. A cost comparison analysis of partial versus whole-breast irradiation after breast-conserving surgery for early-stage breast cancer. Int J Radiat Oncol Biol Phys. 2005;62:790-6.
14. Sher DJ, Wittenberg E, Suh WW, et al. Partial-breast irradiation versus whole-breast irradiation for early-stage breast cancer: a cost-effectiveness analysis. Int J Radiat Oncol Biol Phys. 2009;74:440-6.
15. Lanni T, Keisch M, Shah C, et al. A cost comparison analysis of adjuvant radiation therapy techniques after breast-conserving surgery. Breast J. 2013;19:162-7.
16. Shah C, Lanni TB, Saini H, et al. Cost-efficacy of acceleration partial-breast irradiation compared with whole-breast irradiation. Breast Cancer Res Treat. 2013;138:127-35.
17. White JR, Winter KA, Kuske RR, et al. Long-term outcome from RTOG 95-17: a phase I/II study of accelerated partial breast irradiation (APBI) with multicatheter brachytherapy (MCT) following lumpectomy for early-stage breast cancer. J Clin Oncol. 2012;30(Suppl 27):Abstr 147.
18. Polgar C, Major T, Fodor J, et al, eds. Breast-conserving therapy with partial or whole breast RT: 10-year results of the Budapest randomized trial. World Congress of Brachytherapy; 2012; Barcelona, Spain.
19. Hattangadi JA, Powell SN, MacDonald SM, et al. Accelerated partial breast irradiation with low-dose-rate interstitial implant brachytherapy after wide local excision: 12-year outcomes from a prospective trial. Int J Radiat Oncol Biol Phys. 2012;83:791-800.
20. Strnad V, Hildebrandt G, Potter R, et al. Accelerated partial breast irradiation: 5-year results of the German-Austrian multicenter phase II trial using interstitial multicatheter brachytherapy alone after breast-conserving surgery. Int J Radiat Oncol Biol Phys. 2011;80:17-24.
21. Chen PY, Vicini FA, Benitez P, et al. Long-term cosmetic results and toxicity after accelerated partial-breast irradiation: a method of radiation delivery by interstitial brachytherapy for the treatment of early-stage breast carcinoma. Cancer. 2006;106:991-9.
22. Polgar C, Sulyok Z, Fodor J, et al. Sole brachytherapy of the tumor bed after conservative surgery for T1 breast cancer: five-year results of a phase I-II study and initial findings of a randomized phase III trial. J Surg Oncol. 2002;80:121-8; discussion 29.
23. Arthur DW, Vicini FA, Todor DA, et al. Improvements in critical dosimetric endpoints using the Contura multilumen balloon breast brachytherapy catheter to deliver accelerated partial breast irradiation: preliminary dosimetric findings of a phase IV trial. Int J Radiat Oncol Biol Phys. 2011;79:26-33.
24. Smith GL, Xu Y, Buchholz TA, et al. Brachytherapy for accelerated partial-breast irradiation: a rapidly emerging technology in breast cancer care. J Clin Oncol. 2011;29:157-65.
25. Vicini F, Beitsch P, Quiet C, et al. Five-year analysis of treatment efficacy and cosmesis by the American Society of Breast Surgeons MammoSite Breast Brachytherapy Registry Trial in patients treated with accelerated partial breast irradiation. Int J Radiat Oncol Biol Phys. 2011;79:808-17.
26. Khan AJ, Arthur D, Vicini F, et al. Six-year analysis of treatment-related toxicities in patients treated with accelerated partial breast irradiation on the American Society of Breast Surgeons MammoSite Breast Brachytherapy registry trial. Ann Surg Oncol. 2012;19:1477-83.
27. Smith GL, Xu Y, Buchholz TA, et al. Association between treatment with brachytherapy vs whole-breast irradiation and subsequent mastectomy, complications, and survival among older women with invasive breast cancer. JAMA. 2012;307:1827-37.
28. Presley CJ, Soulos PR, Herrin J, et al. Patterns of use and short-term complications of breast brachytherapy in the national Medicare population from 2008-2009. J Clin Oncol. 2012;30:4302-7.
29. Abbott AM, Habermann EB, Tuttle TM. Trends in the use of implantable accelerated partial breast irradiation therapy for early stage breast cancer in the United States. Cancer. 2011;117:3305-10.
30. Baglan KL, Sharpe MB, Jaffray D, et al. Accelerated partial breast irradiation using 3D conformal radiation therapy (3D-CRT). Int J Radiat Oncol Biol Phys. 2003;55:302-11.
31. Vicini F, Winter K, Wong J, et al. Initial efficacy results of RTOG 0319: three-dimensional conformal radiation therapy (3D-CRT) confined to the region of the lumpectomy cavity for stage I/ II breast carcinoma. Int J Radiat Oncol Biol Phys. 2010;77:1120-7.
32. Whelan TJ, Olivotto I, Parpia S, et al. Interim toxicity results from RAPID: a randomized trial of accelerated partial breast irradiation (APBI) using 3D conformal external beam radiation therapy (3D CRT). Int J Radiat Oncol Biol Phys. 2013;85:21-22.
