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Volumn 8, Issue 4, 2013, Pages

Increased Concentrations of Glutamate and Glutamine in Normal-Appearing White Matter of Patients with Multiple Sclerosis and Normal MR Imaging Brain Scans

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE; CREATINE; GLUTAMIC ACID; GLUTAMINE; INOSITOL; N ACETYLASPARTIC ACID;

EID: 84876271669     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061817     Document Type: Article
Times cited : (59)

References (34)
  • 1
    • 0032915309 scopus 로고    scopus 로고
    • Neurodegeneration in Multiple Sclerosis: Relationship to Neurological Disability
    • Trapp BD, Ransohoff RM, Fisher E, Rudick RA, (1999) Neurodegeneration in Multiple Sclerosis: Relationship to Neurological Disability. The Neuroscientist 5: 48-57.
    • (1999) The Neuroscientist , vol.5 , pp. 48-57
    • Trapp, B.D.1    Ransohoff, R.M.2    Fisher, E.3    Rudick, R.A.4
  • 3
    • 5444240076 scopus 로고    scopus 로고
    • Recent neuropathological findings in MS - implications for diagnosis and therapy
    • Lassmann H, (2004) Recent neuropathological findings in MS- implications for diagnosis and therapy. Journal of neurology 251: 2-5.
    • (2004) Journal of Neurology , vol.251 , pp. 2-5
    • Lassmann, H.1
  • 6
    • 0035833965 scopus 로고    scopus 로고
    • Axonal loss in normal-appearing white matter in a patient with acute MS
    • Bjartmar C, Kinkel RP, Kidd G, Rudick RA, Trapp BD, (2001) Axonal loss in normal-appearing white matter in a patient with acute MS. Neurology 57: 1248-1252.
    • (2001) Neurology , vol.57 , pp. 1248-1252
    • Bjartmar, C.1    Kinkel, R.P.2    Kidd, G.3    Rudick, R.A.4    Trapp, B.D.5
  • 7
    • 0034955141 scopus 로고    scopus 로고
    • Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis
    • McDonald WI, Compston A, Edan G, Goodkin D, Hartung HP, et al. (2001) Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Annals of neurology 50: 121-127.
    • (2001) Annals of Neurology , vol.50 , pp. 121-127
    • McDonald, W.I.1    Compston, A.2    Edan, G.3    Goodkin, D.4    Hartung, H.P.5
  • 8
    • 79952501096 scopus 로고    scopus 로고
    • Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria
    • Polman CH, Reingold SC, Banwell B, Clanet M, Cohen JA, et al. (2011) Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria. Annals of neurology 69: 292-302.
    • (2011) Annals of Neurology , vol.69 , pp. 292-302
    • Polman, C.H.1    Reingold, S.C.2    Banwell, B.3    Clanet, M.4    Cohen, J.A.5
  • 9
    • 28544436950 scopus 로고    scopus 로고
    • Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria"
    • Polman CH, Reingold SC, Edan G, Filippi M, Hartung HP, et al. (2005) Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria". Annals of neurology 58: 840-846.
    • (2005) Annals of Neurology , vol.58 , pp. 840-846
    • Polman, C.H.1    Reingold, S.C.2    Edan, G.3    Filippi, M.4    Hartung, H.P.5
  • 10
    • 0036260539 scopus 로고    scopus 로고
    • The clinico-radiological paradox in multiple sclerosis revisited
    • Barkhof F, (2002) The clinico-radiological paradox in multiple sclerosis revisited. Current opinion in neurology 15: 239-245.
    • (2002) Current Opinion in Neurology , vol.15 , pp. 239-245
    • Barkhof, F.1
  • 11
    • 65349108080 scopus 로고    scopus 로고
    • Association between MRI parameters and the MS severity scale: a 12 year follow-up study
    • Minneboo A, Uitdehaag BM, Jongen P, Vrenken H, Knol D, et al. (2009) Association between MRI parameters and the MS severity scale: a 12 year follow-up study. Multiple sclerosis 15: 632-637.
