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Volumn 29, Issue 5, 2013, Pages 1873-1880

Progesterone inhibits the migration and invasion of A549 lung cancer cells through membrane progesterone receptor α-mediated mechanisms

Author keywords

Invasion; Lung cancer; Membrane progesterone receptor ; Migration; Progesterone

Indexed keywords

FOCAL ADHESION KINASE; GELATINASE B; MEMBRANE PROGESTERONE RECEPTOR ALPHA; PROGESTERONE; PYRAZOLOPYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 84876248056     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2013.2336     Document Type: Article
Times cited : (26)

References (48)
  • 4
    • 0025293539 scopus 로고
    • Progestin regulation of cellular proliferation
    • Clarke CL and Sutherland RL: Progestin regulation of cellular proliferation. Endocr Rev 11: 266-301, 1990. (Pubitemid 20182871)
    • (1990) Endocrine Reviews , vol.11 , Issue.2 , pp. 266-301
    • Clarke, C.L.1    Sutherland, R.L.2
  • 5
    • 0030770730 scopus 로고    scopus 로고
    • Progesterone inhibits arterial smooth muscle cell proliferation
    • DOI 10.1038/nm0997-1005
    • Lee WS, Harder JA, Yoshizumi M, Lee ME and Haber E: Progesterone inhibits arterial smooth muscle cell proliferation. Nat Med 3: 1005-1008, 1997. (Pubitemid 27391955)
    • (1997) Nature Medicine , vol.3 , Issue.9 , pp. 1005-1008
    • Lee, W.-S.1    Harder, J.A.2    Yoshizumi, M.3    Lee, M.-E.4    Haber, E.5
  • 7
    • 0035861565 scopus 로고    scopus 로고
    • Cyclin D1 overexpression induces progestin resistance in T-47D breast cancer cells despite p27(Kip1) association with cyclin E-Cdk2
    • Musgrove EA, Hunter LJ, Lee CS, Swarbrick A, Hui R and Sutherland RL: Cyclin D1 overexpression induces progestin resistance in T-47D breast cancer cells despite p27(Kip1) association with cyclin E-Cdk2. J Biol Chem 276: 47675-47683, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 47675-47683
    • Musgrove, E.A.1    Hunter, L.J.2    Lee, C.S.3    Swarbrick, A.4    Hui, R.5    Sutherland, R.L.6
  • 8
    • 0025372326 scopus 로고
    • Endocrine treatment of breast cancer in women
    • Santen RJ, Manni A, Harvey H and Redmond C: Endocrine treatment of breast cancer in women. Endocr Rev 11: 221-265, 1990. (Pubitemid 20182870)
    • (1990) Endocrine Reviews , vol.11 , Issue.2 , pp. 221-265
    • Santen, R.J.1    Manni, A.2    Harvey, H.3    Redmond, C.4
  • 10
    • 0021241328 scopus 로고
    • Better prognosis of many cancers in female: A phenomenon not explained by study of steroid receptors
    • Lee YT: Better prognosis of many cancers in female: a phenomenon not explained by study of steroid receptors. J Surg Oncol 25: 255-262, 1984.
    • (1984) J Surg Oncol , vol.25 , pp. 255-262
    • Lee, Y.T.1
  • 12
    • 77649257165 scopus 로고    scopus 로고
    • Mifepristone treatment improves length and quality of survival of mice with spontaneous lung cancer
    • Check JH, Sansoucie L, Chern J and Dix E: Mifepristone treatment improves length and quality of survival of mice with spontaneous lung cancer. Anticancer Res 30: 119-122, 2010.
    • (2010) Anticancer Res , vol.30 , pp. 119-122
    • Check, J.H.1    Sansoucie, L.2    Chern, J.3    Dix, E.4
  • 13
    • 79959907536 scopus 로고    scopus 로고
    • Progesterone and estrogen receptor expression and activity in human non-small cell lung cancer
    • Marquez-Garban DC, Mah V, Alavi M, et al: Progesterone and estrogen receptor expression and activity in human non-small cell lung cancer. Steroids 76: 910-920, 2011.