33. Vaidya JS, Joseph DJ, Tobias JS, et al. Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial. Lancet. 2010;376:91-102.
34. Orecchia R. ELIOT Trials in Milan: Results. World Congress of Brachytherapy; Barcelona, Spain. 2012.
35. Khan AJ, Dale RG, Arthur DW, et al. Ultrashort courses of adjuvant breast radiotherapy: wave of the future or a fool's errand? Cancer. 2012;118:1962-70.
36. Vaidya JS, Tobias JS, Baum M, et al. Intraoperative radiotherapy for breast cancer. Lancet Oncol. 2004;5:165-73.
37. Taghian AG, Kozak KR, Katz A, et al. Accelerated partial breast irradiation using proton beams: Initial dosimetric experience. Int J Radiat Oncol Biol Phys. 2006;65:1404-10.
38. Kozak KR, Smith BL, Adams J, et al. Accelerated partial-breast irradiation using proton beams: initial clinical experience. Int J Radiat Oncol Biol Phys. 2006;66:691-8.
39. Bush DA, Slater JD, Garberoglio C, et al. Partial breast irradiation delivered with proton beam: results of a phase II trial. Clin Breast Cancer. 2011;11:241-5.
40. Bartelink H, Horiot JC, Poortmans PM, et al. Impact of a higher radiation dose on local control and survival in breast-conserving therapy of early breast cancer: 10-year results of the randomized boost versus no boost EORTC 22881-10882 trial. J Clin Oncol. 2007; 25:3259-65.
41. Rosenstein BS, Lymberis SC, Formenti SC. Biologic comparison of partial breast irradiation protocols. Int J Radiat Oncol Biol Phys. 2004;60:1393-404.
42. Bentzen SM, Yarnold JR. Reports of unexpected late side effects of accelerated partial breast irradiationradiobiological considerations. Int J Radiat Oncol Biol Phys. 2010;77:969-73.
43. Shaitelman SF, Vicini FA, Grills IS, et al. Differences in effective target volume between various techniques of accelerated partial breast irradiation. Int J Radiat Oncol Biol Phys. 2012;82:30-6.
44. Holland R, Veling SH, Mravunac M, Hendriks JH. Histologic multifocality of Tis, T1-2 breast carcinomas. Implications for clinical trials of breast-conserving surgery. Cancer. 1985;56:979-90.
45. Faverly DR, Hendriks JH, Holland R. Breast carcinomas of limited extent: frequency, radiologic-pathologic characteristics, and surgical margin requirements. Cancer. 2001;91:647-59.
46. Vicini FA, Kestin LL, Goldstein NS. Defining the clinical target volume for patients with early-stage breast cancer treated with lumpectomy and accelerated partial breast irradiation: a pathologic analysis. Int J Radiat Oncol Biol Phys. 2004;60:722-30.
47. Nguyen BT, Deb S, Fox S, et al. A prospective pathologic study to define the clinical target volume for partial breast radiation therapy in women with early breast cancer. Int J Radiat Oncol Biol Phys. 2012;84:1116-22.
48. Cuttino LW, Todor D, Pacyna L, et al. Three-dimensional conformal external beam radiotherapy (3D-CRT) for accelerated partial breast irradiation (APBI): what is the correct prescription dose? Am J Clin Oncol. 2006;29:474-8.
49. Wazer DE, Berle L, Graham R, et al. Preliminary results of a phase I/II study of HDR brachytherapy alone for T1/T2 breast cancer. Int J Radiat Oncol Biol Phys. 2002;53:889-97.
50. Wazer DE, Lowther D, Boyle T, et al. Clinically evident fat necrosis in women treated with high-dose-rate brachytherapy alone for early-stage breast cancer. Int J Radiat Oncol Biol Phys. 2001;50:107-11.
51. Albuquerque K, Tell D, Lobo P, et al. Impact of partial versus whole breast radiation therapy on fatigue, perceived stress, quality of life and natural killer cell activity in women with breast cancer. BMC Cancer. 2012;12:251.
52. Hattangadi J, Taback N, Neville BA, et al. Accelerated partial breast irradiation using brachytherapy for breast cancer: patterns in utilization and guideline concordance. J Natl Cancer Inst. 2012;104:1-13.
53. Smith BD, Arthur DW, Buchholz TA, et al. Accelerated partial breast irradiation consensus statement from the American Society for Radiation Oncology (ASTRO). Int J Radiat Oncol Biol Phys. 2009;74:987-1001.
54. Polgar C, Van Limbergen E, Potter R, et al. Patient selection for accelerated partial-breast irradiation (APBI) after breast-conserving surgery: recommendations of the Groupe Europeen de Curietherapie-European Society for Therapeutic Radiology and Oncology (GEC-ESTRO) breast cancer working group based on clinical evidence (2009). Radiother Oncol. 94:264-73.
55. Board of Directors ASoBS. Consenus statement for accelerated partial breast irradiation. 2011. Available from: https://www.breastsurgeons.org/statements/PDF_Statements/APBI.pdf. Accessed March 26, 2013.