    • (2009) Multiple Sclerosis , vol.15 , pp. 632-637
    • Minneboo, A.1    Uitdehaag, B.M.2    Jongen, P.3    Vrenken, H.4    Knol, D.5
  • 12
    • 77949264232 scopus 로고    scopus 로고
    • A longitudinal observational study of brain atrophy rate reflecting four decades of multiple sclerosis: a comparison of serial 1D, 2D, and volumetric measurements from MRI images
    • Martola J, Bergstrom J, Fredrikson S, Stawiarz L, Hillert J, et al. (2010) A longitudinal observational study of brain atrophy rate reflecting four decades of multiple sclerosis: a comparison of serial 1D, 2D, and volumetric measurements from MRI images. Neuroradiology 52: 109-117.
    • (2010) Neuroradiology , vol.52 , pp. 109-117
    • Martola, J.1    Bergstrom, J.2    Fredrikson, S.3    Stawiarz, L.4    Hillert, J.5
  • 13
    • 27644594658 scopus 로고    scopus 로고
    • 1H-MRS quantification of tNA and tCr in patients with multiple sclerosis: a meta-analytic review
    • Caramanos Z, Narayanan S, Arnold DL, (2005) 1H-MRS quantification of tNA and tCr in patients with multiple sclerosis: a meta-analytic review. Brain 128: 2483-2506.
    • (2005) Brain , vol.128 , pp. 2483-2506
    • Caramanos, Z.1    Narayanan, S.2    Arnold, D.L.3
  • 14
    • 12844251990 scopus 로고    scopus 로고
    • MR spectroscopic evidence for glial increase but not for neuro-axonal damage in MS normal-appearing white matter
    • Vrenken H, Barkhof F, Uitdehaag BMJ, Castelijns JA, Polman CH, et al. (2005) MR spectroscopic evidence for glial increase but not for neuro-axonal damage in MS normal-appearing white matter. Magnetic Resonance in Medicine 53: 256-266.
    • (2005) Magnetic Resonance in Medicine , vol.53 , pp. 256-266
    • Vrenken, H.1    Barkhof, F.2    Uitdehaag, B.M.J.3    Castelijns, J.A.4    Polman, C.H.5
  • 15
    • 0032585691 scopus 로고    scopus 로고
    • 1H magnetic resonance spectroscopy of normal appearing white matter in primary progressive multiple sclerosis
    • Leary SM, Davie CA, Parker GJ, Stevenson VL, Wang L, et al. (1999) 1H magnetic resonance spectroscopy of normal appearing white matter in primary progressive multiple sclerosis. Journal of neurology 246: 1023-1026.
    • (1999) Journal of Neurology , vol.246 , pp. 1023-1026
    • Leary, S.M.1    Davie, C.A.2    Parker, G.J.3    Stevenson, V.L.4    Wang, L.5
  • 16
    • 18744407587 scopus 로고    scopus 로고
    • Evidence of elevated glutamate in multiple sclerosis using magnetic resonance spectroscopy at 3 T
    • Srinivasan R, (2005) Evidence of elevated glutamate in multiple sclerosis using magnetic resonance spectroscopy at 3 T. Brain 128: 1016-1025.
    • (2005) Brain , vol.128 , pp. 1016-1025
    • Srinivasan, R.1
  • 17
    • 4344624985 scopus 로고    scopus 로고
    • Quantitative 1H-MRS of healthy human cortex, hippocampus, and thalamus: metabolite concentrations, quantification precision, and reproducibility
    • Geurts JJ, Barkhof F, Castelijns JA, Uitdehaag BM, Polman CH, et al. (2004) Quantitative 1H-MRS of healthy human cortex, hippocampus, and thalamus: metabolite concentrations, quantification precision, and reproducibility. Journal of magnetic resonance imaging: JMRI 20: 366-371.