    • (2011) Steroids , vol.76 , pp. 910-920
    • Marquez-Garban, D.C.1    Mah, V.2    Alavi, M.3
  • 15
    • 0344885581 scopus 로고    scopus 로고
    • Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes
    • DOI 10.1073/pnas.0336132100
    • Zhu Y, Rice CD, Pang Y, Pace M and Thomas P: Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes. Proc Natl Acad Sci USA 100: 2231-2236, 2003. (Pubitemid 36297482)
    • (2003) Proceedings of the National Academy of Sciences of the United States of America , vol.100 , Issue.5 , pp. 2231-2236
    • Zhu, Y.1    Rice, C.D.2    Pang, Y.3    Pace, M.4    Thomas, P.5
  • 16
    • 0344885580 scopus 로고    scopus 로고
    • Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor
    • DOI 10.1073/pnas.0436133100
    • Zhu Y, Bond J and Thomas P: Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor. Proc Natl Acad Sci USA 100: 2237-2242, 2003. (Pubitemid 36297483)
    • (2003) Proceedings of the National Academy of Sciences of the United States of America , vol.100 , Issue.5 , pp. 2237-2242
    • Zhu, Y.1    Bond, J.2    Thomas, P.3
  • 17
    • 41549091710 scopus 로고    scopus 로고
    • Characteristics of membrane progestin receptor alpha (mPRalpha) and progesterone membrane receptor component 1 (PGMRC1) and their roles in mediating rapid progestin actions
    • Thomas P: Characteristics of membrane progestin receptor alpha (mPRalpha) and progesterone membrane receptor component 1 (PGMRC1) and their roles in mediating rapid progestin actions. Front Neuroendocrinol 29: 292-312, 2008.
    • (2008) Front Neuroendocrinol , vol.29 , pp. 292-312
    • Thomas, P.1
  • 18
    • 78149483425 scopus 로고    scopus 로고
    • Progesterone reverses the mesenchymal phenotypes of basal phenotype breast cancer cells via a membrane progesterone receptor mediated pathway
    • Zuo L, Li W and You S: Progesterone reverses the mesenchymal phenotypes of basal phenotype breast cancer cells via a membrane progesterone receptor mediated pathway. Breast Cancer Res 12: R34, 2010.
    • (2010) Breast Cancer Res , vol.12
    • Zuo, L.1    Li, W.2    You, S.3
  • 20
    • 70349572814 scopus 로고    scopus 로고
    • Retinal expression of Fgf2 in RCS rats with subretinal microphotodiode array
    • Ciavatta VT, Kim M, Wong P, et al: Retinal expression of Fgf2 in RCS rats with subretinal microphotodiode array. Invest Ophthalmol Vis Sci 50: 4523-4530, 2009.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 4523-4530
    • Ciavatta, V.T.1    Kim, M.2    Wong, P.3
  • 21
    • 0036707707 scopus 로고    scopus 로고
    • Doxycycline-inducible expression of SPARC/Osteonectin/BM40 in MDA-MB-231 human breast cancer cells results in growth inhibition
    • Dhanesuan N, Sharp JA, Blick T, Price JT and Thompson EW: Doxycycline-inducible expression of SPARC/Osteonectin/BM40 in MDA-MB-231 human breast cancer cells results in growth inhibition. Breast Cancer Res Treat 75: 73-85, 2002.
    • (2002) Breast Cancer Res Treat , vol.75 , pp. 73-85
    • Dhanesuan, N.1    Sharp, J.A.2    Blick, T.3    Price, J.T.4    Thompson, E.W.5
  • 22
    • 46649093214 scopus 로고    scopus 로고
    • Invadopodia and matrix degradation, a new property of prostate cancer cells during migration and invasion
    • Desai B, Ma T and Chellaiah MA: Invadopodia and matrix degradation, a new property of prostate cancer cells during migration and invasion. J Biol Chem 283: 13856-13866, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 13856-13866
    • Desai, B.1    Ma, T.2    Chellaiah, M.A.3
  • 23
    • 0022383835 scopus 로고
    • Steroid receptors in human lung cancer
    • Beattie CW, Hansen NW and Thomas PA: Steroid receptors in human lung cancer. Cancer Res 45: 4206-4214, 1985. (Pubitemid 16224875)
    • (1985) Cancer Research , vol.45 , Issue.9 , pp. 4206-4214
    • Beattie, C.W.1    Hansen, N.W.2    Thomas, P.A.3
  • 24
    • 26444533390 scopus 로고    scopus 로고
    • The significance of estrogen receptor beta in 301 surgically treated non-small cell lung cancers
    • Wu CT, Chang YL, Shih JY and Lee YC: The significance of estrogen receptor beta in 301 surgically treated non-small cell lung cancers. J Thorac Cardiovasc Surg 130: 979-986, 2005.