56. Breast Brachytherapy Task Group, ABS. ABS Breast Brachytherapy Task Group. 2007. Available from: http://www.americanbrachytherapy.org/guidelines/abs_breast_brachytherapy_taskgroup.pdf. Accessed March 26, 2013.
57. Vicini F, Arthur D, Wazer D, et al. Limitations of the American Society of Therapeutic Radiology and Oncology Consensus Panel guidelines on the use of accelerated partial breast irradiation. Int J Radiat Oncol Biol Phys. 2011;79:977-84.
58. Shaitelman SF, Vicini FA, Beitsch P, et al. Five-year outcome of patients classified using the American Society for Radiation Oncology consensus statement guidelines for the application of accelerated partial breast irradiation: an analysis of patients treated on the American Society of Breast Surgeons MammoSite Registry Trial. Cancer. 2010;116:4677-85.
59. Wolmark N, Curran W. NSABP Protocol B-39. RTOG Protocol 0413. A randomized phase III study of conventional whole breast irradiation (WBI) versus partial breast irradiation (PBI) for women with stage 0, I, or II breast cancer. 2011. Available from: http://www.clinicaltrials.gov/ct2/show/NCT00103181. Accessed March 26, 2013.
60. Schmitz AC, Pengel KE, Loo CE, et al. Pre-treatment imaging and pathology characteristics of invasive breast cancers of limited extent: potential relevance for MRI-guided localized therapy. Radiother Oncol. 2012;104:11-8.
61. Khan AJ. Safety study for short-course accelerated, hypofractionated partial breast radiotherapy (APBI) in women with early stage breast cancer using the Contura MLB. 2010. Available from: http://clinicaltrials.gov/show/NCT01072838. Accessed March 26, 2013.
62. Palta M, Yoo S, Adamson JD, et al. Preoperative single fraction partial breast radiotherapy for early-stage breast cancer. Int J Radiat Oncol Biol Phys. 2012;82:37-42.
63. Kirby AM, Evans PM, Nerurkar AY, et al. How does knowledge of three-dimensional excision margins following breast conservation surgery impact upon clinical target volume definition for partial-breast radiotherapy? Radiother Oncol. 2010;94:292-9.
64. Hanbeukers B, Borger J, van den Ende P, et al. Customized computed tomography-based boost volumes in breast-conserving therapy: use of three-dimensional histologic information for clinical target volume margins. Int J Radiat Oncol Biol Phys. 2009;75: 757-63.
65. Stroom J, Schlief A, Alderliesten T, et al. Using histopathology breast cancer data to reduce clinical target volume margins at radiotherapy. Int J Radiat Oncol Biol Phys. 2009;74:898-905.
66. Dorn PL, Al-Hallaq HA, Haq F, et al. A prospective st6dy of the utility of magnetic resonance imaging in determining candidacy for partial breast irradiation. Int J Radiat Oncol Biol Phys. 2013;85:615-22.
67. Rampinelli C, Bellomi M, Ivaldi GB, et al. Assessment of pulmonary fibrosis after radiotherapy (RT) in breast conserving surgery: comparison between conventional external beam RT (EBRT) and intraoperative RT with electrons (ELIOT). Technol Cancer Res Treat. 2011;10:323-9.
68. Coles C, Yarnold J. The IMPORT trials are launched (September 2006). Clin Oncol (R Coll Radiol). 2006;18:587-90.
69. Yarnold J. Randomised trial testing intensity modulated and partial organ radiotherapy after breast conservation surgery for early breast cancer. 2008 [updated January 6, 2011]. Available from: http://www.clinicaltrials.gov/ct2/show/NCT00814567. Accessed March 26, 2013.
70. Strnad V, Polgár, C. Interstitial brachytherapy alone versus external beam radiation therapy after breast conserving surgery for low risk invasive carcinoma and low risk duct carcinoma in-situ (DCIS) of the female breast. Available from: http://www.apbi.uni-erlangen.de/outline/outline.html. Accessed March 26, 2013.
71. Frezza G, Bertoni, F. IRMA. Breast cancer with low risk of local recurrence: partial and accelerated radiation with three-dimensional conformal radiotherapy (3DCRT) vs. standard radiotherapy after conserving surgery (phase III study). 2007. Available from: http://groups.eortc.be/radio/res/irma/synopsis_trial_irma1.pdf. Accessed March 26, 2013.
72. Danish Breast Cancer Cooperative Group. Partial breast versus whole breast irradiation in elderly women operated on for early breast cancer. 2011. Available from: http://www.clinicaltrials.gov/ct2/show/NCT00892814. Accessed March 26, 2013.
73. Belkacemi Y, Lartigau, E. Standard or hypofractionated radiotherapy versus accelerated partial breast irradiation (APBI) for breast cancer (SHARE). 2011. Available from: http://www.clinicaltrials.gov/ct2/show/NCT01247233. Accessed March 26, 2013.
74. Livi L, Buonamici FB, Simontacchi G, et al. Accelerated partial breast irradiation with IMRT: new technical approach and interim analysis of acute toxicity in a phase III randomized clinical trial. Int J Radiat Oncol Biol Phys. 77:509-15.