    • (2004) Journal of Magnetic Resonance Imaging: JMRI , vol.20 , pp. 366-371
    • Geurts, J.J.1    Barkhof, F.2    Castelijns, J.A.3    Uitdehaag, B.M.4    Polman, C.H.5
  • 18
    • 84885298186 scopus 로고    scopus 로고
    • Procedure for Quantitative 1H MRS and Tissue Characterization of Human Brain Tissue Based on the Use of Quantitative MRI
    • 10.1002/mrm.24554
    • Tisell A, Dahlqvist Leinhard O, Wrantjes JBM, Lundberg P (2012) Procedure for Quantitative 1H MRS and Tissue Characterization of Human Brain Tissue Based on the Use of Quantitative MRI. Magnetic Resonance Imaging 10.1002/mrm.24554.
    • (2012) Magnetic Resonance Imaging
    • Tisell, A.1    Dahlqvist Leinhard, O.2    Wrantjes, J.B.M.3    Lundberg, P.4
  • 19
    • 0033544320 scopus 로고    scopus 로고
    • Use of the brain parenchymal fraction to measure whole brain atrophy in relapsing-remitting MS. Multiple Sclerosis Collaborative Research Group
    • Rudick RA, Fisher E, Lee JC, Simon J, Jacobs L, (1999) Use of the brain parenchymal fraction to measure whole brain atrophy in relapsing-remitting MS. Multiple Sclerosis Collaborative Research Group. Neurology 53: 1698-1704.
    • (1999) Neurology , vol.53 , pp. 1698-1704
    • Rudick, R.A.1    Fisher, E.2    Lee, J.C.3    Simon, J.4    Jacobs, L.5
  • 20
    • 34548181266 scopus 로고    scopus 로고
    • Low Choline Concentrations in Normal-Appearing White Matter of Patients with Multiple Sclerosis and Normal MR Imaging Brain Scans
    • Gustafsson MC, Dahlqvist O, Jaworski J, Lundberg P, Landtblom AME, (2007) Low Choline Concentrations in Normal-Appearing White Matter of Patients with Multiple Sclerosis and Normal MR Imaging Brain Scans. American Journal of Neuroradiology 28: 1306-1312.
    • (2007) American Journal of Neuroradiology , vol.28 , pp. 1306-1312
    • Gustafsson, M.C.1    Dahlqvist, O.2    Jaworski, J.3    Lundberg, P.4    Landtblom, A.M.E.5
  • 21
    • 84861528910 scopus 로고    scopus 로고
    • Novel whole brain segmentation and volume estimation using quantitative MRI
    • West J, Warntjes JB, Lundberg P, (2012) Novel whole brain segmentation and volume estimation using quantitative MRI. European Radiology 22: 998-1007.
    • (2012) European Radiology , vol.22 , pp. 998-1007
    • West, J.1    Warntjes, J.B.2    Lundberg, P.3
  • 23
    • 0002429690 scopus 로고
    • Absolute Quantitation of water and Metabolites in the Human Brain I. Compartments and Water
    • Ernst TR, Ross Kreis BD, (1993) Absolute Quantitation of water and Metabolites in the Human Brain I. Compartments and Water. Journal of Magnetic Resonance B 102.
    • (1993) Journal of Magnetic Resonance B , vol.102
    • Ernst, T.R.1    Ross Kreis, B.D.2
  • 24
    • 0027375098 scopus 로고
    • Estimation of metabolite concentrations from localized in vivo proton NMR spectra
    • Provencher SW, (1993) Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magnetic Resonance in Medicine 30: 672-679.
    • (1993) Magnetic Resonance in Medicine , vol.30 , pp. 672-679
    • Provencher, S.W.1
  • 25
    • 5044228017 scopus 로고    scopus 로고
    • Issues of spectral quality in clinical 1H-magnetic resonance spectroscopy and a gallery of artifacts
    • Kreis R, (2004) Issues of spectral quality in clinical 1H-magnetic resonance spectroscopy and a gallery of artifacts. NMR in biomedicine 17: 361-381.