    • (2005) J Thorac Cardiovasc Surg , vol.130 , pp. 979-986
    • Wu, C.T.1    Chang, Y.L.2    Shih, J.Y.3    Lee, Y.C.4
  • 25
    • 0037169815 scopus 로고    scopus 로고
    • Gender-dependent expression of alpha and beta estrogen receptors in human nontumor and tumor lung tissue
    • PII S030372070100750X
    • Fasco MJ, Hurteau GJ and Spivack SD: Gender-dependent expression of alpha and beta estrogen receptors in human nontumor and tumor lung tissue. Mol Cell Endocrinol 188: 125-140, 2002. (Pubitemid 34242672)
    • (2002) Molecular and Cellular Endocrinology , vol.188 , Issue.1-2 , pp. 125-140
    • Fasco, M.J.1    Hurteau, G.J.2    Spivack, S.D.3
  • 27
    • 33846418071 scopus 로고    scopus 로고
    • Steroid and G protein binding characteristics of the seatrout and human progestin membrane receptor alpha subtypes and their evolutionary origins
    • DOI 10.1210/en.2006-0974
    • Thomas P, Pang Y, Dong J, et al: Steroid and G protein binding characteristics of the seatrout and human progestin membrane receptor alpha subtypes and their evolutionary origins. Endocrinology 148: 705-718, 2007. (Pubitemid 46143172)
    • (2007) Endocrinology , vol.148 , Issue.2 , pp. 705-718
    • Thomas, P.1    Pang, Y.2    Dong, J.3    Groenen, P.4    Kelder, J.5    De Vlieg, J.6    Zhu, Y.7    Tubbs, C.8
  • 28
    • 79959896585 scopus 로고    scopus 로고
    • Progesterone signals through membrane progesterone receptors (mPRs) in MDA-MB-468 and mPR-transfected MDA-MB-231 breast cancer cells which lack full-length and N-terminally truncated isoforms of the nuclear progesterone receptor
    • Pang Y and Thomas P: Progesterone signals through membrane progesterone receptors (mPRs) in MDA-MB-468 and mPR-transfected MDA-MB-231 breast cancer cells which lack full-length and N-terminally truncated isoforms of the nuclear progesterone receptor. Steroids 76: 921-928, 2011.
    • (2011) Steroids , vol.76 , pp. 921-928
    • Pang, Y.1    Thomas, P.2
  • 29
    • 33751500973 scopus 로고    scopus 로고
    • Human homologs of the putative G protein-coupled membrane progestin receptors (mPRalpha, beta, and gamma) localize to the endoplasmic reticulum and are not activated by progesterone
    • DOI 10.1210/me.2006-0129
    • Krietsch T, Fernandes MS, Kero J, et al: Human homologs of the putative G protein-coupled membrane progestin receptors (mPRalpha, beta, and gamma) localize to the endoplasmic reticulum and are not activated by progesterone. Mol Endocrinol 20: 3146-3164, 2006. (Pubitemid 44833562)
    • (2006) Molecular Endocrinology , vol.20 , Issue.12 , pp. 3146-3164
    • Krietsch, T.1    Fernandes, M.S.2    Kero, J.3    Losel, R.4    Heyens, M.5    Lam, E.W.-F.6    Huhtaniemi, I.7    Brosens, J.J.8    Gellersen, B.9
  • 30
    • 76149109771 scopus 로고    scopus 로고
    • Internalisation of membrane progesterone receptor-alpha after treatment with progesterone: Potential involvement of a clathrin-dependent pathway
    • Foster H, Reynolds A, Stenbeck G, Dong J, Thomas P and Karteris E: Internalisation of membrane progesterone receptor-alpha after treatment with progesterone: Potential involvement of a clathrin-dependent pathway. Mol Med Rep 3: 27-35, 2010.
    • (2010) Mol Med Rep , vol.3 , pp. 27-35
    • Foster, H.1    Reynolds, A.2    Stenbeck, G.3    Dong, J.4    Thomas, P.5    Karteris, E.6
  • 31
    • 77953551920 scopus 로고    scopus 로고
    • The key feature for early migratory processes: Dependence of adhesion, actin bundles, force generation and transmission on filopodia
    • Schafer C, Born S, Mohl C, et al: The key feature for early migratory processes: dependence of adhesion, actin bundles, force generation and transmission on filopodia. Cell Adh Migr 4: 215-225, 2010.
    • (2010) Cell Adh Migr , vol.4 , pp. 215-225
    • Schafer, C.1    Born, S.2    Mohl, C.3
  • 34
    • 44549083364 scopus 로고    scopus 로고
    • Progesterone receptor membrane component 1 - Many tasks for a versatile protein
    • Losel RM, Besong D, Peluso JJ and Wehling M: Progesterone receptor membrane component 1 - many tasks for a versatile protein. Steroids 73: 929-934, 2008.
    • (2008) Steroids , vol.73 , pp. 929-934
    • Losel, R.M.1    Besong, D.2    Peluso, J.J.3    Wehling, M.4
  • 35
    • 75749103348 scopus 로고    scopus 로고
    • Src signaling in cancer invasion
    • Guarino M: Src signaling in cancer invasion. J Cell Physiol 223: 14-26, 2010.