    • (2004) NMR in Biomedicine , vol.17 , pp. 361-381
    • Kreis, R.1
  • 26
    • 33644797572 scopus 로고    scopus 로고
    • Glutamate-mediated glial injury: mechanisms and clinical importance
    • Matute C, Domercq M, Sanchez-Gomez MV, (2006) Glutamate-mediated glial injury: mechanisms and clinical importance. Glia 53: 212-224.
    • (2006) Glia , vol.53 , pp. 212-224
    • Matute, C.1    Domercq, M.2    Sanchez-Gomez, M.V.3
  • 27
    • 69249096677 scopus 로고    scopus 로고
    • Glutamate Excitotoxicity Inflicts Paranodal Myelin Splitting and Retraction
    • Fu Y, Sun W, Shi Y, Shi R, Cheng JX, (2009) Glutamate Excitotoxicity Inflicts Paranodal Myelin Splitting and Retraction. PLoS ONE 4: e6705.
    • (2009) PLoS ONE , vol.4
    • Fu, Y.1    Sun, W.2    Shi, Y.3    Shi, R.4    Cheng, J.X.5
  • 29
    • 0036136536 scopus 로고    scopus 로고
    • N-acetylaspartate is an axon-specific marker of mature white matter in vivo: a biochemical and immunohistochemical study on the rat optic nerve
    • Bjartmar C, Battistuta J, Terada N, Dupree E, Trapp BD, (2002) N-acetylaspartate is an axon-specific marker of mature white matter in vivo: a biochemical and immunohistochemical study on the rat optic nerve. Annals of neurology 51: 51-58.
    • (2002) Annals of Neurology , vol.51 , pp. 51-58
    • Bjartmar, C.1    Battistuta, J.2    Terada, N.3    Dupree, E.4    Trapp, B.D.5
  • 30
    • 0031769822 scopus 로고    scopus 로고
    • Putting magnetic resonance spectroscopy studies in context: axonal damage and disability in multiple sclerosis
    • Matthews PM, De Stefano N, Narayanan S, Francis GS, Wolinsky JS, et al. (1998) Putting magnetic resonance spectroscopy studies in context: axonal damage and disability in multiple sclerosis. Seminars in neurology 18: 327-336.
    • (1998) Seminars in Neurology , vol.18 , pp. 327-336
    • Matthews, P.M.1    De Stefano, N.2    Narayanan, S.3    Francis, G.S.4    Wolinsky, J.S.5
  • 32
    • 0027749707 scopus 로고
    • Multinuclear NMR studies on the energy metabolism of glial and neuronal cells
    • Brand A, Richter-Landsberg C, Leibfritz D, (1993) Multinuclear NMR studies on the energy metabolism of glial and neuronal cells. Developmental neuroscience 15: 289-298.
    • (1993) Developmental Neuroscience , vol.15 , pp. 289-298
    • Brand, A.1    Richter-Landsberg, C.2    Leibfritz, D.3
  • 33
    • 1642413441 scopus 로고    scopus 로고
    • Water content and myelin water fraction in multiple sclerosis - A T-2 relaxation study
    • Laule C, Vavasour IM, Moore GRW, Oger J, Li DKB, et al. (2004) Water content and myelin water fraction in multiple sclerosis- A T-2 relaxation study. Journal of neurology 251: 284-293.
    • (2004) Journal of Neurology , vol.251 , pp. 284-293
    • Laule, C.1    Vavasour, I.M.2    Moore, G.R.W.3    Oger, J.4    Li, D.K.B.5
  • 34
    • 0038375823 scopus 로고    scopus 로고
    • A longitudinal study of brain volume changes in normal aging using serial registered magnetic resonance imaging
    • Scahill RI, Frost C, Jenkins R, Whitwell JL, Rossor MN, et al. (2003) A longitudinal study of brain volume changes in normal aging using serial registered magnetic resonance imaging. Archives of neurology 60: 989-994.
    • (2003) Archives of Neurology , vol.60 , pp. 989-994
    • Scahill, R.I.1    Frost, C.2    Jenkins, R.3    Whitwell, J.L.4    Rossor, M.N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.