    • (2010) J Cell Physiol , vol.223 , pp. 14-26
    • Guarino, M.1
  • 36
    • 0030029143 scopus 로고    scopus 로고
    • Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation
    • Hanke JH, Gardner JP, Dow RL, et al: Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation. J Biol Chem 271: 695-701, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 695-701
    • Hanke, J.H.1    Gardner, J.P.2    Dow, R.L.3
  • 37
    • 0037468159 scopus 로고    scopus 로고
    • c-Src inhibitor PP1 is non-competitive against ATP
    • DOI 10.1016/S0014-5793(03)00069-3
    • Karni R, Mizrachi S, Reiss-Sklan E, Gazit A, Livnah O and Levitzki A: The pp60c-Src inhibitor PP1 is non-competitive against ATP. FEBS Lett 537: 47-52, 2003. (Pubitemid 36246674)
    • (2003) FEBS Letters , vol.537 , Issue.1-3 , pp. 47-52
    • Karni, R.1    Mizrachi, S.2    Reiss-Sklan, E.3    Gazit, A.4    Livnah, O.5    Levitzki, A.6
  • 38
    • 80455173400 scopus 로고    scopus 로고
    • Dasatinib as a single agent in triple-negative breast cancer: Results of an open-label phase 2 study
    • Finn RS, Bengala C, Ibrahim N, et al: Dasatinib as a single agent in triple-negative breast cancer: results of an open-label phase 2 study. Clin Cancer Res 17: 6905-6913, 2011.
    • (2011) Clin Cancer Res , vol.17 , pp. 6905-6913
    • Finn, R.S.1    Bengala, C.2    Ibrahim, N.3
  • 39
    • 80052505248 scopus 로고    scopus 로고
    • Src: A potential target for the treatment of triple-negative breast cancer
    • Tryfonopoulos D, Walsh S, Collins DM, et al: Src: a potential target for the treatment of triple-negative breast cancer. Ann Oncol 22: 2234-2240, 2011.
    • (2011) Ann Oncol , vol.22 , pp. 2234-2240
    • Tryfonopoulos, D.1    Walsh, S.2    Collins, D.M.3
  • 41
    • 0029039421 scopus 로고
    • Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors
    • Owens LV, Xu L, Craven RJ, et al: Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors. Cancer Res 55: 2752-2755, 1995.
    • (1995) Cancer Res , vol.55 , pp. 2752-2755
    • Owens, L.V.1    Xu, L.2    Craven, R.J.3
  • 42
    • 33745186178 scopus 로고    scopus 로고
    • The signaling and biological implications of FAK overexpression in cancer
    • Siesser PM and Hanks SK: The signaling and biological implications of FAK overexpression in cancer. Clin Cancer Res 12: 3233-3237, 2006.
    • (2006) Clin Cancer Res , vol.12 , pp. 3233-3237
    • Siesser, P.M.1    Hanks, S.K.2
  • 43
    • 79960206319 scopus 로고    scopus 로고
    • Extra-nuclear activation of progesterone receptor in regulating arterial smooth muscle cell migration
    • Hsu SP, Chen TH, Chou YP, et al: Extra-nuclear activation of progesterone receptor in regulating arterial smooth muscle cell migration. Atherosclerosis 217: 83-89, 2011.
    • (2011) Atherosclerosis , vol.217 , pp. 83-89
    • Hsu, S.P.1    Chen, T.H.2    Chou, Y.P.3
  • 46
    • 77956042544 scopus 로고    scopus 로고
    • SRC: A century of science brought to the clinic
    • Aleshin A and Finn RS: SRC: a century of science brought to the clinic. Neoplasia 12: 599-607, 2010.
    • (2010) Neoplasia , vol.12 , pp. 599-607
    • Aleshin, A.1    Finn, R.S.2
  • 47
    • 74849127935 scopus 로고    scopus 로고
    • Skp2 overexpression increases the expression of MMP-2 and MMP-9 and invasion of lung cancer cells
    • Hung WC, Tseng WL, Shiea J and Chang HC: Skp2 overexpression increases the expression of MMP-2 and MMP-9 and invasion of lung cancer cells. Cancer Lett 288: 156-161, 2010.
    • (2010) Cancer Lett , vol.288 , pp. 156-161
    • Hung, W.C.1    Tseng, W.L.2    Shiea, J.3    Chang, H.C.4
  • 48
    • 84866463562 scopus 로고    scopus 로고
    • Osthole suppresses migration and invasion of A549 human lung cancer cells through inhibition of matrix metalloproteinase-2 and matrix metallopeptidase-9 in vitro
    • Xu XM, Zhang Y, Qu D, Feng XW, Chen Y and Zhao L: Osthole suppresses migration and invasion of A549 human lung cancer cells through inhibition of matrix metalloproteinase-2 and matrix metallopeptidase-9 in vitro. Mol Med Report 6: 1018-1022, 2012.
    • (2012) Mol Med Report , vol.6 , pp. 1018-1022
    • Xu, X.M.1    Zhang, Y.2    Qu, D.3    Feng, X.W.4    Chen, Y.5    Zhao, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.